1362113-74-3
Chemical Structure
BA-AZT1
- CAS No.: 1362113-74-3
- Formula:C43H63N5O7
- Molecular Weight:761.99
InChIKey: KYFVCMJRNZFSLY-APKAFFTESA-N
SMILES: OC([C@]12[C@@]([C@@H](CC2)C(C)=C)([H])[C@]3([H])[C@@](CC1)([C@]4([C@]([C@@]5([C@@](C(C)([C@H](CC5)OCC6=CN([C@@H]7[C@H](O[C@@H](N8C(NC(C(C)=C8)=O)=O)C7)CO)N=N6)C)([H])CC4)C)([H])CC3)C)C)=O
Biological Activity: BA-AZT1 is the inhibitor for HBV polymerase and sodium taurocholate cotransporting polypeptide (NTCP). BA-AZT1 inhibits the secretion of viral capsid protein HBsAg and HBeAg with IC50 of 0.65 µM and 13.42 µM, inhibits the HBV DNA replication with an IC50 of 0.70 µM[1].
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BA-AZT1 | BA-AZT1 is the inhibitor for HBV polymerase and sodium taurocholate cotransporting polypeptide (NTCP). BA-AZT1 inhibits the secretion of viral capsid protein HBsAg and HBeAg with IC50 of 0.65 µM and 13.42 µM, inhibits the HBV DNA replication with an IC50 of 0.70 µM. | |||||||||||||||||||||
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Keywords