1 Result for "

HY-110028

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HY-110028" in MCE Product Catalog:

Leelamine hydrochloride
Leelamine hydrochloride
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Cat. No.: HY-110028
CAS No.: 16496-99-4
Purity:  99.06%
Category:  

other families Pinaceae Terpenoids Diterpenoids Plants Disease Research Fields Pinus massoniana Lamb. Endocrinology

Target:  

Cannabinoid Receptor Androgen Receptor

Leelamine hydrochloride is an orally active weakly basic amine that inhibits NPC1 and the androgen receptor AR-V7, and acts as a cannabinoid receptor agonist. Leelamine hydrochloride also functions as a lysosome affinity agent that blocks endocytosis, disrupts autophagic flux and cholesterol transport, thereby altering the RTK-AKT/STAT/MAPK signaling cascade. Leelamine hydrochloride induces cancer cell death and autophagosome accumulation, and can be used in research related to melanoma, castration-resistant prostate cancer and breast cancer .
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