1. GPCR/G Protein
    Neuronal Signaling
    Metabolic Enzyme/Protease
    Others
  2. Cannabinoid Receptor
    Fatty Acid Synthase (FAS)
    Androgen Receptor
  3. Leelamine hydrochloride

Leelamine hydrochloride 

Cat. No.: HY-110028
Handling Instructions

Leelamine hydrochloride is a tricyclic diterpene molecule that is extracted from the bark of pine trees. Leelamine hydrochloride is a cannabinoid receptor type 1 (CB1) agonist and a inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells that is not affected by androgen receptor status. Leelamine hydrochloride suppresses transcriptional activity of androgen receptor, which is known to regulate fatty acid synthesis[2,3].

For research use only. We do not sell to patients.

Leelamine hydrochloride Chemical Structure

Leelamine hydrochloride Chemical Structure

CAS No. : 16496-99-4

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Description

Leelamine hydrochloride is a tricyclic diterpene molecule that is extracted from the bark of pine trees[1]. Leelamine hydrochloride is a cannabinoid receptor type 1 (CB1) agonist and a inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells that is not affected by androgen receptor status. Leelamine hydrochloride suppresses transcriptional activity of androgen receptor, which is known to regulate fatty acid synthesis[2,3].

IC50 & Target[2]

CB1

 

Molecular Weight

321.93

Formula

C₂₀H₃₂ClN

CAS No.

16496-99-4

SMILES

NC[[email protected]]1(C)CCC[[email protected]]2(C)C3=C(CC[[email protected]@]12[H])C=C(C(C)C)C=C3.Cl

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Leelamine hydrochloride
Cat. No.:
HY-110028
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