1 Result for "

HY-112457

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HY-112457" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-112457
CAS No.: 1186648-22-5
Purity:  98.03%
Target:  

MAPKAPK2 (MK2)

Research Areas:  

Inflammation/Immunology

MK2-IN-3 hydrate (compound 16) is an orally active, selective, and ATP-competitive MAPKAP-K2 (MK-2) inhibitor with an IC50 of 8.5 nM.MK2-IN-3 hydrate is exceptional selectivity against MK-3 (IC50=0.21 μM), MK-5 (IC50=0.081 μM), ERK2 (IC50=3.44 μM), MNK1(IC50=5.7 μM) as well as CDK2, JNK2, IKK2, MSK1, and MSK2 .
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