1 Result for "

HY-N2055

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "HY-N2055" in MCE Product Catalog:

Kaempferol 3-O-sophoroside
Kaempferol 3-O-sophoroside
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Cat. No.: HY-N2055
CAS No.: 19895-95-5
Category:  

Panax ginseng C. A. Meyer Flavonols Plants other families Flavonoids Phenols Polyphenols Disease Research Fields Inflammation/Immunology Araliaceae

Target:  

Toll-like Receptor (TLR) NF-κB TNF Receptor AMPK

Kaempferol 3-O-sophoroside is an orally active derivative of Kaempferol. It exhibits anti-inflammatory, analgesic, and antidepressant effects. Kaempferol 3-O-sophoroside is an inhibitor of the cell surface receptor toll-like receptor (TLR) 2/4 for High mobility group box 1 (HMGB1), and it also exerts anti-inflammatory effects by blocking the activation of NF-κB expression and the production of TNF-α. Kaempferol 3-O-sophoroside promotes the production of brain-derived neurotrophic factor (BDNF) and enhances autophagy by binding to AMP-activated protein kinase (AMPK), thereby exerting antidepressant effects. Kaempferol 3-O-sophoroside holds promise for research in the fields of inflammation and neurodegenerative diseases .
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