1 Result for "

HY-P4821

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HY-P4821" in MCE Product Catalog:

Cat. No.: HY-P4821
CAS No.: 83139-29-1
Research Areas:  

Metabolic Disease Cancer

PTH (1-34) amide human is a type 1 PTH/PTHrP receptor agonist. PTH (1-34) amide human activates adenylate cyclase and phospholipase C pathways, thereby mediating mineral ion homeostasis and bone metabolism regulation. PTH (1-34) amide human increases serum calcium, decreases serum phosphorus, regulates renal excretion, while inducing the inhibition of endogenous PTH (1-84) and the increase of 1,25-dihydroxyvitamin D2 and bone resorption. PTH (1-34) amide human stimulates phosphatidylcholine hydrolysis via phospholipase D mediation, and its hypercalcemic effect is inhibited by human PTH-(7-84). PTH (1-34) amide human can be used in the research of diseases related to humoral hypercalcemia of malignancy .
loading...
    loading...