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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
Human Chitotriosidase
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "Human Chitotriosidase" in MCE Product Catalog:
Cat. No.: HY-P2274
CAS No.: 243975-37-3
Target:
Cat. No.: HY-120107
CAS No.: 1799548-33-6
Target:
Research Areas:
OAT-177 is a potent dual inhibitor targeting acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT1) with an IC50=14.2 nM for human AMCase and IC50=232 nM for human CHIT1. OAT-177 is promising for research of chronic inflammatory and fibrotic-related lung diseases such as asthma and idiopathic pulmonary fibrosis .
Bisdionin C is a potent GH18 chitinases inhibitor, with an IC50 of 0.2 μM for A. fumigatus ChiB1 (AfChiB1). Bisdionin C inhibits HCHT (human macrophage chitotriosidase) and acidic mammalian chitinase (AMCase) with IC50s of 8.3 and 3.4 μM, respectively .
Cat. No.: HY-P2274R
CAS No.: 243975-37-3
Category:
Target:
Cat. No.: HY-125279
CAS No.: 2221950-65-6
Target:
Research Areas:
OAT-2068 is a selective, high activity and orally active inhibitor of mouse chitotriosidase (mCHIT1) (IC50=29 nM) and displays 143-fold selectivity over m AMCase (IC50=4170 nM). OAT-2068 displays a good pharmacokinetic profile and is an ideal tool to study the role of CHIT1 in biological systems, including animal models of human diseases .
Cat. No.: HY-P76254
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CHIT1; Chitotriosidase-1; Chitinase 1; Plasma Methylumbelliferyl Tetra-N-Acetylchitotetraoside Hydrolase; CHIT; Chitotriosidase; CHI3; Chitinase-1; Chitinase 1 (Chitotriosidase); CHITD
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
