4 Results for "

IPEC-J2

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "IPEC-J2" in MCE Product Catalog:

18
Deoxynivalenol
Deoxynivalenol
0 Images
18 Cited Publications
Cat. No.: HY-N6684
CAS No.: 51481-10-8
Synonyms: Vomitoxin
Category:  

Microorganisms Terpenoids Sesquiterpenes Metabolic Disease Disease Research Fields

Target:  

P-glycoprotein

Deoxynivalenol, an orally active mycotoxin of the trichothecenes family, crosses the intestinal mucosa by a paracellular pathway through the tight junctions. The Deoxynivalenol transport is not affected by P-glycoprotein (PgP) or multidrug resistance-associated proteins (MRPs) inhibitors .
loading...
    loading...
View All Sizes
5
L-Asparagine
L-Asparagine
0 Images
5 Cited Publications
Cat. No.: HY-N0667
CAS No.: 70-47-3
Synonyms: (-)-Asparagine; Asn; Asparamide
Category:  

Neurological Disease Amino acids Endogenous metabolite Disease Research Fields Cancer

Target:  

Endogenous Metabolite Apoptosis DNA/RNA Synthesis

L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia [2] .
loading...
    loading...
View All Sizes
L-Asparagine (Standard)
L-Asparagine (Standard)
0 Images
Cat. No.: HY-N0667R
CAS No.: 70-47-3
Synonyms: (-)-Asparagine (Standard); Asn (Standard); Asparamide (Standard)
Category:  

Microorganisms Immune System Disorder Disease markers Amino acids Nervous System Disorder Endogenous metabolite Cardiovascular System Disorder Cancer

Target:  

Reference Standards Endogenous Metabolite Apoptosis DNA/RNA Synthesis

L-Asparagine (Standard) is the analytical standard of L-Asparagine (HY-N0667). This product is intended for research and analytical applications. L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia [2] .
loading...
    loading...
View All Sizes
Deoxynivalenol (Standard)
Deoxynivalenol (Standard)
0 Images
Cat. No.: HY-N6684R
CAS No.: 51481-10-8
Synonyms: Vomitoxin (Standard)
Category:  

Microorganisms Terpenoids Sesquiterpenes

Target:  

P-glycoprotein Reference Standards

Deoxynivalenol (Standard) is the analytical standard of Deoxynivalenol. This product is intended for research and analytical applications. Deoxynivalenol, an orally active mycotoxin of the trichothecenes family, crosses the intestinal mucosa by a paracellular pathway through the tight junctions. The Deoxynivalenol transport is not affected by P-glycoprotein (PgP) or multidrug resistance-associated proteins (MRPs) inhibitors .
loading...
    loading...
View All Sizes
Assay Types