189 Results for "

In vivo imaging

" in MedChemExpress (MCE) Product Catalog:
Products (189)

189 Results for "In vivo imaging" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-D1063
CAS No.: 207399-07-3
IR-780 is a near-infrared fluorescent probe for in vivo imaging of tumor cells. IR-780 is transported into tumor cells via OATPs and ABCB10, with uptake dependent on glycolytic activity and plasma membrane potential. IR-780 preferentially accumulates in tumor cell mitochondria, including those of drug-resistant cancer cells, without chemical conjugation. IR-780 generates reactive oxygen species (ROS), induces hyperthermia and apoptosis, inhibits tumor growth and recurrence, and modulates HSP70 expression upon ultrasound or 808 nm laser exposure. IR-780 acts as a sonosensitizer, photodynamic and photothermal agent, and drug delivery carrier, with low acute imaging-dose toxicity and rapid vital organ clearance. IR-780 can be used for the research of cancer, such as breast cancer, lung cancer, and non-small cell lung cancer (NSCLC) .
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4
4 Cited Publications
Cat. No.: HY-P2336A
Target:  

Melanocortin Receptor

Research Areas:  

Cancer

CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .
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3
3 Cited Publications
Cat. No.: HY-111653
CAS No.: 1247879-16-8
Purity:  99.72%
CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging .
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3
3 Cited Publications
Cat. No.: HY-135368
CAS No.: 2351898-91-2
Purity:  ≥98.0%
Target:  

Fluorescent Dye

Research Areas:  

Others

8pyDTZ is a pyridyl diphenylterazine (DTZ) analog and an ATP-independent pyridyl substrate of LumiLuc luciferase. 8pyDTZ exhibits spectrally shifted emission. 8pyDTZ has excellent biocompatibility and superior in vivo sensitivity. 8pyDTZ can be used for in vivo luminescence imaging .
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3
3 Cited Publications
Cat. No.: HY-D1389
CAS No.: 2419286-92-1
Synonyms: Sulfo-CyanIne5.5 NHS ester tripotassium
Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging .
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3
3 Cited Publications
Cat. No.: HY-D1583
CAS No.: 2360411-64-7
Synonyms: DBCO-Cy5 hexafluorophosphate; CyanIne5 dibenzocyclooctyne hexafluorophosphate
Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
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2
2 Cited Publications
Cat. No.: HY-130015
Purity:  98.99%
HKSOX-1 (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical (Ex/Em = 509/534 nm) .
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1
1 Cited Publications
Cat. No.: HY-D1041
CAS No.: 1622335-40-3
Synonyms: ICG-OSu
ICG NHS ester (ICG-OSu) is a near-infrared fluorescent agent ICG derivative. ICG NHS ester is amine-reactive and has been widely used to design in vivo imaging probes .
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1
1 Cited Publications
Cat. No.: HY-133852
CAS No.: 1151666-58-8
FD-1080 is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 can be used for in vivo imaging .
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1
1 Cited Publications
Cat. No.: HY-D1464
CAS No.: 1622250-38-7
CH1055 is a near-infrared II (NIR-II) fluorescent dye that can be used as a fluorescent probe for in vivo imaging. CH1055 can be conjugated with antibodies or ligands for specific imaging (for example the tumor imaging) .
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1
1 Cited Publications
Cat. No.: HY-133852A
CAS No.: 1151888-25-3
Purity:  96.32%
Target:  

Fluorescent Dye

Research Areas:  

Others

FD-1080 free acid is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 free acid can be used for in vivo imaging .
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1
1 Cited Publications
Cat. No.: HY-D1449
CAS No.: 155614-01-0
Target:  

Fluorescent Dye

Research Areas:  

Others

IR-1061 is a near infrared fluorescent organic dye for in vivo bimodal imaging .
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1
1 Cited Publications
Cat. No.: HY-D1719
CAS No.: 95837-47-1
Target:  

Fluorescent Dye

Research Areas:  

Others

Cypate, a cyanine dye, is a near infrared (NIR) fluorescent probe for in vivo tumor imaging .
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1
1 Cited Publications
Cat. No.: HY-122607
CAS No.: 958233-07-3
Purity:  99.86%
DPA-714 is a high affinity translocator protein (TSPO) ligand (Ki=7 nM), which is designed with a fluorine atom in its structure, allowing labelling with fluorine -18 and in vivo imaging using positron emission tomography. 18FDPA-714 successfully evaluates for the specific imaging of inflammation in various models of neuroinflammation and in a brain tumor model .
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1
1 Cited Publications
Cat. No.: HY-D1464A
CH1055 triethylamine is a near-infrared II (NIR-II) fluorescent dye that can be used as a fluorescent probe for in vivo imaging. CH1055 triethylamine can be conjugated with antibodies or ligands for specific imaging (for example the tumor imaging) .
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Cat. No.: HY-47176
CAS No.: 2883232-39-9
Target:  

Fluorescent Dye

Research Areas:  

Others

QTZ is a bioluminescence agent for in vivo imaging. QTZ has red-shifted emission and yields very little background. QTZ is a coelenterazine analog with the 4-quinolinyl substitution at the C8 position of the imidazopyrazinone core .
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Cat. No.: HY-D1873
CAS No.: 1088919-86-1
800CW acid is an orally active near-infrared (NIR) dye (excitation/emission 774/789 nm). 800CW acid can be used for intestinal permeability testing. 800CW acid can be used for in vivo imaging studies .
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Cat. No.: HY-101183
CAS No.: 1707147-26-9
Purity:  98.95%
THK5351 can be radiolabeled and used as a radiotracer for in vivo imaging of tau pathology in the brain.
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Cat. No.: HY-B0594S
CAS No.: 928623-33-0
Iohexol-d5 is deuterium labeled Iohexol. Iohexol is a radiographic contrast agent and can be applied for myelography, computerized tomography?(cisternography, ventriculography) and MicroCT imaging in vivo .
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Cat. No.: HY-P11057
Target:  

Fluorescent Dye

Research Areas:  

Others

FGGH is a water-soluble peptide-based probe. FGGH performs the sequential detection of Cu 2+ and S 2- by fluorescence and colorimetry with high sensitivity (LOD: 1.42 and 22.2 nM for Cu 2+ and S 2-, respectively) (Ex=488 nm, Em=525 nm), and images both two ions in living cells and zebrafish models with low cytotoxicity. FGGH can be used for in vivo imaging and environmental pollution monitoring research .
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