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  4. FGGH

FGGH is a water-soluble peptide-based probe. FGGH performs the sequential detection of Cu2+ and S2- by fluorescence and colorimetry with high sensitivity (LOD: 1.42 and 22.2 nM for Cu2+ and S2-, respectively) (Ex=488 nm, Em=525 nm), and images both two ions in living cells and zebrafish models with low cytotoxicity. FGGH can be used for in vivo imaging and environmental pollution monitoring research.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

FGGH

FGGH Chemical Structure

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This product is a controlled substance and not for sale in your territory.

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FGGH Related Antibodies

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Description

FGGH is a water-soluble peptide-based probe. FGGH performs the sequential detection of Cu2+ and S2- by fluorescence and colorimetry with high sensitivity (LOD: 1.42 and 22.2 nM for Cu2+ and S2-, respectively) (Ex=488 nm, Em=525 nm), and images both two ions in living cells and zebrafish models with low cytotoxicity. FGGH can be used for in vivo imaging and environmental pollution monitoring research[1].

Molecular Weight

770.81

Formula

C37H38N8O9S
Appearance

Solid

Color

Yellow to orange

Sequence

FITC-Ahx-Gly-Gly-His-NH2
Sequence Shortening

FITC-Ahx-GGH-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (32.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2973 mL 6.4867 mL 12.9734 mL
5 mM 0.2595 mL 1.2973 mL 2.5947 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.2973 mL 6.4867 mL 12.9734 mL 32.4334 mL
5 mM 0.2595 mL 1.2973 mL 2.5947 mL 6.4867 mL
10 mM 0.1297 mL 0.6487 mL 1.2973 mL 3.2433 mL
15 mM 0.0865 mL 0.4324 mL 0.8649 mL 2.1622 mL
20 mM 0.0649 mL 0.3243 mL 0.6487 mL 1.6217 mL
25 mM 0.0519 mL 0.2595 mL 0.5189 mL 1.2973 mL
30 mM 0.0432 mL 0.2162 mL 0.4324 mL 1.0811 mL
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FGGH Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FGGHFluorescent DyePeptide-based probeCu2+S2-FluorescenceColorimetryZebrafish modelsIn vivo imagingEnvironmental pollution monitoringInhibitorinhibitorinhibit

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