1247879-16-8
1247879-16-8
Chemical Structure
CycLuc1
- CAS No.: 1247879-16-8
- Formula:C13H11N3O2S2
- Molecular Weight:305.38
IUPAC Name: (S)-2-(6,7-dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid
InChIKey: HBZBAMXERPYTFS-SECBINFHSA-N
SMILES: O=C([C@@H]1N=C(C2=NC3=CC4=C(NCC4)C=C3S2)SC1)O
Biological Activity: CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging[1][2].
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CycLuc1 | 99.09% | CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging. | ||||||||||||||||||||
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CycLuc1 (Standard) | ≥98% | CycLuc1 (Standard) is the analytical standard of CycLuc1 (HY-111653). This product is intended for research and analytical applications. CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging. | ||||||||||||||||||||
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References
- [1]. Shiv K, et al. Abstract 4112: Synthetic luciferin, CycLuc1, improves bioluminescence imaging for intracranial glioblastoma xenografts. 10.1158/1538-7445.AM2018-4112
- [2]. Evans MS, et al. A synthetic luciferin improves bioluminescence imaging in live mice. Nat Methods. 2014 Apr;11(4):393-5. doi: 10.1038/nmeth.2839. Epub 2014 Feb 9. Erratum in: Nat Methods. 2014 Apr;11(4):395. [Content Brief]
