1 Result for "

JAK-IN-38

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JAK-IN-38" in MCE Product Catalog:

Cat. No.: HY-162862
Target:  

JAK

Research Areas:  

Others

JAK-IN-38 (Compound 1) is a JAK inhibitor, with IC50s of 0.03, 0.06, 0.12, 0.44 μM for Tyk2, JAK3, JAK2, JAK1 respectively. JAK-IN-38 is a collagen VII (C7) inducer and has anti-inflammatory activity. JAK-IN-38 can upregulate the expression of COL7A1 mRNA in donor-derived keratinocytes and works together with Gentamicin (HY-A0276A) to boost overall C7 levels .
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