1 Result for "

JAK2-IN-21

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JAK2-IN-21" in MCE Product Catalog:

Cat. No.: HY-183670
CAS No.: 3038340-43-8
Target:  

JAK STAT Apoptosis

Research Areas:  

Infection Cancer

JAK2-IN-21 is a Janus kinase 2 (JAK2) inhibitor with an IC50 of 12.25 nM. JAK2-IN-21 inhibits the JAK2/STAT3/STAT5 tumor-promoting signaling pathway and reduces JAK2 protein expression. JAK2-IN-21 exhibits selective cytotoxicity against HPV-positive cancer cells and induces cancer cell apoptosis. JAK2-IN-21 can be used in the research of HPV-positive cervical cancer .
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