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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
JWZ-5-13
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "JWZ-5-13" in MCE Product Catalog:
Cat. No.: HY-161828
CAS No.: 3103763-70-5
JWZ-5-13 is a CDK7 PROTAC degrader. JWZ-5-13 inhibits the proliferation of cancer cells. JWZ-5-13 is applicable to the research of ovarian cancer, diffuse large B-cell lymphoma, acute T-lymphoblastic leukemia and non-small cell lung cancer .
Cat. No.: HY-161828A
(S)-JWZ-5-13 (compound 17-Neg), a PROTAC CDK7 degrader, is a negative control compound of JWZ-5-13 (HY-161828). (S)-JWZ-5-13 displays similar in vitro CDK7 inhibition (IC50 = 21.1 nM) to JWZ-5-13, but fails to induce CDK7 degradation in cells .
Cat. No.: HY-161832
CAS No.: 3016512-69-6
Research Areas:
(S,R,S)-Me-AHPC-amide-C3-alkyne is an E3 ligase ligand-linker conjugate used for the synthesis of JWZ-5-13 (HY-161828) .
Cat. No.: HY-176978
Research Areas:
(S,S,S)-Me-AHPC-amide-C3-alkyne is an E3 ligase ligand-linker conjugate, used for the synthesis of (S)-JWZ-5-13 (HY-161828A) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
