1 Result for "

K783-0308

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "K783-0308" in MCE Product Catalog:

Cat. No.: HY-115906
CAS No.: 422554-29-8
Target:  

FLT3 MNK Apoptosis

Research Areas:  

Cancer

K783-0308 is a potent and selective dual inhibitor of FLT3 and MNK2 with IC50 values of 680 and 406 nM, respectively. K783-0308 inhibits the growth of MOLM-13 (IC50=10.5 µM) and MV-4-11 (IC50=10.4 µM) cells. K783-0308 promotes acute myeloid leukemia (AML) cell apoptosis and cell cycle arrests in the G0/G1 phase .
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