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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
KAT7
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "KAT7" in MCE Product Catalog:
15
15 Publications Verification
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WM-1119, a chemical probe, is a highly potent and selective KAT6A inhibitor, with an IC50 of 0.25 μM for KAT6A in lymphoma cells, the binding KD values of WM-1119 with KAT6A, KAT5 and KAT7 are 2 nM, 2.2 μM, 0.5 μM , respectively .
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11 Cited Publications
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WM-3835 is a potent and high-specific HBO1 (KAT7 or MYST2) inhibitor and binds directly to the acetyl-CoA binding site of HBO1. WM-3835 activates apoptosis while inhibits osteosarcoma (OS) cell proliferation, migration and invasion. WM-3835 has antitumor activity and potently inhibits pOS-1 xenograft growth in mice .
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1 Cited Publications
Cat. No.: HY-P704037
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KAT7; Histone Acetyltransferase KAT7; Prev. MYST2; ZC2HC7; HBO1; Histone Acetyltransferase MYST2; Histone Acetyltransferase Binding To ORC1; Histone Acetyltransferase; HBOA; MYST-2; MOZ, YBF2/SAS3, SAS2 And TIP60 Protein 2; HBOa; MYST Histone Acetyltransf
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Cat. No.: HY-177046
CAS No.: 3092067-21-2
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KAT6A/KAT7-IN-4 is a KAT6A and KAT7 inhibitor. KAT6A/KAT7-IN-4 has IC50 values of both ≤ 1 nM for KAT6A and KAT7. KAT6A/KAT7-IN-4 can inhibit the acetylation of H3K14 and H3K23. KAT6A/KAT7-IN-4 also inhibits tumor cell proliferation, with an IC50 of ≤ 100 nM for CAMA-1. KAT6A/KAT7-IN-4 can be used in the study of breast cancer .
Cat. No.: HY-176244
CAS No.: 1351116-34-1
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KI-TOX-A3 is a TOX protein-protein interaction inhibitor that blocks the TOX-KAT7 protein-protein interaction with an IC50 of 0.51 μM. KI-TOX-A3 induces proteasomal degradation of TOX, restores KAT7-mediated H3K14 acetylation, reverses exhaustion of CD8 + T cells, and inhibits the proliferation of T cell acute lymphoblastic leukemia (T-ALL) cells. KI-TOX-A3 shows promise for use in studies of hematological malignancies such as T-ALL .
Cat. No.: HY-177045
CAS No.: 3092066-83-3
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KAT6A/KAT7-IN-3 is a KAT6A and KAT7 inhibitor. KAT6A/KAT7-IN-3 can inhibit the acetylation of H3K14 and H3K23. KAT6A/KAT7-IN-3 also inhibits tumor cell proliferation and can be used in the study of cancer .
Cat. No.: HY-177044
CAS No.: 3092066-69-5
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KAT6A/KAT7-IN-2 is a KAT6A and KAT7 inhibitor. KAT6A/KAT7-IN-2 has IC50 values of both ≤ 1 nM for KAT6A and KAT7. KAT6A/KAT7-IN-2 can inhibit the acetylation of H3K14 and H3K23. KAT6A/KAT7-IN-2 also inhibits tumor cell proliferation. KAT6A/KAT7-IN-2 can be used in the study of cancer .
Cat. No.: HY-177043
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KAT6A/KAT7-IN-1 is a KAT6A and KAT7 inhibitor with IC50 for KAT6A of within the range of 1-10 nM, and for KAT7 of ≤ 1 nM. KAT6A/KAT7-IN-1 can inhibit the acetylation of H3K14 and H3K23. KAT6A/KAT7-IN-1 can be used in the research of breast adenocarcinoma .
Cat. No.: HY-RS07083
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KAT7 Human Pre-designed siRNA Set A contains three designed siRNAs for KAT7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16911
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Kat7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kat7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-168428
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CHI-KAT8i5 is a selective and orally active KAT8 inhibitor with a KD value of 19.72 μM. CHI-KAT8i5 does not bind to other proteins in HAT family (KAT2A, KAT2B, KAT5, and KAT7). CHI-KAT8i5 induces cancer cell apoptosis. CHI-KAT8i5 suppresses esophageal squamous cell carcinoma (ESCC) growth through targeting KAT8/c-Myc signaling pathway .
Cat. No.: HY-RS23353
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Kat7 Rat Pre-designed siRNA Set A contains three designed siRNAs for Kat7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P703009
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KAT7; Histone Acetyltransferase KAT7; Prev. MYST2; ZC2HC7; HBO1; Histone Acetyltransferase MYST2; Histone Acetyltransferase Binding To ORC1; Histone Acetyltransferase; HBOA; MYST-2; MOZ, YBF2/SAS3, SAS2 And TIP60 Protein 2; HBOa; MYST Histone Acetyltransf
Cat. No.: HY-P703008
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KAT7; Histone Acetyltransferase KAT7; Prev. MYST2; ZC2HC7; HBO1; Histone Acetyltransferase MYST2; Histone Acetyltransferase Binding To ORC1; Histone Acetyltransferase; HBOA; MYST-2; MOZ, YBF2/SAS3, SAS2 And TIP60 Protein 2; HBOa; MYST Histone Acetyltransf
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Cat. No.: HY-102058R
CAS No.: 2055397-28-7
Research Areas:
WM-1119 (Standard) is the analytical standard of WM-1119 (HY-102058). This product is intended for research and analytical applications. WM-1119, a chemical probe, is a highly potent and selective KAT6A inhibitor, with an IC50 of 0.25 μM for KAT6A in lymphoma cells, the binding Kd values of WM-1119 with KAT6A, KAT5 and KAT7 are 2 nM, 2.2 μM, 0.5 μM , respectively .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
