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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
L-PGDS
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "L-PGDS" in MCE Product Catalog:
1
1 Cited Publications
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AT-56 is a potent, selective and orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS), with an IC50 of 95 μM and Ki of 75 μM. AT-56 could selectively suppress the drowsiness or pain reaction mediated by L-PGDS-catalyzed PGD2 .
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HPGDS inhibitor 1 is a potent, selective and orally active Hematopoietic Prostaglandin D Synthase (HPGDS) inhibitor with an IC50s of 0.6 nM and 32 nM in enzyme and cellular assays, respectively. HPGDS inhibitor 1 does not inhibit human L-PGDS, mPGES, COX-1, COX-2, or 5-LOX .
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HQL-79, a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD2, and acts as an anti-allergic agent, with a Kd of 0.8 μM and an IC50 of 6 μM. Shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS .
Cat. No.: HY-13988R
CAS No.: 162640-98-4
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AT-56 (Standard) is the analytical standard of AT-56. This product is intended for research and analytical applications. AT-56 is a potent, selective and orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS), with an IC50 of 95 μM and Ki of 75 μM. AT-56 could selectively suppress the drowsiness or pain reaction mediated by L-PGDS-catalyzed PGD2 .
Cat. No.: HY-RS11374
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PTGDS Human Pre-designed siRNA Set A contains three designed siRNAs for PTGDS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-E70559
CAS No.: 65802-85-9
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Prostaglandin D synthase is a biomarker for meningioma cells and coronary artery disease. Lipocalin-type Prostaglandin D synthase (L-PGDS) is present in the atherosclerotic plaque of the human coronary artery and can be detectable in human serum .
Cat. No.: HY-P73709
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PTGDS; PGD2 Synthase; Prostaglandin D2 Synthase; Cerebrin-28; L-PGDS; PGDS2; PGDS; PDS; Glutathione-Independent PGD Synthase; Testis Tissue Sperm-Binding Protein Li 63n; Prostaglandin-H2 D-Isomerase; Prostaglandin D2 Synthase (21kD, Brain); Lipocalin-Type
Cat. No.: HY-P73710
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PTGDS; PGD2 Synthase; Prostaglandin D2 Synthase; Cerebrin-28; L-PGDS; PGDS2; PGDS; PDS; Glutathione-Independent PGD Synthase; Testis Tissue Sperm-Binding Protein Li 63n; Prostaglandin-H2 D-Isomerase; Prostaglandin D2 Synthase (21kD, Brain); Lipocalin-Type
Cat. No.: HY-P71242A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PTGDS; PGD2 Synthase; Prostaglandin D2 Synthase; Cerebrin-28; L-PGDS; PGDS2; PGDS; PDS; Glutathione-Independent PGD Synthase; Testis Tissue Sperm-Binding Protein Li 63n; Prostaglandin-H2 D-Isomerase; Prostaglandin D2 Synthase (21kD, Brain); Lipocalin-Type
Cat. No.: HY-P71242
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PTGDS; PGD2 Synthase; Prostaglandin D2 Synthase; Cerebrin-28; L-PGDS; PGDS2; PGDS; PDS; Glutathione-Independent PGD Synthase; Testis Tissue Sperm-Binding Protein Li 63n; Prostaglandin-H2 D-Isomerase; Prostaglandin D2 Synthase (21kD, Brain); Lipocalin-Type
Cat. No.: HY-RS18401
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Ptgds Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptgds gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-10439R
CAS No.: 1033836-12-2
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HPGDS inhibitor 1 (Standard) is the analytical standard of HPGDS inhibitor 1 (HY-10439). This product is intended for research and analytical applications. HPGDS inhibitor 1 is a potent, selective and orally active Hematopoietic Prostaglandin D Synthase (HPGDS) inhibitor with an IC50s of 0.6 nM and 32 nM in enzyme and cellular assays, respectively. HPGDS inhibitor 1 does not inhibit human L-PGDS, mPGES, COX-1, COX-2, or 5-LOX .
Cat. No.: HY-108259R
CAS No.: 162641-16-9
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HQL-79 (Standard) is the analytical standard of HQL-79 (HY-108259). This product is intended for research and analytical applications. HQL-79, a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD2, and acts as an anti-allergic agent, with a Kd of 0.8 μM and an IC50 of 6 μM. Shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
