Search Result

Results for "

L-Tryptophan

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (7) Amyloid-β (1) Antibiotic (1) Aryl Hydrocarbon Receptor (4) Bacterial (6) Biochemical Assay Reagents (2) Caspase (2) Cholinesterase (ChE) (1) DNA Methyltransferase (2) Drug Derivative (2) Drug Intermediate (4) Drug Isomer (1) EAAT (1) Endogenous Metabolite (26) Environmental Pollutants (1) GPR139 (1) HCV (2) iGluR (1) Indoleamine 2,3-Dioxygenase (IDO) (3) Interleukin Related (4) Isotope-Labeled Compounds (11) Mitochondrial Metabolism (2) nAChR (1) Neurokinin Receptor (2) NOD-like Receptor (NLR) (1) Prostaglandin Receptor (1) Reactive Oxygen Species (ROS) (1) Reference Standards (5) STAT (4) VEGFR (2)
By Research Areas:	Cancer (18) Cardiovascular Disease (6) Infection (9) Inflammation/Immunology (20) Metabolic Disease (16) Neurological Disease (14)
Oligonucleotides:	Solubilizing Agents (1) Freeze-drying Protective Agents (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0623

*L-Tryptophan* 10+ Cited Publications Tryptophan; Tryptophane	Environmental Pollutants	Metabolic Disease Cancer
L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels .

HY-104026

L-Kynurenine Maximum Cited Publications 25 Publications Verification	Aryl Hydrocarbon Receptor Endogenous Metabolite	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.

HY-N0623S

L-Tryptophan-d5 2 Publications Verification Tryptophan-d₅; Tryptophane-d₅	Endogenous Metabolite	Metabolic Disease
L-Tryptophan-d₅ is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-13642

RG108 10+ Cited Publications N-Phthalyl-L-Tryptophan	DNA Methyltransferase	Inflammation/Immunology Cancer
RG108 (N-Phthalyl-L-tryptophan) is a non-nucleoside DNA methyltransferases (DNMTs) inhibitor (IC₅₀=115 nM) that blocks the DNMTs active site. RG108 (N-Phthalyl-L-tryptophan) causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences .

HY-N0623S2

L-Tryptophan-13C11 1 Publications Verification Tryptophan-¹³C₁₁; Tryptophane-¹³C₁₁	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Tryptophan- ¹³C₁₁ is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-N0623R

L-Tryptophan (standard) 10+ Cited Publications Tryptophan (standard); Tryptophane (standard)	Others Reference Standards	Metabolic Disease
L-Tryptophan (standard) is the analytical standard of L-Tryptophan. L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels .

HY-104026R

L-Kynurenine (Standard) Maximum Cited Publications 25 Publications Verification	Reference Standards Aryl Hydrocarbon Receptor Endogenous Metabolite	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
L-Kynurenine (Standard) is the analytical standard of L-Kynurenine. This product is intended for research and analytical applications. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.

HY-N0707

(S)-Indoximod 1-Methyl-L-Tryptophan; (S)-NLG-8189	Indoleamine 2,3-Dioxygenase (IDO)	Neurological Disease Cancer
(S)-Indoximod (1-Methyl-L-tryptophan) is an inhibitor of indoleamine 2,3-dioxygenase (IDO) (K_i: 19 μM). (S)-Indoximod can be used for the research of cancer and neurological disease .

HY-W011978

N-Acetyl-L-tryptophan	Endogenous Metabolite Mitochondrial Metabolism Neurokinin Receptor Caspase Interleukin Related	Neurological Disease Inflammation/Immunology
N-Acetyl-L-tryptophan is an antagonist of the neurokinin-1 receptor (NK-1R), disrupting the binding of substance P (SP) to NK-1R. This action provides neuroprotective effects, improving memory deficits and motor impairments. N-Acetyl-L-tryptophan is also an inhibitor of cytochrome c (Cytochrome c), and it exerts antioxidant and anti-inflammatory effects by inhibiting the expression of IL-1β and the activation of caspase-1. N-Acetyl-L-tryptophan holds promise for research in neurodegenerative and inflammatory diseases .

HY-N1436

L-(+)-Abrine L-Abrine; L-N-MethylTryptophan; N-α-Methyl-L-Tryptophan	Others	Inflammation/Immunology
L-(+)-Abrine, a lethal albumin found in Abrus precatorius seeds, is an acute toxic alkaloid and chemical marker for abrin.

HY-104026S

L-Kynurenine-d4 1 Publications Verification	Aryl Hydrocarbon Receptor Endogenous Metabolite	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
L-Kynurenine-d₄ is the deuterium labeled L-Kynurenine. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist[1][2].

HY-19838

JNJ-63533054	GPR139	Neurological Disease
JNJ-63533054 is a potent, selective and orally active GPR139 agonist with an EC₅₀ of 16 nM for human GPR139 (hGPR139). JNJ-63533054 shows selective for GPR139 over other GPCRs, ion channels, and transporters. JNJ-63533054 can cross the blood-brain barrier (BBB) .

HY-W050025

6-Chloro-L-tryptophan	Amino Acid Derivatives	Others
6-Chloro-L-tryptophan is a Tryptophan derivative. 6-Chloro-L-tryptophan can be used as a substrate for KtzQ .

HY-13718

Oglufanide H-Glu-Trp-OH; L-Glutamyl-L-Tryptophan	VEGFR HCV Endogenous Metabolite	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Oglufanide (H-Glu-Trp-OH) is a dipeptide immunomodulator isolated from calf thymus. Oglufanide inhibits vascular endothelial growth factor (VEGF). Oglufanide can stimulate the immune response to hepatitic C virus (HCV) and intracellular bacterial infections. Oglufanide shows antitumor and anti-angiogenesis activities .

HY-N0623S1

L-Tryptophan-13C 1 Publications Verification Tryptophan-¹³C; Tryptophane-¹³C	Endogenous Metabolite	Metabolic Disease
L-Tryptophan- ¹³C is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-N0623S3

L-Tryptophan-1-13C Tryptophan-1-¹³C; Tryptophane-1-¹³C	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Tryptophan-1- ¹³C is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-N0623S5

L-Tryptophan-d8 Tryptophan-d₈; Tryptophane-d₈	Endogenous Metabolite	Metabolic Disease
L-Tryptophan-d₈ is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-N0623S9

L-Tryptophan-d3 Tryptophan-d₃; Tryptophane-d₃	Endogenous Metabolite	Metabolic Disease
L-Tryptophan-d₃ is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-W009706

Alclofenac Allopydin; W-7320	Prostaglandin Receptor	Neurological Disease Inflammation/Immunology
Alclofenac (Allopydin) is an orally active prostaglandin synthase inhibitor with anti-inflammatory, analgesic and antipyretic activities. Alclofenac irreversibly inhibits platelet aggregation. Alclofenac can be used in research related to rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, low back pain and sciatica .

HY-N0623S8

L-Tryptophan-15N2 Tryptophan-¹⁵N₂; Tryptophane-¹⁵N₂	Endogenous Metabolite	Metabolic Disease
L-Tryptophan- ¹⁵N₂ is the ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-20897A

5-Bromo-L-tryptophan 1 Publications Verification	Endogenous Metabolite Amino Acid Derivatives Drug Intermediate	Others
5-Bromo-L-tryptophan is an α-amino acid derivative that can be found in Semenospongia sp.. 5-Bromo-L-tryptophan can be used to synthesize 5-bromoindole (HY-30236) .

HY-21045

5-Fluoro-L-tryptophan L-5-FluoroTryptophan	EAAT	Neurological Disease
5-Fluoro-L-tryptophan is a competitive vesicular glutamate transporter (VGLUT) inhibitor. 5-Fluoro-L-tryptophan is promising for research of diseases associated with the neurotransmitter systems .

HY-N0623S7

L-Tryptophan-15N Tryptophan-¹⁵N; Tryptophane-¹⁵N	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Tryptophan- ¹⁵N is the ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0623S4

L-Tryptophan-13C11,15N2 Tryptophan-¹³C₁₁,¹⁵N₂; Tryptophane-¹³C₁₁,¹⁵N₂	Endogenous Metabolite	Metabolic Disease
L-Tryptophan- ¹³C₁₁, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-20899

6-Bromo-L-tryptophan 6BrW	Bacterial	Others
6-Bromo-L-tryptophan (6BrW) is a compound that can be incorporated into recombinant proteins by a specific system in bacterial cells, causing a blue shift in fluorescence emission and absorption maxima.

HY-104026S1

L-Kynurenine-d4-1	Aryl Hydrocarbon Receptor Endogenous Metabolite	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
L-Kynurenine-d₄-1 is deuterium labeled L-Kynurenine. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.

HY-W007328

5-Methoxyindole	Endogenous Metabolite Drug Intermediate	Inflammation/Immunology Cancer
5-Methoxyindole is an endogenous compound with significant biological activity, which is produced by the metabolism of L-tryptophan. 5-Methoxyindole can be used as a drug intermediate to synthesize 5-methoxytryptophan and N-acetyl 5-methoxytryptamine, and it exhibits anti-cancer and anti-inflammatory activities.

HY-W654331

Quinolinic acid-13C3, 15N 2,3-Pyridinedicarboxylic Acid-¹³C₃,¹⁵N	Isotope-Labeled Compounds iGluR Endogenous Metabolite	Inflammation/Immunology
Quinolinic acid- ¹³C₃, ¹⁵N (2,3-Pyridinedicarboxylic Acid- ¹³C₃, ¹⁵N) is the ¹³C- and ¹⁵N-labeled Quinolinic acid (HY-100807). Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction .

HY-W011607

L-Alanyl-L-tryptophan	Amino Acid Derivatives	Others
L-Alanyl-L-tryptophan is a dipeptide formed from L-alanyl and L-tryptophan, and is also a metabolite. L-Alanyl-L-tryptophan can be adsorbated on the surface of gold nanoparticles, and the Raman signal can be enhanced by SERS technology to obtain the enhanced Raman spectroscopy .

HY-P2876

Tryptophanase	Bacterial	Others
Tryptophanase is a zymogen-converting enzyme and inducible enzyme that can convert its inactive precursor form into an active enzyme without additional polypeptide synthesis. In Escherichia coli K12, tryptophanase functions as an inducible enzyme, and its induction kinetics are similar to those of β-galactosidase. Tryptophanase catalyzes the conversion of L-tryptophan to indole .

HY-N0623S10

L-Phenylalanine,Indole-15N	Endogenous Metabolite	Metabolic Disease Cancer
L-Phenylalanine,Indole- ¹⁵N is the ¹⁵N labeled L-Tryptophan[1]. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[2].

HY-14743B

Golotimod hydrochloride SCV 07 hydrochloride; Gamma-D-glutamyl-L-Tryptophan hydrochloride	Bacterial STAT	Infection Inflammation/Immunology Cancer
Golotimod hydrochloride (SCV 07 hydrochloride), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod hydrochloride (SCV 07 hydrochloride) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod hydrochloride (SCV 07 hydrochloride) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) .

HY-104026S2

L-Kynurenine-d4-1 hydrochloride	Isotope-Labeled Compounds	Cancer
L-Kynurenine-d₄-1 hydrochloride is the deuterium labeled L-Kynurenine (HY-104026). L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist .

HY-W143241

Glycyl-L-tryptophan H-Gly-Trp-OH; Gly-Trp	Amino Acid Derivatives	Others
Glycyl-L-tryptophan is a polypeptide .

HY-171746

F4-Trp 4,5,6,7-Tetrafluoro-L-Tryptophan	nAChR	Neurological Disease
F4-Trp (4,5,6,7-Tetrafluoro-L-tryptophan) is a ligand targeting the α3β4 nicotinic acetylcholine receptor (α3β4 nAChR). F4-Trp is promising for research of neurotransmission, addiction, and related diseases, such as neurological diseases .

HY-14743

Golotimod SCV 07; Gamma-D-glutamyl-L-Tryptophan	Bacterial STAT	Infection Inflammation/Immunology Cancer
Golotimod (SCV-07), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod (SCV-07) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod (SCV-07) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) .

HY-W585843

*1,1′-Ethylidenebis[L-tryptophan]*	Interleukin Related	Inflammation/Immunology
1,1′-Ethylidenebis[L-tryptophan] is an impurity in the synthesis of L-tryptophan. 1,1′-Ethylidenebis[L-tryptophan] promotes the proliferation of eosinophilic leukemia cells, induces the release of eosinophil cationic protein from eosinophils, and stimulates T cells to produce IL-5. 1,1′-Ethylidenebis[L-tryptophan] (40 µg/kg) can induce fascia thickening, mast cell infiltration, and fibrosis in adipose and subcutaneous muscle tissues in mice. 1,1′-Ethylidenebis[L-tryptophan] can be used in immunology and inflammation research .

HY-W585845

*2-Hydroxy L-tryptophan* hydrochloride**	Endogenous Metabolite	Neurological Disease
2-Hydroxy L-tryptophan hydrochloride is a naturally found amino acid that serves as a precursor to serotonin. 2-Hydroxy L-tryptophan hydrochloride involves enhancing serotonin production within the brain. Serotonin is a neurotransmitter responsible for regulating mood, appetite, and sleep, benefits from the increased levels facilitated by 2-Hydroxy L-tryptophan hydrochloride.

HY-W011978S

*N-Acetyl-L-tryptophan-d3*	Isotope-Labeled Compounds Endogenous Metabolite Mitochondrial Metabolism Neurokinin Receptor Caspase Interleukin Related	Neurological Disease Inflammation/Immunology
N-Acetyl-L-tryptophan-d₃ is the deuterium labeled N-Acetyl-L-tryptophan (HY-W011978). N-Acetyl-L-tryptophan is an antagonist of the neurokinin-1 receptor (NK-1R), disrupting the binding of substance P (SP) to NK-1R. This action provides neuroprotective effects, improving memory deficits and motor impairments. N-Acetyl-L-tryptophan is also an inhibitor of cytochrome c (Cytochrome c), and it exerts antioxidant and anti-inflammatory effects by inhibiting the expression of IL-1β and the activation of caspase-1. N-Acetyl-L-tryptophan holds promise for research in neurodegenerative and inflammatory diseases .

HY-W674285

Oxindolylalanine	Amino Acid Derivatives	Metabolic Disease
Oxindolylalanine, a tryptophan analogue, is an inhibitor of tryptophan indole-lyase (K_i: 5 μM) and tryptophan synthase. Tryptophan indole-lyase is a bacterial enzyme which catalyzes the reversible formation of indole and ammonium pyruvate from L-tryptophan.

HY-104026S3

L-Kynurenine-13C4,15N-1	Isotope-Labeled Compounds	Cancer
L-Kynurenine- ¹³C₄, ¹⁵N-1 is the ¹³C and ¹⁵N labled L-Kynurenine (HY-104026) . L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.

HY-N0707S

(S)-Indoximod-d3 1-Methyl-L-Tryptophan-d₃; (S)-NLG-8189-d₃	Indoleamine 2,3-Dioxygenase (IDO)	Cancer
(S)-Indoximod-d₃ is the deuterium labeled (S)-Indoximod. (S)-Indoximod (1-Methyl-L-tryptophan) is an inhibitor of indoleamine 2,3-dioxygenase (IDO). (S)-Indoximod can be used for the research of cancer .

HY-N0623S6

L-Tryptophan-15N2,d8 Tryptophan-¹⁵N₂,d₈; Tryptophane-¹⁵N₂,d₈	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Tryptophan- ¹⁵N₂,d₈ is the deuterium and ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-W011978R

*N-Acetyl-L-tryptophan* (Standard)**	Reference Standards Endogenous Metabolite	Metabolic Disease
N-Acetyl-L-tryptophan (Standard) is the analytical standard of N-Acetyl-L-tryptophan. This product is intended for research and analytical applications. N-Acetyl-L-tryptophan is an endogenous metabolite.

HY-W585887

Fructose-L-tryptophan Trp-Fru	Biochemical Assay Reagents	Others
Fructose-L-tryptophan (Trp-Fru), an early Maillard reaction product formed from tryptophan and glucose .

HY-20897AR

*5-Bromo-L-tryptophan* (Standard)**	Reference Standards Endogenous Metabolite Amino Acid Derivatives Drug Intermediate	Others
5-Bromo-L-tryptophan (Standard) is the analytical standard of 5-Bromo-L-tryptophan (HY-20897A). This product is intended for research and analytical applications. 5-Bromo-L-tryptophan is an α-amino acid derivative that can be found in Semenospongia sp.. 5-Bromo-L-tryptophan can be used to synthesize 5-bromoindole (HY-30236).

HY-W720532

*N,N-Dimethyl-L-tryptophan* hydrochloride**	Drug Derivative	Neurological Disease
N,N-Dimethyl-L-tryptophan hydrochloride is a tryptamine.

HY-135597

N-Acetyl-5-methyl-L-tryptophan	Drug Isomer	Others
N-Acetyl-5-methyl-L-tryptophan is a N-Acetyl-L-tryptophan analog.

HY-13642A

(Rac)-RG108 (Rac)-N-Phthalyl-L-Tryptophan	DNA Methyltransferase	Others
(Rac)-RG108 (NSC401077), a DNMT1 inhibitor, inhibits DNA methyltransferases .

HY-142127S

*2-(α-D-Mannopyranosyl)-L-tryptophan-d4*	Isotope-Labeled Compounds Antibiotic	Others
2-(α-D-Mannopyranosyl)-L-tryptophan-d₄ is the deuterium labeled 2-(α-D-Mannopyranosyl)-L-tryptophan .

Cat. No.	Product Name	Type

HY-W007328

5-Methoxyindole	Biochemical Assay Reagents
5-Methoxyindole is an endogenous compound with significant biological activity, which is produced by the metabolism of L-tryptophan. 5-Methoxyindole can be used as a drug intermediate to synthesize 5-methoxytryptophan and N-acetyl 5-methoxytryptamine, and it exhibits anti-cancer and anti-inflammatory activities.

HY-W585887

Fructose-L-tryptophan Trp-Fru	Biochemical Assay Reagents
Fructose-L-tryptophan (Trp-Fru), an early Maillard reaction product formed from tryptophan and glucose .

Cat. No.	Product Name	Target	Research Area

HY-W050025

6-Chloro-L-tryptophan	Amino Acid Derivatives	Others
6-Chloro-L-tryptophan is a Tryptophan derivative. 6-Chloro-L-tryptophan can be used as a substrate for KtzQ .

HY-13718

Oglufanide H-Glu-Trp-OH; L-Glutamyl-L-Tryptophan	VEGFR HCV Endogenous Metabolite	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Oglufanide (H-Glu-Trp-OH) is a dipeptide immunomodulator isolated from calf thymus. Oglufanide inhibits vascular endothelial growth factor (VEGF). Oglufanide can stimulate the immune response to hepatitic C virus (HCV) and intracellular bacterial infections. Oglufanide shows antitumor and anti-angiogenesis activities .

HY-20897A

5-Bromo-L-tryptophan 1 Publications Verification	Endogenous Metabolite Amino Acid Derivatives Drug Intermediate	Others
5-Bromo-L-tryptophan is an α-amino acid derivative that can be found in Semenospongia sp.. 5-Bromo-L-tryptophan can be used to synthesize 5-bromoindole (HY-30236) .

HY-W143241

Glycyl-L-tryptophan H-Gly-Trp-OH; Gly-Trp	Amino Acid Derivatives	Others
Glycyl-L-tryptophan is a polypeptide .

HY-171746

F4-Trp 4,5,6,7-Tetrafluoro-L-Tryptophan	nAChR	Neurological Disease
F4-Trp (4,5,6,7-Tetrafluoro-L-tryptophan) is a ligand targeting the α3β4 nicotinic acetylcholine receptor (α3β4 nAChR). F4-Trp is promising for research of neurotransmission, addiction, and related diseases, such as neurological diseases .

HY-14743

Golotimod SCV 07; Gamma-D-glutamyl-L-Tryptophan	Bacterial STAT	Infection Inflammation/Immunology Cancer
Golotimod (SCV-07), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod (SCV-07) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod (SCV-07) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) .

HY-20897AR

*5-Bromo-L-tryptophan* (Standard)**	Reference Standards Endogenous Metabolite Amino Acid Derivatives Drug Intermediate	Others
5-Bromo-L-tryptophan (Standard) is the analytical standard of 5-Bromo-L-tryptophan (HY-20897A). This product is intended for research and analytical applications. 5-Bromo-L-tryptophan is an α-amino acid derivative that can be found in Semenospongia sp.. 5-Bromo-L-tryptophan can be used to synthesize 5-bromoindole (HY-30236).

HY-14743R

Golotimod (Standard) SCV 07 (Standard); Gamma-D-glutamyl-L-Tryptophan (Standard)	Bacterial STAT Reference Standards	Infection Inflammation/Immunology Cancer
Golotimod (Standard) is the analytical standard of Golotimod. This product is intended for research and analytical applications. Golotimod (SCV-07), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod (SCV-07) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod (SCV-07) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0623

*L-Tryptophan* 10+ Cited Publications Tryptophan; Tryptophane	Structural Classification Classification of Application Fields Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields Source Classification Cancer	Environmental Pollutants
L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels .

HY-104026

L-Kynurenine Maximum Cited Publications 25 Publications Verification	Cardiovascular Disease Structural Classification Human Gut Microbiota Metabolites Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields	Aryl Hydrocarbon Receptor Endogenous Metabolite
L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.

HY-N0623R

L-Tryptophan (standard) 10+ Cited Publications Tryptophan (standard); Tryptophane (standard)	Structural Classification Alkaloids Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Others Reference Standards
L-Tryptophan (standard) is the analytical standard of L-Tryptophan. L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels .

HY-104026R

L-Kynurenine (Standard) Maximum Cited Publications 25 Publications Verification	Structural Classification Alkaloids Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Aryl Hydrocarbon Receptor Endogenous Metabolite
L-Kynurenine (Standard) is the analytical standard of L-Kynurenine. This product is intended for research and analytical applications. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.

HY-N0707

(S)-Indoximod 1-Methyl-L-Tryptophan; (S)-NLG-8189	Classification of Application Fields Leguminosae Ketones, Aldehydes, Acids Abrus precatorius Linn. Plants Disease Research Fields Source Classification Cancer	Indoleamine 2,3-Dioxygenase (IDO)
(S)-Indoximod (1-Methyl-L-tryptophan) is an inhibitor of indoleamine 2,3-dioxygenase (IDO) (K_i: 19 μM). (S)-Indoximod can be used for the research of cancer and neurological disease .

HY-W011978

N-Acetyl-L-tryptophan	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Mitochondrial Metabolism Neurokinin Receptor Caspase Interleukin Related
N-Acetyl-L-tryptophan is an antagonist of the neurokinin-1 receptor (NK-1R), disrupting the binding of substance P (SP) to NK-1R. This action provides neuroprotective effects, improving memory deficits and motor impairments. N-Acetyl-L-tryptophan is also an inhibitor of cytochrome c (Cytochrome c), and it exerts antioxidant and anti-inflammatory effects by inhibiting the expression of IL-1β and the activation of caspase-1. N-Acetyl-L-tryptophan holds promise for research in neurodegenerative and inflammatory diseases .

HY-N1436

L-(+)-Abrine L-Abrine; L-N-MethylTryptophan; N-α-Methyl-L-Tryptophan	Alkaloids Classification of Application Fields Leguminosae Abrus precatorius Linn. Plants Inflammation/Immunology Disease Research Fields Indole Alkaloids Source Classification	Others
L-(+)-Abrine, a lethal albumin found in Abrus precatorius seeds, is an acute toxic alkaloid and chemical marker for abrin.

HY-13718

Oglufanide H-Glu-Trp-OH; L-Glutamyl-L-Tryptophan	Cardiovascular Disease Classification of Application Fields Animals Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	VEGFR HCV Endogenous Metabolite
Oglufanide (H-Glu-Trp-OH) is a dipeptide immunomodulator isolated from calf thymus. Oglufanide inhibits vascular endothelial growth factor (VEGF). Oglufanide can stimulate the immune response to hepatitic C virus (HCV) and intracellular bacterial infections. Oglufanide shows antitumor and anti-angiogenesis activities .

HY-20897A

5-Bromo-L-tryptophan 1 Publications Verification	Structural Classification Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Amino Acid Derivatives Drug Intermediate
5-Bromo-L-tryptophan is an α-amino acid derivative that can be found in Semenospongia sp.. 5-Bromo-L-tryptophan can be used to synthesize 5-bromoindole (HY-30236) .

HY-W011978R

*N-Acetyl-L-tryptophan* (Standard)**	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
N-Acetyl-L-tryptophan (Standard) is the analytical standard of N-Acetyl-L-tryptophan. This product is intended for research and analytical applications. N-Acetyl-L-tryptophan is an endogenous metabolite.

HY-20897AR

*5-Bromo-L-tryptophan* (Standard)**	Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Amino Acid Derivatives Drug Intermediate
5-Bromo-L-tryptophan (Standard) is the analytical standard of 5-Bromo-L-tryptophan (HY-20897A). This product is intended for research and analytical applications. 5-Bromo-L-tryptophan is an α-amino acid derivative that can be found in Semenospongia sp.. 5-Bromo-L-tryptophan can be used to synthesize 5-bromoindole (HY-30236).

Cat. No.	Product Name	Chemical Structure

HY-N0623S

L-Tryptophan-d5 2 Publications Verification
L-Tryptophan-d₅ is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-N0623S2

L-Tryptophan-13C11 1 Publications Verification
L-Tryptophan- ¹³C₁₁ is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-104026S

L-Kynurenine-d4 1 Publications Verification
L-Kynurenine-d₄ is the deuterium labeled L-Kynurenine. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist[1][2].

HY-N0623S1

L-Tryptophan-13C 1 Publications Verification
L-Tryptophan- ¹³C is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-N0623S3

L-Tryptophan-1-13C
L-Tryptophan-1- ¹³C is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-N0623S5

L-Tryptophan-d8
L-Tryptophan-d₈ is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-N0623S9

L-Tryptophan-d3
L-Tryptophan-d₃ is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-N0623S8

L-Tryptophan-15N2
L-Tryptophan- ¹⁵N₂ is the ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-N0623S7

L-Tryptophan-15N
L-Tryptophan- ¹⁵N is the ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0623S4

L-Tryptophan-13C11,15N2
L-Tryptophan- ¹³C₁₁, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-104026S1

L-Kynurenine-d4-1
L-Kynurenine-d₄-1 is deuterium labeled L-Kynurenine. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.

HY-W654331

Quinolinic acid-13C3, 15N
Quinolinic acid- ¹³C₃, ¹⁵N (2,3-Pyridinedicarboxylic Acid- ¹³C₃, ¹⁵N) is the ¹³C- and ¹⁵N-labeled Quinolinic acid (HY-100807). Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction .

HY-N0623S10

L-Phenylalanine,Indole-15N
L-Phenylalanine,Indole- ¹⁵N is the ¹⁵N labeled L-Tryptophan[1]. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[2].

HY-104026S2

L-Kynurenine-d4-1 hydrochloride
L-Kynurenine-d₄-1 hydrochloride is the deuterium labeled L-Kynurenine (HY-104026). L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist .

HY-W011978S

N-Acetyl-L-tryptophan-d3

N-Acetyl-L-tryptophan-d₃ is the deuterium labeled N-Acetyl-L-tryptophan (HY-W011978). N-Acetyl-L-tryptophan is an antagonist of the neurokinin-1 receptor (NK-1R), disrupting the binding of substance P (SP) to NK-1R. This action provides neuroprotective effects, improving memory deficits and motor impairments. N-Acetyl-L-tryptophan is also an inhibitor of cytochrome c (Cytochrome c), and it exerts antioxidant and anti-inflammatory effects by inhibiting the expression of IL-1β and the activation of caspase-1. N-Acetyl-L-tryptophan holds promise for research in neurodegenerative and inflammatory diseases .

HY-104026S3

L-Kynurenine-13C4,15N-1
L-Kynurenine- ¹³C₄, ¹⁵N-1 is the ¹³C and ¹⁵N labled L-Kynurenine (HY-104026) . L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.

HY-N0707S

(S)-Indoximod-d3
(S)-Indoximod-d₃ is the deuterium labeled (S)-Indoximod. (S)-Indoximod (1-Methyl-L-tryptophan) is an inhibitor of indoleamine 2,3-dioxygenase (IDO). (S)-Indoximod can be used for the research of cancer .

HY-N0623S6

L-Tryptophan-15N2,d8
L-Tryptophan- ¹⁵N₂,d₈ is the deuterium and ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

HY-142127S

*2-(α-D-Mannopyranosyl)-L-tryptophan-d4*
2-(α-D-Mannopyranosyl)-L-tryptophan-d₄ is the deuterium labeled 2-(α-D-Mannopyranosyl)-L-tryptophan .

HY-146628S

*5-Hydroxy-L-tryptophan-4,6,7-d3*
5-Hydroxy-L-tryptophan-4,6,7-d₃ is the deuterium labeled 5-Hydroxy-L-tryptophan-4,6,7 .

HY-W007328S

5-Methoxyindole-d3
5-Methoxyindole-d₃ is the deuterium labeled 5-Methoxyindole (HY-W007328). 5-Methoxyindole is an endogenous compound with significant biological activity, which is produced by the metabolism of L-tryptophan. 5-Methoxyindole can be used as a drug intermediate to synthesize 5-methoxytryptophan and N-acetyl 5-methoxytryptamine, and it exhibits anti-cancer and anti-inflammatory activities.

Cat. No.	Product Name		Classification

HY-N0623

*L-Tryptophan* 10+ Cited Publications Tryptophan; Tryptophane		Freeze-drying Protective Agents Solubilizing Agents
L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

L-Tryptophan

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Oligonucleotides

Natural
Products