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LIM kinase 1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	LIM Kinase (LIMK) (3)
By Research Areas:	Cancer (2) Neurological Disease (2)

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Antibodies

Targets Recommended: LIM Kinase (LIMK)

Cat. No.	Nom du produit	Target	Áreas de investigación	Chemical Structure

HY-19353

SR7826 1 Publications Verification	LIM Kinase (LIMK)	Neurological Disease Cancer
SR7826 is a class of bis-aryl urea derived potent, selective and orally active LIM kinase (LIMK) inhibitor with an IC₅₀ of 43 nM for LIMK1. SR7826 is >100-fold more selective for LIMK1 than ROCK and JNK kinases .

HY-151539

TH470	LIM Kinase (LIMK)	Neurological Disease
TH470 is a highly selective LIMK1/2 (LIM *kinase1/2) inhibitor (LIMK1 IC₅₀=9.8 nM; LIMK2 IC₅₀*=13 nM), and can be used in orphan disease research .

HY-N8669

Curcolonol	LIM Kinase (LIMK)	Cancer
Curcolonol is a furan type sesquiterpene. Curcolonol can be isolated from several medical herbs. Curcolonol has inhibitory activity for **LIM kinase 1**. Curcolonol can be used for the research of breast cancer .

Curcolonol	Terpenoids Sesquiterpenes Plants Curcuma phaeocaulis Valeton Source Classification Zingiberaceae	LIM Kinase (LIMK)
Curcolonol is a furan type sesquiterpene. Curcolonol can be isolated from several medical herbs. Curcolonol has inhibitory activity for **LIM kinase 1**. Curcolonol can be used for the research of breast cancer .

Species:	Human (3)
Tag:	His (2) Tag Free (1) GST (1)
Source:	sf9 insect cells (1) Sf9 insect cells (2)

Cat. No.	Compare	Nom du produit	Species	Source	Image

HY-P705847

	LIMK1 Protein, Human (sf9, His-GST) LIMK1; LIM domain kinase 1; LIMK-1	Human	sf9 insect cells

HY-P701792

	LIMK1 Protein, Human (D460N, sf9) LIMK1; LIM domain kinase 1; LIMK-1	Human	Sf9 insect cells
	The LIMK1 protein is an important serine/threonine protein kinase that controls actin dynamics downstream of Rho GTPases. Activation of ROCK1, PAK1, and PAK4 phosphorylates LIMK1, allowing it to phosphorylate and inhibit actin depolymerizing factors, including cofilin-1/CFL1 and destrin/DSTN. LIMK1 Protein, Human (D460N, sf9) is the recombinant human-derived LIMK1 protein, expressed by sf9 insect cells , with tag free.

HY-P701793

	LIMK1 Protein, Human (D460N, sf9, His) LIMK1; LIM domain kinase 1; LIMK-1	Human	Sf9 insect cells
	The LIMK1 protein is an important serine/threonine protein kinase that controls actin dynamics downstream of Rho GTPases. Activation of ROCK1, PAK1, and PAK4 phosphorylates LIMK1, allowing it to phosphorylate and inhibit actin depolymerizing factors, including cofilin-1/CFL1 and destrin/DSTN. LIMK1 Protein, Human (D460N, sf9, His) is the recombinant human-derived LIMK1 protein, expressed by sf9 insect cells , with N-8*His labeled tag.

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Host:	Mouse (1) Rabbit (3)
Reactivity:	Human (4) Rat (3) Mouse (4) Monkey (1)
Application:	IHC-P (2) ICC/IF (2) WB (4) FC (1) ELISA (2)
Isotype:	IgG (3) IgG1 (1)
Conjugation:	Non-conjugated (4)
Clonality:	polyclonal (1) Monoclonal (3) Recombinant (2)
Modification:	Unmodified (4)

Cat. No.	Compare	Nom du produit	Application	Reactivity	Image

HY-P81941

	LIM Kinase 1 Antibody (YA1686) LIMK1; LIMK; LIM domain kinase 1; LIMK-1	WB	Human, Mouse
	LIM Kinase 1 Antibody (YA1686) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LIM Kinase 1.

HY-P810507

	*Phospho-LIM* Kinase 1 (Thr508) Antibody**	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat
	Phospho-LIM Kinase 1 (Thr508) Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Phospho-LIM Kinase 1(Thr508).

HY-P85864

	LIM Kinase 1+2 Antibody (YA5556) LIM domain kinase 1; LIMK-1;	WB, ICC/IF, ELISA	Human, Mouse, Rat
	LIM Kinase 1+2 Antibody (YA5556) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LIM Kinase 1+2.

HY-P810393

	LIM Kinase 1 Antibody (YA9710) EC 2.7.1.37, LIM domain containing protein kinase, LIM domain kinase 1, LIM kinase, LIM motif containing protein kinase, LIMK 1, LIMK, LIMK-1, LIMk1, LIMK1_HUMAN	WB, IHC-P, FC	Human, Mouse, Rat, Monkey
	LIM Kinase 1 Antibody (YA9710) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to LIM Kinase 1.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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