1219728-20-7
1219728-20-7
Chemical Structure
SR7826
- CAS No.: 1219728-20-7
- Formula:C22H21N5O2
- Molecular Weight:387.43
IUPAC Name: 1-(2-hydroxyethyl)-3-(4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)-1-phenylurea
InChIKey: WQAGVQVBDHOHRD-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C2=C3C(NC=C3C)=NC=N2)C=C1)N(CCO)C4=CC=CC=C4
Biological Activity: SR7826 is a class of bis-aryl urea derived potent, selective and orally active LIM kinase (LIMK) inhibitor with an IC50 of 43 nM for LIMK1. SR7826 is >100-fold more selective for LIMK1 than ROCK and JNK kinases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SR7826 | 99.30% | SR7826 is a class of bis-aryl urea derived potent, selective and orally active LIM kinase (LIMK) inhibitor with an IC50 of 43 nM for LIMK1. SR7826 is >100-fold more selective for LIMK1 than ROCK and JNK kinases. | ||||||||||||||||||||
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References
Keywords
