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Results for "

LTA

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Aminopeptidase (20) Autophagy (1) Bacterial (9) Biochemical Assay Reagents (2) Calcium Channel (2) Cathepsin (1) Drug Derivative (1) Endogenous Metabolite (3) HDAC (2) Interleukin Related (1) Isotope-Labeled Compounds (1) Leukotriene Receptor (3) mRNA (1) NO Synthase (2) Opioid Receptor (1) p38 MAPK (1) Raf (1) Reactive Oxygen Species (ROS) (1) Reference Standards (4) Small Interfering RNA (siRNA) (6)
By Research Areas:	Cancer (3) Cardiovascular Disease (2) Infection (10) Inflammation/Immunology (30) Metabolic Disease (2) Neurological Disease (4)
Oligonucleotides:	Rat Pre-designed siRNA Sets (2) mRNA (1) Mouse Pre-designed siRNA Sets (2) Human Pre-designed siRNA Sets (2) siRNAs (6)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0494

Bufexamac 2 Publications Verification Bufexamic acid	HDAC Aminopeptidase	Inflammation/Immunology Cancer
Bufexamac is a selective Ⅱb HDAC (HDAC6, HDAC10) and *LTA4H* dual inhibitor, with K_ds of 0.53 µM and 0.22 µM for HDAC6 and HDAC10. Bufexamac is a nonsteroida anti-inflammatory drug .

HY-W074890

Palmitoylglycine 1 Publications Verification N-palmitoyl glycine	Calcium Channel NO Synthase	Neurological Disease Inflammation/Immunology
Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA .

HY-137298

LYS006 LTA4H-IN-1	Aminopeptidase	Inflammation/Immunology
LTA4H-IN-1 is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) extracted from patent WO2015092740A1, example 29, has an IC₅₀ of 2 nM. LTA4H-IN-1 can be used for the research of inflammatory and autoimmune disorders .

HY-W004291

Methyl arachidate Methyl icosanoate	Aminopeptidase	Infection
Methyl arachidate (Methyl icosanoate) is a component of lipid mixtures. Methyl arachidate can be isolated from flowering plants. Methyl arachidate inhibits *LTA4H. Methyl arachidate shows no antifeedant activity against Leptinotarsa decemlineata* .

HY-P1116

PBP10 1 Publications Verification	Bacterial Reactive Oxygen Species (ROS) Interleukin Related	Infection Inflammation/Immunology
PBP10 is a decapeptide. PBP10 selectively binds to lipoteichoic acid (LTA), lipopolysaccharide (LPS) and phosphatidylinositol-4,5-bisphosphate (PIP₂). PBP10 penetrates cell membranes and possesses bactericidal, anti-inflammatory, cell motility-inhibiting and actin assembly-regulating activities. PBP10 is applicable to relevant research on bacterial infections, microbe-induced inflammation, skin and soft tissue infections, as well as sepsis .

HY-P5255

Oligopeptide-10	Bacterial	Infection Inflammation/Immunology
Oligopeptide-10 is a bioactive peptide with antimicrobial activity. Oligopeptide-10 exhibits broad-spectrum bactericidal effects against Gram-positive bacteria including Propionibacterium acnes and Staphylococcus aureus. Oligopeptide-10 targets lipoteichoic acid (LTA) on the surface of bacterial cell membranes, induces bacterial osmotic imbalance by disrupting the integrity of bacterial membranes, and reduces the release of pro-inflammatory cytokines induced by bacteria. Oligopeptide-10 possesses skin-protective activity. Oligopeptide-10 can be applied in research related to acne vulgaris, dandruff, seborrheic dermatitis, and tinea pedis .

HY-135813

LtaS-IN-1 1 Publications Verification	Bacterial	Infection
LtaS-IN-1 (compound 1771) is a potent small-molecule inhibitor of *Lipoteichoic acid (LTA) synthesis* in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 alone inhibits Enterococcus.spp 28 strains with varying MIC values ranging from 0.5 μg/mL to 64 μg/mL. LtaS-IN-1 combination with antibiotics abolishs multidrug-resistant E. faecium growth almost completely .

HY-10320A

Doramapimod hydrochloride Maximum Cited Publications 51 Publications Verification BIRB 796 hydrochloride	Autophagy Raf p38 MAPK	Inflammation/Immunology
Doramapimod hydrochloride (BIRB 796 hydrochloride) is an anti-inflammatory compound with biological activity through inhibition of p38 MAPK. Doramapimod hydrochloride can significantly inhibit the activities of TNF-α and IL-1β induced by LPS, LTA and PGN. Doramapimod hydrochloride showed a stronger inhibitory effect on inflammation induced by all three bacterial toxins, which was more significant compared with the effects of other compounds. Doramapimod hydrochloride can be used in the research of autoimmune diseases .

HY-103226

SC-57461A 2 Publications Verification	Aminopeptidase	Inflammation/Immunology
SC-57461A is a potent, orally active, nonpeptide, and selective inhibitor of *Leukotriene A4 (LTA4) hydrolase* with IC₅₀s of 2.5 nM, 3 nM, and 23 nM for recombinant human, mouse, and rat LTA4 hydrolase, respectively .

HY-P99309

Pagibaximab BSYX-A 110; Anti-S. Epidermidis LTA Recombinant Antibody	Bacterial	Infection
Pagibaximab is a chimeric IgG1 antibody recognizing the surface component lipoteichoic acid of S. aureus and S. epidermidis. Pagibaximab can be used to prevent staphylococcal sepsis .

HY-P1116A

PBP10 TFA 1 Publications Verification	Bacterial	Infection Inflammation/Immunology
PBP10 TFA is a decapeptide. PBP10 TFA selectively binds to lipoteichoic acid (LTA), lipopolysaccharide (LPS) and phosphatidylinositol-4,5-bisphosphate (PIP₂). PBP10 TFA penetrates cell membranes and possesses bactericidal, anti-inflammatory, cell motility-inhibiting and actin assembly-regulating activities. PBP10 TFA is applicable to relevant research on bacterial infections, microbe-induced inflammation, skin and soft tissue infections, as well as sepsis .

HY-129461

Dibenzyl trisulfide DTS	Cathepsin	Cancer
Dibenzyl trisulfide (DTS) is an active ingredient that can be isolated from Petiveria alliacea L.. Dibenzyl trisulfide inhibits cell proliferation and migration. Dibenzyl trisulfide decreased the mRNA and protein expression of BAK-1 and LTA. Dibenzyl trisulfide induces lysosomal membrane permeabilization and cathepsin B release .

HY-W097753

4-MDM 4-Methoxydiphenylmethane	Aminopeptidase	Others
4-MDM (4-Methoxydiphenylmethane) is an orally active anti-inflammatory compound that selectively enhances the Leukotriene A₄ Hydrolase (LTA₄H) aminopeptidase enzyme activity. 4-MDM reduces the neutrophil recruitment in the lung by enhancing the degradation of proline-glycine-proline by *LTA₄H, thereby reducing inflammation, and does not affect the epoxy-hydrolase activity of LTA₄H*. 4-MDM can be used for research on lung diseases .

HY-N8760

Batatasin IV	Aminopeptidase	Inflammation/Immunology
Batatasin IV is an *LTA4H* inhibitor with anti-inflammatory activity. Batatasin IV is also a natural product that can be obtained from Dioscorea batatus. Batatasin IV can be used in research in the area of inflammation .

HY-113446S

Leukotriene C4-d5	Endogenous Metabolite Isotope-Labeled Compounds	Cardiovascular Disease Inflammation/Immunology
Leukotriene C4-d₅ is the deuterium labeled Leukotriene C4. Leukotriene C4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4.

HY-112621

Leukotriene A4 methyl ester LTA4 methyl ester	Biochemical Assay Reagents	Inflammation/Immunology
Leukotriene A4 methyl ester (LTA4 methyl ester) is synthesized in mast cells, eosinophils, and neutrophils from arachidonic acid by 5-lipoxygenase (5-LO), which exhibits both lipoxygenase and LTA4 synthase activities. LTA4 is rapidly metabolized by LTA4 hydrolase or LTC4 synthase to LTB4 or LTC4, respectively. LTA4, from leukocytes, is known to undergo transcellular metabolism in platelets, erythrocytes, and endothelial cells. Further metabolism of LTA4 by 15-LO leads to lipoxin biosynthesis. LTA4 as a free acid is highly unstable. The methyl ester is stable and can be readily hydrolyzed to the free acid as needed.

HY-W074890R

Palmitoylglycine (Standard) N-palmitoyl glycine (Standard)	Reference Standards Calcium Channel NO Synthase	Neurological Disease Inflammation/Immunology
Palmitoylglycine (Standard) is the analytical standard of Palmitoylglycine. This product is intended for research and analytical applications. Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA[1][2][3].

HY-RS07869

Lta Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Lta Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lta gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Lta Mouse Pre-designed siRNA Set A Lta Mouse Pre-designed siRNA Set A

HY-10828

SC-57461	Aminopeptidase	Inflammation/Immunology
SC-57461 is a potent, orally active, nonpeptide, and selective inhibitor of *Leukotriene A4 (LTA4) hydrolase* with IC₅₀s of 2.5 nM, 3 nM, and 23 nM for recombinant human, mouse, and rat LTA4 hydrolase, respectively .

HY-164051

1650-M15 1 Publications Verification	Bacterial	Infection
1650-M15 is an inhibitor of lipoteichoic acid synthase (LtaS). It has inhibitory activity against Gram-positive bacteria but has no significant inhibitory effect against Gram-negative bacteria. The IC₅₀s of 1650-M15 against MRSA and MSSA are 62.44 μM and 66.42 μM, respectively, and the MICs are both 200 μM .

HY-146811

HSGN-94	Bacterial	Inflammation/Immunology
HSGN-94 is a potent antimicrobial agent with lipoteichoic acid (LTA) biosynthesis inhibition. HSGN-94 inhibits drug-resistant Gram-positive bacteria with MIC values of 0.25-2 μg/mL. HSGN-94 inhibits biofilm formation of MRSA and Vancomycin-resistant Enterococci. HSGN-94 also inhibits pro-inflammatory cytokines, exhibits in vivo efficacy in an MRSA murine wound infection model .

HY-161349

LTA4H-IN-4	Aminopeptidase	Inflammation/Immunology
LTA4H-IN-4 (compound 3) is an orally active *LTA4H* inhibitor. The IC₅₀ value of LTA4H-IN-4 for hERG is 156 μM. LTA4H-IN-4 can be used in inflammation related studies .

HY-115500

PL265	Endogenous Metabolite Opioid Receptor Leukotriene Receptor	Neurological Disease Inflammation/Immunology
PL265 is an orally active dual enkephalinase inhibitor. PL265 is a prodrug of PL254, which can simultaneously and efficiently inhibit neutral endopeptidase (Neprilysin) and Aminopeptidase N. PL265 can effectively protect and significantly increase the local concentration of enkephalins (such as Met-Enkephalin and Leu-Enkephalin) released by cells at the pain or inflammation sites, thereby activating μ and δ opioid receptors to produce a potent analgesic effect. PL254 can also inhibit leukotriene A4 hydrolase (LTA4H), which may contribute to its additional anti-inflammatory effect by reducing the production of pro-inflammatory mediator leukotriene B4 (LTB4). PL265 can be used in non-addictive chronic pain research .

HY-162710

LTA4H-IN-5	Aminopeptidase	Inflammation/Immunology
LTA4H-IN-5 (Compound H122) is an orally active inhibitor for leukotriene A4 hydrolase (LTA4H), that inhibits the LTA4H aminopeptidase and LTA4H hydrolase with IC₅₀ of 0.38 nM and 16.93 nM. LTA4H-IN-5 exhibits good pharmacokinetic characteristics in C57 mice and ameliorates the DNBS-induced ulcerative enteritis in rat models .

HY-160646

LTA4H-IN-3	Aminopeptidase	Inflammation/Immunology
LTA4H-IN-3 (compound 9) is a *LTA4H* inhibitor with the IC₅₀ of 28 nM .

HY-174588

*Human LTA* mRNA**	mRNA	Inflammation/Immunology
Human LTA mRNA encodes the human lymphotoxin alpha (LTA) protein, a member of the tumor necrosis factor family. LTA mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. It involves in the formation of secondary lymphoid organs during development and plays a role in apoptosis.

HY-162015

LTA4H-IN-2	Aminopeptidase	Inflammation/Immunology
LTA4H-IN-2 (compound (S)-2 ) is an orally active inhibitor of Leukotriene A4 Hydrolase, with an IC₅₀ of <3 nM .

HY-156416

LtaS-IN-2	Bacterial	Infection
LtaS-IN-2 (compound 13) is a inhibitor of LTA synthesis, and shows antibacterial activity against S. aureus and S. epidermidis, with the MIC₉₀ of 0.5 μg/mL and 1 μg/mL, respectively. LtaS-IN-2 is a derivative of LtaS-IN-1 (HY-135813) .

HY-RS07870

LTA Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
LTA Rat Pre-designed siRNA Set A contains three designed siRNAs for LTA gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

LTA Rat Pre-designed siRNA Set A LTA Rat Pre-designed siRNA Set A

HY-RS07868

LTA Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
LTA Human Pre-designed siRNA Set A contains three designed siRNAs for LTA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

LTA Human Pre-designed siRNA Set A LTA Human Pre-designed siRNA Set A

HY-RS17060

Lta4h Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Lta4h Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lta4h gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Lta4h Mouse Pre-designed siRNA Set A Lta4h Mouse Pre-designed siRNA Set A

HY-RS23504

Lta4h Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Lta4h Rat Pre-designed siRNA Set A contains three designed siRNAs for Lta4h gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Lta4h Rat Pre-designed siRNA Set A Lta4h Rat Pre-designed siRNA Set A

HY-RS07871

LTA4H Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
LTA4H Human Pre-designed siRNA Set A contains three designed siRNAs for LTA4H gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

LTA4H Human Pre-designed siRNA Set A LTA4H Human Pre-designed siRNA Set A

HY-163336

14,15-Leukotriene A4 methyl ester 14,15-LTA4 methyl ester	Drug Derivative	Inflammation/Immunology
14,15-Leukotriene A4 methyl ester (14,15-LTA4 methyl ester) is the methyl esterified form of Leukotriene A4, which can be used for the study of biological effects of leukotrienes .

HY-130441

Leukotriene B3	Endogenous Metabolite	Inflammation/Immunology
Leukotriene B3 is a LTA hydrolase metabolite of LTA3 in the leukotriene biosynthesis pathway. Leukotriene B3 has proinflammatory activity .

HY-119023

JNJ-26993135	Aminopeptidase	Inflammation/Immunology
JNJ-26993135 is a selective leukotriene A4 hydrolase (LTA4H) inhibitor with the IC₅₀ value of 11 nM .

HY-118795

SC-22716	Aminopeptidase	Inflammation/Immunology
SC-22716 is a potent, competitive, reversible inhibitor of *human LTA₄* hydrolase, with an IC₅₀** of 0.20 µM. SC-22716 has potential for the research of inflammatory bowel disease (IBD) and psoriasis .

HY-137298A

LYS006 hydrochloride	Aminopeptidase	Metabolic Disease Inflammation/Immunology
LYS006 hydrochloride is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) extracted from patent WO2015092740A1, example 29, has an IC₅₀ of 2 nM. LYS006 hydrochloride can be used for the research of inflammatory and autoimmune disorders .

HY-156960

JNJ-40929837	Aminopeptidase Leukotriene Receptor	Inflammation/Immunology
JNJ-40929837 is a selective and orally active *LTA₄H* (leukotriene A₄ hydrolase) inhibitor. JNJ-40929837 effectively inhibits aminopeptidase activity and causes serum accumulation of Pro-Gly-Pro. JNJ-40929837 can be used in asthma research .

HY-156960A

JNJ-40929837 succinate	Aminopeptidase Leukotriene Receptor	Inflammation/Immunology
JNJ-40929837 succinate is a selective and orally active *LTA₄H* (leukotriene A₄ hydrolase) inhibitor. JNJ-40929837 succinate effectively inhibits aminopeptidase activity and causes serum accumulation of Pro-Gly-Pro. JNJ-40929837 succinate can be used in asthma research .

HY-10826

DG051 free acid	Aminopeptidase	Cardiovascular Disease Neurological Disease
DG051 (free acid) is an effective inhibitor of leukotriene A4 hydrolase (LTA4H), with a K_d of 26 nM. It has high water solubility (greater than 30 mg/mL) and high oral bioavailability (over 80% across different species). DG051 (free acid) can be used in research related to myocardial infarction and stroke .

HY-B0494R

Bufexamac (Standard) Bufexamic acid (Standard)	Reference Standards HDAC Aminopeptidase	Inflammation/Immunology Cancer
Bufexamac (Standard) is the analytical standard of Bufexamac. This product is intended for research and analytical applications. Bufexamac is a selective Ⅱb HDAC (HDAC6, HDAC10) and LTA4H dual inhibitor, with Kds of 0.53 μM and 0.22 μM for HDAC6 and HDAC10. Bufexamac is a nonsteroida anti-inflammatory drug .

HY-W004291R

Methyl arachidate (Standard) Methyl icosanoate (Standard)	Reference Standards Aminopeptidase	Infection
Methyl arachidate (Standard) is the analytical standard of Methyl arachidate (HY-W004291). This product is intended for research and analytical applications. Methyl arachidate (Methyl icosanoate) is a component of lipid mixtures. Methyl arachidate can be isolated from flowering plants. Methyl arachidate inhibits *LTA4H. Methyl arachidate shows no antifeedant activity against Leptinotarsa decemlineata* .

HY-149801A

Antibacterial agent 140 chloride	Bacterial	Infection
Antibacterial agent 140 chloride is a promising antibacterial agent. Antibacterial agent 140 chloride is also the first Ru-based AIEgen?photosensitizer?for simultaneous dual applications of?Gram-positive bacteria (G+)?detection. Antibacterial agent 140 chloride uniquely selective discriminates and efficient exterminates Gram-positive bacteria (G+)?from other bacteria due to its interaction with?lipoteichoic acids?(LTA). Antibacterial agent 140 chloride ?also possessed robust?antibacterial activity?for?G+ under?light irradiation .

HY-103226R

SC-57461A (Standard)	Reference Standards Aminopeptidase	Inflammation/Immunology
SC-57461A (Standard) is the analytical standard of SC-57461A (HY-103226). This product is intended for research and analytical applications. SC-57461A is a potent, orally active, nonpeptide, and selective inhibitor of Leukotriene A4 (LTA4) hydrolase with IC₅₀s of 2.5 nM, 3 nM, and 23 nM for recombinant human, mouse, and rat LTA4 hydrolase, respectively .

HY-W004291S

Methyl arachidate-d39 Methyl icosanoate-d₃₉	Biochemical Assay Reagents	Metabolic Disease
Methyl arachidate-d39 is the deuterated Methyl arachidate. Methyl arachidate, a natural compound, is a?leukotriene A4 hydrolase?(LTA4H)?inhibitor

HY-160541

Mal-PEG2000-NHS ester	ADC Linker	Inflammation/Immunology
Mal-PEG2000-NHS ester is a PEG linker, can be used to link lipoteichoic acid (LTA) and CpG DNA fragments to synthesis CpG-TA Heterodiners. Mal-PEG2000-NHS ester can be used for immune stimulation research .

Cat. No.	Product Name	Target	Research Area

HY-P1116

PBP10 1 Publications Verification	Bacterial Reactive Oxygen Species (ROS) Interleukin Related	Infection Inflammation/Immunology
PBP10 is a decapeptide. PBP10 selectively binds to lipoteichoic acid (LTA), lipopolysaccharide (LPS) and phosphatidylinositol-4,5-bisphosphate (PIP₂). PBP10 penetrates cell membranes and possesses bactericidal, anti-inflammatory, cell motility-inhibiting and actin assembly-regulating activities. PBP10 is applicable to relevant research on bacterial infections, microbe-induced inflammation, skin and soft tissue infections, as well as sepsis .

HY-P5255

Oligopeptide-10	Bacterial	Infection Inflammation/Immunology
Oligopeptide-10 is a bioactive peptide with antimicrobial activity. Oligopeptide-10 exhibits broad-spectrum bactericidal effects against Gram-positive bacteria including Propionibacterium acnes and Staphylococcus aureus. Oligopeptide-10 targets lipoteichoic acid (LTA) on the surface of bacterial cell membranes, induces bacterial osmotic imbalance by disrupting the integrity of bacterial membranes, and reduces the release of pro-inflammatory cytokines induced by bacteria. Oligopeptide-10 possesses skin-protective activity. Oligopeptide-10 can be applied in research related to acne vulgaris, dandruff, seborrheic dermatitis, and tinea pedis .

HY-P1116A

PBP10 TFA 1 Publications Verification	Bacterial	Infection Inflammation/Immunology
PBP10 TFA is a decapeptide. PBP10 TFA selectively binds to lipoteichoic acid (LTA), lipopolysaccharide (LPS) and phosphatidylinositol-4,5-bisphosphate (PIP₂). PBP10 TFA penetrates cell membranes and possesses bactericidal, anti-inflammatory, cell motility-inhibiting and actin assembly-regulating activities. PBP10 TFA is applicable to relevant research on bacterial infections, microbe-induced inflammation, skin and soft tissue infections, as well as sepsis .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99309

Pagibaximab BSYX-A 110; Anti-S. Epidermidis LTA Recombinant Antibody	Bacterial	Infection
Pagibaximab is a chimeric IgG1 antibody recognizing the surface component lipoteichoic acid of S. aureus and S. epidermidis. Pagibaximab can be used to prevent staphylococcal sepsis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W074890

Palmitoylglycine 1 Publications Verification N-palmitoyl glycine	Human Gut Microbiota Metabolites Microorganisms Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Calcium Channel NO Synthase
Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA .

HY-W004291

Methyl arachidate Methyl icosanoate	Structural Classification Natural Products other families Classification of Application Fields Plants Inflammation/Immunology Disease Research Fields Source Classification	Aminopeptidase
Methyl arachidate (Methyl icosanoate) is a component of lipid mixtures. Methyl arachidate can be isolated from flowering plants. Methyl arachidate inhibits *LTA4H. Methyl arachidate shows no antifeedant activity against Leptinotarsa decemlineata* .

HY-129461

Dibenzyl trisulfide DTS	Natural Products Petiveriaceae Plants Petiveria alliacea Source Classification	Cathepsin
Dibenzyl trisulfide (DTS) is an active ingredient that can be isolated from Petiveria alliacea L.. Dibenzyl trisulfide inhibits cell proliferation and migration. Dibenzyl trisulfide decreased the mRNA and protein expression of BAK-1 and LTA. Dibenzyl trisulfide induces lysosomal membrane permeabilization and cathepsin B release .

HY-N8760

Batatasin IV	Leguminosae Phenols Polyphenols Plants Bauhinia purpurea L. Source Classification	Aminopeptidase
Batatasin IV is an *LTA4H* inhibitor with anti-inflammatory activity. Batatasin IV is also a natural product that can be obtained from Dioscorea batatus. Batatasin IV can be used in research in the area of inflammation .

HY-W074890R

Palmitoylglycine (Standard) N-palmitoyl glycine (Standard)	Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Calcium Channel NO Synthase
Palmitoylglycine (Standard) is the analytical standard of Palmitoylglycine. This product is intended for research and analytical applications. Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA[1][2][3].

HY-130441

Leukotriene B3	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite
Leukotriene B3 is a LTA hydrolase metabolite of LTA3 in the leukotriene biosynthesis pathway. Leukotriene B3 has proinflammatory activity .

HY-W004291R

Methyl arachidate (Standard) Methyl icosanoate (Standard)	Structural Classification Natural Products other families Classification of Application Fields Plants Inflammation/Immunology Disease Research Fields Source Classification	Reference Standards Aminopeptidase
Methyl arachidate (Standard) is the analytical standard of Methyl arachidate (HY-W004291). This product is intended for research and analytical applications. Methyl arachidate (Methyl icosanoate) is a component of lipid mixtures. Methyl arachidate can be isolated from flowering plants. Methyl arachidate inhibits *LTA4H. Methyl arachidate shows no antifeedant activity against Leptinotarsa decemlineata* .

Species:	Human (7) Mouse (2)
Tag:	His (7) Tag Free (1) Avi (1) Fc (1)
Source:	HEK293 (4) Sf9 insect cells (2) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P704408

	TNF-beta/TNFSF1 Protein, Human (144a.a, HEK293, hFc) Lymphotoxin-Alpha; LT-Alpha; TNF-beta; Tumor Necrosis Factor Ligand Superfamily Member 1; LTA; TNFB; TNFSF1	Human	HEK293
	TNF-β protein acts as a homotrimeric cytokine that binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR, and TNFRSF14/HVEM. TNF-beta/TNFSF1 Protein, Human (144a.a, HEK293, hFc) is the recombinant human-derived TNF-beta/TNFSF1 protein, expressed by HEK293, with N-hFc labeled tag.

HY-P700154AF

	Animal-Free TNF-beta/TNFSF1 Protein, Human (His) Lymphotoxin-Alpha; LT-Alpha; TNF-beta; Tumor Necrosis Factor Ligand Superfamily Member 1; LTA; TNFB; TNFSF1	Human	E. coli
	TNF-β protein acts as a homotrimeric cytokine that binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR, and TNFRSF14/HVEM. Animal-Free TNF-beta/TNFSF1 Protein, Human (His) is the recombinant human-derived animal-FreeTNF-beta/TNFSF1 protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.

HY-P70277

	*Leukotriene A4 Hydrolase/LTA4H Protein, Human (HEK293, His)* rHuLeukotriene A-4 hydrolase/LTA4H, His; Leukotriene A-4 hydrolase; LTA-4 hydrolase; Leukotriene A(4) hydrolase; LTA4; LTA4H	Human	HEK293
	The leukotriene A4 hydrolase/LTA4H protein is a bifunctional zinc metalloenzyme that functions as an epoxide hydrolase to convert LTA4 to the proinflammatory mediator LTB4 and exhibits aminopeptidase activity targeting the N-terminal arginine. In addition to its pro-inflammatory effects, LTA4H also combats inflammation by inactivating the neutrophil attractant Pro-Gly-Pro. Leukotriene A4 Hydrolase/LTA4H Protein, Human (HEK293, His) is the recombinant human-derived Leukotriene A4 Hydrolase/LTA4H protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P700419

	TNF-beta/TNFSF1 Protein, Human (HEK293, His) LTA; lymphotoxin alpha (TNF superfamily, member 1); LT; TNFB; TNFSF1; lymphotoxin alpha; OTTHUMP00000165897; tumor necrosis factor beta; Tumor necrosis factor ligand superfamily member 1; TNF-beta; LT-alpha	Human	HEK293
	TNF-β protein acts as a homotrimeric cytokine that binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR, and TNFRSF14/HVEM. TNF-beta/TNFSF1 Protein, Human (HEK293, His) is the recombinant human-derived TNF-beta/TNFSF1 protein, expressed by HEK293 , with N-6*His labeled tag.

HY-P74776

	*Leukotriene A4 Hydrolase/LTA4H Protein, Mouse (sf9, His)* Leukemia inhibitory factor; Leukotriene A-4 hydrolase; LTA-4 hydrolase; LTA4H	Mouse	Sf9 insect cells
	The LTA4H protein is a bifunctional zinc metalloenzyme that acts as an epoxide hydrolase to convert leukotriene A4 (LTA4) into proinflammatory leukotriene B4 (LTB4).It also acts as an aminopeptidase, cleaving N-terminal arginine and fighting inflammation, particularly through Pro-Gly-Pro (PGP) cleavage.Leukotriene A4 Hydrolase/LTA4H Protein, Mouse (sf9, His) is the recombinant mouse-derived Leukotriene A4 Hydrolase/LTA4H protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P73275

	*Leukotriene A4 Hydrolase/LTA4H Protein, Human (sf9, His)* Leukemia inhibitory factor; Leukotriene A-4 hydrolase; LTA-4 hydrolase; LTA4H	Human	Sf9 insect cells
	The leukotriene A4 hydrolase/LTA4H protein is a bifunctional zinc metalloenzyme that functions as an epoxide hydrolase to convert LTA4 to the proinflammatory mediator LTB4 and exhibits aminopeptidase activity targeting the N-terminal arginine. In addition to its pro-inflammatory effects, LTA4H also combats inflammation by inactivating the neutrophil attractant Pro-Gly-Pro. Leukotriene A4 Hydrolase/LTA4H Protein, Human (sf9, His) is the recombinant human-derived Leukotriene A4 Hydrolase/LTA4H protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P700228AF

	Animal-Free TNF-beta/TNFSF1 Protein, Mouse (His) TNFSF1B; Lymphotoxin-alpha (LT-α); LTAlpha; Ltx; TNF-be; TNFSF1; Tnf; Tnfb; Tnfsf; Tnfsf1b; Tnlg1e; hlb38; hlb382; lymph	Mouse	E. coli
	The animal-free TNF beta protein acts as a homotrimeric cytokine that binds TNFRSF1A/TNFR1, TNFRSF1B/TNFBR, and TNFRSF14/HVEM.Animal-Free TNF-beta/TNFSF1 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeTNF beta protein, expressed by E.coli , with N-His labeled tag.This product is for cell culture use only.

HY-P7304

	TNF-beta/TNFSF1 Protein, Human rHuTNF-β; TNF-β; TNFSF1; Lymphotoxin-alpha	Human	E. coli
	TNF-β (tumor necrosis factor β) also called lymphotoxin-α (LT-α), a member of the tumor necrosis factor superfamily, is a cytokine produced by lymphocytes. TNF-β activates the NF-κB signaling pathway, inducing cancer cell proliferation, invasion. TNF-β up-regulates genes connected with metastasis, promotes epithelial-to-mesenchymal-transition, stimulates its own expression. TNF-β mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. TNF-beta/TNFSF1 Protein, Human is a recombinant protein consisting of 158 amino acids (L35-L205) and is produced in E. coli.

HY-P700612

	TNF-beta/TNFSF1 Protein, Human (Biotinylated, HEK293, His-Avi) LTA; lymphotoxin alpha (TNF superfamily, member 1); LT; TNFB; TNFSF1; lymphotoxin alpha; OTTHUMP00000165897; tumor necrosis factor beta; Tumor necrosis factor ligand superfamily member 1; TNF-beta; LT-alpha	Human	HEK293
	TNF-β protein acts as a homotrimeric cytokine that binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR, and TNFRSF14/HVEM. TNF-beta/TNFSF1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived TNF-beta/TNFSF1 protein, expressed by HEK293 , with N-Avi, N-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-113446S

Leukotriene C4-d5
Leukotriene C4-d₅ is the deuterium labeled Leukotriene C4. Leukotriene C4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4.

HY-W004291S

Methyl arachidate-d39
Methyl arachidate-d39 is the deuterated Methyl arachidate. Methyl arachidate, a natural compound, is a?leukotriene A4 hydrolase?(LTA4H)?inhibitor

Host:	Rabbit (2)
Reactivity:	Human (2) Rat (1) Mouse (1)
Application:	IHC-P (1) ICC/IF (1) WB (2) FC (1)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2) Biotin (1)
Clonality:	Monoclonal (2) Recombinant (2)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82655

	Leukotriene A4 Hydrolase Antibody (YA2400) LTA4; LTA4 hydrolase; LTA4H	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	Leukotriene A4 Hydrolase Antibody (YA2400) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Leukotriene A4 Hydrolase.

HY-P83589

	Lymphotoxin alpha Antibody (YA3334) LTAlpha; DIF; LT alpha; LTA; Lymphotoxin alpha; TNF B; TNF superfamily member 1; TNF-beta; TNFB; TNFbeta; TNFSF1; TNLG1E	WB	Human
	Lymphotoxin alpha Antibody (YA3334) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Lymphotoxin alpha.