2441-41-0
2441-41-0
Chemical Structure
Palmitoylglycine
Synonym(s): N-palmitoyl glycine
- CAS No.: 2441-41-0
- Formula:C18H35NO3
- Molecular Weight:313.48
IUPAC Name: palmitoylglycine
InChIKey: KVTFEOAKFFQCCX-UHFFFAOYSA-N
SMILES: O=C(O)CNC(CCCCCCCCCCCCCCC)=O
Biological Activity: Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA[1][2][3].
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Palmitoylglycine | 99.84% | Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA. | ||||||||||||||||||||
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Palmitoylglycine (Standard) | 99.84% | Palmitoylglycine (Standard) is the analytical standard of Palmitoylglycine. This product is intended for research and analytical applications. Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA. | ||||||||||||||||||||
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Palmitoylglycine-d31 | 99.40% | Palmitoylglycine-d31 is the deuterium labeled Palmitoylglycine. | ||||||||||||||||||||
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References
- [1]. Neta Rimmerman, et al. N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Mol Pharmacol. 2008 Jul;74(1):213-24. [Content Brief]
- [2]. Xu H, et al. N-Palmitoyl glycine activates transient receptor potential channel 5 and increases the risk of Brugada syndrome[J]. medRxiv, 2024: 2024.10. 21.24315897.
- [3]. Bradshaw HB, et al. Novel endogenous N-acyl glycines identification and characterization. Vitam Horm. 2009;81:191-205. [Content Brief]
