Cat. No.: HY-113204

N-Oleoyl glycine

2 Cited Publications

Customer Review

Based on 2 publication(s) in Google Scholar

N-Oleoyl glycine is a lipoamino acid, which stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte.

For research use only. We do not sell to patients.

Purity: 99.0%
CAS No.: 2601-90-3
Formula: C₂₀H₃₇NO₃
Molecular Weight:339.51

Storage:

-20°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

N-Oleoyl glycine Chemical Structure

CAS No.: 2601-90-3

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Publications (2)
Solvent & Solubility
- In Vitro
- In Vivo
Purity & Documentation
References
Help & FAQs
Classifications
Bioz

Biological Activity

Description

N-Oleoyl glycine is a lipoamino acid, which stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte.

IC₅₀ & Target^[1]

Human Endogenous Metabolite

CB1

All Endogenous Metabolite Isoforms :

All Cannabinoid Receptor Isoforms :

All Akt Isoforms :

In Vitro

N-Oleoyl glycine is a lipoamino acid, which stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte. N-Oleoyl glycine (1, 5, 10, 20, 50 μM) dose- and time-dependently stimulates 3T3-L1 adipogenesis after treatment for 1-10 days via activation of CB1R. N-Oleoyl glycine also elevates Akt signaling pathway during the differentiation of 3T3-L1 adipocytes^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2601-90-3
Appearance Solid
Molecular Weight 339.51
Formula C₂₀H₃₇NO₃
Color Off-white to light yellow
SMILES

O=C(O)CNC(CCCCCCC/C=C\CCCCCCCC)=O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Endogenous metabolite
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Publications (2)

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Journal Impact Factor

Curr Sci

2025 Oct 5.
Research Square Print

December 21st, 2022.

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (294.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.9454 mL

14.7271 mL

29.4542 mL

5 mM

0.5891 mL

2.9454 mL

5.8908 mL

10 mM

0.2945 mL

1.4727 mL

2.9454 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

Stock Solution Working Solution

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% Corn Oil

Solubility: ≥ 2.5 mg/mL (7.36 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage Dosage
mg/kg
Animal Weight (Per Animal) Animal Weight (Per Animal)
g
Dosing Volume (Per Animal) Dosing Volume (Per Animal)
μL
Number of Animals Number of Animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

%
DMSO +

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
%
+
+
%
Tween-80 + +
%
Saline +

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Working solution concentration: 0.22 mg/mL

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wang S, et al. N-Oleoyl glycine, a lipoamino acid, stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte. Biochem Biophys Res Commun. 2015 Oct 23;466(3):438-43. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.9454 mL	14.7271 mL	29.4542 mL	73.6355 mL
	5 mM	0.5891 mL	2.9454 mL	5.8908 mL	14.7271 mL
	10 mM	0.2945 mL	1.4727 mL	2.9454 mL	7.3636 mL
	15 mM	0.1964 mL	0.9818 mL	1.9636 mL	4.9090 mL
	20 mM	0.1473 mL	0.7364 mL	1.4727 mL	3.6818 mL
	25 mM	0.1178 mL	0.5891 mL	1.1782 mL	2.9454 mL
	30 mM	0.0982 mL	0.4909 mL	0.9818 mL	2.4545 mL
	40 mM	0.0736 mL	0.3682 mL	0.7364 mL	1.8409 mL
	50 mM	0.0589 mL	0.2945 mL	0.5891 mL	1.4727 mL
	60 mM	0.0491 mL	0.2455 mL	0.4909 mL	1.2273 mL
	80 mM	0.0368 mL	0.1841 mL	0.3682 mL	0.9204 mL
	100 mM	0.0295 mL	0.1473 mL	0.2945 mL	0.7364 mL

Keywords

N-Oleoyl glycine

2 Cited Publications

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N-Oleoyl glycine

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Publications Citing Use of MedChemExpress (MCE) N-Oleoyl glycine

All Endogenous Metabolite Isoforms

All Cannabinoid Receptor Isoforms

All Akt Isoforms

Biological Activity

Chemical Information

Publications (2)

Solvent & Solubility

Purity & Documentation

References

Help & FAQs

Complete Stock Solution Preparation Table

N-Oleoyl glycine Related Classifications

HY-113204 Related Classifications