877950-01-1
Chemical Structure
LtaS-IN-1
- CAS No.: 877950-01-1
- Formula:C24H17N3O5
- Molecular Weight:427.41
IUPAC Name: 2-oxo-2-((5-phenyl-1,3,4-oxadiazol-2-yl)amino)ethyl 2-(naphtho[2,1-b]furan-1-yl)acetate
InChIKey: KNJXREYSQNBQEX-UHFFFAOYSA-N
SMILES: O=C(OCC(NC1=NN=C(C2=CC=CC=C2)O1)=O)CC3=COC4=CC=C5C=CC=CC5=C43
Biological Activity: LtaS-IN-1 (compound 1771) is a potent small-molecule inhibitor of Lipoteichoic acid (LTA) synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 alone inhibits Enterococcus.spp 28 strains with varying MIC values ranging from 0.5 μg/mL to 64 μg/mL. LtaS-IN-1 combination with antibiotics abolishs multidrug-resistant E. faecium growth almost completely[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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LtaS-IN-1 | 99.58% | LtaS-IN-1 (compound 1771) is a potent small-molecule inhibitor of Lipoteichoic acid (LTA) synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 alone inhibits Enterococcus.spp 28 strains with varying MIC values ranging from 0.5 μg/mL to 64 μg/mL. LtaS-IN-1 combination with antibiotics abolishs multidrug-resistant E. faecium growth almost completely. | ||||||||||||||||||||
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Similarity Score 0.53
HY-103692RSTX-0119 (Standard) -
Similarity Score 0.51
HY-162717GPX4-IN-11 -
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HY-1693652-Methylbiphenyl-oxadiazole-NH-Ph-CHO -
Similarity Score 0.48
HY-144258PD-1/PD-L1-IN-14 -
Similarity Score 0.48
HY-155190Antitubercular agent-39 -
Similarity Score 0.48
HY-148305PD-1/PD-L1-IN-28 -
Similarity Score 0.47
HY-590212-(4-Biphenylyl)-5-phenyl-1,3,4-oxadiazole -
Similarity Score 0.47
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