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Cat. No.: HY-162717

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GPX4-IN-11

GPX4-IN-11 (compound I14) is a potent inhibitor of GPX4, with the K_D of 45.7 μM. GPX4-IN-11 plays an important role in ferroptosis research.

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CAS No.: 951570-56-2
Formule: C₂₇H₂₆N₄O₄
Masse moléculaire:470.52

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

GPX4-IN-11 Chemical Structure

CAS No.: 951570-56-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

GPX4-IN-11 (compound I14) is a potent inhibitor of GPX4, with the K_D of 45.7 μM. GPX4-IN-11 plays an important role in ferroptosis research^[1].

IC₅₀ & Target

GPX4

Voir tous les produits spécifiques à Isoform Glutathione Peroxidase :

GPX1
GPX4

Chemical Information

CAS No. 951570-56-2
Masse moléculaire 470.52
Formule C₂₇H₂₆N₄O₄
SMILES

O=C(COC1=CC=CC=C1C2=NN=C(C3=CC=CC=C3)O2)NC(C=C4)=CC=C4CN5CCOCC5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Wei Huang, et al. Ferroptosis-inducing compounds synergize with docetaxel to overcome chemoresistance in docetaxel-resistant non-small cell lung cancer cells. Eur J Med Chem. 2024 Jul 10:276:116670. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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GPX4-IN-11

Voir tous les produits spécifiques à Isoform Glutathione Peroxidase