2 Results for "

LY108742

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "LY108742" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-116606
CAS No.: 150196-69-3
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

LY108742 is a 5-HT2 receptor antagonist, with IC50 values of 9.3 nM (Rat), 57.2 nM (Pig), 56.8 nM (Monkey) .
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Cat. No.: HY-123567
CAS No.: 148966-66-9
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

LY86057 is an ergoline derivative without N1 substituents. It has higher affinity for porcine, squirrel monkey and human 5-HT2 receptors than rats and is an antagonist of 5-HT2 receptors. When studying the differences in recognition of a series of ergolines between species, LY86057 was found to be more selective for 5-HT2 receptors. Compared with LY53857, LY108742 resulted in a higher affinity for rat 5-HT2 receptors even when the N1 substituent was only methyl.
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