1 Result for "

LY2811376 (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LY2811376 (Standard)" in MCE Product Catalog:

Cat. No.: HY-10472R
CAS No.: 1194044-20-6
Research Areas:  

Neurological Disease

LY2811376 (Standard) is the analytical standard of LY2811376 (HY-10472). This product is intended for research and analytical applications. LY2811376 is the first orally available non-peptidic β-secretase (BACE1) inhibitor with IC50 of 239 nM-249 nM, that acts to decrease Aβ secretion with EC50 of 300 nM, and demonstrates to have 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition over other aspartic proteases including cathepsin D, pepsin, or renin.
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