3 Results for "

Lenalidomide-PEG1-azide

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Lenalidomide-PEG1-azide" in MCE Product Catalog:

Cat. No.: HY-133139
CAS No.: 2185795-67-7
Purity:  95.84%
Research Areas:  

Cancer

Lenalidomide-PEG1-azide is a cereblon (CRBN)-recruiting azide-functionalized Lenalidomide (HY-A0003) derivative with a PEG1 linker, serving as a building block for synthesis of soluble epoxide hydrolase (sEH) PROTACs [1].Lenalidomide-PEG1-azide lacks definitive identity or significant scientific classification in associated literature.
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1
1 Cited Publications
Cat. No.: HY-P10899
Target:  

PROTACs TGF-beta/Smad

Research Areas:  

Endocrinology

ETTAC-2 is a LRG1 PROTAC degrader, degrading LRG1 via the ubiquitin-proteasome pathway with a DC50 value of 8.38 μM. ETTAC-2 penetrates damaged renal cells to reduce the extracellular secretion of LRG1. ETTAC-2 effectively inhibits the TGF-β-Smad3 signaling pathway and diminishes the secretion of fibrosis-associated extracellular matrix proteins. ETTAC-2 degrades LRG1 within fibrotic kidneys and the efficacy in inhibiting the TGF-β-Smad3 pathway both in vitro and vivo. ETTAC-2 can be used for renal fibrosis research [1].
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Cat. No.: HY-P10303
CAS No.: 2767993-86-0
Synonyms: Cyclo[RGDfK(azide)]
Research Areas:  

Others

Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] is the derivative of Cyclo(-RGDfK) (HY-P0023). Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity [1].
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