Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
43 Results for "
Low membrane permeability
" in MedChemExpress (MCE) Product Catalog:
Products (43)
43 Results for "Low membrane permeability" in MCE Product Catalog:
85
85 Publications Verification
Cat. No.: HY-D0985A
CAS No.: 115532-52-0
Synonyms: Tetramethylrhodamine ethyl ester perchlorate
42
29
4
1
1 Cited Publications
Cat. No.: HY-D1694
CAS No.: 1064123-31-4
Cat. No.: HY-D0984
CAS No.: 115532-49-5
Cat. No.: HY-DY1042
CAS No.: 115532-50-8
Solvent and concentration: DMSO: 10 mM
Cat. No.: HY-DY1023
CAS No.: 115532-52-0
Solvent and concentration: DMSO: 10 mM
Cat. No.: HY-DY1054
CAS No.: 62669-70-9
Solvent and concentration: DMSO: 5 mM
Cat. No.: HY-P5107
CAS No.: 121052-30-0
Synonyms: LMWP; TDSP5
MA220607 is a FtsZ protein inhibitor with activity against both Gram-positive and Gram-negative bacteria. MA220607 inhibits bacterial growth and shows low bacterial resistance frequency. MA220607 increases bacterial membrane permeability and alters proton gradients. MA220607 blocks the formation of bacterial biofilms. MA220607 can be used in studies of bacterial infections .
Cat. No.: HY-149431
Target:
Research Areas:
NDNA4 (compound 17) is a selective inhibitor of Hsp90α (IC50: 0.34 μM). NDNA4 is a permanently charged analog with low membrane permeability and low cytotoxicity against Ovcar-8 and MCF-10A ((IC50 >100 μM)). NDNA4 prevents disruption of hERG channel maturation without generating a heat shock response or causing degradation of Hsp90α-dependent client proteins .
Cat. No.: HY-W127780
CAS No.: 13161-28-9
Synonyms: Basic Red 1 perchlorate
Cat. No.: HY-146341
CAS No.: 1338575-38-4
Research Areas:
FAAH-IN-5 (Compound 7) is a relative selective, irreversible fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 10.5 nM. FAAH-IN-5 shows low PAMPA (Parallel Artificial Membrane Permeability Assay) permeability .
Cat. No.: HY-19405
CAS No.: 178309-91-6
Target:
Research Areas:
UK-224671 is a potent and selective NK2 receptor antagonist. UK-224671 is affected by P-gp efflux and poor intrinsic membrane permeability, resulting in low oral bioavailability .
Cat. No.: HY-146342
CAS No.: 2848719-34-4
Research Areas:
FAAH/MAGL-IN-3 (Compound 10) is an irreversible fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) dual inhibitor with IC50 values of 179 and 759 nM against FAAH and MAGL, respectively. FAAH/MAGL-IN-3 shows low PAMPA (Parallel Artificial Membrane Permeability Assay) permeability .
Cat. No.: HY-145257
CAS No.: 1808389-92-5
Target:
Research Areas:
GABAA receptor agent 5 (compound 018) is a potent γ-GABAAR antagonist with an Ki of 0.020 µM. GABAA receptor agent 5 shows γ-GABAAR antagonist activity with low cellular membrane permeability .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
