178309-91-6
178309-91-6
Chemical Structure
UK-224671
- CAS No.: 178309-91-6
- Formula:C25H36Cl2N4O3S
- Molecular Weight:543.55
IUPAC Name: (S)-1-(cyclopropylmethyl)-5-(3,4-dichlorophenyl)-5-(2-(3-(4-(methylsulfonyl)piperazin-1-yl)azetidin-1-yl)ethyl)piperidin-2-one
InChIKey: YZMQJVWDZXNEBA-RUZDIDTESA-N
SMILES: O=S(N1CCN(C2CN(CC[C@@](CC3)(C4=CC=C(Cl)C(Cl)=C4)CN(CC5CC5)C3=O)C2)CC1)(C)=O
Biological Activity: UK-224671 is a potent and selective NK2 receptor antagonist. UK-224671 is affected by P-gp efflux and poor intrinsic membrane permeability, resulting in low oral bioavailability[1].
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UK-224671 | UK-224671 is a potent and selective NK2 receptor antagonist. UK-224671 is affected by P-gp efflux and poor intrinsic membrane permeability, resulting in low oral bioavailability. | |||||||||||||||||||||
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