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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
Lp (a)
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "Lp (a)" in MCE Product Catalog:
Synonyms: LY3473329
Target:
Research Areas:
Muvalaplin (LY3473329) is an orally active, selective small molecule inhibitor of lipoprotein (a) (Lp (a)) that disrupts the initial non-covalent interaction between apo(a) and apoB100, preventing the disulphide bond and Lp(a)
formation. Muvalaplin reduces the levels of Lp (a) in transgenic mice and in cynomolgus monkeys .
Cat. No.: HY-171464
CAS No.: 2924841-79-0
Target:
Research Areas:
Lp(a)-IN-5 (Compound A) is an orally active lipoprotein (a) (Lp(a)) inhibitor. Lp(a)-IN-5 inhibits the assembly of Apo(a) and ApoB proteins with an IC50 value of 0.41 nM. Lp(a)-IN-5 is promising for research of diseases related to elevated plasma Lp(a) levels, such as cardiovascular diseases .
Cat. No.: HY-171464A
CAS No.: 2924841-80-3
Target:
Research Areas:
Lp(a)-IN-5 (Compound A) hydrochloride is an orally active lipoprotein (a) (Lp(a)) inhibitor. Lp(a)-IN-5 hydrochloride inhibits the assembly of Apo(a) and ApoB proteins with an IC50 value of 0.41 nM. Lp(a)-IN-5 hydrochloride is promising for research of diseases related to elevated plasma Lp(a) levels, such as cardiovascular diseases .
Cat. No.: HY-173323
CAS No.: 3070232-49-1
Target:
Research Areas:
Lp(a)-IN-7 (example 1) is a lipoprotein (a) (Lp(a)) formation inhibitor with an IC50 of 2.51 nM in conditioned media containing apolipoprotein B (apoB) and apolipoprotein(a). Lp(a)-IN-7 can be used for the study of cardiovascular disease .
Cat. No.: HY-171465
CAS No.: 2566425-77-0
Target:
Research Areas:
Lp(a)-IN-6 (Compound 6) is a lipoprotein(a) (Lp(a)) inhibitor, with an IC50 of <0.314 nM. Lp(a)-IN-6 can be used for the research of cardiovascular disease (CVD) .
Cat. No.: HY-173322
CAS No.: 3070206-18-4
Target:
Research Areas:
Lp(a)-IN-8 is a Lp(a) assembly inhibitor with an IC50 of 0.749 nM. Lp(a)-IN-8 can be used in studies related to cardiovascular diseases and elevated plasma Lp(a) levels .
Cat. No.: HY-P77066
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LpAL2; Apolipoprotein A-Related Gene C Protein; Prev. APOAL; Lipoprotein, Lp(a)-Like 2; APOARGC; Apolipoprotein A-Like; Lipoprotein, Lp(a)-Like 2, Pseudogene; Lp(a)-Liker Protein 2; Apo(a)Rg-C; Apo(a)-Like Protein 2; Putative Apolipoprotein(a)-Like Protei
Species:
Human
Source:
HEK293
Cat. No.: HY-P70993
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLA2G7; LDL-Associated Phospholipase A2; Phospholipase A2 Group VII; Group-VIIA Phospholipase A2; PAFAH; PAF 2-Acylhydrolase; LDL-PLA2; PAF Acetylhydrolase; Lp-PLA2; LDL-PLA(2); Phospholipase A2, Group VII (Platelet-Activating Factor Acetylhydrolase, Plas
Species:
Human
Source:
HEK293
Cat. No.: HY-P77444
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLA2G7; LDL-Associated Phospholipase A2; Phospholipase A2 Group VII; Group-VIIA Phospholipase A2; PAFAH; PAF 2-Acylhydrolase; LDL-PLA2; PAF Acetylhydrolase; Lp-PLA2; LDL-PLA(2); Phospholipase A2, Group VII (Platelet-Activating Factor Acetylhydrolase, Plas
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P700567
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLA2G7; LDL-Associated Phospholipase A2; Phospholipase A2 Group VII; Group-VIIA Phospholipase A2; PAFAH; PAF 2-Acylhydrolase; LDL-PLA2; PAF Acetylhydrolase; Lp-PLA2; LDL-PLA(2); Phospholipase A2, Group VII (Platelet-Activating Factor Acetylhydrolase, Plas
Species:
Mouse
Source:
Sf9 insect cells
Cat. No.: HY-P700568
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLA2G7; LDL-Associated Phospholipase A2; Phospholipase A2 Group VII; Group-VIIA Phospholipase A2; PAFAH; PAF 2-Acylhydrolase; LDL-PLA2; PAF Acetylhydrolase; Lp-PLA2; LDL-PLA(2); Phospholipase A2, Group VII (Platelet-Activating Factor Acetylhydrolase, Plas
Species:
Mouse
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
