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Cat. No.: HY-173322

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Lp(a)-IN-8

Lp(a)-IN-8 is a Lp(a) assembly inhibitor with an IC₅₀ of 0.749 nM. Lp(a)-IN-8 can be used in studies related to cardiovascular diseases and elevated plasma Lp(a) levels.

For research use only. We do not sell to patients.

CAS No.: 3070206-18-4
Formula: C₂₁H₄₀Cl₂N₄O₅
Molecular Weight:499.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Lp(a)-IN-8 Chemical Structure

CAS No.: 3070206-18-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Lp(a)-IN-8 is a Lp(a) assembly inhibitor with an IC₅₀ of 0.749 nM. Lp(a)-IN-8 can be used in studies related to cardiovascular diseases and elevated plasma Lp(a) levels^[1].

All Apolipoprotein Isoforms :

In Vitro

Lp(a)-IN-8 (Compound 15) (0.01-100 nM; 2 h) inhibits the assembly of Lp(a) particles from ApoB and Apo(a) in a cell-free in vitro assay with an IC₅₀ of 0.749 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3070206-18-4
Molecular Weight 499.47
Formula C₂₁H₄₀Cl₂N₄O₅
SMILES

O=C(O)[C@@H](CCCCNC(NCCCC[C@H](C(O)=O)[C@@H]1CNCC1)=O)[C@H]2CCNC2.Cl.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Carlos LAMAS PETEIRA, et al. Pyrrolidine Compounds with Lp(a) Lowering Activity. WO2025024218A1. WIPO (PCT). 2024-07-18.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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- In Vitro
Chemical Information
Purity & Documentation
References

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Lp(a)-IN-8

All Apolipoprotein Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Lp(a)-IN-8 Related Classifications

HY-173322 Related Classifications