5 Results for "

MAPK-IN-6

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "MAPK-IN-6" in MCE Product Catalog:

Cat. No.: HY-180807
MAPK-IN-6 is a blood-brain barrier-permeable MAPK inhibitor. MAPK-IN-6 inhibits oxidative stress-induced activation of the MAPK signaling cascade, including the phosphorylation of ERK1/2, p38 and JNK. MAPK-IN-6 eliminates intracellular reactive oxygen species (ROS) accumulation, stabilizes mitochondrial membrane potential and inhibits cell apoptosis. MAPK-IN-6 can be used for the research of ischemic stroke .
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1 Cited Publications
Cat. No.: HY-N4126
CAS No.: 6601-66-7
6-Demethoxytangeretin is a flavonoid compound that can be isolated from Citrus reticulata. 6-Demethoxytangeretin has anti-inflammatory and anti-allergic activities and can inhibit the production of IL-6 and the expression of related genes in human mast cells through the ALK and MAPK pathways. 6-Demethoxytangeretin can promote CRE-mediated transcription in hippocampal neurons .
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Cat. No.: HY-169685
CAS No.: 421578-44-1
Target:  

p38 MAPK

Research Areas:  

Inflammation/Immunology

p38 MAPK-IN-6 (compound c47) is a p38 MAPK inhibitor. p38 MAPK-IN-6 shows 14% inhibition at 10 μM .
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Cat. No.: HY-161293
CAS No.: 29368-40-9
Target:  

p38 MAPK

Research Areas:  

Cancer

p38-α MAPK-IN-6 (compound 3a) is a p38α mitogen-activated protein kinase inhibitor .
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Cat. No.: HY-E70759
Target:  

p38 MAPK

Research Areas:  

Cancer

The mitogen-activated protein kinase kinase 6 (MKK6) is one of the upstream activators of p38 MAPK. MKK6 activates myocardial cell NF-κB and inhibits apoptosis in a p38 MAPK-dependent manner. MKK6 SDTD is a mutant of MKK6. MKK6 SDTD Recombinant Human Active Protein Kinase is a recombinant MKK6 SDTD protein that can be used to study MKK6 SDTD-related functions .
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