1 Result for "

MBX 2319

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MBX 2319" in MCE Product Catalog:

Cat. No.: HY-188076
CAS No.: 375836-83-2
Target:  

Bacterial

Research Areas:  

Infection

MBX2319 is an AcrB inhibitor and antibiotic efficacy restorer that potently inhibits RND-type efflux pumps of Enterobacteriaceae species. MBX2319 increases antibacterial activity of fluoroquinolone and β-lactam antibiotics against Escherichia coli, restores antibiotic efficacy, and reduces antibiotic MIC against Gram-negative bacteria. MBX2319 has no inherent antibacterial activity against Escherichia coli and does not alter bacterial outer membrane permeability. MBX2319 can be used for the research of gram-negative bacterial infections and multidrug-resistant gram-negative bacterial infections .
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