1 Result for "

MI-2-2 (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MI-2-2 (Standard)" in MCE Product Catalog:

Cat. No.: HY-108350R
CAS No.: 1454920-20-7
Research Areas:  

Cancer

MI-2-2 (Standard) is the analytical standard of MI-2-2 (HY-108350). This product is intended for research and analytical applications. MI-2-2 is a potent menin-MLL inhibitor. MI-2-2 binds to menin with low nanomolar affinity (Kd=22nM) and very effectively disrupts the bivalent protein-protein interaction between menin and MLL. MI-2-2 has specific and very pronounced activity in MLL leukemia cells, including inhibition of cell proliferation, down-regulation of Hoxa9 expression, and differentiation .
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