MI-2-2 (Standard)

MI-2-2 (Standard) is the analytical standard of MI-2-2 (HY-108350). This product is intended for research and analytical applications. MI-2-2 is a potent menin-MLL inhibitor. MI-2-2 binds to menin with low nanomolar affinity (Kd=22nM) and very effectively disrupts the bivalent protein-protein interaction between menin and MLL. MI-2-2 has specific and very pronounced activity in MLL leukemia cells, including inhibition of cell proliferation, down-regulation of Hoxa9 expression, and differentiation.

For research use only. We do not sell to patients.

  • CAS No.: 1454920-20-7
  • Formula: C17H20F3N5S2
  • Molecular Weight:415.50
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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