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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
494 Results for "
Maleimide
" in MedChemExpress (MCE) Product Catalog:
Products (494)
494 Results for "Maleimide" in MCE Product Catalog:
Cat. No.: HY-W007324
CAS No.: 541-59-3
Category:
Alkaloids Microorganisms Pyrrole Alkaloids Other Alkaloids Endogenous metabolite Disease Research Fields Cancer
Target:
32
32 Publications Verification
Synonyms: MC-GGFG-DXD
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Research Areas:
Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813) .
18
18 Cited Publications
Synonyms: Tetraphenylethene Maleimide
6
9-ING-41 (Elraglusib) is a maleimide-based ATP-competitive and selective glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 of 0.71 μM. 9-ING-41 significantly leads to cell cycle arrest, autophagy and apoptosis in cancer cells. 9-ING-41 has anticancer activity and has the potential for enhancing the antitumor effects of chemotherapeutic agents .
5
5
5 Cited Publications
Cat. No.: HY-D0975
CAS No.: 92921-24-9
4
4 Cited Publications
Synonyms: DSPE-PEG2000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[Maleimide(polyethylene glycol)-2000] ammonium
4
2
2 Cited Publications
Synonyms: Maleimido-mono-amide-DOTA
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Research Areas:
Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
2
2 Cited Publications
Cat. No.: HY-166648
2
2 Cited Publications
Cat. No.: HY-166648A
DSPE-PEG-Maleimide ammonium (MW 2000) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG-Maleimide ammonium (MW 2000) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG (2000)-RGD. DSPE-PEG-Maleimide ammonium (MW 2000) is applicable to research on drug delivery .
2
MIRA-1 is a maleimide analogue. MIRA-1 can induce apoptosis in mutant p53 cells via restoration of p53-dependent transcriptional transactivation. MIRA-1 has anticancer activity .
1
1 Cited Publications
Synonyms: Cyanine5 Maleimide
1
1 Cited Publications
Cat. No.: HY-W808757
CAS No.: 116919-18-7
1
1 Cited Publications
Cat. No.: HY-D1744
CAS No.: 2143933-81-5
1
1 Cited Publications
Cat. No.: HY-D1565
CAS No.: 2270866-73-2
1
1 Cited Publications
Cat. No.: HY-W1048553B
1
1 Cited Publications
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Research Areas:
AMAS is a nonclaevable heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules.
1
1 Cited Publications
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Research Areas:
Mal-PEG3-NHS ester is a noncleavable ADC linker containing a Maleimide group. Mal-PEG3-NHS ester is used for making antibody-drug conjugate .
1
1 Cited Publications
Cat. No.: HY-42360
CAS No.: 64987-85-5
Target:
Research Areas:
SMCC is a protein crosslinker. SMCC contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
