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2 Results for "
Metformin hydrochloride (Standard)
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "Metformin hydrochloride (Standard)" in MCE Product Catalog:
Cat. No.: HY-17471AR
CAS No.: 1115-70-4
Synonyms: 1,1-Dimethylbiguanide hydrochloride (Standard)
Research Areas:
Metformin hydrochloride (Standard) is the analytical standard of Metformin hydrochloride (HY-17471A). This product is intended for research and analytical applications. Metformin (1,1-Dimethylbiguanide) hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to AMPK activation and enhancing insulin sensitivity, and can be used in the study of type 2 diabetes. Metformin hydrochloride exerts central glucose-lowering effects by inhibiting Ras-related protein 1 (Rap1) in SF1 hypothalamic neurons. Metformin hydrochloride also inhibits liver oxidative stress, nitrosative stress, inflammation, and apoptosis caused by liver ischemia/reperfusion injury. In addition, Metformin hydrochloride regulates the expression of autophagy-related proteins by activating AMPK and inhibiting the mTOR signaling pathway, thereby inducing tumor cell autophagy and inhibiting the growth of renal cell carcinoma in vitro and in vivo .
Target:
Research Areas:
Metformin impurity 1 (Standard) is the analytical standard of Metformin impurity 1 (HY-23875). This product is intended for research and analytical applications.
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