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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Microsomal Epoxide Hydrolase
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Microsomal Epoxide Hydrolase" in MCE Product Catalog:
Cat. No.: HY-W013053
CAS No.: 53-70-3
Synonyms: DBA; 1,2,5,6-Dibenzanthracene; Benzo[k]tetraphene
Research Areas:
Dibenz[a,h]anthracene (DBA) is an orally active polycyclic aromatic hydrocarbon, a by-product of incomplete combustion of organic matter, a potent carcinogen, and an agonist of AhR. Dibenz[a,h]anthracene induces dose-dependent increases in DNA adduct formation and lacZ mutation frequency. Dibenz[a,h]anthracene upregulates St3gal5. Dibenz[a,h]anthracene can be used in cancer-related research .
Target:
Research Areas:
mEH-IN-1 (Compound 62) is a potent microsomal epoxide hydrolase (mEH) inhibitor with the IC50 of 2.2 nM. The mEH is a mammalian α/β-fold hydrolase enzyme, expressed in almost all tissues, hydrolyzes a wide range of epoxide containing molecules. The mEH is mainly localized in the endoplasmic reticulum (ER) of eukaryotic cells. mEH-IN-1 can be used for the research of preeclampsia, hypercholanemia and cancer .
Cat. No.: HY-W101419
CAS No.: 59512-17-3
Target:
Research Areas:
Ibuprofenamide (Compound 136) is a potent microsomal epoxide hydrolase (mEH) inhibitor with an IC50 value of 96 μM. Ibuprofenamide is promising for research of preeclampsia, hypercholanemia and cancer .
Cat. No.: HY-P72184
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EPHX1; EPOX; Prev. EPHX; Epoxide Hydrolase 1 Microsomal Isoform 2; Epoxide Hydratase; Epoxide Hydrolase 1 Microsomal; Epoxide Hydrolase 1, Microsomal (Xenobiotic); Epoxide Hydrolase; Microsomal Epoxide Hydrolase; HYL1; Epoxide Hydrolase 1; MEH
Species:
Human
Source:
E. coli
Cat. No.: HY-169858
CAS No.: 3054217-03-4
Target:
Research Areas:
Prostaglandin E2 Inhibitor 3 (Compound 3) is a selectivity microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor (IC50 = 0.2 µM). Prostaglandin E2 Inhibitor 3 has higher selectivity for mPGES-1 than cyclooxygenases (COX)-1/2, 5-lipoxygenase (5-LO), and soluble epoxide hydrolase (sEH). Prostaglandin E2 Inhibitor 3 has anti-inflammatory activity and can attenuate zymosan-induced peritoneal leukocyte migration in mice .
Cat. No.: HY-P810467
Synonyms: EPHX1, Epoxide Hydrolase 1, EPHX, Epoxide Hydrolase 1, Microsomal (Xenobiotic), Epoxide Hydratase, EPOX, MEH, Epoxide Hydrolase 1 Microsomal, Microsomal Epoxide Hydrolase, EC 3.3.2.9, HYL1
Target:
Research Areas:
sEH-IN-26 is a urea structure-based soluble epoxide hydrolase (sEH) inhibitor with selectivity for mammalian cytosolic and peroxisomal sEH. sEH-IN-26 can be used for the research of inflammation and epoxide hydrolase-related diseases .
Cat. No.: HY-184799
CAS No.: 1141896-04-9
Target:
Research Areas:
sEH-IN-25 is an orally active soluble epoxide hydrolase (epoxide hydrolase) inhibitor, with an IC50 of 0.5 nM against human sEH and an IC50 of 2 nM against rat sEH. sEH-IN-25 can be used in the research of cardiovascular diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
