Prostaglandin E2 Inhibitor 3

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Prostaglandin E2 Inhibitor 3 (Compound 3) is a selectivity microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor (IC50 = 0.2 µM). Prostaglandin E2 Inhibitor 3 has higher selectivity for mPGES-1 than cyclooxygenases (COX)-1/2, 5-lipoxygenase (5-LO), and soluble epoxide hydrolase (sEH). Prostaglandin E2 Inhibitor 3 has anti-inflammatory activity and can attenuate zymosan-induced peritoneal leukocyte migration in mice.

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  • CAS No.: 3054217-03-4
  • 화학식: C21H14BrN3O2S
  • 분자량:452.32
  • 보관:
    Powder   -20°C, 3 years ; In solvent   -80°C, 6 months , -20°C, 1 month
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100 mg

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