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N-Methylmesoporphyrin IX (solution)

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N-Methylmesoporphyrin IX (solution)
N-Methylmesoporphyrin IX (solution)
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Cat. No.: HY-DY1075
CAS No.: 142234-85-3
N-Methylmesoporphyrin IX (NMM) (solution) , a widely used G-quadruplex DNA specific fluorescent binder, is an efficient probe for monitoring Aβ fibrillation. N-Methylmesoporphyrin IX is an in situ inhibitor and an ex situ monitor for Aβ amyloidogenesis both in vitro and in cells. N-Methylmesoporphyrin IX is sensitive to G-quadruplexes DNA but has no response to duplexes, triplexes and single-stranded forms DNA. N-Methylmesoporphyrin IX is nonfluorescent alone or in monomeric Aβ environments, but emits strong fluorescence through stacking with the Aβ assemblies .
Solvent and concentration: DMSO: 2 mM
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