Search Result
Results for "
NHS ester
" in MedChemExpress (MCE) Product Catalog:
242
Biochemical Assay Reagents
4
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-D1730
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Fluorescent Dye
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Others
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AF488 NHS ester is an amine specific fluorescence probe (Em=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization .
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- HY-W441011
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Liposome
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Neurological Disease
Inflammation/Immunology
Cancer
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DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .
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- HY-W441014
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Liposome
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Others
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DSPE-PEG2000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG2000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG2000-NHS can be used in the study of drug delivery .
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- HY-150241
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- HY-129526
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ADC Linkers
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Cancer
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Mal-PEG3-NHS ester is a noncleavable ADC linker containing a Maleimide group. Mal-PEG3-NHS ester is used for making antibody-drug conjugate .
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- HY-130085
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ADC Linkers
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Cancer
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Mal-PEG6-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 6-unit PEG and a NHS ester.
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- HY-126504
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ADC Linkers
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Cancer
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Mal-PEG2-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 2-unit PEG and an NHS ester.
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- HY-D1567
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Fluorescent Dye
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Others
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Cy7.5 NHS ester is a fluorescent dye. Cy7.5 NHS ester can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester can be used for fluorescent imaging study (Ex/Em = 780/820 nm) .
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- HY-136304
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- HY-D2801A
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Fluorescent Dye
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Others
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FITC-PEG1000-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG1000-NHS can be used for fluorescent labeling and imaging .
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- HY-135413A
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- HY-126502
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ADC Linkers
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Others
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Mal-C2-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-D1568
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Fluorescent Dye
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Others
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Sulfo-Cy7.5 NHS ester is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester can be used for the research of NIR imaging applications .
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- HY-D1800
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VF 680 SE
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Fluorescent Dye
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Others
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Vari Fluor 680 SE (VF 680 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=680 nm/700 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
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- HY-D1801
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VF 488 SE
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Fluorescent Dye
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Others
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Vari Fluor 488 SE (VF 488 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=488 nm/513 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
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- HY-156991
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NODA-GA-NHS ester
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EGFR
Radionuclide-Drug Conjugates (RDCs)
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Cancer
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NODAGA-NHS (NODA-GA-NHS ester) is the activated ester form of the NODAGA chelator. NODAGA-NHS conjugates with Trastuzumab (HY-P9907) to form NODAGA-Trastuzumab, a conjugate that can chelate 64Cu for the preparation of radiotracers. NODAGA-NHS covalently binds to the amino group of lactosamine derivatives to form radiotracer precursors. [ 64Cu]NODAGA-trastuzumab enables PET imaging of tumors expressing HER2. NODAGA-NHS is used in studies of HER2-positive breast cancer and ovarian adenocarcinoma .
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- HY-150014
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Others
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Others
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AMT-NHS is an RNA-protein crosslinker. AMT-NHS is composed of a psoralen derivative and an N-hydroxysuccinimide ester group which react with RNA bases and primary amines of protein, respectively. AMT-NHS can penetrate into living yeast cells and crosslink Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different crosslinking patterns and targets both single- and double-stranded regions of RNA. AMT-NHS can be used for capturing diverse RNA-protein interactions in cells .
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- HY-W441013
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Liposome
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Others
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DSPE-PEG1000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG1000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG1000-NHS can be used in the study of drug delivery .
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- HY-174893
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Biochemical Assay Reagents
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Others
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Azido-PEG20-NHS ester is a PEG derivative that can be used for drug delivery and other research. Azido-PEG20-NHS ester is a click chemistry reagent. Azido-PEG20-NHS contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group. Azido-PEG20-NHS can also undergo ring strain driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
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- HY-170528
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PROTAC Linkers
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Others
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DBCO-PEG3-NHS is a biochemical assay reagent, that can be used to chemically modify proteins and antibodies with an alkynyl (DBCO) or N-hydroxysuccinimide (NHS) ester group. DBCO-PEG3-NHS can be used as a linker in PROTAC synthesis or for drug delivery and the development of biosensors and diagnostic reagents .
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- HY-156383
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PROTAC Linkers
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Cancer
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SCO-PEG3-NHS is a PEG linker with a terminal imine(NH) group. SCO-PEG3-NHS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-136133
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ADC Linkers
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Cancer
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NHS-PEG2-SS-PEG2-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-W190908A
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Biochemical Assay Reagents
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Others
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Desthiobiotin-PEG4-NHS ester is a PEG derivative composed of desthiobiotin, 4 PEG units, and NHS ester. NHS ester can be conjugated to amino acids or other molecules containing amino groups.
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- HY-D2178
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Fluorescent Dye
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Others
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AF 568 NHS ester is a derivative of the orange fluorescent dye AF 568. AF 568 NHS ester is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling. AF 568 exhibits maximum absorption wavelength of 579 nm and the maximum emission wavelength of 603 nm .
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- HY-D1802
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VF 425 SE
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Fluorescent Dye
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Others
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Vari Fluor 425 SE (VF 425 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=430 nm/475 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
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- HY-D1790
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VF 640 SE
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Fluorescent Dye
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Others
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Vari Fluor 640 SE (VF 640 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=648 nm/664 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
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- HY-140341A
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PROTAC Linkers
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Others
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Sulfo-NHS-Acetate sodium is an alkyl chain-based PROTAC linker. Sulfo-NHS-Acetate sodium can be used in the synthesis of PROTACs .
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- HY-W441016
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Liposome
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Others
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DSPE-PEG5000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG5000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG5000-NHS can be used in the study of drug delivery .
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- HY-135413B
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Sulfo-Cyanine5 NHS ester triethylamine
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DNA Stain
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Others
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MeCY5-NHS ester (potassium) is a reactive dye and can be used for labeling protein nucleic acid .
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- HY-D1791
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VF 750 SE
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Fluorescent Dye
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Others
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Vari Fluor 750 SE (VF 750 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=747 nm/770 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
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- HY-D2801B
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Fluorescent Dye
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Others
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FITC-PEG3400-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG3400-NHS can be used for fluorescent labeling and imaging .
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- HY-W190908C
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Biochemical Assay Reagents
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Others
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Desthiobiotin-PEG12-NHS ester is a PEG derivative composed of desthiobiotin, 12 PEG units, and NHS ester. NHS ester can be conjugated to amino acids or other molecules containing amino groups.
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- HY-W190908B
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Biochemical Assay Reagents
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Others
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Desthiobiotin-PEG6-NHS ester is a PEG derivative composed of desthiobiotin, 6 PEG units, and NHS ester. NHS ester can be conjugated to amino acids or other molecules containing amino groups.
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- HY-D2956
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CLIP-GLA-NHS
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Biochemical Assay Reagents
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Others
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BC-GLA-NHS (CLIP-GLA-NHS) is a NHS-labeled CLIP tag, which is an amine-reactive crosslinker and can achieve site-specific protein labeling. The NHS ester of BC-GLA-NHS reacts with the primary amine of the target molecule (such as antibodies, quantum dots) in a pH 7.5-8.5 buffer solution to form a stable amide bond. After coupling, the BC molecule undergoes a nucleophilic substitution reaction with the active site (Cys) of the CLIP-tagged fusion protein, releasing benzylcytosine and forming an irreversible thioether bond, achieving covalent labeling. BC-GLA-NHS can be used for click chemistry labeling .
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- HY-W190842
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Biochemical Assay Reagents
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Others
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m-PEG2-NHS ester is a PEG linker containing an NHS ester. The NHS ester of m-PEG2-NHS ester is used to label primary amines (-NH2) of proteins, amine-modified oligonucleotides and other amine-containing molecules. The hydrophilic PEG spacer effectively improves solubility in aqueous media. m-PEG2-NHS ester can be used in studies related to bioconjugation with ADC, proteins, peptides and other molecules .
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- HY-W441012
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Liposome
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Others
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DSPE-PEG600-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG600-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG600-NHS can be used in the study of drug delivery .
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- HY-174888
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Biochemical Assay Reagents
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Others
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DBCO-PEG16-NHS ester is a PEG derivative consisting of DBCO, PEG units, and NHS ester. NHS ester can bind to amino acids or other molecules containing amino groups. DBCO-PEG16-NHS ester contains a DBCO group and can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
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- HY-D2890
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Fluorescent Dye
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Others
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5-TAMRA-NHS is a fluorescent dye that combines 5-TAMRA (HY-15942) with a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. 5-TAMRA-NHS can be used for fluorescent labeling and imaging (Ex/Em = 541/567 nm) .
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- HY-D2291
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Fluorescent Dye
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Others
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BODIPY TMR NHS ester is bright, orange fluorescent dye with Ex/Em of 544/570 nm. The NHS ester (or succinimidyl ester) of BODIPY TMR NHS ester is a popular tool for conjugating the dye to a protein or antibody. NHS esters can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
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- HY-151686
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Biochemical Assay Reagents
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Others
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Bz-(Me)Tz-NHS is a methyltetrazine carboxylic acid NHS ester that enables conjugation of the tetrazine moiety to the 5' end of oligonucleotides via amide coupling reaction, and it is used in oligonucleotide template-mediated fluorescent bioorthogonal cycloaddition reactions. Bz-(Me) Tz-NHS is applicable to click chemistry-related studies .
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- HY-D1798
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VF 350 SE
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Fluorescent Dye
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Others
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Vari Fluor 350 SE (VF 350 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=350 nm/448 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
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- HY-D1796
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VF 594 SE
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Fluorescent Dye
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Others
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Vari Fluor 594 SE (VF 594 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=585 nm/609 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
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- HY-D2801
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Fluorescent Dye
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Others
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FITC-PEG400-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG400-NHS can be used for fluorescent labeling and imaging .
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- HY-118431
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Biochemical Assay Reagents
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Others
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DMABA NHS ester can chemically react with the primary amine groups of the major phospholipid component of the cell membrane, Phosphatidylethanolamine (PE). Through precursor ion scanning, all PE subclasses labeled with DMABA can be detected. DMABA NHS ester can be used in combination with isotope-labeled compounds such as DMABA-d6 NHS ester, DMABA-d10 NHS ester, and DMABA-d4 NHS ester to observe changes in the distribution of PE lipids and the formation of novel PE lipid products .
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- HY-141166A
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Biochemical Assay Reagents
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Cancer
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(S,E)-TCO2-PEG3-NHS ester is NH2 reactive, and can be used in chemical synthesis. (S,E)-TCO2-PEG3-NHS ester contains TCO groups, which can undergo specific "click" reactions with tetrazine groups .
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- HY-D2290
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Fluorescent Dye
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Others
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Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .
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- HY-135413
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- HY-D1799
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VF 568 SE
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Fluorescent Dye
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Others
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Vari Fluor 568 SE (VF 568 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=573 nm/595 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
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- HY-D1794
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VF 405 SE
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Fluorescent Dye
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Others
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Vari Fluor 405 SE (VF 405 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=399 nm/421 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
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- HY-D1797
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VF 660 SE
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Fluorescent Dye
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Others
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Vari Fluor 660 SE (VF 660 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=660 nm/679 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
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- HY-D1792
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VF 555 SE
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Fluorescent Dye
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Others
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Vari Fluor 555 SE (VF 555 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=550 nm/561 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
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- HY-D1795
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VF 532 SE
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Fluorescent Dye
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Others
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Vari Fluor 532 SE (VF 532 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=532 nm/545 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
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- HY-D1803
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VF 565 SE
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Fluorescent Dye
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Others
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Vari Fluor 565 SE (VF 565 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=563 nm/594 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
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- HY-D2801C
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Fluorescent Dye
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Others
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FITC-PEG5000-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG5000-NHS can be used for fluorescent labeling and imaging .
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- HY-D2105
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Fluorescent Dye
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Others
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TAMRA-PEG3-NHS is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NHS contains NHS groups that react with ammonia to form ester bonds.
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- HY-D2106
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Fluorescent Dye
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Others
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TAMRA-PEG4-NHS is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-NHS contains NHS groups that react with ammonia to form ester bonds.
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- HY-D2107
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Fluorescent Dye
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Others
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TAMRA-PEG8-NHS is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-NHS contains NHS groups that react with ammonia to form ester bonds.
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- HY-174948
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NHS-PEG1000-Aldehyde
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Biochemical Assay Reagents
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Others
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NHS-PEG1000-CHO (NHS-PEG1000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
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- HY-174948C
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NHS-PEG5000-Aldehyde
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Biochemical Assay Reagents
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Others
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NHS-PEG5000-CHO (NHS-PEG5000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
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- HY-151758
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ADC Linkers
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Others
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Methyltetrazine-PEG12-NHS ester is a click chemistry reagent containing an azide group. Methyltetrazine-PEG12-NHS ester reacts with compounds containing TCO to form stable covalent bonds .
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- HY-156385
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PROTAC Linkers
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Cancer
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SCO-PEG8-NHS SCO is a PROTAC linker and belongs to the PEG class. SCO-PEG8-NHS SCO contains SCO and NHS esters that can be covalently bound to amino groups, respectively. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
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- HY-D2477
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Fluorescent Dye
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Others
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Sulfo-QSY21-NHS is a fluorescent dye, which contains a NHS group that can react with amine groups (-NH2) in proteins or other molecules to form stable amide bonds. Sulfo-QSY21-NHS can be used in the synthesis of activity-based probes (ABPs) .
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- HY-138509
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PROTAC Linkers
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Cancer
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NHS ester-PEG13-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-138511
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PROTAC Linkers
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Cancer
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NHS ester-PEG7-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-132103
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PROTAC Linkers
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Cancer
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NHS ester-PEG3-S-methyl ethanethioate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W451415
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Biochemical Assay Reagents
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Others
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NHS-PEG-NHS is a derivative of activated polyethylene glycol (PEG) that can modify functional groups on protein surfaces via covalent binding. NHS-PEG-NHS serves as a bioconjugation modification reagent for modifying proteins, enzymes, peptides and antibodies .
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- HY-D2884D
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Rhodamine B-PEG3400-NHS
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Fluorescent Dye
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Others
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RB-PEG3400-NHS (Rhodamine B-PEG3400-NHS) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. RB-PEG3400-NHS can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
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- HY-D2884E
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Rhodamine B-PEG5000-NHS
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Fluorescent Dye
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Others
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RB-PEG5000-NHS (Rhodamine B-PEG5000-NHS) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. RB-PEG5000-NHS can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
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- HY-D2884H
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Rhodamine B-PEG10000-NHS
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Fluorescent Dye
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Others
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RB-PEG10000-NHS (Rhodamine B-PEG10000-NHS) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. RB-PEG10000-NHS can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
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- HY-D2884A
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Rhodamine B-PEG600-NHS
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Fluorescent Dye
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Others
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RB-PEG600-NHS (Rhodamine B-PEG600-NHS) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. RB-PEG600-NHS can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
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- HY-D2884B
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Rhodamine B-PEG1000-NHS
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Fluorescent Dye
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Others
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RB-PEG1000-NHS (Rhodamine B-PEG1000-NHS) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. RB-PEG1000-NHS can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
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- HY-D2884C
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Rhodamine B-PEG2000-NHS
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Fluorescent Dye
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Others
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RB-PEG2000-NHS (Rhodamine B-PEG2000-NHS) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. RB-PEG2000-NHS can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
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- HY-D2884
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Rhodamine B-PEG400-NHS
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Fluorescent Dye
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Others
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RB-PEG400-NHS (Rhodamine B-PEG400-NHS) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. RB-PEG400-NHS can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
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- HY-W615173
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Biochemical Assay Reagents
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Others
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NHS ester-C2-NHCO-C2-NHS is a heterobifunctional PEG linker, featuring a terminal NHS ester that can be used to label amine compounds and maleimide group for reactions with thiol groups.
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- HY-W190745
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Biochemical Assay Reagents
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Others
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DNP-PEG8-NHS ester is a PEG derivative that contains DNP (2,4-dinitroaniline), eight PEG units, and NHS ester. NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). DNP-PEG8-NHS ester can be used for drug delivery.
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- HY-W190745A
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Biochemical Assay Reagents
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Others
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DNP-PEG2-NHS ester is a PEG derivative that contains DNP (2,4-dinitroaniline), two PEG units, and NHS ester. NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). DNP-PEG2-NHS ester can be used for drug delivery.
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-
- HY-W190745B
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Biochemical Assay Reagents
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Others
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DNP-PEG3-NHS ester is a PEG derivative that contains DNP (2,4-dinitroaniline), three PEG units, and NHS ester. NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). DNP-PEG3-NHS ester can be used for drug delivery.
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-
- HY-174948B
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NHS-PEG3400-Aldehyde
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Biochemical Assay Reagents
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Others
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NHS-PEG3400-CHO (NHS-PEG3400-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
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- HY-174948A
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NHS-PEG2000-Aldehyde
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Biochemical Assay Reagents
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Others
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NHS-PEG2000-CHO (NHS-PEG2000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
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- HY-W1120833
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- HY-174891
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Biochemical Assay Reagents
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Others
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Betiatide-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
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- HY-141121
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Drug Intermediate
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Others
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T-Butoxycarbonyl-PEG1-NHS ester contains a t-boc protecting group and an NHS ester moiety. T-Butoxycarbonyl-PEG1-NHS ester can be used for the modification and labeling of biomolecules.
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- HY-182833A
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Biochemical Assay Reagents
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Others
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DPPE-PEG2000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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-
- HY-182833D
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Biochemical Assay Reagents
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Others
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DPPE-PEG10000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG10000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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-
- HY-182833B
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Biochemical Assay Reagents
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Others
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DPPE-PEG3400-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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-
- HY-183104D
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Biochemical Assay Reagents
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Others
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DSG-PEG10000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG10000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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-
- HY-183104
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Biochemical Assay Reagents
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Others
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|
DSG-PEG1000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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-
- HY-183016
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Biochemical Assay Reagents
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Others
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DMPE-PEG1000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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-
- HY-183104B
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Biochemical Assay Reagents
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Others
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|
DSG-PEG3400-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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-
- HY-183104A
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Biochemical Assay Reagents
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Others
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DSG-PEG2000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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-
- HY-183016C
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Biochemical Assay Reagents
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Others
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DMPE-PEG5000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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-
- HY-183016B
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Biochemical Assay Reagents
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Others
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|
DMPE-PEG3400-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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-
- HY-182833
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Biochemical Assay Reagents
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Others
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DPPE-PEG1000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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-
- HY-183104C
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Biochemical Assay Reagents
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Others
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DSG-PEG5000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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-
- HY-182833C
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Biochemical Assay Reagents
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Others
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DPPE-PEG5000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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-
- HY-183016A
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Biochemical Assay Reagents
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Others
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DMPE-PEG2000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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-
- HY-183016D
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Biochemical Assay Reagents
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Others
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DMPE-PEG10000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG10000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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-
- HY-183162A
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Biochemical Assay Reagents
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Others
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Glucose-PEG2000-NHS is a conjugate composed of glucose, PEG chains, and an active ester (NHS). Glucose-PEG2000-NHS combines the targeted recognition capabilities of glucose with the ability to rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and amino-modified small molecules) to form stable amide bonds in an NHS ester. This allows for applications such as constructing targeted drug delivery systems and modifying nanoparticles.
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-
- HY-183162D
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Biochemical Assay Reagents
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Others
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Glucose-PEG10000-NHS is a conjugate composed of glucose, PEG chains, and an active ester (NHS). Glucose-PEG10000-NHS combines the targeted recognition capabilities of glucose with the ability to rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and amino-modified small molecules) to form stable amide bonds in an NHS ester. This allows for applications such as constructing targeted drug delivery systems and modifying nanoparticles.
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-
- HY-185776
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- HY-183162C
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Biochemical Assay Reagents
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Others
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Glucose-PEG5000-NHS is a conjugate composed of glucose, PEG chains, and an active ester (NHS). Glucose-PEG5000-NHS combines the targeted recognition capabilities of glucose with the ability to rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and amino-modified small molecules) to form stable amide bonds in an NHS ester. This allows for applications such as constructing targeted drug delivery systems and modifying nanoparticles.
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-
- HY-183162B
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Biochemical Assay Reagents
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Others
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|
Glucose-PEG3400-NHS is a conjugate composed of glucose, PEG chains, and an active ester (NHS). Glucose-PEG3400-NHS combines the targeted recognition capabilities of glucose with the ability to rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and amino-modified small molecules) to form stable amide bonds in an NHS ester. This allows for applications such as constructing targeted drug delivery systems and modifying nanoparticles.
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-
- HY-183162
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Biochemical Assay Reagents
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Others
|
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Glucose-PEG1000-NHS is a conjugate composed of glucose, PEG chains, and an active ester (NHS). Glucose-PEG1000-NHS combines the targeted recognition capabilities of glucose with the ability to rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and amino-modified small molecules) to form stable amide bonds in an NHS ester. This allows for applications such as constructing targeted drug delivery systems and modifying nanoparticles.
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-
- HY-141170
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ADC Linkers
PROTAC Linkers
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Cancer
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TCO-PEG12-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG12-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-126886
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ADC Linkers
PROTAC Linkers
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Cancer
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|
Mal-PEG1-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG1-NHS ester is PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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-
- HY-130410
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ADC Linkers
PROTAC Linkers
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Cancer
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|
Bis-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-203300D
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Biochemical Assay Reagents
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Others
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DOPE-PEG1000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
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-
- HY-203300C
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Biochemical Assay Reagents
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Others
|
|
DOPE-PEG5000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
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-
- HY-203300B
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Biochemical Assay Reagents
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Others
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|
DOPE-PEG3400-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
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-
- HY-203300A
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Biochemical Assay Reagents
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Others
|
|
DOPE-PEG1000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
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-
- HY-203300
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Biochemical Assay Reagents
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Others
|
|
DOPE-PEG2000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
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-
- HY-W588715D
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Biochemical Assay Reagents
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Others
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|
Acid-PEG6-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
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-
- HY-148142
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- HY-W588715A
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Biochemical Assay Reagents
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Others
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|
Acid-PEG2-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
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-
- HY-174895
-
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Biochemical Assay Reagents
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Others
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|
Propargyl-PEG12-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
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-
- HY-148143
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-
- HY-W588715C
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Biochemical Assay Reagents
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Others
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|
Acid-PEG1-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
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-
- HY-W588715
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Biochemical Assay Reagents
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Others
|
|
Acid-PEG8-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
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-
- HY-174889
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Biochemical Assay Reagents
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Others
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|
Acetal-PEG18-NHS is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
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-
- HY-W588715B
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Biochemical Assay Reagents
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Others
|
|
Acid-PEG12-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
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-
- HY-W879004
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Biochemical Assay Reagents
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Others
|
|
m-PEG16-NHS ester is a PEG derivative composed of an NHS ester that can be conjugated to amino acids or other molecules containing amino groups .
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-
- HY-160541
-
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|
ADC Linkers
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Inflammation/Immunology
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|
Mal-PEG2000-NHS ester is a PEG linker, can be used to link lipoteichoic acid (LTA) and CpG DNA fragments to synthesis CpG-TA Heterodiners. Mal-PEG2000-NHS ester can be used for immune stimulation research .
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-
- HY-117009
-
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|
ADC Linkers
PROTAC Linkers
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Cancer
|
|
Bis-PEG9-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG9-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-126889
-
|
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
|
Bis-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-130825
-
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|
PROTAC Linkers
ADC Linkers
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Cancer
|
|
Bis-PEG13-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG13-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-130827
-
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|
PROTAC Linkers
ADC Linkers
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Cancer
|
|
Bis-PEG21-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG21-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-130826
-
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|
ADC Linkers
PROTAC Linkers
|
Cancer
|
|
Bis-PEG17-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG17-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-130828
-
|
|
PROTAC Linkers
ADC Linkers
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Cancer
|
|
Bis-PEG25-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG25-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-126890
-
|
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
|
Bis-PEG7-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-130824
-
|
|
PROTAC Linkers
ADC Linkers
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Cancer
|
|
Bis-PEG10-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG10-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-W800684
-
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Biochemical Assay Reagents
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Others
|
|
Benzyloxy carbonyl-PEG4-NHS ester is a reagent with a benzyl protecting group and an NHS ester. The NHS ester reacts with primary amines (-NH2). The benzyl protecting group can be removed by hydrogenolysis.
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-
- HY-126974
-
|
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG3-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG3-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-126885
-
|
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-130388
-
|
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG5-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130381
-
|
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG7-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG7-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130385
-
|
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG6-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130376
-
|
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG8-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG8-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-174892B
-
|
|
Biochemical Assay Reagents
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Others
|
|
Biotin-PEG20-NHS ester is a PEG derivative composed of Biotin, 20 PEG units, and NHS ester. Biotin can form a stable non-covalent bond with streptavidin. NHS ester can bind to amino acids or other molecules containing amino groups .
|
-
- HY-W440697
-
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|
Biochemical Assay Reagents
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Others
|
|
Cholesterol-PEG1000-NHS is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG1000-NHS can be used in drug delivery research .
|
-
- HY-W440702
-
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|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG2000-NHS is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG2000-NHS can be used in drug delivery research .
|
-
- HY-W440704
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG5000-NHS is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG5000-NHS can be used in drug delivery research .
|
-
- HY-174892A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG32-NHS ester is a PEG derivative composed of Biotin, 32 PEG units, and NHS ester. Biotin can form a stable non-covalent bond with streptavidin. NHS ester can bind to amino acids or other molecules containing amino groups .
|
-
- HY-W440703
-
|
|
Biochemical Assay Reagents
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Others
|
|
Cholesterol-PEG3400-NHS is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG3400-NHS can be used in drug delivery research .
|
-
- HY-W800686
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Acid-PEG4-NHS ester is a PEG linker with a carboxylic acid and an NHS ester. Both functional group can react with primary amine, but the carboxylic acid will need activators such as EDC or HATU.
|
-
- HY-118431S3
-
-
- HY-118431S2
-
-
- HY-118431S
-
-
- HY-158072
-
|
|
Biochemical Assay Reagents
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
DOTAM-NHS-ester is a bifunctional chelator and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTAM-NHS-ester combines the efficient metal chelating ability of DOTAM macrocyclic ligands with the bioconjugation function of NHS ester active groups, and can be widely used in the biomedical field for metal labeling, molecular imaging and drug delivery development .
|
-
- HY-133066
-
|
|
PROTAC Linkers
ADC Linkers
|
Inflammation/Immunology
Cancer
|
|
m-PEG6-NHS ester is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-17664
-
|
2’-Sulfo-NHS-succinyl-paclitaxel
|
Drug Derivative
Microtubule/Tubulin
|
Cancer
|
|
Paclitaxel succinate sulfo-NHS ester is a derivative of Paclitaxel (HY-B0015). Paclitaxel succinate sulfo-NHS ester can be used for the research of cancer .
|
-
- HY-174935A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG2000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .
|
-
- HY-174935B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG3400-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .
|
-
- HY-174935
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG1000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .
|
-
- HY-174935C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG5000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .
|
-
- HY-174935D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG10000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .
|
-
- HY-151727
-
|
|
ADC Linkers
|
Others
|
|
Norbornene-NHS is a norbornene-functionalized antibody-drug conjugate linker (ADC Linker) bearing an NHS ester, which is applicable for highly efficient and specific antibody conjugation reactions in ADC research and development. Norbornene-NHS also acts as an azide-group-containing click chemistry reagent, serving as a dienophile for copper-free click reaction conjugation .
|
-
- HY-126511
-
|
|
ADC Linkers
|
Cancer
|
|
Propargyl-C1-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC). Propargyl-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-126512
-
|
|
ADC Linkers
|
Cancer
|
|
Propargyl-C2-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC). Propargyl-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-156384
-
-
- HY-150311
-
|
|
PROTAC Linkers
|
Others
|
|
endo-BCN-PEG24-NHS ester is composed of a benzocyclonorbornene, a twenty-tetramer of polyethylene glycol (PEG) and an N-hydroxysuccinimide ester. endo-BCN-PEG24-NHS is utilized as linker for synthesis of PROTAC molecule .
|
-
- HY-D1848
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3-NHS disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS disodium contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS disodium can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
|
-
- HY-D1848A
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3-NHS ditriethylamine is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS ditriethylamine contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS ditriethylamine can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
|
-
- HY-128890
-
|
|
ADC Linkers
|
Cancer
|
|
DOTA-NHS-ester is a linker for affibody molecules and is applied in small animals PET, SPECT, and CT. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for the detection of tumors .
|
-
- HY-176879
-
|
|
Drug Derivative
Bacterial
|
Infection
|
|
NHS-PEG2000-Mannose is an NHS-PEG-Mannose containing PEG2000. NHS-PEG-Mannose is a D-mannose derivative and linker. NHS-PEG-Mannose can bind to phage coat proteins via amino-carboxyl reaction to form mannose-modified phage (Man-phage) .
|
-
- HY-W1120356B
-
-
- HY-W1120356A
-
-
- HY-W1120356C
-
-
- HY-W1120356
-
-
- HY-140272
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140273
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG8-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-138744
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG13-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133439
-
|
|
PROTAC Linkers
ADC Linkers
|
Cancer
|
|
BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140274
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG12-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140271
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG1-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-138734
-
|
|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D2767
-
|
|
Fluorescent Dye
|
Others
|
|
MB 660R NHS Ester is a fluroescent agent with a terminal NHS ester group.MB 660R NHS Ester is a far-red fluorescent dye that has a maximal absorption of 665 nm and emission at 690 nm. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-141171
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG24-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-141167A
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-126513
-
|
|
ADC Linkers
|
Cancer
|
|
Propargyl-PEG1-NHS ester is a nonclaevable 1-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-PEG1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-126516
-
|
|
ADC Linkers
|
Cancer
|
|
Propargyl-PEG4-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W437745
-
|
|
Fluorescent Dye
|
Others
|
|
Desthiobiotin-NHS ester is a biotinylated biochemical assay reagent that reacts with amine groups (such as lysine residues) of proteins or other biomolecules to form stable amide bonds. Desthiobiotin-NHS ester can be used as probes for metalloproteins .
|
-
- HY-W040289
-
|
|
ADC Linkers
|
Cancer
|
|
Mal-amido-PEG2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
-
- HY-111456
-
|
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
|
DBCO-NHCO-PEG4-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-154834
-
|
|
Fluorescent Dye
|
Others
|
|
BHQ-1 NHS is a quencher and fluorescent dye. BHQ-1 NHS enables direct labeling via fluorescently labeled nucleotides .
|
-
- HY-126908A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Tetrazine-Ph-PEG17-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
|
-
- HY-160773
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-202399
-
|
|
PROTAC Linkers
|
Others
|
|
TCO-PEG2-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG2-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups .
|
-
- HY-171559
-
|
|
PROTAC Linkers
|
Others
|
|
TCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG5-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups .
|
-
- HY-W800711
-
|
|
Biochemical Assay Reagents
|
Others
|
|
SPDP-Gly-Pro-NHS ester is a linker with SPDP and NHS ester moieties. The SPDP is an amine and thiol reactive crosslinker. It is also membrane permeable, allowing it to participate in intracellular crosslinking reactions. The NHS ester is amine reactive and forms stable amide bonds.
|
-
- HY-124323
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-D1309
-
|
|
Fluorescent Dye
|
|
|
Sulfo-cyanine3 NHS ester sodium is a water-soluble cyanine dye that contains NHS ester groups and is amino-reactive.
|
-
- HY-130291
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
|
-
- HY-174264B
-
-
- HY-174264C
-
-
- HY-133064
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-122413
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG7-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-126887
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-130446
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG9-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-174264A
-
-
- HY-133065
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG5-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-130086
-
|
|
ADC Linkers
|
Cancer
|
|
Bis-PEG4-NHS ester is a crosslinking reagent and amine-reactive modulator [2].Bis-PEG4-NHS ester reacts with primary amine groups on liposome surfaces via amide bond formation to covalently attach dibenzylcyclooctyne groups, with a hydrophilic PEG4 spacer reducing steric hindrance for subsequent click chemistry [1].Bis-PEG4-NHS ester enables site-specific antibody coupling to liposome surfaces via copper-free strain-promoted alkyne-azide cycloaddition click chemistry without disrupting liposome structure in minimal organic solvent volumes [1].Bis-PEG4-NHS ester undergoes hydrolysis during annealing to form -COOH groups that interact with PbI and FAI to enhance perovskite structural integrity, passivate defects, and modulate nucleation kinetics to regulate crystal growth [2].Bis-PEG4-NHS ester enhances device efficiency and long-term stability when used as an antisolvent additive for p-i-n perovskite solar cells .
|
-
- HY-174897
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG4-NHS ester is a lipid-containing PEG derivative that can be used to form micelles as nanoparticles for drug delivery . NHS esters can be conjugated to amino acids or other molecules containing an amino group.
|
-
- HY-W588706
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Tetrazine-PEG5-SS-NHS ester is a heterobifunctional crosslinking agent, a PEG derivative composed of NHS ester. NHS ester can bind to amino acids or other amino-containing molecules. Tetrazine-PEG5-SS-NHS ester is used in bioconjugation, bioorthogonal chemistry, and delivery.
|
-
- HY-133493
-
|
|
PROTAC Linkers
|
Cancer
|
|
Folate-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140615
-
|
|
PROTAC Linkers
|
Cancer
|
|
DNP-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130830
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140963
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141109
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG25-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141357
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141272
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141394
-
|
|
PROTAC Linkers
|
Cancer
|
|
Chloroacetamido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141271
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141106
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141269
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130672
-
|
|
PROTAC Linkers
|
Cancer
|
|
Hydroxy-PEG3-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141100
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-PEG11-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135819
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-143855
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133378
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141166
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141101
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135941
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG9-NHS Ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126717
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141096
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134683
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ms-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138721
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132018
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133389
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG36-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141083
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fluorescein-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141082
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fluorescein-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141270
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W019794
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG16-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130195
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141107
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141097
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138720
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141098
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-PEG25-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-122459
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130829
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG15-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140891
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D2329
-
|
|
Fluorescent Dye
|
Others
|
|
Fluorescein-PEG4-NHS ester is a colorimetric probe formed by the reaction of adipic dihydrazide and fluorescein isothiocyanate .
|
-
- HY-141102
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141105
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG11-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138412
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetic-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133482
-
|
|
PROTAC Linkers
|
Cancer
|
|
Iodo-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138718
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG14-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138726
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141104
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141387
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetamido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140890
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138430
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141169
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-140614
-
|
|
PROTAC Linkers
|
Cancer
|
|
DNP-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141356
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-122456
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140892
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130903
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG49-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138422
-
|
|
PROTAC Linkers
|
Cancer
|
|
Iodoacetyl-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141110
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG37-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141168
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-132017
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromo-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132016
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141085
-
|
|
PROTAC Linkers
|
Cancer
|
|
Carboxyfluorescein-PEG12-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141108
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG17-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126882
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D0802
-
|
Biotin N-hydroxysuccinimide ester; NHS-Biotin
|
Fluorescent Dye
|
Others
|
|
Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.
|
-
- HY-183134A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
C16-PEG3400-NHS is a conjugate composed of hexadecyl (C16, i.e., palmitoyl), a PEG chain, and an active ester (NHS). C16-PEG3400-NHS combines the membrane compatibility of lipids with glucose as an active site for sugar recognition or subsequent conjugation reactions, making it suitable for research in biomaterial construction and drug delivery.
|
-
- HY-183169B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
C18-PEG5000-NHS is a conjugate composed of octadecyl (C18 aliphatic chain), PEG chains, and an active ester (NHS). C18-PEG5000-NHS combines the membrane compatibility of lipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
|
-
- HY-183134B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
C16-PEG5000-NHS is a conjugate composed of hexadecyl (C16, i.e., palmitoyl), a PEG chain, and an active ester (NHS). C16-PEG5000-NHS combines the membrane compatibility of lipids with glucose as an active site for sugar recognition or subsequent conjugation reactions, making it suitable for research in biomaterial construction and drug delivery.
|
-
- HY-183169
-
|
|
Biochemical Assay Reagents
|
Others
|
|
C18-PEG2000-NHS is a conjugate composed of octadecyl (C18 aliphatic chain), PEG chains, and an active ester (NHS). C18-PEG2000-NHS combines the membrane compatibility of lipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
|
-
- HY-183169A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
C18-PEG3400-NHS is a conjugate composed of octadecyl (C18 aliphatic chain), PEG chains, and an active ester (NHS). C18-PEG3400-NHS combines the membrane compatibility of lipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
|
-
- HY-183134
-
|
|
Biochemical Assay Reagents
|
Others
|
|
C16-PEG2000-NHS is a conjugate composed of hexadecyl (C16, i.e., palmitoyl), a PEG chain, and an active ester (NHS). C16-PEG2000-NHS combines the membrane compatibility of lipids with glucose as an active site for sugar recognition or subsequent conjugation reactions, making it suitable for research in biomaterial construction and drug delivery.
|
-
- HY-145090
-
|
|
PROTAC Linkers
ADC Linkers
|
Others
|
|
DBCO-N-bis(PEG4-NHS ester) is a PEG linker which contains two PEG4-NHS ester and a DBCO group. DBCO-N-bis(PEG4-NHS ester) is useful for protein modification or labeling. DBCO-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-42984
-
|
|
Biochemical Assay Reagents
|
Others
|
|
BHQ-2 NHS is a dark quencher with no native emission due to the polyaromatic-azo backbone and a terminal NHS ester. UBHQ-2 NHS has a wide and intense quenching range from 560-670 nm, which makes it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with orange to far-red emitting dyes. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-171713
-
|
|
Drug Intermediate
|
Cancer
|
|
LBA-NHS (Figure 1, Step 2) is a derivative of lactobionic acid (LBA). LBA-NHS can be used to modify lipids and serve as a coating for biological materials, ensuring that LBA can efficiently and specifically bind to the carrier molecules .
|
-
- HY-130474
-
|
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
|
Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130184
-
|
|
ADC Linkers
PROTAC Linkers
|
Cancer
|
|
Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG8-NHS ester is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-164165
-
|
|
Microtubule/Tubulin
Drug Derivative
|
Cancer
|
|
Paclitaxel-2′-succinate NHS ester is a paclitaxel derivative with a succinic acid linker, in which the carboxyl group is activated by the NHS ester. The NHS ester group is highly reactive toward amino or hydroxyl groups and can be used to conjugate with other molecules such as peptides, proteins, antibodies, enzymes or polymers. Paclitaxel-2′-succinate NHS ester can be used in the development of nanomedicines and in the study of cancer therapy .
|
-
- HY-W190907
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Trifluoroacetamidoethyl-SS-propionic NHS ester is a cleavable linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The disulfide bond can be cleaved under reduction conditions.
|
-
- HY-130089
-
|
|
ADC Linkers
|
Cancer
|
|
Bis-PEG1-NHS ester is a nonclaevable 1-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
- HY-124377
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-C6-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135915
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-C5-NHS Ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135920
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-C10-NHS Ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130088
-
|
|
ADC Linkers
|
Cancer
|
|
Bis-PEG2-NHS ester is a nonclaevable 2-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
- HY-114512
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG1-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-140342
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-C16-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W009037
-
|
|
PROTAC Linkers
|
Cancer
|
|
Maleimide-C10-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126888
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-PEG5-NHS ester is an Alkyl/ether and PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-130087
-
|
|
ADC Linkers
|
Cancer
|
|
Bis-PEG3-NHS ester is a nonclaevable 3-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
- HY-141167B
-
|
|
ADC Linkers
|
Cancer
|
|
(S)-TCO-PEG4-NHS ester is an ADC linker containing 4 PEG units. (S)-TCO-PEG4-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-174289
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TMTHSI succinimide NHS ester is a highly efficient cyclic alkyne click reagent. TMTHSI succinimide NHS ester has the primary activity to rapidly undergo strain-promoted cycloaddition reactions with azides. TMTHSI succinimide NHS ester is easily functionalized and can be linked to a variety of small molecules and (peptides, nucleic acids) biologics via a variety of linkers .
|
-
- HY-136964
-
-
- HY-D0893
-
|
|
Fluorescent Dye
|
Others
|
|
NSP-SA-NHS is an acridinium ester that can be used for chemiluminescent immunoassay. A rapid and sensitive chemiluminescent immunoassay of Bisphenol A (BPA) with NSP-SA-NHS-labeled has been developed .
|
-
- HY-156491
-
|
|
ADC Linkers
|
Cancer
|
|
Me-Tet-PEG9-NHS is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-140067A
-
|
|
PROTAC Linkers
|
Cancer
|
|
endo-BCN-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. endo-BCN-PEG2-NHS ester contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-156476
-
|
|
ADC Linkers
|
Cancer
|
|
Me-Tet-PEG2-NHS is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156313
-
|
|
ADC Linkers
|
Cancer
|
|
Me-Tet-PEG4-NHS is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-156490
-
|
|
ADC Linkers
|
Cancer
|
|
Me-Tet-PEG5-NHS is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-155500
-
|
|
Fluorescent Dye
|
Others
|
|
Digoxigenin NHS ester is an activated ester which readily reacts with amino groups under mild conditions, attaching the Digoxigenin (HY-B1025) moiety to proteins or amino-. Digoxigenin NHS ester can be used to label proteins and oligonucleotides .
|
-
- HY-D3271
-
|
|
Fluorescent Dye
|
Others
|
|
IR 750 NHS ester is a near-infrared fluorescent dye composed of IRDye 750 near-infrared fluorophore and NHS ester reactive group. IR 750 NHS ester can be applied to fluorescent labeling, imaging and detection.
|
-
- HY-D1239
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY R6G NHS ester is a borondipyrromethene dye. BODIPY R6G NHS ester can be conjugated with proteins. BODIPY R6G NHS ester can be used for intracellular traces .
|
-
- HY-140889
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG4-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140888
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-PEG2-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D2741
-
|
|
Fluorescent Dye
|
Others
|
|
MB 488 NHS ester is a fluroescent agent with a terminal NHS ester group. MB 488 NHS ester is a green fluorescent, very hydrophilic dye molecule that has a maximal absorption of 501 nm and emission at 524 nm. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-138756
-
|
|
PROTAC Linkers
|
Cancer
|
|
PC DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140070
-
|
|
PROTAC Linkers
|
Cancer
|
|
endo-BCN-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG8-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140276
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-NHCO-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG13-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140069
-
|
|
PROTAC Linkers
|
Cancer
|
|
endo-BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140275
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-NHCO-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140068
-
|
|
PROTAC Linkers
|
Cancer
|
|
endo-BCN-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG3-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133375
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-NHCO-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG2-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-126505
-
|
|
ADC Linkers
|
Cancer
|
|
Mal-PEG4-NHS ester is a non-cleavable ADC linker which links Quantum dots (QDs) with PEGylated liposomes .
|
-
- HY-133371
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-NHCO-C4-NHS ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-C4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130551
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG5-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D1119
-
|
|
Fluorescent Dye
|
Others
|
|
AF647-NHS ester is an analog of Alexa Fluor 647 (AF647). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: Protect from light .
|
-
- HY-W035129
-
|
|
Biochemical Assay Reagents
|
Others
|
|
endo-BCN-NHS carbonate is an elastin-like protein (ELP) modification reagent. endo-BCN-NHS carbonate can react with lysine residues in ELP to make ELP carry BCN groups, and then cross-link ELP through strain-promoted azide-alkyne cycloaddition (SPAAC) reaction. endo-BCN-NHS carbonate promotes hydrogel formation. endo-BCN-NHS carbonate is mainly used in cell encapsulation related research .
|
-
- HY-W040254
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-LC-LC-NHS is a biotinylation reagent that contains an NHS moiety, which can react efficiently with primary amino (-NH2). Biotin-LC-LC-NHS enables simple and efficient biotinylation of antibodies, proteins, and any other primary amine-containing biomolecules in solution. Biotin-LC-LC-NHS can be used to biotinylate small molecules such as Paclitaxel (HY-B0015) for use in binding site characterization.
|
-
- HY-174892
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG5-NHS ester is a heterobifunctional crosslinker as well as a polyethylene glycol-containing bioconjugation reagent. Biotin-PEG5-NHS ester is widely used in scientific research fields such as the construction of highly sensitive biosensors, the development of targeted drug delivery systems (e.g., liposome modification), immunofluorescence imaging, and protein affinity purification, and serves as an important tool for achieving precise labeling and functionalization of biomolecules .
|
-
- HY-403561
-
|
|
ADC Linkers
|
Others
|
|
2-MSP-C3-NHS ester is a linker that can be used in the synthesis of ADCs .
|
-
- HY-160072
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Drug Intermediate
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Cancer
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Fmoc-NH-PEG2-NHS ester is an intermediate used in the synthesis of E-selectin antagonists [1] .
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-
- HY-D0892
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Biochemical Assay Reagents
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Cancer
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|
NSP-DMAE-NHS is an acridinium ester-based signal amplifier that can act as a luminescent probe to effectively improve the detection performance of biosensors. NSP-DMAE-NHS preserves the biochemical activity of biomolecules during the conjugation process. NSP-DMAE-NHS has been successfully applied to label mouse anti-human PI3 monoclonal antibodies for chemiluminescent immunoassays, as well as for pre-competitive chemiluminescent immunochromatographic detection of TP53 fusion proteins. NSP-DMAE-NHS can be used in detection studies of cancer and related biomarkers .
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-
- HY-172309
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Fluorescent Dye
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Others
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|
UBQ-3 NHS Ester is a fluroescent agent with a terminal NHS ester group. UBQ-3 NHS Ester has a wide quenching range from 620-730 nm, which makes the compound useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with far-red to near-IR emitting dyes such as Cy5, Cy5.5, Alexa Fluor 633, 647, 700. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
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-
- HY-177502
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-
- HY-136048
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ADC Linkers
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Cancer
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|
Methylcyclopropene-PEG4-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-141358
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ADC Linkers
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Cancer
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|
SPDP-PEG36-NHS ester is a cleavable 36 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-W019793
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-
- HY-W800726
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Biochemical Assay Reagents
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Others
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|
BB1-NHS ester is amine reactive at pH 7-9 to form a stable, irreversible amide bond. It was used in a unique chemselective "unclickable' bioconjugation strategy to site specifically modify proteins.
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-
- HY-D3228
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-
- HY-W777012
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Fluorescent Dye
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Acridinium C2 NHS ester is a chemiluminescent label that is active for the development of protein and nucleic acid probes. Acridinium C2 NHS ester can be used in bioanalysis and diagnostics to provide highly sensitive detection solutions. Acridinium C2 NHS ester is widely used in medical research, especially in the monitoring and analysis of biomolecules.
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-
- HY-D1119C
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Fluorescent Dye
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Others
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AF647-NHS ester is an analogue of Alexa Fluor 647 (AF647), which has excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.) .
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-
- HY-W776820
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OXYL-1-NHS
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Biochemical Assay Reagents
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Others
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1-Oxyl-2,2,5,5-tetramethylpyrroline-3-carboxylate NHS ester (OXYL-1-NHS) is an active acylating agent that can be used to spin label proteins and aminoacylated RNA species .
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-
- HY-W440927
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Liposome
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Others
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Stearic acid-PEG2000-NHS is an amphiphatic PEG polymer which forms micelles in an aqueous solution for drug-loaded nanoparticles. The NHS ester is reactive with amine to form a stable amide bond. Reagent grade, for research purpose.
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-
- HY-140139
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ADC Linkers
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Cancer
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|
PC Alkyne-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC Alkyne-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-156323
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|
ADC Linkers
|
Cancer
|
|
BCN-exo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-exo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.
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-
- HY-156324
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|
|
ADC Linkers
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Cancer
|
|
BCN-exo-PEG8-NHS is an ADC Linker containing 8 PEG units. BCN-exo-PEG8-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.
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-
- HY-140756
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|
PROTAC Linkers
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Cancer
|
|
Azido-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG1-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140758
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|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG9-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-174894
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Biochemical Assay Reagents
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Others
|
|
Azido-PEG11-NHS ester is a PEG derivative that can be used for drug delivery and other research. Azido-PEG11-NHS ester is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group. It can also undergo ring strain driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
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-
- HY-140762
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PROTAC Linkers
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Cancer
|
|
Azido-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG24-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140761
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PROTAC Linkers
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Cancer
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|
Azido-PEG16-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG16-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-138463
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|
PROTAC Linkers
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Cancer
|
|
Azido-PEG36-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG36-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140764
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PROTAC Linkers
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Cancer
|
|
Azido-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140759
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PROTAC Linkers
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Cancer
|
|
Azido-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG10-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140760
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PROTAC Linkers
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Cancer
|
|
Azido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG12-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-138707
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|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG7-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG7-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-140757
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|
|
PROTAC Linkers
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Cancer
|
|
Azido-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-147287
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|
PSMA
Drug Intermediate
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Cancer
|
|
Glu-urea-Glu-NHS ester is an activated N-hydroxysuccinamide (NHS) ester of Glu-urea-Glu. Glu-urea-Glu-NHS ester can be used for synthesis of small-molecule prostate-specific membrane antigen (PSMA) inhibitors, imaging agents (such as PSMAi-PEG conjugates), and targeted drug delivery vehicles .
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-
- HY-42973
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ADC Linkers
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Cancer
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|
DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-141165
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|
PROTAC Linkers
|
Cancer
|
|
TCO-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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-
- HY-D3258
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Fluorescent Dye
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Others
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|
AF 660 NHS ester is a fluorescent dye AF 660 derivative exhibits high fluorescence quantum yield and high photostability. AF 660 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 668/698 nm).
|
-
- HY-D3257
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|
|
Fluorescent Dye
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Others
|
|
AF 546 NHS ester is a fluorescent dye AF 546 derivative exhibits high fluorescence quantum yield and high photostability. AF 546 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 554/570 nm).
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-
- HY-D3259
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|
|
Fluorescent Dye
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Others
|
|
AF 680 NHS ester is a fluorescent dye AF 680 derivative exhibits high fluorescence quantum yield and high photostability. AF 680 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 684/707 nm).
|
-
- HY-D3256
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|
|
Fluorescent Dye
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Others
|
|
AF 532 NHS ester is a fluorescent dye AF 532 derivative exhibits high fluorescence quantum yield and high photostability. AF 532 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 530/555 nm).
|
-
- HY-151742
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ADC Linkers
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Others
|
|
Norbornene-methyl-NHS is a norbornene-based antibody-drug conjugate linker (ADC Linker) bearing methyl and NHS ester functional groups, which can be used for specific antibody conjugation. Norbornene-methyl-NHS is also a click chemistry reagent containing a TCO group, acting as a dienophile for conjugation via the Diels-Alder reaction, namely the copper-free click reaction with tetrazine .
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-
- HY-172355
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Biochemical Assay Reagents
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Others
|
|
Azide-PEG-NHS (Mn 3500) is an azide PEG NHS ester that can be used for click chemistry reactions and can also be used to synthesize PEG hydrogels .
|
-
- HY-172355A
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Biochemical Assay Reagents
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Others
|
|
Azide-PEG-NHS (Mn 5000) is an azide PEG NHS ester that can be used for click chemistry reactions and can also be used to synthesize PEG hydrogels .
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-
- HY-D3272
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|
|
Fluorescent Dye
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Others
|
|
IR 680LT NHS ester is a fluorescent dye with an NHS ester moiety, which can be used to label antibodies, proteins, etc (Ex/Em = 675/694 nm) .
|
-
- HY-151835
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|
|
ADC Linkers
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Others
|
|
DBCO-PEG24-NHS ester is a click chemistry reagent. DBCO-PEG24-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .
|
-
- HY-157012
-
-
- HY-141169B
-
|
|
ADC Linkers
|
Cancer
|
|
(R)-TCO-PEG8-NHS ester is an ADC linker containing 8 PEG units. (R)-TCO-PEG8-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-140755
-
|
|
PROTAC Linkers
|
Cancer
|
|
Aeide-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Aeide-C1-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-153631
-
-
- HY-172354B
-
|
|
Biochemical Assay Reagents
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Others
|
|
Acrylate-PEG5000-NHS is a photosensitive PEG compound that can be cross-linked when exposed to ultraviolet light and is used to synthesize PEG hydrogels .
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-
- HY-172354A
-
|
|
Biochemical Assay Reagents
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Others
|
|
Acrylate-PEG3500-NHS is a photosensitive PEG compound that can be cross-linked when exposed to ultraviolet light and is used to synthesize PEG hydrogels .
|
-
- HY-D1615
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY 530/550 NHS ester can be used for the stain of protein. BODIPY 530/550 NHS ester can be used for fluorescence OIM (oblique illumination microscopic) image .
|
-
- HY-172354
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Acrylate-PEG2000-NHS is a photosensitive PEG compound that can be cross-linked when exposed to ultraviolet light and is used to synthesize PEG hydrogels .
|
-
- HY-164724
-
|
|
ADC Linkers
|
Cancer
|
|
Bis-PEG30-NHS ester is a non-claevable 30-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W040134
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141012
-
-
- HY-140746
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyloxy carbonyl-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140442
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-aminooxy-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141119
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138441
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG11-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141103
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-NMe-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138729
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141118
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W008879
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140977
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126880
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-NH-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140623
-
|
|
PROTAC Linkers
|
Cancer
|
|
Ald-Ph-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141120
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W040133
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138731
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138730
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-amido-PEG7-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-151827
-
|
|
ADC Linkers
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Others
|
|
DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .
|
-
- HY-W096079
-
|
|
ADC Linkers
|
Cancer
|
|
BCN-endo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-endo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
-
- HY-D0167
-
|
|
Fluorescent Dye
|
Others
|
|
NHS-5(6)Carboxyrhodamine is a dye used for fluorescence labeling applications, where accurate dye/protein ratios can be obtained under native conditions .
|
-
- HY-133584
-
|
|
ADC Linkers
|
Cancer
|
|
Bis-SS-C3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-D3263
-
|
|
Fluorescent Dye
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Others
|
|
IR 650 NHS ester is a far-red-fluorescent probe with NHS ester. NHS ester is the most popular amine-reactive group for labeling with the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. (Ex=651nm, Em=668 nm)
|
-
- HY-W156324
-
|
|
PROTAC Linkers
Liposome
|
Others
|
|
Biotin-PEGn-NHS ester is a biotin-labeled PROTAC linker, which belongs to the PEG class and can be used to synthesize PROTAC molecules. Biotin-PEGn-NHS ester can interact with free neutral avidin in solution and successfully target malignant glioma cells. Biotin-PEGn-NHS ester can also be grafted onto the amino group of GelMA to prepare biotin-modified functionalized hydrogel, gelatin methacryloyl (Bio-GelMA) .
|
-
- HY-D1872
-
|
|
Fluorescent Dye
|
Others
|
|
800CW NHS ester is a near-infrared fluorescent dye active ester that can conjugate with amine-containing small molecules, antibodies, peptides, and other substances to form fluorescent conjugates. 800CW NHS ester exhibits high fluorescence quantum yield and low non-specific binding properties. 800CW NHS ester can be used in biomedical research such as microbial infection imaging, tumor imaging, and biochemical detection .
|
-
- HY-185225
-
|
|
Drug Derivative
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Others
|
|
cis-Vaccenic acid NHS ester is an N-hydroxysuccinimide (NHS)-activated ester derivative of cis-vaccenic acid (HY-113427A) (C18:1 n-7), which is commonly used as a fatty acid labeling reagent or covalent modification reagent .
|
-
- HY-D1041
-
|
ICG-OSu
|
Fluorescent Dye
|
Cancer
|
|
ICG NHS ester (ICG-OSu) is a near-infrared fluorescent agent ICG derivative. ICG NHS ester is amine-reactive and has been widely used to design in vivo imaging probes .
|
-
- HY-N16296
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 NHS ester chloride is a fluorescent dye. Cy7.5 NHS ester chloride can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester chloride can be used for fluorescent imaging study (Ex/Em = 780/820 nm) .
|
-
- HY-W591977
-
|
|
Biochemical Assay Reagents
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Others
|
|
Boc-5-aminopentanoic NHS ester is a linker containing an NHS ester and a t-Boc protected amine group. The t-Boc group can be deprotected under mild acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-141044
-
|
|
PROTAC Linkers
|
Cancer
|
|
Cy5-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-N15975
-
|
|
Biochemical Assay Reagents
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Others
|
|
12:0 N-Biotinyl fatty acid, NHS is a biotinylated lipid. 12:0 N-Biotinyl fatty acid, NHS contains NHS groups that react with ammonia to form ester bonds .
|
-
- HY-D2365
-
|
|
Fluorescent Dye
|
Others
|
|
QSY 21 NHS is a dark quencher and an efficient energy transfer acceptor for far-red and near-infrared fluorescent probes. QSY 21 NHS operates at a wavelength range of 540-750 nm and is commonly used in FRET applications. QSY 21 NHS does not fluoresce under normal conditions. The NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides and other amine-containing molecules. QSY 21 NHS can be conjugated with dendritic poly-L-lysine to achieve intramolecular quenching of Cy5 fluorescence .
|
-
- HY-W087028
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Biochemical Assay Reagents
CXCR
|
Cancer
|
|
NOTA-NHS ester is a chelating agent. NOTA-NHS ester can be coupled with T140 (HY-P4810) to produce NOTA-T140. NOTA-T140 can be radiolabeled with Al[ 18F]. The uptake of Al[ 18F]NOTA-T140 in tumors is correlated with the expression level of CXCR4. Al[ 18F]NOTA-T140 can be used in tumor PET imaging studies. NOTA-NHS ester can be used for fluorescent labeling .
|
-
- HY-182234
-
-
- HY-W190920
-
|
|
Biochemical Assay Reagents
|
Others
|
|
t-Butoxycarbonyl-PEG2-NHS ester has a t-Boc protecting group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
|
-
- HY-140341
-
|
|
PROTAC Linkers
|
Cancer
|
|
Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-174959H
-
-
- HY-174959C
-
-
- HY-W1048512C
-
-
- HY-W1048603D
-
-
- HY-174959B
-
-
- HY-174959
-
-
- HY-W1048603H
-
-
- HY-W1048512A
-
-
- HY-174959D
-
-
- HY-W1048603E
-
-
- HY-W1048603J
-
-
- HY-W1048603I
-
-
- HY-W1048603A
-
-
- HY-W1048512D
-
-
- HY-174959E
-
-
- HY-W800685
-
-
- HY-174959A
-
-
- HY-W1048512B
-
-
- HY-W1048603C
-
-
- HY-D2166
-
|
|
Fluorescent Dye
|
Others
|
|
AF 594 NHS ester is a derivative of the red fluorescent dye AF 594 with high fluorescence quantum yield and high photostability (Ex=594 nm, Em=615 nm). AF 594 NHS ester can form an ester bond by reacting the NHS group with ammonia, with maximum excitation wavelength of 594 nm .
|
-
- HY-141489
-
|
|
Biochemical Assay Reagents
Liposome
|
Neurological Disease
|
|
DSPE-PEG2000-Carboxy NHS sodium is a linker. DSPE-PEG2000-Carboxy NHS sodium enables conjugation of targeting peptides to lipid nanoparticles after their preparation. DSPE-PEG2000-Carboxy NHS sodium is applicable to the research of hereditary retinal degeneration .
|
-
- HY-126509
-
|
|
ADC Linkers
|
Cancer
|
|
Mal-amido-PEG10-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
-
- HY-126508
-
|
|
ADC Linkers
|
Cancer
|
|
Mal-amido-PEG10-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules
|
-
- HY-126507
-
|
|
ADC Linkers
|
Cancer
|
|
Mal-amido-PEG1-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules
|
-
- HY-140141
-
|
|
PROTAC Linkers
|
Cancer
|
|
PC Methyltetrazine-PEG4-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC Methyltetrazine-PEG4-NHS carbonate ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133479
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-C3-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D1691
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY-581/591 NHS ester is a bright, red fluorescent dye (excitation: 581 nm; emission: 591 nm). BODIPY-581/591 NHS ester can be used for the labeling of amine containing biomolecules .
|
-
- HY-128890A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOTA-NHS-ester (hexafluorophosphate TFA)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-NHS-ester (hexafluorophosphate TFA) can be used for conjugation of peptides and radionuclides.
|
-
- HY-111496
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Sulfo-NHS-SS-biotin sodium is a long-chain cleavable and cell-impermeant amine-reactive biotinylation reagent. Sulfo-NHS-SS-biotin sodium can be used for the labeling and purifying of cell-surface protein .
|
-
- HY-141169A
-
|
|
ADC Linkers
|
Cancer
|
|
(S)-TCO-PEG8-NHS ester is an ADC linker containing 8 PEG units. (S)-TCO-PEG8-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-D2746
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5 bis-NHS ester is a reactive cyanine dye containing NHS ester which can be used to label amine groups in peptides, proteins, and oligonucleotides.
|
-
- HY-140134
-
|
|
ADC Linkers
|
Cancer
|
|
PC Biotin-PEG3-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-151698
-
|
|
ADC Linkers
|
Others
|
|
TCO-NHS Ester axial is a click chemistry reagent that can be used as a building block in amine reactions. TCO-NHS Ester axial contains TCO groups, which can undergo inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-130107
-
|
|
ADC Linkers
|
Cancer
|
|
Ald-Ph-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC).
|
-
- HY-W405064
-
|
|
Liposome
|
Others
|
|
11-Mercaptoundecanoate-NHS is a lipid that can be used for the synthesis of Linker.
|
-
- HY-D1310
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-cyanine3.5 NHS ester tripotassium is a water-soluble cyanine dye that contains NHS ester groups and is amino-reactive.
|
-
- HY-140135
-
|
|
PROTAC Linkers
|
Cancer
|
|
PC-Biotin-PEG4-NHS carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140417
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140418
-
|
|
PROTAC Linkers
|
Cancer
|
|
t-Boc-Aminooxy-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135973
-
|
|
ADC Linkers
|
Cancer
|
|
BCN-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-SS-NHS is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-128890B
-
|
|
ADC Linkers
Biochemical Assay Reagents
|
Cancer
|
|
DOTA-NHS-ester (TFA) is used as a linker for affibody molecules, and it can be employed in small animal positron emission tomography (PET), single photon emission computed tomography (SPECT), and CT scanning. DOTA-NHS-ester can be used to label radiotracers or imaging probes for tumor detection .
|
-
- HY-123687
-
|
|
ADC Linkers
|
Cancer
|
|
DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-126517
-
|
|
ADC Linkers
|
Cancer
|
|
Cyclooctyne-O-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Cyclooctyne-O-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133536
-
|
PA-JF549-NHS
|
Fluorescent Dye
|
Others
|
|
PA Janelia Fluor 549, SE (PA-JF549-NHS) is a bright photoactivatable fluorophore of JF549,SE (JF549,NHS). JF549,SE (JF549,NHS) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm .
|
-
- HY-D1993
-
|
|
Fluorescent Dye
HIV
|
Infection
|
|
ATTO 647 NHS ester is a fluorescent label targeting free amino groups. ATTO 647 NHS ester can undergo a nucleophilic reaction with the free amino groups of EF-C peptide via its activated carboxylic acid group to form a stable covalent conjugate. ATTO 647 NHS ester-labeled nanofibers not only retain retroviral transduction-enhancing activity but also maintain stable fluorescent signals in both buffer and cell culture systems. ATTO 647 NHS ester is suitable for detection applications including fluorescence spectroscopy, microscopy and flow cytometry. ATTO 647 NHS ester has been used in studies related to HIV-1 infection .
|
-
- HY-D2046
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 532 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 NHS ester is an NHS ester derivative of ATTO 532 that can be used to label proteins or antibodies.
|
-
- HY-D1957
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 633 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 633 NHS ester is an NHS ester derivative of ATTO 633 that can be used to label proteins or antibodies.
|
-
- HY-D2019
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 550 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 NHS ester is an NHS ester derivative of ATTO 550 that can be used to label proteins or antibodies.
|
-
- HY-153524
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 425 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 425 NHS ester is an NHS ester derivative of ATTO 425 that can be used to label proteins or antibodies.
|
-
- HY-D1929
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 594 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 594 NHS ester is an NHS ester derivative of ATTO 594 that can be used to label proteins or antibodies.
|
-
- HY-D1959
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 565 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 NHS ester is an NHS ester derivative of ATTO 565 that can be used to label proteins or antibodies.
|
-
- HY-D2058
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 700 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 700 NHS ester is an NHS ester derivative of ATTO 700 that can be used to label proteins or antibodies.
|
-
- HY-D2026
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 514 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 514 NHS ester is an NHS ester derivative of ATTO 514 that can be used to label proteins or antibodies.
|
-
- HY-D1999
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 665 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 665 NHS ester is an NHS ester derivative of ATTO 665 that can be used to label proteins or antibodies.
|
-
- HY-D1932
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 590 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 NHS ester is an NHS ester derivative of ATTO 590 that can be used to label proteins or antibodies.
|
-
- HY-D2073
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 680 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 680 NHS ester is an NHS ester derivative of ATTO 680 that can be used to label proteins or antibodies.
|
-
- HY-D1917
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 390 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 390 NHS ester is an NHS ester derivative of ATTO 390 that can be used to label proteins or antibodies.
|
-
- HY-D2001
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 488 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 NHS ester is an NHS ester derivative of ATTO 488 that can be used to label proteins or antibodies.
|
-
- HY-D1935
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 465 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 465 NHS ester is an NHS ester derivative of ATTO 465 that can be used to label proteins or antibodies.
|
-
- HY-147117
-
-
- HY-172286
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7 NHS ester is a fluorescent dye that can be used for fluorescent imaging study.
|
-
- HY-174264
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG2000-NHS is a polyethylene glycol lipid with a molecular weight of 2000, which can be used to construct novel drug delivery systems that confer mucoadhesive and cell-targeting capabilities to lipid nanoparticles .
|
-
- HY-136033
-
|
|
ADC Linkers
|
Cancer
|
|
Methyltetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-126908
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-130283
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136032
-
|
|
ADC Linkers
|
Cancer
|
|
Tetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-W879040
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Sulfo-DBCO-NHS ester is a click chemistry reagent containing an azide group. The DBCO group is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. NHS ester can bind to amino acids or other molecules containing amino groups .
|
-
- HY-D1315
-
-
- HY-D2238
-
-
- HY-133405
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-O-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126523
-
|
|
ADC Linkers
|
Cancer
|
|
N3-C5-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-126521
-
|
|
ADC Linkers
|
Cancer
|
|
N3-C3-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-126522
-
|
|
ADC Linkers
|
Cancer
|
|
N3-C4-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-126520
-
|
|
ADC Linkers
|
Cancer
|
|
N3-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W591479
-
|
|
ADC Linkers
|
Cancer
|
|
MC-Val-Ala-NHS ester is a cleavable ADC linker with a malimide group and an NHS ester group. The Val-Ala linkers can be cleaved by Cathepsin B. Maleimide group is reactive toward thiol groups. MC is reactive with thiol moieties. The NHS ester is able to react specifically and efficiently with amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond.
|
-
- HY-D1119A
-
|
|
Fluorescent Dye
|
Others
|
|
AF647-NHS ester tripotassium is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
|
-
- HY-D1119B
-
|
|
Fluorescent Dye
|
Others
|
|
AF647-NHS ester (trisodium) is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
|
-
- HY-181847
-
|
|
Drug Derivative
|
Others
|
|
JQ-1 (carboxylic acid)-NHS is an ester derivative of (+)-JQ-1 (HY-13030). JQ-1 (carboxylic acid)-NHS serves as a negative control .
|
-
- HY-135414A
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5 NHS ester bromide is a active compound, can be used to label amino groups in peptides, proteins, and oligonucleotides. Cyanine5 NHS ester bromide is a cyanine dye, fluorescence-labeling neurotensin (8-13) via arginine residues .
|
-
- HY-W250735
-
|
|
Biochemical Assay Reagents
|
Others
|
|
NHS-PEG4-biotinidase resistant biotin is a biotinylation reagent with a terminal NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-D1568A
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7.5 NHS ester tripotassium is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester tripotassium contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester tripotassium can be used for the research of NIR imaging applications .
|
-
- HY-141122
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-PEG4-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138414
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetic-PEG1-CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140011
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-C2-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141386
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bromoacetamido-PEG2-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-115524
-
|
|
ADC Linkers
|
Cancer
|
|
DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry[1]. DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-W441015A
-
|
|
Liposome
|
Others
|
|
DSPE-m-PEG3400-NHS is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine .
|
-
- HY-151698A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(S,E)-TCO-NHS Ester is a Click Amino Acid that can be used to label amine-containing compounds or biomolecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
|
-
- HY-151698B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(R,E)-TCO-NHS Ester is a Click Amino Acid that can be used to label amine-containing compounds or biomolecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
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-
- HY-185142
-
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Ligands for E3 Ligase
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Cancer
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|
The (S,R,S)-AHPC-Me-C8-NHS ester is an E3 ubiquitin ligase VHL ligand, used to recruit the VHL protein. The (S,R,S)-AHPC-Me-C8-NHS ester can be linked to the target protein ligand through a linker to form a PROTAC.
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-
- HY-W019795
-
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PROTAC Linkers
|
Cancer
|
|
m-PEGn-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-140025
-
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ADC Linkers
|
Cancer
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|
Propargyl-PEG4-CH2CO2-NHS (compound P-7) is a PEG derivative containing a propargyl group and an NHS group. Propargyl-PEG4-CH2CO2-NHS is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG4-CH2CO2-NHS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
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-
- HY-140142
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PROTAC Linkers
|
Cancer
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|
PC Azido-PEG11-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC Azido-PEG11-NHS carbonate ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-110210
-
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BODIPY FL,SE
|
Fluorescent Dye
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Others
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|
BODIPY FL NHS ester (BODIPY FL, SE) is a cell membranes-penatrable amine-reactive fluorescent probe. The maximum excitation/emission wavelength of the BODIPY-FL NHS ester are 502/511 nm, respectively. BODIPY-FL NHS ester has high stability and is insensitive to the polarity, pH and type of solvent, and can maintain stable fluorescence properties under different environmental conditions. BODIPY-FL NHS ester can be used for the synthesis of protease substrates, live cell imaging, protein labeling and immunoassay .
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-
- HY-D3325
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Fluorescent Dye
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Others
|
|
AF 700 NHS ester is a fluorescent dye AF 700 derivative exhibits high fluorescence quantum yield and high photostability. AF 700 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 702/723 nm).
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-
- HY-D3326
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Fluorescent Dye
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Others
|
|
AF 750 NHS ester is a fluorescent dye AF 750 derivative exhibits high fluorescence quantum yield and high photostability. AF 750 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 753/782 nm).
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-
- HY-D3323
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Fluorescent Dye
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Others
|
|
AF 350 NHS ester is a fluorescent dye AF 350 derivative exhibits high fluorescence quantum yield and high photostability. AF 350 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 346/445 nm) .
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-
- HY-149117
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Fluorescent Dye
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Others
|
|
AF430 NHS ester is an AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF430 NHS ester can be uesd for the labeling of amino-groups in peptides, proteins, and oligonucleotides. To achieve specific coupling of dye labels and biomolecules .
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-
- HY-W441014C
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Biochemical Assay Reagents
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Others
|
|
DSPE-PEG40000-NHS ammonium is one of the most commonly used reactive phospholipids for coupling antibodies, proteins, peptides or other substrates to the surface of liposomes and other lipid PEG nanoparticles .
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-
- HY-W441014B
-
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Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG20000-NHS ammonium is one of the most commonly used reactive phospholipids for coupling antibodies, proteins, peptides or other substrates to the surface of liposomes and other lipid PEG nanoparticles .
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-
- HY-W441014A
-
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Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG10000-NHS ammonium is one of the most commonly used reactive phospholipids for coupling antibodies, proteins, peptides or other substrates to the surface of liposomes and other lipid PEG nanoparticles .
|
-
- HY-136134
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ADC Linkers
|
Cancer
|
|
SS-bis-amino-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130091
-
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|
ADC Linkers
|
Cancer
|
|
NHPI-PEG4-C2-NHS ester is an ADC Linker, which can be used to synthesize antibody-drug conjugates (ADCs) .
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-
- HY-135959
-
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|
PROTAC Linkers
|
Cancer
|
|
DBCO-NH-PEG7-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NH-PEG7-C2-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-160773A
-
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Biochemical Assay Reagents
|
Others
|
|
DBCO-C3-amide-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-C3-amide-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
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-
- HY-D2761
-
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|
Fluorescent Dye
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Others
|
|
DY-680-NHS ester is an amine reactive hydrophilic fluorochrome. It can be conjugated to an antibody with higher D/P ratio without causing fluorescence quenching and conjugate precipitation, and it is widely used in applications including western blotting, microscopy, flow cytometry, and cell-based assays. The spectrum has an excitation of 690nm and emission at 709nm.
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-
- HY-140129
-
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|
ADC Linkers
|
Cancer
|
|
NHS-SS-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-141268
-
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|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-Sulfo-NHS ester (sodium) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
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-
- HY-130095
-
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|
ADC Linkers
|
Cancer
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|
NHPI-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
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-
- HY-133579
-
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|
ADC Linkers
|
Cancer
|
|
Ald-Ph-amido-PEG3-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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-
- HY-130093
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|
ADC Linkers
|
Cancer
|
|
NHPI-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
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-
- HY-134620
-
|
|
Fluorescent Dye
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Others
|
|
Cyanine 5 NHS ester tetrafluoroborate (Compound Cy5) is a cyanine dye that is used to in fluorescence detection of macromolecules. Cyanine 5 NHS ester tetrafluoroborate exhibits an excitation wavelength of 638 nm .
|
-
- HY-130390
-
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|
PROTAC Linkers
|
Cancer
|
|
Propargyl-PEG4-O-C1-NHS ester (compound 8) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-O-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-W800669
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PROTAC Linkers
|
Cancer
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|
(S, R, S)-AHPC-PEG2-NHS ester is a synthetic PROTAC linker that incorporatess an E3 ligase ligand with a PEG linker to empower PROTAC medicine chemistry. NHS ester is reactive with amine moiety. The hydrophilic PEG spacer increases its aqueous solubility.
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-
- HY-140767
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PROTAC Linkers
|
Cancer
|
|
Azido-PEG8-C1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-C1-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-W848699
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|
Fluorescent Dye
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Others
|
|
FAM NHS ester, 6-isomer is a hydrophilic fluorophore. The NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond.
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-
- HY-120773
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|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG3-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126881
-
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|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG2-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D1389
-
|
Sulfo-Cyanine5.5 NHS ester tripotassium
|
Fluorescent Dye
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Others
|
Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging .
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-
- HY-D2001A
-
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|
Fluorescent Dye
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Others
|
|
TTO 488 NHS ester TEA is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. TTO 488 NHS ester TEA is an NHS ester derivative of ATTO 488 that can be used to label proteins or antibodies.
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-
- HY-140067
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|
PROTAC Linkers
|
Cancer
|
|
endo-BCN-PEG2-C2-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-135414
-
|
|
Fluorescent Dye
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Others
|
|
Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .
|
-
- HY-148840
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|
Biochemical Assay Reagents
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Others
|
|
Sulfo DBCO-PEG3-NHS ester is a click chemistry reagent containing an azide group. Sulfo DBCO-PEG3-NHS ester is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO group is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain and sulfo group increase water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only .
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-
- HY-133581
-
|
|
ADC Linkers
|
Cancer
|
|
Mal-PEG3-C1-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-130931
-
|
|
ADC Linkers
|
Cancer
|
|
Propargyl-NH-PEG3-C2-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-NH-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-133539
-
|
|
ADC Linkers
|
Cancer
|
|
Propargyl-C8-amido-PEG2-NHS ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-C8-amido-PEG2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-W800828
-
|
|
Biochemical Assay Reagents
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Others
|
|
Iodoacetamido-PEG3-NHS ester is a PEG reagent containing an Iodoacetamide group and a Boc-protected amino group. The iodoacetamide group is an alkylating agent that can be used to bind covalently with the thiol group. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-141336
-
|
DL-α-Lipoic acid-NHS
|
PROTAC Linkers
|
Cancer
|
|
α-Lipoic acid-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126381
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-PEG5-C2-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-135029
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-N-PEG3-CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141116
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-N-PEG1-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141115
-
|
|
PROTAC Linkers
|
Cancer
|
|
Mal-NO2-Ph-PEG12-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W190948
-
|
|
Biochemical Assay Reagents
|
Others
|
|
10-(tert-Butoxy)-10-oxodecanoic NHS ester has a t-butyl ester group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond.
|
-
- HY-W190906
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-(tert-Butoxy)-6-oxohexanoic NHS ester has a t-butyl ester group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond.
|
-
- HY-115545
-
|
|
ADC Linkers
|
Cancer
|
|
DBCO-NHS ester 3 (Compound 12) is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 3 is a derivative of Dibenzylcyclooctyne (DBCO) obtained by activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC) . DBCO-NHS ester 3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-W440928
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG3400-NHS is a phospholipid polyPEG which can self-assemble in water to form lipid bilayer. The polymer can be used to prepare liposomes as drug carrier to deliver nutrients/therpeutic agents, such as mRNA or DNA.
|
-
- HY-W190937
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PC Azido-PEG3-NHS carbonate ester is a photocleavable linker. It can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-W591424
-
|
mPEG2000-SC; mPEG2000-Succinimidyl ester
|
Biochemical Assay Reagents
MMP
|
Cancer
|
|
m-PEG2000-NHS ester (mPEG2000-SC) is a reagent with both cell adhesion inhibition and peptide conjugation functions. The NHS ester group of m-PEG2000-NHS ester forms stable amide bonds with primary amine-containing molecules (e.g., the N-terminus of MMP-2-cleavable octapeptide) to generate mPEG-peptide intermediates for liposome surface modification. When m-PEG2000-NHS ester is immobilized on a cystamine-modified gold surface, it can construct an in vitro model for cell adhesion kinetic studies, and higher PEG density and thicker layers correlate with lower cell adhesion rates. m-PEG2000-NHS ester can synthesize MMP-2-responsive PEGylated lipid conjugates to achieve MMP-triggered dePEGylation in the tumor microenvironment. m-PEG2000-NHS ester can be used in studies related to colon cancer and other conditions .
|
-
- HY-D1352
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cyanine7 NHS ester potassium is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
|
-
- HY-154802
-
|
|
ADC Linkers
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
TCO-GK-PEG4-NHS ester is an ADC Linker, and can be used for synthesis of [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d. [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d binds with high affinity and immunoreactivity to HER2 . TCO-GK-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-139326
-
-
- HY-186069
-
|
|
Biochemical Assay Reagents
|
Others
|
|
NHS-Phosphine is an amine-reactive compound that can be used to derivatize primary amines of proteins or amine-coated polymer surfaces for ligation to azide-tagged molecules .
|
-
- HY-141117
-
|
|
PROTAC Linkers
|
Cancer
|
|
Boc-NH-PEG2-C2-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W800683
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Azide-TFP-Amide-SS-Sulfo-NHS consists of an aryl azide, a cleavable disulfide bond, and an NHS ester. The aryl azide can be photo-activated with UV light (250 to 350 nm) for conjugation with biomolecules. Fluoro helps to stabilize the free radical intermediate. The NHS ester reacts with amines. The disulfide bond can be cleaved by reducing agents.
|
-
- HY-RS09290
-
|
|
Small Interfering RNA (siRNA)
|
Others
|
|
NHS Human Pre-designed siRNA Set A contains three designed siRNAs for NHS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
|
-
NHS Human Pre-designed siRNA Set A
NHS Human Pre-designed siRNA Set A
- HY-136157
-
|
|
ADC Linkers
|
Cancer
|
|
Py-ds-dmBut-amido-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-RS22963
-
|
|
Small Interfering RNA (siRNA)
|
Others
|
|
Nhs Rat Pre-designed siRNA Set A contains three designed siRNAs for Nhs gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
|
-
Nhs Rat Pre-designed siRNA Set A
Nhs Rat Pre-designed siRNA Set A
- HY-RS16532
-
|
|
Small Interfering RNA (siRNA)
|
Others
|
|
Nhs Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nhs gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
|
-
Nhs Mouse Pre-designed siRNA Set A
Nhs Mouse Pre-designed siRNA Set A
- HY-140557
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG3-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140558
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Boc-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140583
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Desthiobiotin-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140572
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Mal-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140571
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-Mal-N-bis(PEG2-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-DY1072
-
|
ICG-OSu (solution)
|
Fluorescent Dye
|
Cancer
|
ICG NHS ester (ICG-OSu) (solution) is a near-infrared fluorescent agent ICG derivative. ICG NHS ester is amine-reactive and has been widely used to design in vivo imaging probes .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-160408
-
|
|
ADC Linkers
|
Cancer
|
|
Mal-GGG-Bal-NHS ester is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-D2175
-
|
|
Fluorescent Dye
|
Others
|
|
AF 555 NHS ester is a bright, orange-red fluorescence probe. AF 555 NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules (Ex/Em = 552/566 nm) .
|
-
- HY-W040113
-
-
- HY-W544595
-
-
- HY-148840A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Sulfo DBCO-PEG3-NHS ester TEA is a click chemistry reagent containing an azide group. Sulfo DBCO-PEG3-NHS ester (TEA) is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO group is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain and sulfo group increase water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only .
|
-
- HY-D1730A
-
|
|
Fluorescent Dye
|
Others
|
|
AF488 NHS ester TEA is an amine specific fluorescence probe (λem=525 nm=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
|
-
- HY-185226
-
|
|
Drug Metabolite
|
Cancer
|
|
γ-Linolenic acid NHS ester is a lipid metabolite of γ-Linolenic acid (GLA) (HY-N7140), which can serve as a synthetic intermediate or probe labeling reagent for the preparation of GLA conjugates. In practical applications, γ-Linolenic acid NHS ester can be conjugated with taxanes and polysaccharides to form dual-type conjugates for drug delivery purposes .
|
-
- HY-131326
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
DOTA-tris(tBu)ester NHS ester is a bifunctional precursor to a DOTA-based chelating agent. DOTA-tris(tBu)ester NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules, and upon deprotection forms stable complexes with metal ions for applications in molecular imaging .
|
-
- HY-135415
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5.5 NHS ester chloride is a reactive dye for the labeling of proteins, and antibodies and small molecular compounds .
|
-
- HY-140138
-
|
|
ADC Linkers
|
Cancer
|
|
PC SPDP-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140140
-
|
|
ADC Linkers
|
Cancer
|
|
PC Mal-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-164085
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Azide-C3-NHCO-C3-NHS ester is utilized as a linker in chemical synthesis, especially when rapid and specific ligation via click chemistry is required .
|
-
- HY-W190908
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Desthiobiotin-PEG3-NHS ester is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd = 1011 vs. 1015 M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin.
|
-
- HY-130106
-
|
|
ADC Linkers
|
Cancer
|
|
Ald-Ph-amido-PEG1-C2-NHS ester is a nonclaevable 1-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
- HY-130104
-
|
|
ADC Linkers
|
Cancer
|
|
Ald-Ph-amido-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
- HY-130101
-
|
|
ADC Linkers
|
Cancer
|
|
Ald-Ph-amido-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC).
|
-
- HY-140700
-
|
mPEG20000-SC; mPEG20000-Succinimidyl ester
|
PROTAC Linkers
|
Cancer
|
|
m-PEG20000-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140699
-
|
mPEG10000-SC; mPEG10000-Succinimidyl ester
|
PROTAC Linkers
|
Cancer
|
|
m-PEG10000-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140698
-
|
mPEG5000-SC; mPEG5000-Succinimidyl ester
|
PROTAC Linkers
|
Cancer
|
|
m-PEG5000-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-135414B
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .
|
-
- HY-130312
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W1052510
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N3-PEG2-CH2CO2-NHS is a PEG derivative containing an azide group and an NHS ester. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-140582
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-D2367
-
|
N-Hydroxysuccinimidyl rhodamine B ester
|
Fluorescent Dye
|
Others
|
|
Rhodamine B NHS ester (N-Hydroxysuccinimidyl rhodamine B ester) is an amine-reactive fluorescent probe (λex/λem: 564/589 nm, respectively). Rhodamine B NHS ester could react with Glycine (HY-Y0966) .
|
-
- HY-133412
-
|
|
ADC Linkers
|
Cancer
|
|
DBCO-NHCO-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133413
-
|
|
ADC Linkers
|
Cancer
|
|
DBCO-CONH-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-CONH-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-D2494
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy7 bis-NHS ester is a derivative of Cy7 (HY-D0825) dye containing sulfonate ions. Sulfo Cy7 bis-NHS ester can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-D2486
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy3 bis NHS ester is a derivative of Cy3 (HY-D0822) dye containing sulfonate ions. Sulfo Cy3 bis NHS ester can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-W143136
-
-
- HY-130436
-
|
|
PROTAC Linkers
|
Cancer
|
|
Acid-C2-PEG4-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130077
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-PEG1-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D2157
-
|
Coumarin 343-aminohexanoic acid-NHS ester
|
Fluorescent Dye
|
Others
|
|
Coumarin 343 X NHS ester is a homologue of Coumarin 343 (HY-W267364). Coumarin 343 is a hydrophilic fluorescent probe for use in microfluids.
|
-
- HY-139325
-
|
|
Drug-Linker Conjugates for ADC
|
Others
|
|
NHS-Modified MMAF (WO2012143499A2, intermediat 210) is an intermediate which can be used for producing the anti-mesothelin binder-agent conjugates (ADCs) .
|
-
- HY-150015
-
|
|
DNA/RNA Synthesis
|
Cancer
|
|
4,5'-Dimethylangelicin-NHS is a modified 4,5'-Dimethylangelicin containing an NHS. 4,5'-Dimethylangelicin is an angular furocoumarin with photochemical and photosensitizing properties. 4,5'-Dimethylangelicin can inhibit the DNA and RNA syntheses in Ehrlich ascites tumor cells alter irradiation at 365 nm. 4,5'-Dimethylangelicin has potential as a photochemotherapy agent .
|
-
- HY-D1352A
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cyanine7 NHS ester (TEA) is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester (TEA) reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
|
-
- HY-W190737
-
|
|
Biochemical Assay Reagents
|
|
|
NHS-SS-dPEG4-biotin (cleavable) is a biodegradable crosslinker with efficient bioconjugation activity. NHS-SS-dPEG4-biotin (cleavable) can effectively connect biomolecules, optimize the efficiency of biolabeling, and be used in targeted compound delivery systems. NHS-SS-dPEG4-biotin (cleavable) can also play an important role in protein engineering and fluorescence imaging.
|
-
- HY-126528
-
|
|
ADC Linkers
|
Cancer
|
|
N3-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-126526
-
|
|
ADC Linkers
|
Cancer
|
|
N3-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG2-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130109
-
|
|
ADC Linkers
|
Cancer
|
|
N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D0823
-
CY3-SE
1 Publications Verification
Sulfo-Cy3 NHS ester; Sulfo Cyanine3 NHS ester
|
Fluorescent Dye
|
Others
|
|
Cy3-SE (Sulfo-Cy3 NHS ester; Sulfo Cyanine3 NHS ester) is a sulfonated cyanine dye-derived fluorescent labeling reagent with λex of about 515 nm and λem of about 568 nm. Cy3-SE can interact with the π-π stacking of biomolecules (e.g., nucleoside monophosphates, proteins), inhibiting the photoisomerization process and increasing the fluorescence quantum yield and lifetime .
|
-
- HY-141047
-
|
|
PROTAC Linkers
|
Cancer
|
|
Bis-(N,N'-PEG4-NHS ester)-Cy5 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130490
-
|
|
PROTAC Linkers
|
Cancer
|
|
Biotin-bis-amido-SS-NHS is an Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-140585
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-DBCO-N-bis(PEG2-C2-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-DBCO-N-bis(PEG2-C2-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-139325A
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
NHS-Modified MMAF (intermediat 210) TFA is an intermediate which can be used for producing the anti-mesothelin binder-agent conjugates (ADCs) .
|
-
- HY-140766
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138350
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG10-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG10-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D2062
-
|
|
Fluorescent Dye
Integrin
|
Cancer
|
|
ATTO 740 NHS ester is a near-infrared fluorescent dye and a multimodal fluorescence/photoacoustic contrast agent with excellent near-infrared emission properties and extremely high photostability. The photoacoustic signal of ATTO 740 NHS ester shows no significant decrease after continuous irradiation with a 750 nm laser for 30 min, making it suitable for in vivo fluorescence imaging and photoacoustic contrast imaging. When conjugated with the cystine knot peptide R01, ATTO 740 NHS ester enables precise detection of integrin αvβ6-positive cells and tumors in nude mouse xenograft models .
|
-
- HY-W800668
-
|
|
PROTAC Linkers
|
Cancer
|
|
(S, R, S)-AHPC-PEG4-NHS ester is a PROTAC linker that incorporatess an E3 ligase ligand with a PEG4 spacer to empower PROTAC medicine chemistry. It is is reactive with amine molecule. PEG4 arm increases the molecule's solubility.
|
-
- HY-133431
-
|
|
ADC Linkers
|
Cancer
|
|
DBCO-PEG3-SS-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG3-SS-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-155909A
-
|
mPEG1000-SC; mPEG1000-Succinimidyl ester
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG1000-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-155909C
-
|
mPEG350-SC; mPEG350-Succinimidyl ester
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG350-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-155909B
-
|
mPEG550-SC; mPEG550-Succinimidyl ester
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG550-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-155909
-
|
mPEG3400-SC; mPEG3400-Succinimidyl ester
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG3400-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-135415A
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5.5 NHS ester chloride TEA is a reactive dye for the labeling of proteins, and antibodies and small molecular compounds .
|
-
- HY-140102
-
|
|
ADC Linkers
|
Cancer
|
|
Azidoethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azidoethyl-SS-propionic NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-167290
-
-
- HY-140763
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG1-CH2CO2-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG1-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133466
-
|
|
ADC Linkers
|
Cancer
|
|
Methyltetrazine-PEG4-SS-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-SS-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136040
-
|
|
ADC Linkers
|
Cancer
|
|
Tetrazine-PEG4-SS-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-W440926
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG1000-NHS is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond.
|
-
- HY-140765
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG4-NHS-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-NHS-ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-141113
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG4-O-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141084
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fluorescein-PEG6-bis-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141172A
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG2-Sulfo-NHS ester sodium is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141111
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG8-ethoxycarbonyl--NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-164862
-
|
|
PROTAC Linkers
|
Others
|
|
N-(NHS ester-PEG2)-N-bis(PEG3-azide) is a PEG linker with an NHS ester group and two terminal azide groups. N-(NHS ester-PEG2)-N-bis(PEG3-azide) can be utilized in Click Chemistry .
|
-
- HY-44149
-
|
|
ADC Linkers
|
Cancer
|
|
m-C-tri(CH2-PEG1-NHS ester) is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-118112
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-N-Maleimidobenzoicacid-NHS is a PEG linker that finds utility in bioconjugation endeavors and protein labeling ventures. Specifically designed for selective reaction with thiol groups, the maleimide group establishes covalent linkages, thereby facilitating the coupling of proteins, peptides, or diverse molecules to thiol-bearing biomolecules. The NHS ester is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic conditions to form a covalent bond.
|
-
- HY-126514
-
|
|
ADC Linkers
|
Cancer
|
|
Propargyl-O-C1-amido-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-O-C1-amido-PEG2-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-126515
-
|
|
ADC Linkers
|
Cancer
|
|
Propargyl-O-C1-amido-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-O-C1-amido-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-126524
-
|
|
ADC Linkers
|
Cancer
|
|
N3-Ph-NHS ester (compound 133) is an organic synthesis intermediate and ADC linker used for the synthesis of antibody-drug conjugate (ADC) molecules .
|
-
- HY-140680
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG20000-Lys-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140681
-
|
|
PROTAC Linkers
|
Cancer
|
|
m-PEG40000-Lys-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140560
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140561
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140559
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-172536
-
|
mPEG30000-SC; mPEG30000-Succinimidyl ester
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG30000-NHS ester (mPEG30000-SC) can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects .
|
-
- HY-D2459
-
|
|
Fluorescent Dye
|
Cancer
|
|
Alexa Fluor 430 NHS ester is a compound that couples green fluorescent dye Alexa Fluor 430 to a protein or antibody. Alexa Fluor 430 is used for the generation of stable signals in imaging and flow cytometry. NHS ester can be used to label proteins, amine-modified oligonucleotides and other primary amines (R-NH2) containing amine molecules .
|
-
- HY-D3053
-
|
|
Fluorescent Dye
|
Others
|
|
5(6)-Rhodamine 6G NHS ester is a reactive ester fluorescent reagent based on Rhodamine 6G (HY-D0309). NHS ester is a highly reactive ester capable of covalently coupling with primary amine groups in molecules such as proteins, peptides, amino sugars, and nucleic acids to form stable amide bonds (Ex/Em = 526/547 nm).
|
-
- HY-D2444
-
|
|
Fluorescent Dye
|
Cancer
|
|
AF555 NHS is a red fluorescent dye with excellent fluorescence properties and light stability. The excitation wavelength is 556 nm and the emission wavelength is 571 nm, which can be used for protein labeling, antibody labeling, and cell imaging .
|
-
- HY-D0799A
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-NHS-LC-Biotin is an amine-reactive ester derivative of biotin and cannot pass the intact blood-retinal barrier. It can be used to assess vascular permeability of the brain and retinal vasculature.
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-
- HY-D0799
-
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Fluorescent Dye
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Others
|
|
Sulfo-NHS-LC-Biotin sodium is an amine-reactive ester derivative of biotin and cannot pass the intact blood-retinal barrier. It can be used to assess vascular permeability of the brain and retinal vasculature.
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-
- HY-W096149
-
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|
Biochemical Assay Reagents
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Others
|
|
exo-BCN-NHS carbonate carbonate contains BCN group. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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-
- HY-133583
-
|
|
ADC Linkers
|
Cancer
|
|
Propargyl-O-C1-amido-PEG3-C2-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-O-C1-amido-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-D1596B
-
|
(E)-Cy3.5 NHS ester chloride; (E)-Cy 3.5 chloride
|
Fluorescent Dye
|
Others
|
|
(E)-Cyanine 3.5 ((E)-Cy3.5 NHS ester) chloride is a cyanine dye functionalized with a N-hydroxysuccinimide (NHS) group. (E)-Cyanine 3.5 chloride contains NHS groups that react with ammonia to form ester bonds (Ex/Em = 586/612 nm).
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-
- HY-W998643
-
|
|
Fluorescent Dye
|
Others
|
|
6,8-Difluoro-7-hydroxy-4-methylcoumarin NHS Ester is a molecule with an excitation at 365 nm and emission at 460 nm. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
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-
- HY-D1983
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 620 NHS-Ester is an activated ester derivative of ATTO 620, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 620/642 nm.
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-
- HY-133544
-
|
|
ADC Linkers
|
Cancer
|
|
Mal-CO-PEG5- NHS ester is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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-
- HY-D1611
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY FL-C5 NHS Ester is a green-fluorescent dye that is reactive with primary amines on biomolecules such as peptides, proteins, modified nucleotides and biopolymers .
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-
- HY-D1979
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 725 NHS-Ester is an activated ester derivative of ATTO 725, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 728/751 nm.
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-
- HY-D1974
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|
Fluorescent Dye
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Others
|
|
ATTO 610 NHS-Ester is an activated ester derivative of ATTO 610, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 616/633 nm.
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-
- HY-151769
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ADC Linkers
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Others
|
|
TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent containing an azide group. TCO-PEG2-Sulfo-NHS ester is a PEG linker containing a TCO moiety and a sulfo-NHS ester moiety. The sulfo group makes this molecule soluble in waqueous buffer. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety. Reagent grade, for research use only . TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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-
- HY-140119
-
|
|
ADC Linkers
|
Cancer
|
|
Fmoc-NH-ethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W800659
-
|
|
ADC Linkers
|
Others
|
|
Boc-Gly-Gly-NHS ester can be used to selectively attach small molecules to specific amino acid residues on proteins, creating conjugates that can be used for a variety of applications in drug discovery and diagnostic assays.
|
-
- HY-140866
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D2773
-
|
|
Fluorescent Dye
|
Others
|
|
5-Carboxyrhodamine 110 NHS Ester is the nonsulfonated analog of the BP Fluor 488 dye. The amine-reactive 5(6)-Carboxyrhodamine 110 NHS Ester can be used to create bright and photostable green-fluorescent bioconjugates with excitation/emission maxima ~502/527 nm. For many applications, the dye is preferred over 5-(6)-carboxyfluorescein NHS ester or FITC because of its exceptional photostability and fluorescence insensitivity to pH (4-9).
Although the mixed isomers of Carboxyrhodamine 110 NHS Ester preferred, routinely used fluorescent dye for labeling proteins, peptides and nucleotides, purification of peptide and nucleotides labeled with 5(6) isomers might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer usually give better resolution in HPLC purification that is often required in the conjugation processes.
|
-
- HY-185569
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
DM21-L-G NHS ester is a toxin molecule-linker conjugate that can be used for the synthesis of ADCs, such as Opugotamig olatansine (HY-185427) .
|
-
- HY-D1849
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3B NHS ester is a fluorescent dye compound that is commonly used in biomarking and fluorescent labeling experiments, especially for labeling biomolecules containing amino functional groups (amine groups), such as proteins, antibodies or peptides.
|
-
- HY-138522
-
|
|
PROTAC Linkers
|
Cancer
|
|
NHS-bis-PEG2-amide-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-136158A
-
|
Sulfo-EMCS
|
PROTAC Linkers
|
Cancer
|
|
6-Maleimidocaproic acid sulfo-NHS (Sulfo-EMCS) sodium is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D1496
-
|
|
Fluorescent Dye
|
Others
|
|
Fluorescent Red Mega 485 NHS-ester is an amine conjugating fluorescent biolabel that can be used to label proteins .
|
-
- HY-140768
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG3-O-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-O-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W190952
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Bis-sulfone-PEG4-NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. The hydrophilic PEG spacer increases solubility in aqueous media.
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-
- HY-W800627
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Bis-sulfone-PEG8-NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. The hydrophilic PEG spacer increases solubility in aqueous media.
|
-
- HY-D1294
-
|
|
Fluorescent Dye
|
Cancer
|
|
SY-21 NHS ester is a QSY-21 analog. QSY-21 is a specific quencher against A647. QSY-21 labels polymer. QSY-21 can be used in colon cancer research .
|
-
- HY-141045
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141046
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-172290
-
|
|
ADC Linkers
|
Cancer
|
|
Benzyl N1-[PEG1-NHS] -N6-(t-Boc)-L-lysinate is a multifunctional ADC linker consisting of a terminal benzyl group, one PEG unit, an NHS ester, and a t-Boc-protected L-lysine, often used for bioconjugation and chemical modifications in R&D.
|
-
![Benzyl N1-[PEG1-NHS]-N6-(t-Boc)-L-lysinate](//file.medchemexpress.com/product_pic/hy-172290.gif)
- HY-141123
-
|
|
ADC Linkers
|
Cancer
|
|
SPDP-C6-Gly-Leu-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-133585
-
|
|
ADC Linkers
|
Cancer
|
|
Bis-SS-C3-sulfo-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-171491
-
|
|
Fluorescent Dye
|
Others
|
|
NSP-DMAE-HEG-Giu-NHS (Fig.18) is an activated labeling reagent containing acridine ester, and it is a key component of Cyclosporine A (HY-B0579) tracers .
|
-
- HY-136158
-
|
Sulfo-EMCS free acid
|
PROTAC Linkers
|
Cancer
|
|
6-Maleimidocaproic acid sulfo-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D2768
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 430 NHS Ester is a water-soluble, green-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The NHS ester (or succinimidyl ester) is the most popular amine reactive group for labeling the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. Proteins can be labeled with BP Fluor 430 NHS Ester at high molar ratios without significant self-quenching, leading to brighter conjugates and more sensitive detection.
|
-
- HY-148657
-
|
NHS-Methotrexate
|
Others
|
Inflammation/Immunology
Cancer
|
|
Aminopterin N-hydroxysuccinimide ester(NHS-methotrexate) is an irreversible
Methotrexate (HY-14519) influx carrier inhibitor. Aminopterin N-hydroxysuccinimide ester can be used for the research of rheumatoid arthritis and a number of cancers (such as acute lymphoblastic leukemia) .
|
-
- HY-W105423
-
|
NHS-MA
|
Biochemical Assay Reagents
|
Others
|
|
Methacrylic acid N-hydroxysuccinimide ester (NHS-MA) is a polymer that serves as a monomer to prepare degradable amphiphilic block copolymer microparticles via RAFT polymerization for low pH-triggered drug delivery. Methacrylic acid N-hydroxysuccinimide ester is used for the synthesis of nanogels .
|
-
- HY-D3049
-
|
|
Fluorescent Dye
|
Others
|
|
5(6)-carbonylated rhodamine 110 NHS ester is a reactive ester fluorescent reagent based on 5(6)-carbonylated rhodamine 110. NHS ester is a highly reactive ester capable of covalently coupling with primary amine groups in molecules such as proteins, peptides, amino sugars, and nucleic acids to form stable amide bonds (Ex/Em = 502/527 nm).
|
-
- HY-135966
-
|
|
ADC Linkers
|
Cancer
|
|
Azido-PEG3-SS-NHS is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG3-SS-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-126525
-
|
|
ADC Linkers
|
Cancer
|
|
4-N3Pfp-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . 4-N3Pfp-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-157338
-
|
|
ADC Linkers
Kinesin
|
Cancer
|
|
NHS-Ala-Ala-Asn-active metabolite is a cleavable antibody-drug conjugate (ADC) linker for synthesis of kinesin spindle protein (KSP)inhibitor .
|
-
- HY-D2771
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 405 NHS Ester is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The NHS ester (or succinimidyl ester) is the most popular amine reactive group for labeling with the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. Proteins can be labeled with BP Fluor 405 NHS Ester at high molar ratios without significant self-quenching, leading to brighter conjugates and more sensitive detection. BP Fluor 405 conjugates can also be used for the detection of abundance targets.
|
-
- HY-141048
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(Azide-PEG3)-N'-(PEG4-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azide-PEG3)-N'-(PEG4-NHS ester)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133545
-
|
|
ADC Linkers
|
Cancer
|
|
Mal-Ph-CONH-PEG4- NHS ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-D3346
-
|
|
Fluorescent Dye
|
Others
|
|
Dusquench1 NHS ester is an amino-reactive fluorescent quencher (it does not emit light and has no emission wavelength, Ex = 480-580 nM), specially designed for labeling proteins, oligonucleotides and other biopolymers containing primary amines. It is a core reagent in the fields of qPCR probes, FRET detection and molecular beacons.
|
-
- HY-403874
-
-
- HY-133535
-
|
PA-JF646-NHS
|
Fluorescent Dye
|
Others
|
|
PA Janelia Fluor® 646, SE (PA-JF646-NHS) is a photo-activatable fluorescent dye. PA Janelia Fluor® 646, SE is a far-red light-excited, 405nm-activated NHS ester-based dye (λex/em = 650/664 nm). PA Janelia Fluor® 646, SE can achieve extremely low background and single-molecule-level ultra-high-resolution imaging through photo-controlled switching, making it a powerful tool for live cell super-resolution microscopy technology.
|
-
- HY-140770
-
|
|
PROTAC Linkers
|
Cancer
|
|
Azido-PEG3-aminoacetic acid-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-aminoacetic acid-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-126510
-
|
|
ADC Linkers
|
Cancer
|
|
MC-PEG2-C2- NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-D1692
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY 650/665 NHS ester is bright, far-red fluorescent dye that can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules . Ex / Em = 646 / 660 nm
|
-
- HY-D2757
-
|
|
Fluorescent Dye
|
Others
|
|
5(6)-Carboxyrhodamine 110 NHS Ester is the nonsulfonated analog of the BP Fluor 488 dye. The amine-reactive 5(6)-Carboxyrhodamine 110 NHS ester can be used to create bright and photostable green-fluorescent bioconjugates with excitation/emission maxima ~502/527 nm.
The conjugates of this dye often used for Fluorescence Correlation Spectroscopy (FCS).
|
-
- HY-D3050
-
|
|
Fluorescent Dye
|
Others
|
|
5(6)-carbonylated rhodamine 110 X NHS ester is a reactive ester fluorescent reagent based on 5(6)-carbonylated rhodamine 110 X. NHS ester is a highly reactive ester capable of covalently coupling with primary amine groups in molecules such as proteins, peptides, amino sugars, and nucleic acids to form stable amide bonds (Ex/Em = 496/522 nm).
|
-
- HY-141124
-
|
|
PROTAC Linkers
|
Cancer
|
|
NHS-PEG4-(m-PEG4)3-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141125
-
|
|
PROTAC Linkers
|
Cancer
|
|
NHS-PEG4-(m-PEG12)3-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D2096
-
|
|
Fluorescent Dye
|
Others
|
|
Alexa fluor 647 NHS ester can be used to label Alexa fluor 647 to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
-
- HY-169754
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 350 NHS ester is an amine reactive, water soluble, blue emitting dye used to specifically and efficiently modify primary amines at pH 7-9 to form stable covalent amide bonds .
|
-
- HY-133582
-
|
|
ADC Linkers
|
Cancer
|
|
Mal-amido-PEG3-C1- NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-D2736
-
|
|
Fluorescent Dye
|
Others
|
|
BP Light 800 NHS ester is an amine reactive hydrophilic fluorochrome . It can be conjugated to antibody with higher D/P ratio and widely used applications including western blotting, microscopy, flow cytometry, and cell based assays.
|
-
- HY-D1322
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine5.5 NHS ester tetrafluoroborate belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
|
-
- HY-140340
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-NH-pentanoic acid-NHS-SO3Na is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-112498
-
|
Cyanine3 NHS ester
|
Fluorescent Dye
|
Others
|
|
Cy3 NHS ester is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-157745
-
|
mPEG40000-SC; mPEG40000-Succinimidyl ester
|
Biochemical Assay Reagents
|
Others
|
|
m-PEG-NHS ester (mPEG-SC; mPEG-Succinimidyl ester) (MW 40000) is a polyethylene glycol derivative. m-PEG-NHS ester serves as a modifying agent that reacts with free amino groups on the surface of protein or polypeptide molecules to form stable amide bonds, thereby covalently linking PEG chains to biomacromolecules, improving their antigenicity and immunogenicity, and facilitating the preparation of injectable formulations .
|
-
- HY-172728
-
|
|
Fluorescent Dye
|
Others
|
|
Difluorocarboxyfluorescein NHS Ester, 6-isomer is an amine-reactive fluorinated analog of fluorescein that overcomes some of the key limitations of fluorescein, including greater photostability and a lower pKa (pKa ~ 4.7 versus 6.4 for fluorescein), making its fluorescence essentially pH insensitive in the physiological pH range. Although the mixed isomers of Difluorocarboxyfluorescein NHS Ester, is a preferred, routinely used fluorescent dye for labeling proteins, peptides and nucleotides, purification of peptide and nucleotides labeled with 5(6) isomers might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer usually give better resolution in HPLC purification that is often required in the conjugation processes.
|
-
- HY-W123004
-
|
N-Hydroxy-succinimidy-propionate octa(ethylene glycol)-disulfid
|
Biochemical Assay Reagents
|
Others
|
|
PEG NHS ester disulfide (N-Hydroxy-succinimidy-propionate octa(ethylene glycol)-disulfid) is a biochemical reagent.
|
-
- HY-D2328
-
|
Alexa Fluor 680 succinimidyl ester
|
Fluorescent Dye
|
Others
|
|
Alexa Fluor 680 NHS ester (Alexa Fluor 680 succinimidyl ester) is a near-infrared (NIR) fluorescent dye. NHS esters can be used to label to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules (Ex/Em = 679/702 nm) .
|
-
- HY-W615327
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Bis-sulfone NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact.
|
-
- HY-W071006
-
|
2,5-Dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate
|
ADC Linkers
|
Cancer
|
|
PPC-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-D2096A
-
|
|
Fluorescent Dye
|
Others
|
|
Alexa fluor 647 NHS ester TEA can be used to label Alexa fluor 647 to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
-
- HY-W190766
-
|
S-Acetyl-dPEG(R)8-NHS ester
|
Biochemical Assay Reagents
|
|
|
dPEG(R)8-SATA (S-Acetyl-dPEG(R)8-NHS ester) is a bioconjugation reagent with excellent biocompatibility and high selectivity. dPEG(R)8-SATA can be used to label and cross-link biomolecules and promote the interaction between biomolecules. dPEG(R)8-SATA plays an important role in bioimaging and compound delivery systems.
|
-
- HY-D1756
-
|
|
Fluorescent Dye
|
Others
|
|
ROX NHS ester, 6-isomer is a highly fluorescent, and photostable rhodamine dye for various applications. ROX labeled oligonucleotide probes are often used in qPCR, and qPCR instruments have ROX channel. This is reactive dye for the labeling of amino-groups in peptides, proteins, and amino-oligonucleotides. Pure single isomer.
|
-
- HY-176896
-
|
|
Others
|
Others
|
|
NHS-C2-(C-acid)-N-bis(C-Py-m-acid) (Compound 8) is a key intermediate for the synthesis of porphyrin-chelate conjugate .
|
-
- HY-W749072
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 568 NHS ester is an amine-reactive, orange fluorescent dye routinely used to label proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules (Ex/Em: 578 nm/602 nm) .
|
-
- HY-D2766
-
|
|
Fluorescent Dye
|
Others
|
|
BP Light 550 NHS ester is a vibrant orange-to-red fluorochrome with better performance than other rhodamine derivatives, including BP Fluor 555, TRITC, and Cy3 dye for fluorescent applications. The high water solubility of BP Light 550 means that a high dye-to-protein ratio can be attained without causing precipitation of the conjugates.
|
-
- HY-D2328A
-
|
Alexa Fluor 680 succinimidyl ester diTEA
|
Fluorescent Dye
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Others
|
|
Alexa Fluor 680 NHS ester (Alexa Fluor 680 succinimidyl ester) diTEA is a near-infrared (NIR) fluorescent dye. NHS esters can be used to label to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules (Ex/Em = 679/702 nm) .
|
-
- HY-112498A
-
|
Cyanine3 NHS ester bromide
|
Fluorescent Dye
|
Others
|
|
Cy3 NHS ester bromide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-130736
-
|
JF549, SE; JF549, NHS
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor® 549, SE (JF549, SE) is a cell-permeable fluorescent dye with an NHS ester (succinimidyl ester (SE)) reactive group. NHS esters react with primary amines and are commonly used to conjugate dyes to proteins, antibodies, amine-modified oligonucleotides, and other molecules. Janelia Fluor® 549, SE also acts as a ligand for self-labeling tags such as HaloTag and SNAP-tag, and can be used in live-cell imaging studies (Ex/Em = 549 nm/571 nm) .\n
|
-
- HY-126681
-
|
NHS-VC-PAB-MMAE
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
SC-VC-PAB-MMAE (NHS-VC-PAB-MMAE) is a agent-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker SC-VC-PAB .
|
-
- HY-D3239
-
|
AF405; Alexa Fluor 405 succinimidyl ester
|
Fluorescent Dye
OAT
|
Others
|
|
AF405 NHS Ester (AF405) is a Fluorescent probe substrate, as well as a substrate for OATP1B1, OATP1B3 and OATP2B1 .
|
-
- HY-140865
-
|
|
PROTAC Linkers
|
Cancer
|
|
2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . 2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D0049
-
|
6-TAMRA-NHS ester; 6-Carboxytetramethylrhodamine N-succinimidyl ester
|
DNA Stain
|
Others
|
|
6-TAMRA-SE (6-TAMRA-NHS ester) is a fluorescent dye carrying the amine reactive group. 6-TAMRA-SE is one of the traditional fluorophores used for automated DNA sequencing .
|
-
- HY-D1388
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 NHS ester is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-D1635
-
|
Biotin-XX-SSE
|
Fluorescent Dye
Exosomes
|
Infection
|
|
Sulfo-NHS-LC-LC-Biotin (Biotin-XX-SSE), a biotin reagent, is used to label the proteins exposed to the external leaflet of intact exosomes and contains a larger spacer arm between the biotin and amine reactive linker. The size of this linker helps to overcome steric hindrance and increases labeling efficiency at the crowded exosome surface .
|
-
- HY-D1223
-
|
|
Fluorescent Dye
|
Others
|
|
AF488 NHS ester diTEA is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
|
-
- HY-110212
-
|
BODIPY TR-X NHS ester
|
Fluorescent Dye
|
Others
|
|
BODIPY TR-X (BODIPY TR-X NHS Ester) is a potent fluorescent dye. BODIPY TR-X can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. BODIPY TR-X binds to protein or antibody and has bright, red fluorescent light. (λex=545 nm, λem=560 nm) .
|
-
- HY-131020
-
|
JF525, SE; JF525, NHS
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor 525, SE (JF525, SE) (the SE form of compound 12) is a yellow fluorescent dye (Ex = 525 nm; Em = 549 nm) . Janelia Fluor 525, SE contains an NHS ester, which can be used to label primary amines and is suitable for live cell imaging.
|
-
- HY-DY1069
-
|
|
Fluorescent Dye
|
Others
|
Cy3 NHS ester (solution) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-D2189
-
|
IR 700DX NHS ester
|
Fluorescent Dye
|
Others
|
|
IR 700DX (IR 700DX NHS ester) is a near-infrared (NIR) phthalocyanine dye with extremely high photostability and fluorescence intensity. IR 700DX binds to biomolecules. IR 700DX has excellent water solubility, large extinction coefficient, high fluorescence quantum yield, and does not aggregate in high ionic strength buffers. IR 700DX can be used as a highly flexible photosensitizer .
|
-
- HY-D1596
-
|
Cy3.5 NHS ester chloride; Cy 3.5 chloride
|
Fluorescent Dye
|
Others
|
|
Cyanine 3.5 (Cy3.5 NHS ester) chloride is an analog of Cy3.5 fluorophore. Cyanine 3.5 chloride is a reactive, red fluorescent dye. Cyanine 3.5 chloride is used for labeling of amino-groups in peptides, proteins, and oligonucleotides. (λex=591 nm, λem=604 nm) .
|
-
- HY-130989
-
|
NHS-Glutarate-Val-Cit-PAB-MMAE
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
SuO-Glu-Val-Cit-PAB-MMAE (NHS-Glutarate-Val-Cit-PAB-MMAE) consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-134124
-
|
|
Reactive Oxygen Species (ROS)
|
Metabolic Disease
|
|
Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .
|
-
- HY-131026
-
|
JF635, SE; JF635, NHS
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor 635, SE (JF635, SE) is a red fluorogenic fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. JF635, SE can be used for live cell imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-W012166
-
|
NHS-Bromoacetate
|
Biochemical Assay Reagents
|
Infection
|
|
N-Succinimidyl bromoacetate (NHS-Bromoacetate) is a heterobifunctional crosslinking reagent, mainly used to modify the ɛ-amino group of lysine side chains. By covalently linking its bromoacetyl moiety to the ɛ-amino group of lysine in peptidomimetics, N-Succinimidyl bromoacetate enables their conjugation with thiol-modified nanoparticles via thioether bonds. N-Succinimidyl bromoacetate also performs bromoacetylation modification on carrier proteins, which then forms stable thioether bonds with the thiol groups of cysteine in peptides, thus efficiently preparing soluble peptide-protein conjugates with high substitution ratios. N-Succinimidyl bromoacetate can be used to prepare activated Sepharose derivatives for affinity chromatography, protein affinity labeling reagents, and peptide-protein immunogen conjugates with non-immunogenic linkages. N-Succinimidyl bromoacetate is applicable to studies related to HIV-1 infection and glioblastoma multiforme .
|
-
- HY-D2738
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 532 NHS ester is an amine reactive, yellow-emitting dye routinely used to label proteins or antibodies through primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond.
BP Fluor 532 is a bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.
|
-
- HY-D0819A
-
|
Cy5 NHS ester triethylamine salt; Sulfo-Cyanine5 Succinimidyl ester triethylamine salt
|
Fluorescent Dye
|
Others
|
|
Cy5-SE (Cy5 NHS Ester) triethylamine salt is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. Cy5-SE triethylamine salt is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides Ex=649 nm; Em=670 nm) .
|
-
- HY-D1596A
-
|
Cy3.5 NHS ester bromide; Cy 3.5 bromide
|
Fluorescent Dye
|
Others
|
|
Cyanine 3.5 bromide (Cy3.5 NHS ester bromide) is an analog of the Cy3.5 fluorophore. Cyanine 3.5 bromide is a red reactive fluorescent dye. Cyanine 3.5 bromide is used to label amino groups in peptides, proteins, and oligonucleotides. (λex=591 nm, λem=604 nm) .
|
-
- HY-138658
-
|
JF526, SE; JF526, NHS
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor 526, SE (JF526,SE) is a fluorogenic yellow fluorescent dye that contains NHS ester group. JF526 is a versatile scaffold for fluorogenic ligands, including labels for genetically encoded self-labeling protein tags and stains for endogenous structures . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-D0819
-
CY5-SE
Maximum Cited Publications
37 Publications Verification
Cy5 NHS ester; Sulfo-Cyanine5 Succinimidyl ester
|
Fluorescent Dye
|
Others
|
|
Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling.
Excitation (nm):649, Emission (nm): 670.
|
-
- HY-D0925C
-
|
Cyanine5.5 NHS ester potassium
|
Fluorescent Dye
|
Others
|
|
Cy5.5-SE (Cyanine5.5 NHS ester) potassium is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-177682
-
|
|
Drug-Linker Conjugates for ADC
Topoisomerase
Microtubule/Tubulin
|
Cancer
|
|
N-(NHS-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE (HY-15162) and a DNA topoisomerase I inhibitor Exatecan (HY-13631), and an ADC linker composition. N-(NHS-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) can be used for synthesis of ADCs and for cancer research.
|
-
- HY-177688
-
|
|
Drug-Linker Conjugates for ADC
Topoisomerase
Microtubule/Tubulin
|
Cancer
|
|
N-(NHS-PEG4)-N-(PEG4-Val-Cit-PAB-MMAF)-N-(PEG4-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE (HY-15162) and a DNA topoisomerase I inhibitor Exatecan (HY-13631), and an ADC linker composition. N-(NHS-PEG4)-N-(PEG4-Val-Cit-PAB-MMAF)-N-(PEG4-Val-Cit-PAB-Exatecan) can be used for synthesis of ADCs and for cancer research.
|
-
- HY-D0925
-
|
Cyanine5.5 NHS ester
|
Fluorescent Dye
|
Others
|
|
Cy5.5-SE (Cyanine5.5 NHS ester) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance . Storage: protect from light.
|
-
- HY-D2745
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 594 NHS ester is the most popular tool for modifying proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules with BP Fluor 594 label. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond. BP Fluor 594 dye can be used for proteins labeling at high molar ratios without significant self-quenching, enabling brighter conjugates and more sensitive detection.
BP Fluor 594 is bright, water-soluble, and pH-insensitive from pH 4 to pH 10 red-fluorescent dye with absorption and emission maxima at 590 and 617 nm, respectively. It can be used with the 561 nm and 594 nm laser lines. BP Fluor 594 dye conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates often used for generation of stable signal in imaging and flow cytometry.
|
-
- HY-131025
-
|
JF585, SE; JF585, NHS
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor 585, SE (JF585, SE) is an orange fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. Janelia Fluor 585, SE can be used immediately for structured illumination (SIM) and stimulated emission depletion (STED) imaging and could be converted to photoactivatable derivative for single-molecule localization microscopy (SMLM) experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-138660
-
|
HM-JF526 NHS
|
Fluorescent Dye
|
Others
|
|
HM Janelia Fluor® 526, SE (HM-JF526 NHS) is a derivative of hydroxymethyl JF526 (HM-JF526). SMLM (single-molecule localization microscopy) imaging in standard phosphate-buffered saline (pH 7.4) revealed that the HM-JF526 label showed spontaneous blinking behavior throughout the imaging session and did not require short-wavelength activation light . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-D0925B
-
|
Cyanine5.5 NHS ester TEA
|
Fluorescent Dye
|
Others
|
|
Cy5.5-SE TEA (Cyanine5.5 NHS ester TEA) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance . Storage: protect from light.
|
-
- HY-W591384
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Boc-NH-PEG12-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
|
-
- HY-185464
-
|
|
Drug Derivative
|
Others
|
|
DBCO-Headpiece is a conjugate of DBCO-PEG4-NHS ester (HY-140272) and Headpiece (HY-185129).
|
-
- HY-P2424
-
-
- HY-D3498
-
-
- HY-D3350
-
-
- HY-D3481
-
-
- HY-136159
-
|
|
PROTAC Linkers
|
Cancer
|
|
3-Mercaptopropanyl-N-hydroxysuccinimide ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-D1106
-
|
|
Fluorescent Dye
|
Cancer
|
|
BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions . Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells .
|
-
- HY-D2060
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 740 is a near-infrared dye (Ex/Em: 740/764 nm). ATTO 740 can be conjugated with the Cetuximab antibody (HY-P9905) .
|
-
- HY-W800819
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Arachidic Acid N-Hydroxysuccinimide Ester is a lipid comprised of a saturated fatty acid with a 20-carbon chain with a terminal NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-W1049085H
-
|
mPEG-Succinimidyl Succinate ester (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-SS (MW 3400) (mPEG-Succinimidyl Succinate ester (MW 3400)) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG-SS (MW 3400) can be used for drug delivery .
|
-
- HY-47373
-
|
|
PROTAC Linkers
|
Cancer
|
|
Folate-PEG3-C2-acid is the acid fragment of Folate-PEG3-NHS ester (HY-133493), which belongs to the PEG-type PROTAC linker and is used to synthesize PROTAC molecules.
|
-
- HY-D3341
-
-
- HY-D3358
-
-
- HY-W422359A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Aminopurine-O-Ph-NHCO-C3-COOH hydrochloride is the acid form in the previous step of the final product 2-Aminopurine-O-Ph-NHCO-C3-NHS ester (HY-143336) .
|
-
- HY-W1049085C
-
|
mPEG20000-Succinimidyl Succinate ester
|
Biochemical Assay Reagents
|
Others
|
|
mPEG20000-SS (mPEG20000-Succinimidyl Succinate ester) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG20000-SS can be used for drug delivery .
|
-
- HY-W1049085B
-
|
mPEG10000-Succinimidyl Succinate ester
|
Biochemical Assay Reagents
|
Others
|
|
mPEG10000-SS (mPEG10000-Succinimidyl Succinate ester) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG10000-SS can be used for drug delivery .
|
-
- HY-W1049085E
-
|
mPEG2000-Succinimidyl Succinate ester
|
Biochemical Assay Reagents
|
Others
|
|
mPEG2000-SS (mPEG2000-Succinimidyl Succinate ester) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG2000-SS can be used for drug delivery .
|
-
- HY-W1049085D
-
|
mPEG40000-Succinimidyl Succinate ester
|
Biochemical Assay Reagents
|
Others
|
|
mPEG40000-SS (mPEG40000-Succinimidyl Succinate ester) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG40000-SS can be used for drug delivery .
|
-
- HY-W1049085
-
|
mPEG1000-Succinimidyl Succinate ester
|
Biochemical Assay Reagents
|
Others
|
|
mPEG1000-SS (mPEG1000-Succinimidyl Succinate ester) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG1000-SS can be used for drug delivery .
|
-
- HY-W1049085A
-
|
mPEG5000-Succinimidyl Succinate ester
|
Biochemical Assay Reagents
|
Others
|
|
mPEG5000-SS (mPEG5000-Succinimidyl Succinate ester) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG5000-SS can be used for drug delivery .
|
-
- HY-W016550
-
|
CHMI; NCMI; NSC 524431
|
Biochemical Assay Reagents
|
Others
|
|
N-Cyclohexylmaleimide is a compound containing a maleimide group, and this maleimide group can react with NHS ester.
|
-
- HY-D3494
-
-
- HY-W888697A
-
-
- HY-D3511
-
-
- HY-W800839
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TCO-PEG4-TFP Ester is an amine-reactive labeling reagent used to modify proteins, antibodies, and other amine-containing biopolymers. A 2,3,5,6-tetrafluorophenol (TFP) is a reactive ester that displays much better stability toward hydrolysis in aqueous media resulting in more efficiency and better reproducible labeling of biopolymers. TFP ester of carboxylic acids react with primary amines at the same rate as NHS ester forming covalent amide bond that is identical to one formed by the reaction between primary amines and NHS esters or sulfo-NHS esters.
|
-
- HY-W800753
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2,5-Dioxopyrrolidin-1-yl 6-bromohexanoate is an alkane linker with a terminal bromide and an NHS ester. The bromide is a very good leaving group for nucleophilic substitution reactions. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-W800754
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Bromo-octanoic acid 2,5-dioxo-pyrrolidin-1-yl ester is an alkane linker with a terminal bromide and an NHS ester. The bromide is a very good leaving group for nucleophilic substitution reactions. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-128925
-
AMAS
1 Publications Verification
|
ADC Linkers
|
Cancer
|
|
AMAS is a nonclaevable heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules.
|
-
- HY-160719
-
|
|
Peptide-Drug Conjugates (PDCs)
|
Inflammation/Immunology
|
|
NHS-activated 2-octynoic acid-BSA is an immunogen used to establish a mouse model of primary biliary cholangitis (PBC). When used in combination with Complete Freund's Adjuvant (HY-153808), NHS-activated 2-octynoic acid-BSA stimulates the body's immune system, which recognizes it as a foreign antigen and triggers an immune response against autologous biliary epithelial cells. This leads to the production of anti-PDC-E2 antibodies, causing bile duct damage and inflammation. NHS-activated 2-octynoic acid-BSA is promising for use in primary biliary cholangitis research .
|
-
- HY-103688
-
|
|
ADC Payloads
|
Cancer
|
|
AcBut-N-Ac-γ-Calicheamicin is an ADC cytotoxic payload that induces cell cycle arrest and apoptosis by causing DNA double-strand breaks. AcBut-N-Ac-γ-Calicheamicin is primarily used in the synthesis of antibody-drug conjugates (ADC) and holds promise for research in the field of cancer, including acute lymphoblastic leukemia (ALL) and other hematological malignancies .
|
-
- HY-W190926
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2,5 -Dioxo-1-pyrrolidinyl 11-azidoundecanoate is a linker containing an azide group and an NHS ester. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-23629
-
|
|
PROTAC Linkers
|
Cancer
|
|
16-Aminohexadecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. 16-Aminohexadecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
|
-
- HY-W401143
-
|
|
PROTAC Linkers
|
Cancer
|
|
15-Aminopentadecanoic Acid can be used as a PROTAC linker in the synthesis of PROTACs. 15-Aminopentadecanoic Acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
|
-
- HY-W739603
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-bifunctional dye potassium is a water soluble bifunctional dye possessing two terminal NHS ester functions. The NHS esters can react specifically and efficiently with primary amines such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond. The dye is useful for the cross-conjugation of amines, and for other advanced labeling applications.
|
-
- HY-W105727
-
|
|
PROTAC Linkers
|
Cancer
|
|
9-Aminononanoic acid can be used as a PROTAC linker and other conjugation in the synthesis of PROTACs. 9-Aminononanoic acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
|
-
- HY-W105744
-
|
|
PROTAC Linkers
|
Cancer
|
|
10-Aminodecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. 10-Aminodecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
|
-
- HY-W190929
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Diethyl 4-aminoheptanedioate contains a primary amine which can react with carboxylic acids, activated NHS esters and other carbonyls.
|
-
- HY-130112
-
|
NHS-C4-MTS
|
ADC Linkers
|
Cancer
|
|
N-Succinimidyloxycarbonylpropyl methanethiosulfonate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-D3475
-
-
- HY-D3474
-
-
- HY-W451460
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2,5-Dioxopyrrolidin-1-yl 2-(prop-2-yn-1-yloxy)acetate is a Click Chemistry reagent with a propargyl group and an NHS ester group. The propargyl group can react with biomolecules containing azide group via copper catalyzed Click Chemistry reaction. The NHS ester is an amine reactive group which can be used for derivatizing peptides, antibodies, amine coated surfaces, etc.
|
-
- HY-D2735
-
|
|
Fluorescent Dye
|
Others
|
|
QSY-9-succinimidyl ester is a nonfluorescent acceptor molecule with a terminal NHS ester group. QSY-9-succinimidyl ester has a wide and intense quenching range from 500-600 nm that makes it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with fluorescent dyes at 500 nm to 600 nm. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-D0975
-
|
|
ADC Linkers
|
Cancer
|
|
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
|
-
- HY-W190753
-
|
|
Biochemical Assay Reagents
|
Others
|
|
BocNH-PEG8-CH2CH2COONHS is a PEG linker containing an NHS ester and a Boc-protected amino group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The Boc group can be deprotected under mild acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-D1111
-
|
AFDye 568 NHS ester
|
Fluorescent Dye
|
Others
|
|
TFAX 568, SE is an orange fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 568, SE yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG) .
|
-
- HY-W1048567
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG1000-SCM is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .
|
-
- HY-W1048567B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG5000-SCM is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .
|
-
- HY-W1048567E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG40000-SCM is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .
|
-
- HY-W1048567D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG20000-SCM is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .
|
-
- HY-W1048567C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG10000-SCM is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .
|
-
- HY-W744780
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Docosahexaenoic Acid N-Succinimide is the succinimide analog of Docosahexaenoic Acid. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-W1048567A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG2000-SCM is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .
|
-
- HY-W1048567H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG3400-SCM is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .
|
-
- HY-129655
-
|
|
ADC Linkers
|
Cancer
|
|
Sulfo-SMPB sodium is a non-cleavable, heterobifunctional chemical cross-linking reagent which contains N-hydroxysuccinimide (NHS) ester and maleimide groups, allowing covalent conjugation of amine- and sulfhydryl-containing molecules .
|
-
- HY-W441005
-
|
|
Liposome
|
Cancer
|
|
Amino-Gly-Gly-DSPE (hydrochloride) is a specially modified phospholipid that has been used to synthesize liposomes. The terminal amine is reactive with an NHS ester compound or carboxylic acid molecule in the presence of activator, such as HATU or EDC.
|
-
- HY-W020546
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-amine TFA is a simple building block containing a DBCO moiety and an amine group. Amine is very reactive with NHS ester. DBCO is commonly used for copper-free Click Chemistry reactions.
|
-
- HY-132270
-
|
|
Fluorescent Dye
|
Others
|
|
FAM amine, 5-isomer is a fluorescein linker that undergoes enzymatic transamination. The addition of the amine group makes the compound more reactive with carboxylic acids, activated NHS ester and other carbonyl groups.
|
-
- HY-W998707
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA amine, 5-isomer hydrochloride is a rhodamine dye with excitation/emission maximum 553/575 nm. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
- HY-D0048
-
|
5-TAMRA-NHS ester; 5-Carboxytetramethylrhodamine succinimidyl ester
|
Fluorescent Dye
|
Others
|
|
5-TAMRA-SE is an amine-reactive fluorescent agent, and its conjugate produces bright, pH-insensitive orange-red fluorescence with good photostability (Ex/Em = 565/580 nm).
|
-
- HY-137251
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Sulfo-MBS sodium is a heterobifunctional crosslinker with a maleimide group and an N-hydroxysuccinimide (NHS) ester group, which can react with cysteine residues and lysine residues on proteins. Sulfo-MBS sodium be used for protein cross-linking studies .
|
-
- HY-W011412
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TSTU is used as a coupling reagent in peptide chemistry. TSTU can convert carboxylic acids into the corresponding N-hydroxysuccinimidyl (NHS) esters. TSTU can be applied to the attachment of labels to peptides, proteins, etc .
|
-
- HY-W090940
-
|
|
ADC Linkers
|
Cancer
|
|
H-Gly-Gly-Phe-OH is a tripeptide linker that may be used in the creation of antibody drug conjugates (ADCs). The N-terminal of the glycine tripeptide is free to perform a variety of reactions such as couplings with carboxylic acids or NHS esters.
|
-
- HY-131030
-
|
JF669, SE; JF669, NHS
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor 669, SE (JF669, SE), a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm) . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-130735
-
|
JF646, SE; JF646, NHS
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor 646, SE (JF646, SE) is a red fluorescent dye can be used in cellular imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-141385
-
|
3-(2-Bromoacetamido)propanoic acid NHS ester
|
PROTAC Linkers
ADC Linkers
|
Cancer
|
|
N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-Succinimidyl 3-(Bromoacetamido)propionate is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-172284
-
|
|
Fluorescent Dye
|
Others
|
|
6-TAMRA cadaverine has achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
|
-
- HY-140339
-
|
|
Biochemical Assay Reagents
|
Others
Cancer
|
|
ANB-NOS is a heterobifunctional crosslinker with lipophilic, uncharged properties suitable for intracellular conjugation. ANB-NOS contains an amine-reactive Nhydroxysuccinimide (NHS) ester and a photoactivatable nitrophenyl azide. ANB-NOS can be used for the research of fibrosarcoma and mammary adenocarcinoma .
|
-
- HY-157262
-
|
|
Hapten
|
Infection
|
Methyl isonicotinate-(CH2)2-COOH (hapten 2b) is a hapten that can be activated with NHS and DCC. Methyl isonicotinate-(CH2)2-COOH has more immunogenicity and hydrophobicity .
|
-
- HY-D2764
-
|
|
Fluorescent Dye
|
Others
|
|
Difluorocarboxyfluorescein cadaverine, 5-isomer is a carbonyl reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond.
|
-
- HY-W800651
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-SS-Amine hydrochloride is a cleavable biotinylation reagent. The amine group can react with carboxylic acids, activated NHS esters and other carbonyl groups. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP.
|
-
- HY-D2751
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 Cadaverine is a carboxyl/carbonyl reactive building block used widely to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond.
|
-
- HY-W190918
-
|
|
Biochemical Assay Reagents
|
Others
|
|
endo-BCN-PEG4-amine is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
- HY-W591352
-
|
|
Ligands for E3 Ligase
|
Cancer
|
|
Thalidomide-5-(C6-amine) is a PROTAC building block that contains an E3 ligase ligand substituted with a terminal amine group. The amine group can react with NHS ester group or carboxylic acid in the presence of EDC or HATU.
|
-
- HY-W190915
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4,7,10,13,16–Pentaoxanonadecane-1,19-diamine is a PEG based linker with two terminal amine groups. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
- HY-W441002
-
|
|
Drug Derivative
Drug Intermediate
|
Cancer
|
|
DSPE-succinic acid is a derivative of Succinic acid (HY-N0420) and an intermediate of DSPE-Doxorubicin. DSPE-succinic acid can be used to synthesize DSPE-Doxorubicin via EDC/NHS activation. DSPE-succinic acid is applicable to the research of triple-negative breast cancer .
|
-
- HY-160885
-
-
- HY-W591379
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Amino-PEG19-amine is a PEG linker containing two amine functional groups. The hydrophilic PEG spacer increases solubility in aqueous media. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
|
-
- HY-100216
-
SPDP
5 Publications Verification
SPDP Crosslinker; Py-ds-Prp-OSu
|
ADC Linkers
|
Cancer
|
|
SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) .
|
-
- HY-W190904
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Amino-1,3-bis(tert-butyldimethylsilanoxy)propane has a TBDMS, acid labile protecting group. TBDMS is used for the protection of alcohol groups. The primary amine is able to react with carboxylic acids, active NHS esters and other carbonyl compounds.
|
-
- HY-24592
-
|
|
PROTAC Linkers
|
Cancer
|
|
(S,E)-Cyclooct-2-enol is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
|
-
- HY-160885A
-
|
|
Drug-Linker Conjugates for ADC
Drug Intermediate
|
Others
|
|
NH2-Gly-PAB-Exatecan-D-glucuronic acid formic (Compound 8) is an intermediate that reacts with NHS-group-containing molecules to generate the ADC drug-linker conjugate Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179) .
|
-
- HY-155885
-
|
mPEG40000-NH2
|
Biochemical Assay Reagents
|
Others
|
|
mPEG40000-amine (mPEG40000-NH2) is a monofunctional polyPEG with a terminal amine. The coupling between NHS ester and amine produces a stable amide bond. The amine moieties is also reactive with carboxyl in the presence of activating agent .
|
-
- HY-W793100
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Endo-BCN-PEG2-Biotin is a PEG linker containing a BCN group and a terminal carboxylic acid. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
- HY-W154175
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Boc-DODA is a linker containing a Boc-protected amino group and a terminal amine. The Boc group can be deprotected under mild acidic conditions to form the free amine. The terminal amine is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
- HY-172270D
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
-
- HY-172270C
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
-
- HY-172270
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
-
- HY-172270A
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
-
- HY-W1048553C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG5000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG40000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG2000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG3400-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG20000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG1000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG10000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W590569
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Azido-PEG12-amine is a water soluble PEG compound. The azide group enables Click Chemistry. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The hydrophilic PEG arm increases solubility in aqueous media.
|
-
- HY-D0025
-
|
|
Fluorescent Dye
Drug Intermediate
|
Others
|
|
7-Amino-4-methylcoumarin-3-acetic acid (AMCA) serves as the parent structure of coumarin-based blue fluorescent dyes, and its activated form AMCA-NHS can directly conjugate with proteins (Ex/Em ≈ 350/440-460).
|
-
- HY-D1085
-
|
|
Fluorescent Dye
|
Others
|
|
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .
|
-
- HY-137023
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7 amine is a cyanine containing a free amine group, which can be conjugated with a variety of functionalities, including NHS esters, and epoxides. This NIR dye amine can be used to derivate various targets by the reaction with electrophilic groups, and also by enzymatical reactions involving transamination.
|
-
- HY-W012971
-
|
|
Biochemical Assay Reagents
|
Others
|
|
5-Amino-1-pentanol is a linker containing a hydroxyl group and amine group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
- HY-156301
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Methyltetrazine-amido-PEG8-amine Trifluoroacetate is a heterobifunctional linker containing a terminal methyltetrazine, which can react with TCO-containing compounds without the catalysis of Cu or elevated temperatures, and terminal amine, which reacts with NHS ester specifically and efficiently. The PEG spacer enhances water solubility.
|
-
- HY-W591353
-
|
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
|
Thalidomide-5-(PEG2-amine) is a PROTAC building block that contains an E3 ligase ligand substituted with a terminal amine group. The amine group can react with NHS ester group or carboxylic acid in the presence of EDC or HATU. The PEG spacer improves water solubility.
|
-
- HY-404548
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Sulfo-TAG TFP ester disodium is a tetrafluorophenyl (TFP) ester that can be coupled to proteins via primary amine groups. Sulfo-TAG TFP ester disodium is more hydrophobic than NHS esters and exhibits higher hydrolytic stability in aqueous solutions. Sulfo-TAG TFP ester disodium can be used for antibody labeling.
|
-
- HY-W479025
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Fmoc-DODA hydrochloride is a linker with an Fmoc-protected amine and a terminal amine group. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
- HY-D1372
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine3 amine hydrochloride, an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine hydrochloride has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λex=555 nm, λem=570 nm) .
|
-
- HY-W879032
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Endo-BCN-PEG4-Pomalidomide is a PEG derivative composed of BCN, PEG4 and Pomalidomide (HY-10984). The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
- HY-200288B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG3400-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG3400-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W590588
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Diethyl acetal-PEG4-amine is a PEG reagent containing an amino (NH2) group and a terminal diethyl acetal protecting group, which can be deprotected to form the free aldehyde. NH2 group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
|
-
- HY-W1052117A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMPE-PEG3400-COOH is a conjugate composed of DMPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMPE-PEG3400-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052873C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DPPE-PEG1000-COOH is a conjugate composed of DPPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DPPE-PEG1000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052117
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMPE-PEG2000-COOH is a conjugate composed of DMPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMPE-PEG2000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-183173D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSG-PEG10000-COOH is a conjugate composed of DSG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSG-PEG10000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-200288D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG10000-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG10000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052873B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DPPE-PEG5000-COOH is a conjugate composed of DPPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DPPE-PEG5000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052873A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DPPE-PEG3400-COOH is a conjugate composed of DPPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DPPE-PEG3400-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052117C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMPE-PEG1000-COOH is a conjugate composed of DMPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMPE-PEG1000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-183173C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSG-PEG5000-COOH is a conjugate composed of DSG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSG-PEG5000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-183173B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSG-PEG3400-COOH is a conjugate composed of DSG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSG-PEG3400-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W440706
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG2000-alcohol is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.
|
-
- HY-183173
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSG-PEG1000-COOH is a conjugate composed of DSG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSG-PEG1000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052873D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DPPE-PEG10000-COOH is a conjugate composed of DPPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DPPE-PEG10000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W591965
-
|
|
Biochemical Assay Reagents
|
Others
|
|
t-Boc-Aminooxy-pentane-amine is a linker containing an aminooxy group and a primary amine. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
- HY-200288
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG2000-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG2000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-183173A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSG-PEG2000-COOH is a conjugate composed of DSG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSG-PEG2000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-200288A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG1000-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG1000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052873
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DPPE-PEG2000-COOH is a conjugate composed of DPPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DPPE-PEG2000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052117D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMPE-PEG1000-COOH is a conjugate composed of DMPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMPE-PEG1000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-200288C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG5000-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG5000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052117B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMPE-PEG5000-COOH is a conjugate composed of DMPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMPE-PEG5000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-D1372A
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine3 amine (TFA), an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine (TFA) has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λex=555 nm, λem=570 nm) .
|
-
- HY-W879044
-
|
Endo-BCN-PEG15-NH2
|
Biochemical Assay Reagents
|
Others
|
|
Endo-BCN-PEG15-amine (Endo-BCN-PEG15-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
- HY-W879025
-
|
Endo-BCN-PEG8-NH2
|
Biochemical Assay Reagents
|
Others
|
|
Endo-BCN-PEG8-amine (Endo-BCN-PEG8-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
- HY-W879045
-
|
Endo-BCN-PEG5-NH2
|
Biochemical Assay Reagents
|
Others
|
|
Endo-BCN-PEG5-amine (Endo-BCN-PEG5-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
- HY-D3051
-
|
|
Fluorescent Dye
|
Others
|
|
5(6)-carbonylated rhodamine 110 amine is a primary amine fluorescent reagent based on 5(6)-carbonylated rhodamine 110. Primary amines can be covalently linked with various functional groups such as carboxylic acids, active esters (e.g., NHS esters), and isothiocyanates to achieve labeling (Ex/Em = 502/527 nm).
|
-
- HY-140895B
-
|
Biotin-PEG10000-NH2
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG10000-Amine (Biotin-PEG10000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
-
- HY-140895C
-
|
Biotin-PEG20000-NH2
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG20000-Amine (Biotin-PEG20000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
-
- HY-157414
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Azide-A-DSBSO crosslinker is a mass spectrometry (MS) cleavable, membrane permeable, homobifunctional, azide-labeled, acid-cleavable crosslinking peptide. Azide-A-DSBSO crosslinker crosslinks proteins via NHS ester reaction with lysine residues. Azide-A-DSBSO crosslinker can be used to study protein-protein interactions by cross-linking mass spectrometry (XL-MS) [1] .
|
-
- HY-W092344
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1,5-Bis-Boc-1,5,9-triazanonane is a linker containing two Boc-protected amino groups and a terminal amine. The Boc groups can be deprotected under mild acidic conditions to form the free amines. The terminal amine is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
- HY-140895D
-
|
Biotin-PEG40000-NH2
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG40000-Amine (Biotin-PEG40000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
-
- HY-W1113139
-
|
|
Biochemical Assay Reagents
|
Others
|
|
H2N-PEG4-C3-OH is a PEG linker with a terminal amino group that can react with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. Hydroxyl group can react with a variety of functional groups. PEG spacer improves the compound's aqueous solubility.
|
-
- HY-140895A
-
|
Biotin-PEG5000-NH2
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG5000-Amine (Biotin-PEG5000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
-
- HY-42213
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N1,N4-Bis-Boc-spermidine is a linker containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-42222
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N1,N5-Bis-Boc-spermidine is a linker containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-D3054
-
|
|
Fluorescent Dye
|
Others
|
|
5(6)-Rhodamine 6G amine is a primary amine fluorescent reagent based on Rhodamine 6G (HY-D0309). Primary amines can be covalently linked with various functional groups such as carboxylic acids, active esters (e.g., NHS esters), and isothiocyanates to achieve labeling (Ex/Em = 526/547 nm).
|
-
- HY-W190933
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Bis-PEG6-TFP ester is a PEG linker with two terminal TFP ester moieties. TFP esters are amine reactive and are also more stable than NHS esters against hydrolysis. The PEG chain increases the water solubility properties of compounds in aqueous media. The water solubility properties of PEG chains are enhanced as the PEG chain grows.
|
-
- HY-W1052523C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DPPE-PEG1000-NH2 is a conjugate composed of DPPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DPPE-PEG1000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
|
-
- HY-W800650
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Aminooxy-PEG1-amine is a chemical reagent containing an aminooxy group and a primary amine. The aminooxy group is reactive with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive withactivated NHS esters, or carboxylic acid in the presence of coupling reagent EDC. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term.
|
-
- HY-W1052523B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DPPE-PEG5000-NH2 is a conjugate composed of DPPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DPPE-PEG5000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
|
-
- HY-100216R
-
|
SPDP Crosslinker (Standard); Py-ds-Prp-OSu (Standard)
|
ADC Linkers
Reference Standards
|
Cancer
|
|
SPDP (Standard) is the analytical standard of SPDP (HY-100216). This product is intended for research and analytical applications. SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) .
|
-
- HY-WAA0302
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1,4-Bis-Boc-1,4,7-triazaheptane is a PEG derivative containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-P99239
-
|
HUJ-591; TLX591
|
PSMA
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
Rosopatamab (HuJ591) is a humanized antiPSMA IgG1 monoclonal antibody that can be used in cancer research, especially prostate cancer. Rosopatamab can be linked to the low-energy beta-emitting radioisotope lutetium-177 ( 177Lu) through the bifunctional chelator DOTA-NHS ester to obtain a radioimmunoconjugate that targets malignant prostate cells with high efficiency .
|
-
- HY-W800654
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG5-amine is a PEG linker containing a maleimide group and an amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-W1052523
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DPPE-PEG2000-NH2 is a conjugate composed of DPPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DPPE-PEG2000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052523D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DPPE-PEG10000-NH2 is a conjugate composed of DPPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DPPE-PEG10000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
|
-
- HY-W190922
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG4-amine is a PEG linker containing a maleimide group and an amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-W1052523A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DPPE-PEG3400-NH2 is a conjugate composed of DPPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DPPE-PEG3400-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
|
-
- HY-W190955
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-(t-butyl ester-PEG3)-N-bis(PEG3-amine) is a PEG reagent that can easily react with activated NHS esters or carboxylic acid in the presence of EDC or HATU. The t-butyl group can be deprotected under acidic conditions. The hydrophilic PEG spacers increase the compounds water solubility in aqueous media.
|
-
- HY-W101722
-
|
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl (9-aminononyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-W1048525B
-
|
8-Arm PEG40000-Amine
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG40000-NH2 (8-Arm PEG40000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W440807
-
|
|
Liposome
|
Others
|
|
Oleoyl-Gly-Lys-(m-PEG11)-NH2 is a PEG-lipid molecule featuring an oleoyl amide linked to a Gly-Lys dipeptide and a methoxy PEG11 chain on the C-terminus of the lysine. The lysine primary amine may be used in a wide variety of reactions with carboxylic acids, NHS esters, and carbonyl groups. The PEG linker provides aqueous solubility.
|
-
- HY-W1048526
-
|
8-Arm PEG5000-amine HCL salt
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG5000-NH2 (8-Arm PEG5000-amine) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048526C
-
|
8-Arm PEG10000-amine HCL salt
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG10000-NH2 (8-Arm PEG10000-amine) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048525C
-
|
8-Arm PEG10000-Amine
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG10000-NH2 (8-Arm PEG10000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048526B
-
|
8-Arm PEG40000-amine HCL salt
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG40000-NH2 (8-Arm PEG40000-amine) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048526A
-
|
8-Arm PEG20000-amine HCL salt
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG20000-NH2 (8-Arm PEG20000-amine) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048525
-
|
8-Arm PEG5000-Amine
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG5000-NH2 (8-Arm PEG5000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048525A
-
|
8-Arm PEG20000-Amine
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG20000-NH2 (8-Arm PEG20000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W440945
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG2000-amine is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The terminal amine can react with an NHS ester to form a stable amide linkage. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer. Reagent grade, for research use only.
|
-
- HY-W800649
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Aminooxy-PEG2-amine hydrochloride (compound L3) is an aqueous soluble crosslinker. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond, if a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term .
|
-
- HY-141147
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
7-O-(Amino-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Amino-PEG4)-paclitaxel can be used in the synthesis of Antibody-Drug Conjugates (ADCs) .
|
-
- HY-42972
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester ((HY-115524) and (HY-115545)), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-W1048843B
-
|
4-Arm PEG10000-amine
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG10000-NH2 (4-Arm PEG10000-amine) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048555B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG3400-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG3400-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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- HY-W1048843A
-
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4-Arm PEG5000-amine
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Biochemical Assay Reagents
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Others
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|
4-Arm PEG5000-NH2 (4-Arm PEG5000-amine) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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-
- HY-W800653
-
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Biochemical Assay Reagents
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Others
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|
N-(Azido-PEG3)-NH-PEG3-t-butyl ester is a click chemistry reagent with a terminal azide group and secondary amine NH group. NH group is reactive with NHS ester, The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The azide group can participate in Click Chemistry.
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- HY-W1048555D
-
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Biochemical Assay Reagents
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Others
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Mal-PEG10000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG10000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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-
- HY-W1048555H
-
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Biochemical Assay Reagents
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Others
|
|
Mal-PEG40000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG40000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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-
- HY-W1048519B
-
|
4-Arm PEG20000-amine HCL salt
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Biochemical Assay Reagents
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Others
|
|
4-Arm PEG20000-NH2 (4-Arm PEG20000-amine) hydrochloride is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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-
- HY-W451406B
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Biochemical Assay Reagents
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Others
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|
NH2-PEG1000-NH2 is a PEG (MW = 1000) derivative with NH2 groups at both ends. NH2-PEG-NH2 can be used as a crosslinking agent in bioconjugation, hydrogel preparation, and nanotechnology, and can form stable amide bonds with active carboxyl groups or NHS ester groups .
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-
- HY-W1048843C
-
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4-Arm PEG20000-amine
|
Biochemical Assay Reagents
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Others
|
|
4-Arm PEG20000-NH2 (4-Arm PEG20000-amine) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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-
- HY-W1052298
-
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DMPE-PEG2000-Amine
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Biochemical Assay Reagents
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Others
|
|
DMPE-PEG2000-NH2 (DMPE-PEG2000-Amine) is a conjugate composed of DMPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DMPE-PEG2000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
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-
- HY-W1048519C
-
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4-Arm PEG40000-amine HCL salt
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG40000-NH2 (4-Arm PEG40000-amine) hydrochloride is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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- HY-W1048572E
-
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PROTAC Linkers
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Others
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|
N3-PEG5000-NH2 is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG5000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
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- HY-W451406C
-
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Biochemical Assay Reagents
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Others
|
|
NH2-PEG2000-NH2 is a PEG (MW = 2000) derivative with NH2 groups at both ends. NH2-PEG-NH2 can be used as a crosslinking agent in bioconjugation, hydrogel preparation, and nanotechnology, and can form stable amide bonds with active carboxyl groups or NHS ester groups .
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- HY-W1048572A
-
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PROTAC Linkers
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Others
|
|
N3-PEG2000-NH2 is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG2000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
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-
- HY-W1048555C
-
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|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG5000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG5000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048519
-
|
4-Arm PEG5000-amine HCL salt
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG5000-NH2 (4-Arm PEG5000-amine) hydrochloride is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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-
- HY-W1052298B
-
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DMPE-PEG5000-Amine
|
Biochemical Assay Reagents
|
Others
|
|
DMPE-PEG5000-NH2 (DMPE-PEG5000-Amine) is a conjugate composed of DMPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DMPE-PEG5000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
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-
- HY-W1048843D
-
|
4-Arm PEG40000-amine
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG40000-NH2 (4-Arm PEG40000-amine) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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-
- HY-W1052298D
-
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DMPE-PEG10000-Amine
|
Biochemical Assay Reagents
|
|
|
DMPE-PEG2000-NH2 (DMPE-PEG2000-Amine) is a conjugate composed of DMPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DMPE-PEG2000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
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-
- HY-W1048519A
-
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4-Arm PEG10000-amine HCL salt
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Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG10000-NH2 (4-Arm PEG100000-amine) hydrochloride is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
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-
- HY-W451406D
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Biochemical Assay Reagents
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Others
|
|
NH2-PEG10000-NH2 is a PEG (MW = 10000) derivative with NH2 groups at both ends. NH2-PEG-NH2 can be used as a crosslinking agent in bioconjugation, hydrogel preparation, and nanotechnology, and can form stable amide bonds with active carboxyl groups or NHS ester groups .
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- HY-W1052298A
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DMPE-PEG3400-Amine
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Biochemical Assay Reagents
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Others
|
|
DMPE-PEG3400-NH2 (DMPE-PEG3400-Amine) is a conjugate composed of DMPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DMPE-PEG3400-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
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-
- HY-W1048555E
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Biochemical Assay Reagents
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Others
|
|
Mal-PEG20000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG20000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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-
- HY-W451406A
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Biochemical Assay Reagents
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Others
|
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NH2-PEG5000-NH2 is a PEG (MW = 5000) derivative with NH2 groups at both ends. NH2-PEG-NH2 can be used as a crosslinking agent in bioconjugation, hydrogel preparation, and nanotechnology, and can form stable amide bonds with active carboxyl groups or NHS ester groups .
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-
- HY-W1048555
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|
Biochemical Assay Reagents
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Others
|
|
Mal-PEG1000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG1000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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-
- HY-W1052298C
-
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DMPE-PEG1000-Amine
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Biochemical Assay Reagents
|
Others
|
|
DMPE-PEG1000-NH2 (DMPE-PEG1000-Amine) is a conjugate composed of DMPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DMPE-PEG1000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
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-
- HY-D2895E
-
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Rhodamine B-PEG5000-NH2
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Fluorescent Dye
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Others
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|
RB-PEG5000-NH2 (Rhodamine B-PEG5000-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .
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- HY-D2895A
-
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Rhodamine B-PEG600-NH2
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Fluorescent Dye
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Others
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RB-PEG600-NH2 (Rhodamine B-PEG600-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .
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-
- HY-141148
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Drug-Linker Conjugates for ADC
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Cancer
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7-O-(Cbz-N-amido-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Cbz-N-amido-PEG4)-paclitaxel can be used in the synthesis of Antibody-Drug Conjugates (ADCs) .
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-
- HY-W353622
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Biochemical Assay Reagents
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Others
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|
2,5-Dioxopyrrolidin-1-yl 4-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)butanoate represents a special biotinylation reagent with a terminal NHS ester that reacts specifically and efficiently with amine-bearing compounds.
|
-
![2,5-Dioxopyrrolidin-1-yl 4-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)butanoate](//file.medchemexpress.com/product_pic/hy-w353622.gif)
- HY-D2895C
-
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Rhodamine B-PEG2000-NH2
|
Fluorescent Dye
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Others
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|
RB-PEG2000-NH2 (Rhodamine B-PEG2000-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .
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-
- HY-D2895H
-
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Rhodamine B-PEG10000-NH2
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Fluorescent Dye
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Others
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|
RB-PEG10000-NH2 (Rhodamine B-PEG10000-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .
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-
- HY-D2895D
-
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Rhodamine B-PEG3400-NH2
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Fluorescent Dye
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Others
|
|
RB-PEG3400-NH2 (Rhodamine B-PEG3400-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .
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-
- HY-D2895B
-
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Rhodamine B-PEG1000-NH2
|
Fluorescent Dye
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Others
|
|
RB-PEG1000-NH2 (Rhodamine B-PEG1000-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .
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-
- HY-D2895
-
|
Rhodamine B-PEG400-NH2
|
Fluorescent Dye
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Others
|
|
RB-PEG400-NH2 (Rhodamine B-PEG400-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .
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-
- HY-W131541
-
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|
PROTAC Linkers
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Cancer
|
|
tert-Butyl (11-aminoundecyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. tert-Butyl (11-aminoundecyl)carbamate can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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-
- HY-183133B
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Biochemical Assay Reagents
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Others
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|
C16-PEG5000-COOH is a conjugate composed of a hexadecyl (C16 aliphatic chain), a PEG chain, and a carboxyl group (-COOH). C16-PEG5000-COOH combines the membrane compatibility of lipids with the carboxyl group, which can form amide bonds with primary amines via EDC/NHS activation, making it suitable for research in biomaterial construction and drug delivery.
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-
- HY-183168B
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Biochemical Assay Reagents
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Others
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|
C18-PEG5000-COOH is a conjugate composed of an octadecyl group (C18 aliphatic chain), a PEG chain, and a carboxyl group (-COOH). C18-PEG5000-COOH combines the membrane compatibility of lipids with the carboxyl group, which can form amide bonds with primary amines via EDC/NHS activation, making it suitable for research in biomaterial construction and drug delivery.
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-
- HY-183133A
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Biochemical Assay Reagents
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Others
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|
C16-PEG3400-COOH is a conjugate composed of a hexadecyl (C16 aliphatic chain), a PEG chain, and a carboxyl group (-COOH). C16-PEG3400-COOH combines the membrane compatibility of lipids with the carboxyl group, which can form amide bonds with primary amines via EDC/NHS activation, making it suitable for research in biomaterial construction and drug delivery.
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-
- HY-183168A
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Biochemical Assay Reagents
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Others
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|
C18-PEG3400-COOH is a conjugate composed of an octadecyl group (C18 aliphatic chain), a PEG chain, and a carboxyl group (-COOH). C18-PEG3400-COOH combines the membrane compatibility of lipids with the carboxyl group, which can form amide bonds with primary amines via EDC/NHS activation, making it suitable for research in biomaterial construction and drug delivery.
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-
- HY-183168
-
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Biochemical Assay Reagents
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Others
|
|
C18-PEG2000-COOH is a conjugate composed of an octadecyl group (C18 aliphatic chain), a PEG chain, and a carboxyl group (-COOH). C18-PEG2000-COOH combines the membrane compatibility of lipids with the carboxyl group, which can form amide bonds with primary amines via EDC/NHS activation, making it suitable for research in biomaterial construction and drug delivery.
|
-
- HY-183133
-
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Biochemical Assay Reagents
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Others
|
|
C16-PEG2000-COOH is a conjugate composed of a hexadecyl (C16 aliphatic chain), a PEG chain, and a carboxyl group (-COOH). C16-PEG2000-COOH combines the membrane compatibility of lipids with the carboxyl group, which can form amide bonds with primary amines via EDC/NHS activation, making it suitable for research in biomaterial construction and drug delivery.
|
-
- HY-109539
-
|
|
Antibody-Drug Conjugates (ADCs)
Apoptosis
|
Cancer
|
|
Gemtuzumab ozogamicin is an antibody-drug conjugate (ADC) consisting of a humanized immunoglobulin (IgG4) antibody directed against CD33 that is conjugated to the cytotoxic agent Calicheamicin (HY-19609). The antibody portion is Gemtuzumab (HY-P99971), and the drug-linker conjugate for ADC is N-Ac-γ-Calicheamicin-AcBut-NHS ester (HY-103688). Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia (AML) .
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-
- HY-W1048572C
-
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Azide-PEG1000-Amine
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Biochemical Assay Reagents
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Others
|
|
N3-PEG1000-NH2 (Azide-PEG1000-Amine) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG1000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
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-
- HY-W190905
-
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|
Biochemical Assay Reagents
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Others
|
|
N4, N9-di-Boc-spermine is a spermine linker containing two a Boc-protected amino groups and two amine groups. The Boc groups can be deprotected under mild acidic conditions to form the free amine. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Spermidine is a polyamine that modulates various cellular activities like cellular development and differentiation, stability of DNA, and apoptosis.
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-
- HY-W1048572H
-
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Azide-PEG10000-Amine
|
PROTAC Linkers
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Others
|
|
N3-PEG10000-NH2 (Azide-PEG10000-Amine) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG10000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
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-
- HY-DY1063
-
|
|
Fluorescent Dye
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Others
|
Cy5-SE (Cy5 NHS Ester) (solution) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling.
Excitation (nm) :649, Emission (nm) : 670.
Solvent and concentration: DMSO: 10 mM
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-
- HY-W1048572I
-
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Azide-PEG20000-Amine
|
PROTAC Linkers
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Others
|
|
N3-PEG20000-NH2 (Azide-PEG20000-Amine) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG20000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
|
-
- HY-W144703
-
|
9-Aminoheptadecane
|
Biochemical Assay Reagents
|
Others
|
|
Heptadecan-9-amine (9-Aminoheptadecane) is PEG linker containing a maleimide and TFP ester end group. Maleimide groups are reactive with thiols between pH 6.5 and 7.5. The TFP ester can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. The hydrophilic PEG chains increase the water solubility of a compound in aqueous media. Longer PEG chains have improved water solubility relative to shorter PEG chains.
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-
- HY-42972G
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester ((HY-115524) and (HY-115545)), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
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-
- HY-W1048572D
-
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Azide-PEG3400-Amine
|
PROTAC Linkers
|
Others
|
|
N3-PEG3400-NH2 (Azide-PEG3400-Amine) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG3400-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
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-
- HY-W348348
-
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Biochemical Assay Reagents
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Others
|
|
CbzNH-PEG3-CH2CH2NH2 is a PEG linker containing an amine group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
|
-
- HY-42773
-
|
1-Boc-1,8-diaminooctane
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl (8-aminooctyl)carbamate (1-Boc-1,8-diaminooctane) can be used as a PROTAC linker in the synthesis of PROTACs. tert-butyl (8-aminooctyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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-
- HY-W1048572J
-
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Azide-PEG40000-Amine
|
PROTAC Linkers
|
Others
|
|
N3-PEG40000-NH2 (Azide-PEG40000-Amine) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG40000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
|
-
- HY-130695
-
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|
ADC Linkers
|
Cancer
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|
N-(Amino-PEG5)-N-bis(PEG4-acid) is a PEG derivative containing an amino group with two terminal carboxylic acids. The amino group is reactive with carboxylic acids, activated NHS esters. The terminal carboxylic acids can react with primary amine groups in the presence of activators to form a stable amide bond. N-(Amino-PEG5)-N-bis(PEG4-acid) can be useful in the development of antibody drug conjugates (ADCs) .
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-
- HY-W1048547A
-
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HOOC-PEG2000-Amine
|
Biochemical Assay Reagents
|
Others
|
|
HOOC-PEG2000-NH2 (HOOC-PEG2000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547J
-
|
HOOC-PEG40000-Amine
|
PROTAC Linkers
|
Others
|
|
HOOC-PEG40000-NH2 (HOOC-PEG40000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547H
-
|
HOOC-PEG1000-Amine
|
Biochemical Assay Reagents
|
Others
|
|
HOOC-PEG1000-NH2 (HOOC-PEG1000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547E
-
|
HOOC-PEG20000-Amine
|
Biochemical Assay Reagents
|
Others
|
|
HOOC-PEG20000-NH2 (HOOC-PEG20000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547I
-
|
HOOC-PEG3400-Amine
|
Biochemical Assay Reagents
|
Others
|
|
HOOC-PEG3400-NH2 (HOOC-PEG3400-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547C
-
|
HOOC-PEG5000-Amine
|
Biochemical Assay Reagents
|
Others
|
|
HOOC-PEG5000-NH2 (HOOC-PEG5000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547D
-
|
HOOC-PEG10000-Amine
|
Biochemical Assay Reagents
|
Others
|
|
HOOC-PEG10000-NH2 (HOOC-PEG10000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W047688
-
|
1-Boc-1,10-diaminodecane
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl (10-aminodecyl) carbamate (1-Boc-1,10-diaminodecane) is a synthetic intermediate that serves as a PROTAC linker in PROTAC synthesis and other conjugation applications. tert-Butyl (10-aminodecyl) carbamate is an alkane chain with a terminal amine and a Boc-protected amino group. The amine group can react with carboxylic acids, active NHS esters, carbonyl groups (ketones, aldehydes), etc. The Boc group can be deprotected under mild acidic conditions to form a free amine .
|
-
- HY-W422109
-
|
|
Drug Derivative
|
Others
|
|
4-(6-Methyl-1,2,4,5-tetrazin-3-yl) benzoic acid is an asymmetric tetrazine derivative and a bioorthogonal reaction partner. 4-(6-Methyl-1,2,4,5-tetrazin-3-yl) benzoic acid can be conjugated with Bevacizumab (HY-P9906) via EDC/NHS activation while retaining the VEGF-binding affinity of the antibody, thus constructing a targeting agent for pretargeted immuno-PET/NIRF imaging .
|
-
- HY-145547
-
|
14:0 Lyso PE; 1-Myristoyl-2-hydroxy-sn-glycero-3-PE; 1-Tetradecanoyl-sn-glycero-3-phosphoethanolamine
|
Liposome
|
Metabolic Disease
|
|
1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells . Serum levels of 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine are elevated in patients with malignant breast cancer compared to healthy controls .
|
-
- HY-D2765
-
|
|
Biochemical Assay Reagents
|
Others
|
|
BP Fluor 405 Cadaverine is a carbonyl-reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. Another common application for BP Fluor 405 Cadaverine is cell fixing by treatment with formaldehyde or glutaraldehyde.
BP Fluor 405 is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode.
|
-
- HY-145547S
-
|
14:0 Lyso PE-d27; 1-Myristoyl-2-hydroxy-sn-glycero-3-PE-d27; 1-Tetradecanoyl-sn-glycero-3-phosphoethanolamine-d27
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine-d27 (14:0 Lyso PE-d27) is the deuterium labeled 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine. 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells .
|
-
- HY-W1048843AG
-
|
4-Arm PEG5000-amine
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG5000-NH2 (GMP) (4-Arm PEG5000-amine (GMP)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-W1048843AGL
-
|
4-Arm PEG5000-amine (GMP Like)
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG5000-NH2 (GMP Like) (4-Arm PEG5000-amine (GMP Like)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP like guidelines. GMP like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
- HY-D2772
-
|
|
Biochemical Assay Reagents
|
Others
|
|
5-TAMRA cadaverine can used to modify carboxylic acid group in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be reversibly coupled to aldehydes and ketones to form a Schiff base – which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3).
Although the mixed isomers of 5(6)-TAMRA cadaverine is a preferred, routinely used orange-fluorescent dye for staining proteins, it is rearly used for labeling peptides and nucleotides. Purification of 5(6)-TAMRA labeled peptide and nucleotides might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer TAMRA usually give better resolution in HPLC purification that is often required in the conjugation processes.
|
-
- HY-D2747
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 405 acid is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The carboxylic acid of BP Fluor 405 is a reagent of choice for the preparation of custom activated esters that often are not commercially available. Examples of such activated esters include sulfo-NHS, TFP (2,3,5,6-Tetrafluorophenol), and STP (4-Sulfo-2,3,5,6-Tetrafluorophenol, Sodium Salt). Another common application for the non-activated carboxylic acid is peptide modification during solid phase synthesis, which usually requires in-situ activation with peptide coupling regents, e.g. HATU. BP Fluor 405 acid is also often used for control experiments, and for calibration.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D0802
-
|
Biotin N-hydroxysuccinimide ester; NHS-Biotin
|
Fluorescent Dyes
|
|
Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.
|
-
- HY-111496
-
|
|
Fluorescent Dyes
|
|
Sulfo-NHS-SS-biotin sodium is a long-chain cleavable and cell-impermeant amine-reactive biotinylation reagent. Sulfo-NHS-SS-biotin sodium can be used for the labeling and purifying of cell-surface protein .
|
-
- HY-D1119
-
|
|
Fluorescent Dyes
|
|
AF647-NHS ester is an analog of Alexa Fluor 647 (AF647). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: Protect from light .
|
-
- HY-D1041
-
|
ICG-OSu
|
Fluorescent Dyes
|
|
ICG NHS ester (ICG-OSu) is a near-infrared fluorescent agent ICG derivative. ICG NHS ester is amine-reactive and has been widely used to design in vivo imaging probes .
|
-
- HY-110210
-
|
BODIPY FL,SE
|
Fluorescent Dyes
|
|
BODIPY FL NHS ester (BODIPY FL, SE) is a cell membranes-penatrable amine-reactive fluorescent probe. The maximum excitation/emission wavelength of the BODIPY-FL NHS ester are 502/511 nm, respectively. BODIPY-FL NHS ester has high stability and is insensitive to the polarity, pH and type of solvent, and can maintain stable fluorescence properties under different environmental conditions. BODIPY-FL NHS ester can be used for the synthesis of protease substrates, live cell imaging, protein labeling and immunoassay .
|
-
- HY-D1389
-
|
Sulfo-Cyanine5.5 NHS ester tripotassium
|
Fluorescent Dyes
|
Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging .
|
-
- HY-D1119C
-
|
|
Fluorescent Dyes
|
|
AF647-NHS ester is an analogue of Alexa Fluor 647 (AF647), which has excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.) .
|
-
- HY-123687
-
|
|
Fluorescent Dyes
|
|
DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-D0893
-
|
|
Fluorescent Dyes
|
|
NSP-SA-NHS is an acridinium ester that can be used for chemiluminescent immunoassay. A rapid and sensitive chemiluminescent immunoassay of Bisphenol A (BPA) with NSP-SA-NHS-labeled has been developed .
|
-
- HY-D1872
-
|
|
Fluorescent Dyes
|
|
800CW NHS ester is a near-infrared fluorescent dye active ester that can conjugate with amine-containing small molecules, antibodies, peptides, and other substances to form fluorescent conjugates. 800CW NHS ester exhibits high fluorescence quantum yield and low non-specific binding properties. 800CW NHS ester can be used in biomedical research such as microbial infection imaging, tumor imaging, and biochemical detection .
|
-
- HY-D2001
-
|
|
Fluorescent Dyes
|
|
ATTO 488 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 NHS ester is an NHS ester derivative of ATTO 488 that can be used to label proteins or antibodies.
|
-
- HY-172286
-
|
|
Fluorescent Dyes
|
|
Cy7 NHS ester is a fluorescent dye that can be used for fluorescent imaging study.
|
-
- HY-D1567
-
|
|
Fluorescent Dyes
|
|
Cy7.5 NHS ester is a fluorescent dye. Cy7.5 NHS ester can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester can be used for fluorescent imaging study (Ex/Em = 780/820 nm) .
|
-
- HY-D2801A
-
|
|
Fluorescent Dyes
|
|
FITC-PEG1000-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG1000-NHS can be used for fluorescent labeling and imaging .
|
-
- HY-D2365
-
|
|
Fluorescent Dyes
|
|
QSY 21 NHS is a dark quencher and an efficient energy transfer acceptor for far-red and near-infrared fluorescent probes. QSY 21 NHS operates at a wavelength range of 540-750 nm and is commonly used in FRET applications. QSY 21 NHS does not fluoresce under normal conditions. The NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides and other amine-containing molecules. QSY 21 NHS can be conjugated with dendritic poly-L-lysine to achieve intramolecular quenching of Cy5 fluorescence .
|
-
- HY-134620
-
|
|
Fluorescent Dyes
|
|
Cyanine 5 NHS ester tetrafluoroborate (Compound Cy5) is a cyanine dye that is used to in fluorescence detection of macromolecules. Cyanine 5 NHS ester tetrafluoroborate exhibits an excitation wavelength of 638 nm .
|
-
- HY-D1568
-
|
|
Fluorescent Dyes
|
|
Sulfo-Cy7.5 NHS ester is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester can be used for the research of NIR imaging applications .
|
-
- HY-D1800
-
|
VF 680 SE
|
Fluorescent Dyes
|
|
Vari Fluor 680 SE (VF 680 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=680 nm/700 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1801
-
|
VF 488 SE
|
Fluorescent Dyes
|
|
Vari Fluor 488 SE (VF 488 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=488 nm/513 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1691
-
|
|
Fluorescent Dyes
|
|
BODIPY-581/591 NHS ester is a bright, red fluorescent dye (excitation: 581 nm; emission: 591 nm). BODIPY-581/591 NHS ester can be used for the labeling of amine containing biomolecules .
|
-
- HY-D2746
-
|
|
Fluorescent Dyes
|
|
Cy5.5 bis-NHS ester is a reactive cyanine dye containing NHS ester which can be used to label amine groups in peptides, proteins, and oligonucleotides.
|
-
- HY-D2329
-
|
|
Fluorescent Dyes
|
|
Fluorescein-PEG4-NHS ester is a colorimetric probe formed by the reaction of adipic dihydrazide and fluorescein isothiocyanate .
|
-
- HY-42984
-
|
|
Fluorescent Dyes
|
|
BHQ-2 NHS is a dark quencher with no native emission due to the polyaromatic-azo backbone and a terminal NHS ester. UBHQ-2 NHS has a wide and intense quenching range from 560-670 nm, which makes it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with orange to far-red emitting dyes. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-D2166
-
|
|
Fluorescent Dyes
|
|
AF 594 NHS ester is a derivative of the red fluorescent dye AF 594 with high fluorescence quantum yield and high photostability (Ex=594 nm, Em=615 nm). AF 594 NHS ester can form an ester bond by reacting the NHS group with ammonia, with maximum excitation wavelength of 594 nm .
|
-
- HY-133536
-
|
PA-JF549-NHS
|
Fluorescent Dyes
|
|
PA Janelia Fluor 549, SE (PA-JF549-NHS) is a bright photoactivatable fluorophore of JF549,SE (JF549,NHS). JF549,SE (JF549,NHS) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm .
|
-
- HY-D2178
-
|
|
Fluorescent Dyes
|
|
AF 568 NHS ester is a derivative of the orange fluorescent dye AF 568. AF 568 NHS ester is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling. AF 568 exhibits maximum absorption wavelength of 579 nm and the maximum emission wavelength of 603 nm .
|
-
- HY-D1802
-
|
VF 425 SE
|
Fluorescent Dyes
|
|
Vari Fluor 425 SE (VF 425 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=430 nm/475 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1790
-
|
VF 640 SE
|
Fluorescent Dyes
|
|
Vari Fluor 640 SE (VF 640 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=648 nm/664 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1791
-
|
VF 750 SE
|
Fluorescent Dyes
|
|
Vari Fluor 750 SE (VF 750 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=747 nm/770 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D2801B
-
|
|
Fluorescent Dyes
|
|
FITC-PEG3400-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG3400-NHS can be used for fluorescent labeling and imaging .
|
-
- HY-D1848A
-
|
|
Fluorescent Dyes
|
|
Sulfo-Cy3-NHS ditriethylamine is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS ditriethylamine contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS ditriethylamine can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
|
-
- HY-D1959
-
|
|
Fluorescent Dyes
|
|
ATTO 565 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 NHS ester is an NHS ester derivative of ATTO 565 that can be used to label proteins or antibodies.
|
-
- HY-D1315
-
-
- HY-D2956
-
|
CLIP-GLA-NHS
|
Fluorescent Dyes
|
|
BC-GLA-NHS (CLIP-GLA-NHS) is a NHS-labeled CLIP tag, which is an amine-reactive crosslinker and can achieve site-specific protein labeling. The NHS ester of BC-GLA-NHS reacts with the primary amine of the target molecule (such as antibodies, quantum dots) in a pH 7.5-8.5 buffer solution to form a stable amide bond. After coupling, the BC molecule undergoes a nucleophilic substitution reaction with the active site (Cys) of the CLIP-tagged fusion protein, releasing benzylcytosine and forming an irreversible thioether bond, achieving covalent labeling. BC-GLA-NHS can be used for click chemistry labeling .
|
-
- HY-D2890
-
|
|
Fluorescent Dyes
|
|
5-TAMRA-NHS is a fluorescent dye that combines 5-TAMRA (HY-15942) with a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. 5-TAMRA-NHS can be used for fluorescent labeling and imaging (Ex/Em = 541/567 nm) .
|
-
- HY-D0167
-
|
|
Fluorescent Dyes
|
|
NHS-5(6)Carboxyrhodamine is a dye used for fluorescence labeling applications, where accurate dye/protein ratios can be obtained under native conditions .
|
-
- HY-D1993
-
|
|
Fluorescent Dyes
|
|
ATTO 647 NHS ester is a fluorescent label targeting free amino groups. ATTO 647 NHS ester can undergo a nucleophilic reaction with the free amino groups of EF-C peptide via its activated carboxylic acid group to form a stable covalent conjugate. ATTO 647 NHS ester-labeled nanofibers not only retain retroviral transduction-enhancing activity but also maintain stable fluorescent signals in both buffer and cell culture systems. ATTO 647 NHS ester is suitable for detection applications including fluorescence spectroscopy, microscopy and flow cytometry. ATTO 647 NHS ester has been used in studies related to HIV-1 infection .
|
-
- HY-153524
-
|
|
Fluorescent Dyes
|
|
ATTO 425 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 425 NHS ester is an NHS ester derivative of ATTO 425 that can be used to label proteins or antibodies.
|
-
- HY-W848699
-
|
|
Fluorescent Dyes
|
|
FAM NHS ester, 6-isomer is a hydrophilic fluorophore. The NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond.
|
-
- HY-D2291
-
|
|
Fluorescent Dyes
|
|
BODIPY TMR NHS ester is bright, orange fluorescent dye with Ex/Em of 544/570 nm. The NHS ester (or succinimidyl ester) of BODIPY TMR NHS ester is a popular tool for conjugating the dye to a protein or antibody. NHS esters can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
-
- HY-D1798
-
|
VF 350 SE
|
Fluorescent Dyes
|
|
Vari Fluor 350 SE (VF 350 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=350 nm/448 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1796
-
|
VF 594 SE
|
Fluorescent Dyes
|
|
Vari Fluor 594 SE (VF 594 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=585 nm/609 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D2801
-
|
|
Fluorescent Dyes
|
|
FITC-PEG400-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG400-NHS can be used for fluorescent labeling and imaging .
|
-
- HY-D1309
-
|
|
Fluorescent Dyes
|
|
Sulfo-cyanine3 NHS ester sodium is a water-soluble cyanine dye that contains NHS ester groups and is amino-reactive.
|
-
- HY-D1239
-
|
|
Fluorescent Dyes
|
|
BODIPY R6G NHS ester is a borondipyrromethene dye. BODIPY R6G NHS ester can be conjugated with proteins. BODIPY R6G NHS ester can be used for intracellular traces .
|
-
- HY-D1615
-
|
|
Fluorescent Dyes
|
|
BODIPY 530/550 NHS ester can be used for the stain of protein. BODIPY 530/550 NHS ester can be used for fluorescence OIM (oblique illumination microscopic) image .
|
-
- HY-D2046
-
|
|
Fluorescent Dyes
|
|
ATTO 532 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 NHS ester is an NHS ester derivative of ATTO 532 that can be used to label proteins or antibodies.
|
-
- HY-D1957
-
|
|
Fluorescent Dyes
|
|
ATTO 633 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 633 NHS ester is an NHS ester derivative of ATTO 633 that can be used to label proteins or antibodies.
|
-
- HY-D2019
-
|
|
Fluorescent Dyes
|
|
ATTO 550 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 NHS ester is an NHS ester derivative of ATTO 550 that can be used to label proteins or antibodies.
|
-
- HY-D2058
-
|
|
Fluorescent Dyes
|
|
ATTO 700 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 700 NHS ester is an NHS ester derivative of ATTO 700 that can be used to label proteins or antibodies.
|
- HY-D2073
-
|
|
Fluorescent Dyes
|
|
ATTO 680 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 680 NHS ester is an NHS ester derivative of ATTO 680 that can be used to label proteins or antibodies.
|
- HY-D1935
-
|
|
Fluorescent Dyes
|
|
ATTO 465 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 465 NHS ester is an NHS ester derivative of ATTO 465 that can be used to label proteins or antibodies.
|
- HY-D1119A
-
|
|
Fluorescent Dyes
|
|
AF647-NHS ester tripotassium is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
|
- HY-D2290
-
|
|
Fluorescent Dyes
|
|
Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .
|
- HY-135413
-
|
Sulfo-Cyanine5 NHS ester
|
Fluorescent Dyes
|
|
MeCY5-NHS estera is a reactive dye. MeCY5-NHS estera can be used for the labeling of proteins and nucleic acids.
|
- HY-D1799
-
|
VF 568 SE
|
Fluorescent Dyes
|
|
Vari Fluor 568 SE (VF 568 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=573 nm/595 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1794
-
|
VF 405 SE
|
Fluorescent Dyes
|
|
Vari Fluor 405 SE (VF 405 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=399 nm/421 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1797
-
|
VF 660 SE
|
Fluorescent Dyes
|
|
Vari Fluor 660 SE (VF 660 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=660 nm/679 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1792
-
|
VF 555 SE
|
Fluorescent Dyes
|
|
Vari Fluor 555 SE (VF 555 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=550 nm/561 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1795
-
|
VF 532 SE
|
Fluorescent Dyes
|
|
Vari Fluor 532 SE (VF 532 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=532 nm/545 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1803
-
|
VF 565 SE
|
Fluorescent Dyes
|
|
Vari Fluor 565 SE (VF 565 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=563 nm/594 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D2801C
-
|
|
Fluorescent Dyes
|
|
FITC-PEG5000-NHS is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG5000-NHS can be used for fluorescent labeling and imaging .
|
- HY-D2105
-
|
|
Fluorescent Dyes
|
|
TAMRA-PEG3-NHS is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NHS contains NHS groups that react with ammonia to form ester bonds.
|
- HY-D2106
-
|
|
Fluorescent Dyes
|
|
TAMRA-PEG4-NHS is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-NHS contains NHS groups that react with ammonia to form ester bonds.
|
- HY-D2107
-
|
|
Fluorescent Dyes
|
|
TAMRA-PEG8-NHS is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-NHS contains NHS groups that react with ammonia to form ester bonds.
|
- HY-D2477
-
|
|
Fluorescent Dyes
|
|
Sulfo-QSY21-NHS is a fluorescent dye, which contains a NHS group that can react with amine groups (-NH2) in proteins or other molecules to form stable amide bonds. Sulfo-QSY21-NHS can be used in the synthesis of activity-based probes (ABPs) .
|
- HY-D1848
-
|
|
Fluorescent Dyes
|
|
Sulfo-Cy3-NHS disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS disodium contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS disodium can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
|
- HY-D2767
-
|
|
Fluorescent Dyes
|
|
MB 660R NHS Ester is a fluroescent agent with a terminal NHS ester group.MB 660R NHS Ester is a far-red fluorescent dye that has a maximal absorption of 665 nm and emission at 690 nm. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
- HY-141085
-
|
|
Fluorescent Dyes
|
|
Carboxyfluorescein-PEG12-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-D2741
-
|
|
Fluorescent Dyes
|
|
MB 488 NHS ester is a fluroescent agent with a terminal NHS ester group. MB 488 NHS ester is a green fluorescent, very hydrophilic dye molecule that has a maximal absorption of 501 nm and emission at 524 nm. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
- HY-D1310
-
|
|
Fluorescent Dyes
|
|
Sulfo-cyanine3.5 NHS ester tripotassium is a water-soluble cyanine dye that contains NHS ester groups and is amino-reactive.
|
- HY-D1917
-
|
|
Fluorescent Dyes
|
|
ATTO 390 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 390 NHS ester is an NHS ester derivative of ATTO 390 that can be used to label proteins or antibodies.
|
- HY-D1929
-
|
|
Fluorescent Dyes
|
|
ATTO 594 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 594 NHS ester is an NHS ester derivative of ATTO 594 that can be used to label proteins or antibodies.
|
- HY-D2026
-
|
|
Fluorescent Dyes
|
|
ATTO 514 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 514 NHS ester is an NHS ester derivative of ATTO 514 that can be used to label proteins or antibodies.
|
- HY-D1999
-
|
|
Fluorescent Dyes
|
|
ATTO 665 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 665 NHS ester is an NHS ester derivative of ATTO 665 that can be used to label proteins or antibodies.
|
- HY-D1932
-
|
|
Fluorescent Dyes
|
|
ATTO 590 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 NHS ester is an NHS ester derivative of ATTO 590 that can be used to label proteins or antibodies.
|
- HY-D2238
-
- HY-D1119B
-
|
|
Fluorescent Dyes
|
|
AF647-NHS ester (trisodium) is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
|
- HY-135414A
-
|
|
Fluorescent Dyes
|
|
Cyanine5 NHS ester bromide is a active compound, can be used to label amino groups in peptides, proteins, and oligonucleotides. Cyanine5 NHS ester bromide is a cyanine dye, fluorescence-labeling neurotensin (8-13) via arginine residues .
|
- HY-D1568A
-
|
|
Fluorescent Dyes
|
|
Sulfo-Cy7.5 NHS ester tripotassium is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester tripotassium contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester tripotassium can be used for the research of NIR imaging applications .
|
- HY-149117
-
|
|
Fluorescent Dyes
|
|
AF430 NHS ester is an AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF430 NHS ester can be uesd for the labeling of amino-groups in peptides, proteins, and oligonucleotides. To achieve specific coupling of dye labels and biomolecules .
|
- HY-D2761
-
|
|
Fluorescent Dyes
|
|
DY-680-NHS ester is an amine reactive hydrophilic fluorochrome. It can be conjugated to an antibody with higher D/P ratio without causing fluorescence quenching and conjugate precipitation, and it is widely used in applications including western blotting, microscopy, flow cytometry, and cell-based assays. The spectrum has an excitation of 690nm and emission at 709nm.
|
- HY-D2884D
-
|
Rhodamine B-PEG3400-NHS
|
Fluorescent Dyes
|
|
RB-PEG3400-NHS (Rhodamine B-PEG3400-NHS) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. RB-PEG3400-NHS can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
- HY-D2884E
-
|
Rhodamine B-PEG5000-NHS
|
Fluorescent Dyes
|
|
RB-PEG5000-NHS (Rhodamine B-PEG5000-NHS) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. RB-PEG5000-NHS can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
- HY-D2884H
-
|
Rhodamine B-PEG10000-NHS
|
Fluorescent Dyes
|
|
RB-PEG10000-NHS (Rhodamine B-PEG10000-NHS) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. RB-PEG10000-NHS can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
- HY-D2884A
-
|
Rhodamine B-PEG600-NHS
|
Fluorescent Dyes
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|
RB-PEG600-NHS (Rhodamine B-PEG600-NHS) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. RB-PEG600-NHS can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
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- HY-D2884B
-
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Rhodamine B-PEG1000-NHS
|
Fluorescent Dyes
|
|
RB-PEG1000-NHS (Rhodamine B-PEG1000-NHS) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. RB-PEG1000-NHS can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
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- HY-D2884C
-
|
Rhodamine B-PEG2000-NHS
|
Fluorescent Dyes
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|
RB-PEG2000-NHS (Rhodamine B-PEG2000-NHS) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. RB-PEG2000-NHS can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
- HY-D2884
-
|
Rhodamine B-PEG400-NHS
|
Fluorescent Dyes
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|
RB-PEG400-NHS (Rhodamine B-PEG400-NHS) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. RB-PEG400-NHS can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
- HY-D3271
-
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|
Fluorescent Dyes
|
|
IR 750 NHS ester is a near-infrared fluorescent dye composed of IRDye 750 near-infrared fluorophore and NHS ester reactive group. IR 750 NHS ester can be applied to fluorescent labeling, imaging and detection.
|
- HY-D3228
-
|
|
Fluorescent Dyes
|
|
IR-820 NHS ester is a near-infrared Fluorescent dye. IR-820 NHS ester can be used for the preparation of IR820-E[c (RGDfK)]2 .
|
- HY-D3258
-
|
|
Fluorescent Dyes
|
|
AF 660 NHS ester is a fluorescent dye AF 660 derivative exhibits high fluorescence quantum yield and high photostability. AF 660 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 668/698 nm).
|
- HY-D3257
-
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|
Fluorescent Dyes
|
|
AF 546 NHS ester is a fluorescent dye AF 546 derivative exhibits high fluorescence quantum yield and high photostability. AF 546 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 554/570 nm).
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- HY-D3259
-
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|
Fluorescent Dyes
|
|
AF 680 NHS ester is a fluorescent dye AF 680 derivative exhibits high fluorescence quantum yield and high photostability. AF 680 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 684/707 nm).
|
- HY-D3256
-
|
|
Fluorescent Dyes
|
|
AF 532 NHS ester is a fluorescent dye AF 532 derivative exhibits high fluorescence quantum yield and high photostability. AF 532 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 530/555 nm).
|
- HY-D3272
-
|
|
Fluorescent Dyes
|
|
IR 680LT NHS ester is a fluorescent dye with an NHS ester moiety, which can be used to label antibodies, proteins, etc (Ex/Em = 675/694 nm) .
|
- HY-D3263
-
|
|
Fluorescent Dyes
|
|
IR 650 NHS ester is a far-red-fluorescent probe with NHS ester. NHS ester is the most popular amine-reactive group for labeling with the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. (Ex=651nm, Em=668 nm)
|
- HY-D3323
-
|
|
Fluorescent Dyes
|
|
AF 350 NHS ester is a fluorescent dye AF 350 derivative exhibits high fluorescence quantum yield and high photostability. AF 350 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 346/445 nm) .
|
- HY-D3325
-
|
|
Fluorescent Dyes
|
|
AF 700 NHS ester is a fluorescent dye AF 700 derivative exhibits high fluorescence quantum yield and high photostability. AF 700 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 702/723 nm).
|
- HY-D3326
-
|
|
Fluorescent Dyes
|
|
AF 750 NHS ester is a fluorescent dye AF 750 derivative exhibits high fluorescence quantum yield and high photostability. AF 750 NHS ester can form an ester bond with ammonia via the NHS group, and can be used to label proteins, amine-modified oligonucleotides, and other primary amines (R-NH2) containing amine molecules (Ex/Em = 753/782 nm).
|
- HY-D2001A
-
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|
Fluorescent Dyes
|
|
TTO 488 NHS ester TEA is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. TTO 488 NHS ester TEA is an NHS ester derivative of ATTO 488 that can be used to label proteins or antibodies.
|
- HY-135414
-
|
|
Fluorescent Dyes
|
|
Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .
|
- HY-D1352
-
|
|
Fluorescent Dyes
|
|
Sulfo-Cyanine7 NHS ester potassium is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
|
- HY-DY1072
-
|
ICG-OSu (solution)
|
Fluorescent Dyes
|
ICG NHS ester (ICG-OSu) (solution) is a near-infrared fluorescent agent ICG derivative. ICG NHS ester is amine-reactive and has been widely used to design in vivo imaging probes .
Solvent and concentration: DMSO: 10 mM
|
- HY-D2175
-
|
|
Fluorescent Dyes
|
|
AF 555 NHS ester is a bright, orange-red fluorescence probe. AF 555 NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules (Ex/Em = 552/566 nm) .
|
- HY-D1730A
-
|
|
Fluorescent Dyes
|
|
AF488 NHS ester TEA is an amine specific fluorescence probe (λem=525 nm=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
|
- HY-135415
-
|
|
Fluorescent Dyes
|
|
Cyanine5.5 NHS ester chloride is a reactive dye for the labeling of proteins, and antibodies and small molecular compounds .
|
- HY-135414B
-
|
|
Fluorescent Dyes
|
|
Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .
|
- HY-D2367
-
|
N-Hydroxysuccinimidyl rhodamine B ester
|
Fluorescent Dyes
|
|
Rhodamine B NHS ester (N-Hydroxysuccinimidyl rhodamine B ester) is an amine-reactive fluorescent probe (λex/λem: 564/589 nm, respectively). Rhodamine B NHS ester could react with Glycine (HY-Y0966) .
|
- HY-D2494
-
|
|
Fluorescent Dyes
|
|
Sulfo Cy7 bis-NHS ester is a derivative of Cy7 (HY-D0825) dye containing sulfonate ions. Sulfo Cy7 bis-NHS ester can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
- HY-D2486
-
|
|
Fluorescent Dyes
|
|
Sulfo Cy3 bis NHS ester is a derivative of Cy3 (HY-D0822) dye containing sulfonate ions. Sulfo Cy3 bis NHS ester can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
- HY-D2157
-
|
Coumarin 343-aminohexanoic acid-NHS ester
|
Fluorescent Dyes
|
|
Coumarin 343 X NHS ester is a homologue of Coumarin 343 (HY-W267364). Coumarin 343 is a hydrophilic fluorescent probe for use in microfluids.
|
- HY-D1352A
-
|
|
Fluorescent Dyes
|
|
Sulfo-Cyanine7 NHS ester (TEA) is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester (TEA) reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
|
- HY-D0823
-
CY3-SE
1 Publications Verification
Sulfo-Cy3 NHS ester; Sulfo Cyanine3 NHS ester
|
Fluorescent Dyes
|
|
Cy3-SE (Sulfo-Cy3 NHS ester; Sulfo Cyanine3 NHS ester) is a sulfonated cyanine dye-derived fluorescent labeling reagent with λex of about 515 nm and λem of about 568 nm. Cy3-SE can interact with the π-π stacking of biomolecules (e.g., nucleoside monophosphates, proteins), inhibiting the photoisomerization process and increasing the fluorescence quantum yield and lifetime .
|
- HY-D2062
-
|
|
Fluorescent Dyes
|
|
ATTO 740 NHS ester is a near-infrared fluorescent dye and a multimodal fluorescence/photoacoustic contrast agent with excellent near-infrared emission properties and extremely high photostability. The photoacoustic signal of ATTO 740 NHS ester shows no significant decrease after continuous irradiation with a 750 nm laser for 30 min, making it suitable for in vivo fluorescence imaging and photoacoustic contrast imaging. When conjugated with the cystine knot peptide R01, ATTO 740 NHS ester enables precise detection of integrin αvβ6-positive cells and tumors in nude mouse xenograft models .
|
- HY-135415A
-
|
|
Fluorescent Dyes
|
|
Cyanine5.5 NHS ester chloride TEA is a reactive dye for the labeling of proteins, and antibodies and small molecular compounds .
|
- HY-D2459
-
|
|
Fluorescent Dyes
|
|
Alexa Fluor 430 NHS ester is a compound that couples green fluorescent dye Alexa Fluor 430 to a protein or antibody. Alexa Fluor 430 is used for the generation of stable signals in imaging and flow cytometry. NHS ester can be used to label proteins, amine-modified oligonucleotides and other primary amines (R-NH2) containing amine molecules .
|
- HY-D3053
-
|
|
Fluorescent Dyes
|
|
5(6)-Rhodamine 6G NHS ester is a reactive ester fluorescent reagent based on Rhodamine 6G (HY-D0309). NHS ester is a highly reactive ester capable of covalently coupling with primary amine groups in molecules such as proteins, peptides, amino sugars, and nucleic acids to form stable amide bonds (Ex/Em = 526/547 nm).
|
- HY-D2444
-
|
|
Fluorescent Dyes
|
|
AF555 NHS is a red fluorescent dye with excellent fluorescence properties and light stability. The excitation wavelength is 556 nm and the emission wavelength is 571 nm, which can be used for protein labeling, antibody labeling, and cell imaging .
|
- HY-D0799A
-
|
|
Fluorescent Dyes
|
|
Sulfo-NHS-LC-Biotin is an amine-reactive ester derivative of biotin and cannot pass the intact blood-retinal barrier. It can be used to assess vascular permeability of the brain and retinal vasculature.
|
- HY-D1983
-
|
|
Fluorescent Dyes
|
|
ATTO 620 NHS-Ester is an activated ester derivative of ATTO 620, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 620/642 nm.
|
- HY-D1611
-
|
|
Fluorescent Dyes
|
|
BODIPY FL-C5 NHS Ester is a green-fluorescent dye that is reactive with primary amines on biomolecules such as peptides, proteins, modified nucleotides and biopolymers .
|
- HY-D1979
-
|
|
Fluorescent Dyes
|
|
ATTO 725 NHS-Ester is an activated ester derivative of ATTO 725, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 728/751 nm.
|
- HY-D1974
-
|
|
Fluorescent Dyes
|
|
ATTO 610 NHS-Ester is an activated ester derivative of ATTO 610, which can directly label proteins or antibodies. The maximum excitation/emission wavelength: 616/633 nm.
|
- HY-D2773
-
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|
Fluorescent Dyes
|
|
5-Carboxyrhodamine 110 NHS Ester is the nonsulfonated analog of the BP Fluor 488 dye. The amine-reactive 5(6)-Carboxyrhodamine 110 NHS Ester can be used to create bright and photostable green-fluorescent bioconjugates with excitation/emission maxima ~502/527 nm. For many applications, the dye is preferred over 5-(6)-carboxyfluorescein NHS ester or FITC because of its exceptional photostability and fluorescence insensitivity to pH (4-9).
Although the mixed isomers of Carboxyrhodamine 110 NHS Ester preferred, routinely used fluorescent dye for labeling proteins, peptides and nucleotides, purification of peptide and nucleotides labeled with 5(6) isomers might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer usually give better resolution in HPLC purification that is often required in the conjugation processes.
|
- HY-D1849
-
|
|
Fluorescent Dyes
|
|
Cy3B NHS ester is a fluorescent dye compound that is commonly used in biomarking and fluorescent labeling experiments, especially for labeling biomolecules containing amino functional groups (amine groups), such as proteins, antibodies or peptides.
|
- HY-D1496
-
|
|
Fluorescent Dyes
|
|
Fluorescent Red Mega 485 NHS-ester is an amine conjugating fluorescent biolabel that can be used to label proteins .
|
- HY-D2768
-
|
|
Fluorescent Dyes
|
|
BP Fluor 430 NHS Ester is a water-soluble, green-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The NHS ester (or succinimidyl ester) is the most popular amine reactive group for labeling the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. Proteins can be labeled with BP Fluor 430 NHS Ester at high molar ratios without significant self-quenching, leading to brighter conjugates and more sensitive detection.
|
- HY-D3049
-
|
|
Fluorescent Dyes
|
|
5(6)-carbonylated rhodamine 110 NHS ester is a reactive ester fluorescent reagent based on 5(6)-carbonylated rhodamine 110. NHS ester is a highly reactive ester capable of covalently coupling with primary amine groups in molecules such as proteins, peptides, amino sugars, and nucleic acids to form stable amide bonds (Ex/Em = 502/527 nm).
|
- HY-D2771
-
|
|
Fluorescent Dyes
|
|
BP Fluor 405 NHS Ester is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The NHS ester (or succinimidyl ester) is the most popular amine reactive group for labeling with the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. Proteins can be labeled with BP Fluor 405 NHS Ester at high molar ratios without significant self-quenching, leading to brighter conjugates and more sensitive detection. BP Fluor 405 conjugates can also be used for the detection of abundance targets.
|
- HY-D3346
-
|
|
Fluorescent Dyes
|
|
Dusquench1 NHS ester is an amino-reactive fluorescent quencher (it does not emit light and has no emission wavelength, Ex = 480-580 nM), specially designed for labeling proteins, oligonucleotides and other biopolymers containing primary amines. It is a core reagent in the fields of qPCR probes, FRET detection and molecular beacons.
|
- HY-133535
-
|
PA-JF646-NHS
|
Fluorescent Dyes
|
|
PA Janelia Fluor® 646, SE (PA-JF646-NHS) is a photo-activatable fluorescent dye. PA Janelia Fluor® 646, SE is a far-red light-excited, 405nm-activated NHS ester-based dye (λex/em = 650/664 nm). PA Janelia Fluor® 646, SE can achieve extremely low background and single-molecule-level ultra-high-resolution imaging through photo-controlled switching, making it a powerful tool for live cell super-resolution microscopy technology.
|
- HY-D1692
-
|
|
Fluorescent Dyes
|
|
BODIPY 650/665 NHS ester is bright, far-red fluorescent dye that can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules . Ex / Em = 646 / 660 nm
|
- HY-D2757
-
|
|
Fluorescent Dyes
|
|
5(6)-Carboxyrhodamine 110 NHS Ester is the nonsulfonated analog of the BP Fluor 488 dye. The amine-reactive 5(6)-Carboxyrhodamine 110 NHS ester can be used to create bright and photostable green-fluorescent bioconjugates with excitation/emission maxima ~502/527 nm.
The conjugates of this dye often used for Fluorescence Correlation Spectroscopy (FCS).
|
- HY-D3050
-
|
|
Fluorescent Dyes
|
|
5(6)-carbonylated rhodamine 110 X NHS ester is a reactive ester fluorescent reagent based on 5(6)-carbonylated rhodamine 110 X. NHS ester is a highly reactive ester capable of covalently coupling with primary amine groups in molecules such as proteins, peptides, amino sugars, and nucleic acids to form stable amide bonds (Ex/Em = 496/522 nm).
|
- HY-D2096
-
|
|
Fluorescent Dyes
|
|
Alexa fluor 647 NHS ester can be used to label Alexa fluor 647 to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
- HY-D2736
-
|
|
Fluorescent Dyes
|
|
BP Light 800 NHS ester is an amine reactive hydrophilic fluorochrome . It can be conjugated to antibody with higher D/P ratio and widely used applications including western blotting, microscopy, flow cytometry, and cell based assays.
|
- HY-D1322
-
|
|
Fluorescent Dyes
|
|
Cyanine5.5 NHS ester tetrafluoroborate belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
|
- HY-112498
-
|
Cyanine3 NHS ester
|
Fluorescent Dyes
|
|
Cy3 NHS ester is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
- HY-D2328
-
|
Alexa Fluor 680 succinimidyl ester
|
Fluorescent Dyes
|
|
Alexa Fluor 680 NHS ester (Alexa Fluor 680 succinimidyl ester) is a near-infrared (NIR) fluorescent dye. NHS esters can be used to label to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules (Ex/Em = 679/702 nm) .
|
- HY-D1756
-
|
|
Fluorescent Dyes
|
|
ROX NHS ester, 6-isomer is a highly fluorescent, and photostable rhodamine dye for various applications. ROX labeled oligonucleotide probes are often used in qPCR, and qPCR instruments have ROX channel. This is reactive dye for the labeling of amino-groups in peptides, proteins, and amino-oligonucleotides. Pure single isomer.
|
- HY-D2766
-
|
|
Fluorescent Dyes
|
|
BP Light 550 NHS ester is a vibrant orange-to-red fluorochrome with better performance than other rhodamine derivatives, including BP Fluor 555, TRITC, and Cy3 dye for fluorescent applications. The high water solubility of BP Light 550 means that a high dye-to-protein ratio can be attained without causing precipitation of the conjugates.
|
- HY-D2328A
-
|
Alexa Fluor 680 succinimidyl ester diTEA
|
Fluorescent Dyes
|
|
Alexa Fluor 680 NHS ester (Alexa Fluor 680 succinimidyl ester) diTEA is a near-infrared (NIR) fluorescent dye. NHS esters can be used to label to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules (Ex/Em = 679/702 nm) .
|
- HY-130736
-
|
JF549, SE; JF549, NHS
|
Fluorescent Dyes
|
|
Janelia Fluor® 549, SE (JF549, SE) is a cell-permeable fluorescent dye with an NHS ester (succinimidyl ester (SE)) reactive group. NHS esters react with primary amines and are commonly used to conjugate dyes to proteins, antibodies, amine-modified oligonucleotides, and other molecules. Janelia Fluor® 549, SE also acts as a ligand for self-labeling tags such as HaloTag and SNAP-tag, and can be used in live-cell imaging studies (Ex/Em = 549 nm/571 nm) .\n
|
- HY-D3239
-
|
AF405; Alexa Fluor 405 succinimidyl ester
|
Fluorescent Dyes
|
|
AF405 NHS Ester (AF405) is a Fluorescent probe substrate, as well as a substrate for OATP1B1, OATP1B3 and OATP2B1 .
|
- HY-D0049
-
|
6-TAMRA-NHS ester; 6-Carboxytetramethylrhodamine N-succinimidyl ester
|
Fluorescent Dyes
|
|
6-TAMRA-SE (6-TAMRA-NHS ester) is a fluorescent dye carrying the amine reactive group. 6-TAMRA-SE is one of the traditional fluorophores used for automated DNA sequencing .
|
- HY-D1388
-
|
|
Fluorescent Dyes
|
|
Cy3 NHS ester is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
- HY-D1223
-
|
|
Fluorescent Dyes
|
|
AF488 NHS ester diTEA is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
|
- HY-110212
-
|
BODIPY TR-X NHS ester
|
Fluorescent Dyes
|
|
BODIPY TR-X (BODIPY TR-X NHS Ester) is a potent fluorescent dye. BODIPY TR-X can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. BODIPY TR-X binds to protein or antibody and has bright, red fluorescent light. (λex=545 nm, λem=560 nm) .
|
- HY-131020
-
|
JF525, SE; JF525, NHS
|
Fluorescent Dyes
|
|
Janelia Fluor 525, SE (JF525, SE) (the SE form of compound 12) is a yellow fluorescent dye (Ex = 525 nm; Em = 549 nm) . Janelia Fluor 525, SE contains an NHS ester, which can be used to label primary amines and is suitable for live cell imaging.
|
- HY-DY1069
-
|
|
Fluorescent Dyes
|
Cy3 NHS ester (solution) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
Solvent and concentration: DMSO: 10 mM
|
- HY-D2189
-
|
IR 700DX NHS ester
|
Fluorescent Dyes
|
|
IR 700DX (IR 700DX NHS ester) is a near-infrared (NIR) phthalocyanine dye with extremely high photostability and fluorescence intensity. IR 700DX binds to biomolecules. IR 700DX has excellent water solubility, large extinction coefficient, high fluorescence quantum yield, and does not aggregate in high ionic strength buffers. IR 700DX can be used as a highly flexible photosensitizer .
|
- HY-D1596
-
|
Cy3.5 NHS ester chloride; Cy 3.5 chloride
|
Fluorescent Dyes
|
|
Cyanine 3.5 (Cy3.5 NHS ester) chloride is an analog of Cy3.5 fluorophore. Cyanine 3.5 chloride is a reactive, red fluorescent dye. Cyanine 3.5 chloride is used for labeling of amino-groups in peptides, proteins, and oligonucleotides. (λex=591 nm, λem=604 nm) .
|
- HY-131026
-
|
JF635, SE; JF635, NHS
|
Fluorescent Dyes
|
|
Janelia Fluor 635, SE (JF635, SE) is a red fluorogenic fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. JF635, SE can be used for live cell imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-D2738
-
|
|
Fluorescent Dyes
|
|
BP Fluor 532 NHS ester is an amine reactive, yellow-emitting dye routinely used to label proteins or antibodies through primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond.
BP Fluor 532 is a bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.
|
- HY-D0819A
-
|
Cy5 NHS ester triethylamine salt; Sulfo-Cyanine5 Succinimidyl ester triethylamine salt
|
Fluorescent Dyes
|
|
Cy5-SE (Cy5 NHS Ester) triethylamine salt is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. Cy5-SE triethylamine salt is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides Ex=649 nm; Em=670 nm) .
|
- HY-D1596A
-
|
Cy3.5 NHS ester bromide; Cy 3.5 bromide
|
Fluorescent Dyes
|
|
Cyanine 3.5 bromide (Cy3.5 NHS ester bromide) is an analog of the Cy3.5 fluorophore. Cyanine 3.5 bromide is a red reactive fluorescent dye. Cyanine 3.5 bromide is used to label amino groups in peptides, proteins, and oligonucleotides. (λex=591 nm, λem=604 nm) .
|
- HY-138658
-
|
JF526, SE; JF526, NHS
|
Fluorescent Dyes
|
|
Janelia Fluor 526, SE (JF526,SE) is a fluorogenic yellow fluorescent dye that contains NHS ester group. JF526 is a versatile scaffold for fluorogenic ligands, including labels for genetically encoded self-labeling protein tags and stains for endogenous structures . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-D0819
-
CY5-SE
Maximum Cited Publications
37 Publications Verification
Cy5 NHS ester; Sulfo-Cyanine5 Succinimidyl ester
|
Fluorescent Dyes
|
|
Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling.
Excitation (nm):649, Emission (nm): 670.
|
- HY-D0925
-
|
Cyanine5.5 NHS ester
|
Fluorescent Dyes
|
|
Cy5.5-SE (Cyanine5.5 NHS ester) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance . Storage: protect from light.
|
- HY-D2745
-
|
|
Fluorescent Dyes
|
|
BP Fluor 594 NHS ester is the most popular tool for modifying proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules with BP Fluor 594 label. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond. BP Fluor 594 dye can be used for proteins labeling at high molar ratios without significant self-quenching, enabling brighter conjugates and more sensitive detection.
BP Fluor 594 is bright, water-soluble, and pH-insensitive from pH 4 to pH 10 red-fluorescent dye with absorption and emission maxima at 590 and 617 nm, respectively. It can be used with the 561 nm and 594 nm laser lines. BP Fluor 594 dye conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates often used for generation of stable signal in imaging and flow cytometry.
|
- HY-131025
-
|
JF585, SE; JF585, NHS
|
Fluorescent Dyes
|
|
Janelia Fluor 585, SE (JF585, SE) is an orange fluorescent dye containing an NHS ester that can be conjugated with primary amine groups. Janelia Fluor 585, SE can be used immediately for structured illumination (SIM) and stimulated emission depletion (STED) imaging and could be converted to photoactivatable derivative for single-molecule localization microscopy (SMLM) experiments . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-D0925B
-
|
Cyanine5.5 NHS ester TEA
|
Fluorescent Dyes
|
|
Cy5.5-SE TEA (Cyanine5.5 NHS ester TEA) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance . Storage: protect from light.
|
- HY-D3238
-
- HY-D3498
-
- HY-D3350
-
- HY-D3481
-
- HY-D1106
-
|
|
Fluorescent Dyes
|
|
BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions . Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells .
|
- HY-D2060
-
|
|
Fluorescent Dyes
|
|
ATTO 740 is a near-infrared dye (Ex/Em: 740/764 nm). ATTO 740 can be conjugated with the Cetuximab antibody (HY-P9905) .
|
- HY-D3341
-
- HY-D3358
-
- HY-D3494
-
- HY-D3511
-
- HY-W739603
-
|
|
Fluorescent Dyes
|
|
Cy5-bifunctional dye potassium is a water soluble bifunctional dye possessing two terminal NHS ester functions. The NHS esters can react specifically and efficiently with primary amines such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond. The dye is useful for the cross-conjugation of amines, and for other advanced labeling applications.
|
- HY-D3475
-
- HY-D3474
-
- HY-D2735
-
|
|
Fluorescent Dyes
|
|
QSY-9-succinimidyl ester is a nonfluorescent acceptor molecule with a terminal NHS ester group. QSY-9-succinimidyl ester has a wide and intense quenching range from 500-600 nm that makes it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with fluorescent dyes at 500 nm to 600 nm. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
- HY-D1111
-
|
AFDye 568 NHS ester
|
Fluorescent Dyes
|
|
TFAX 568, SE is an orange fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 568, SE yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG) .
|
- HY-132270
-
|
|
Fluorescent Dyes
|
|
FAM amine, 5-isomer is a fluorescein linker that undergoes enzymatic transamination. The addition of the amine group makes the compound more reactive with carboxylic acids, activated NHS ester and other carbonyl groups.
|
- HY-W998707
-
|
|
Fluorescent Dyes
|
|
TAMRA amine, 5-isomer hydrochloride is a rhodamine dye with excitation/emission maximum 553/575 nm. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
- HY-D0048
-
|
5-TAMRA-NHS ester; 5-Carboxytetramethylrhodamine succinimidyl ester
|
Fluorescent Dyes
|
|
5-TAMRA-SE is an amine-reactive fluorescent agent, and its conjugate produces bright, pH-insensitive orange-red fluorescence with good photostability (Ex/Em = 565/580 nm).
|
- HY-131030
-
|
JF669, SE; JF669, NHS
|
Fluorescent Dyes
|
|
Janelia Fluor 669, SE (JF669, SE), a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm) . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-130735
-
|
JF646, SE; JF646, NHS
|
Fluorescent Dyes
|
|
Janelia Fluor 646, SE (JF646, SE) is a red fluorescent dye can be used in cellular imaging . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
- HY-172284
-
|
|
Fluorescent Dyes
|
|
6-TAMRA cadaverine has achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
|
- HY-D2764
-
|
|
Fluorescent Dyes
|
|
Difluorocarboxyfluorescein cadaverine, 5-isomer is a carbonyl reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond.
|
- HY-D2751
-
|
|
Fluorescent Dyes
|
|
BP Fluor 488 Cadaverine is a carboxyl/carbonyl reactive building block used widely to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond.
|
- HY-D0025
-
|
|
Fluorescent Dyes
|
|
7-Amino-4-methylcoumarin-3-acetic acid (AMCA) serves as the parent structure of coumarin-based blue fluorescent dyes, and its activated form AMCA-NHS can directly conjugate with proteins (Ex/Em ≈ 350/440-460).
|
- HY-D1085
-
|
|
Fluorescent Dyes
|
|
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .
|
- HY-137023
-
|
|
Fluorescent Dyes
|
|
Sulfo-Cy7 amine is a cyanine containing a free amine group, which can be conjugated with a variety of functionalities, including NHS esters, and epoxides. This NIR dye amine can be used to derivate various targets by the reaction with electrophilic groups, and also by enzymatical reactions involving transamination.
|
- HY-D1372
-
|
|
Fluorescent Dyes
|
|
Cyanine3 amine hydrochloride, an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine hydrochloride has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λex=555 nm, λem=570 nm) .
|
- HY-D1372A
-
|
|
Fluorescent Dyes
|
|
Cyanine3 amine (TFA), an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine (TFA) has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λex=555 nm, λem=570 nm) .
|
- HY-D3051
-
|
|
Fluorescent Dyes
|
|
5(6)-carbonylated rhodamine 110 amine is a primary amine fluorescent reagent based on 5(6)-carbonylated rhodamine 110. Primary amines can be covalently linked with various functional groups such as carboxylic acids, active esters (e.g., NHS esters), and isothiocyanates to achieve labeling (Ex/Em = 502/527 nm).
|
- HY-D3054
-
|
|
Fluorescent Dyes
|
|
5(6)-Rhodamine 6G amine is a primary amine fluorescent reagent based on Rhodamine 6G (HY-D0309). Primary amines can be covalently linked with various functional groups such as carboxylic acids, active esters (e.g., NHS esters), and isothiocyanates to achieve labeling (Ex/Em = 526/547 nm).
|
- HY-D2895E
-
|
Rhodamine B-PEG5000-NH2
|
Fluorescent Dyes
|
|
RB-PEG5000-NH2 (Rhodamine B-PEG5000-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .
|
- HY-D2895A
-
|
Rhodamine B-PEG600-NH2
|
Fluorescent Dyes
|
|
RB-PEG600-NH2 (Rhodamine B-PEG600-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .
|
- HY-D2895C
-
|
Rhodamine B-PEG2000-NH2
|
Fluorescent Dyes
|
|
RB-PEG2000-NH2 (Rhodamine B-PEG2000-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .
|
- HY-D2895H
-
|
Rhodamine B-PEG10000-NH2
|
Fluorescent Dyes
|
|
RB-PEG10000-NH2 (Rhodamine B-PEG10000-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .
|
- HY-D2895D
-
|
Rhodamine B-PEG3400-NH2
|
Fluorescent Dyes
|
|
RB-PEG3400-NH2 (Rhodamine B-PEG3400-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .
|
- HY-D2895B
-
|
Rhodamine B-PEG1000-NH2
|
Fluorescent Dyes
|
|
RB-PEG1000-NH2 (Rhodamine B-PEG1000-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .
|
- HY-D2895
-
|
Rhodamine B-PEG400-NH2
|
Fluorescent Dyes
|
|
RB-PEG400-NH2 (Rhodamine B-PEG400-NH2) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and an amino group. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds (Ex/Em=546/610 nm) .
|
- HY-DY1063
-
|
|
Fluorescent Dyes
|
Cy5-SE (Cy5 NHS Ester) (solution) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling.
Excitation (nm) :649, Emission (nm) : 670.
Solvent and concentration: DMSO: 10 mM
|
- HY-42972G
-
|
|
Fluorescent Dyes
|
|
DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester ((HY-115524) and (HY-115545)), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
- HY-D2765
-
|
|
Fluorescent Dyes
|
|
BP Fluor 405 Cadaverine is a carbonyl-reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. Another common application for BP Fluor 405 Cadaverine is cell fixing by treatment with formaldehyde or glutaraldehyde.
BP Fluor 405 is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode.
|
- HY-W1048843AG
-
|
4-Arm PEG5000-amine
|
Fluorescent Dyes
|
|
4-Arm PEG5000-NH2 (GMP) (4-Arm PEG5000-amine (GMP)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1048843AGL
-
|
4-Arm PEG5000-amine (GMP Like)
|
Fluorescent Dyes
|
|
4-Arm PEG5000-NH2 (GMP Like) (4-Arm PEG5000-amine (GMP Like)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP like guidelines. GMP like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-D2772
-
|
|
Fluorescent Dyes
|
|
5-TAMRA cadaverine can used to modify carboxylic acid group in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be reversibly coupled to aldehydes and ketones to form a Schiff base – which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3).
Although the mixed isomers of 5(6)-TAMRA cadaverine is a preferred, routinely used orange-fluorescent dye for staining proteins, it is rearly used for labeling peptides and nucleotides. Purification of 5(6)-TAMRA labeled peptide and nucleotides might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer TAMRA usually give better resolution in HPLC purification that is often required in the conjugation processes.
|
- HY-D2747
-
|
|
Fluorescent Dyes
|
|
BP Fluor 405 acid is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10.
The carboxylic acid of BP Fluor 405 is a reagent of choice for the preparation of custom activated esters that often are not commercially available. Examples of such activated esters include sulfo-NHS, TFP (2,3,5,6-Tetrafluorophenol), and STP (4-Sulfo-2,3,5,6-Tetrafluorophenol, Sodium Salt). Another common application for the non-activated carboxylic acid is peptide modification during solid phase synthesis, which usually requires in-situ activation with peptide coupling regents, e.g. HATU. BP Fluor 405 acid is also often used for control experiments, and for calibration.
|
| Cat. No. |
Product Name |
Type |
-
- HY-W441011
-
|
|
Biochemical Assay Reagents
|
|
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .
|
-
- HY-W441014
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG2000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG2000-NHS can be used in the study of drug delivery .
|
-
- HY-150241
-
|
|
Biochemical Assay Reagents
|
|
DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .
|
-
- HY-136304
-
|
|
Biochemical Assay Reagents
|
|
NHS-PEG1-SS-PEG1-NHS is a reversible linker for biomacromolecule link with active small molecule. NHS-PEG1-SS-PEG1-NHS can be used in proteins liposomes or nanoparticles .
|
-
- HY-174892
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG5-NHS ester is a heterobifunctional crosslinker as well as a polyethylene glycol-containing bioconjugation reagent. Biotin-PEG5-NHS ester is widely used in scientific research fields such as the construction of highly sensitive biosensors, the development of targeted drug delivery systems (e.g., liposome modification), immunofluorescence imaging, and protein affinity purification, and serves as an important tool for achieving precise labeling and functionalization of biomolecules .
|
-
- HY-W441013
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG1000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG1000-NHS can be used in the study of drug delivery .
|
-
- HY-174893
-
|
|
Biochemical Assay Reagents
|
|
Azido-PEG20-NHS ester is a PEG derivative that can be used for drug delivery and other research. Azido-PEG20-NHS ester is a click chemistry reagent. Azido-PEG20-NHS contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group. Azido-PEG20-NHS can also undergo ring strain driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
|
-
- HY-W437745
-
|
|
Biochemical Assay Reagents
|
|
Desthiobiotin-NHS ester is a biotinylated biochemical assay reagent that reacts with amine groups (such as lysine residues) of proteins or other biomolecules to form stable amide bonds. Desthiobiotin-NHS ester can be used as probes for metalloproteins .
|
-
- HY-W190908A
-
|
|
Biochemical Assay Reagents
|
|
Desthiobiotin-PEG4-NHS ester is a PEG derivative composed of desthiobiotin, 4 PEG units, and NHS ester. NHS ester can be conjugated to amino acids or other molecules containing amino groups.
|
-
- HY-W440702
-
|
|
Biochemical Assay Reagents
|
|
Cholesterol-PEG2000-NHS is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG2000-NHS can be used in drug delivery research .
|
-
- HY-W777012
-
|
|
Biochemical Assay Reagents
|
|
Acridinium C2 NHS ester is a chemiluminescent label that is active for the development of protein and nucleic acid probes. Acridinium C2 NHS ester can be used in bioanalysis and diagnostics to provide highly sensitive detection solutions. Acridinium C2 NHS ester is widely used in medical research, especially in the monitoring and analysis of biomolecules.
|
-
- HY-172355A
-
|
|
Biochemical Assay Reagents
|
|
Azide-PEG-NHS (Mn 5000) is an azide PEG NHS ester that can be used for click chemistry reactions and can also be used to synthesize PEG hydrogels .
|
-
- HY-W879004
-
|
|
Biochemical Assay Reagents
|
|
m-PEG16-NHS ester is a PEG derivative composed of an NHS ester that can be conjugated to amino acids or other molecules containing amino groups .
|
-
- HY-W440697
-
|
|
Biochemical Assay Reagents
|
|
Cholesterol-PEG1000-NHS is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG1000-NHS can be used in drug delivery research .
|
-
- HY-158072
-
|
|
Biochemical Assay Reagents
|
|
DOTAM-NHS-ester is a bifunctional chelator and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTAM-NHS-ester combines the efficient metal chelating ability of DOTAM macrocyclic ligands with the bioconjugation function of NHS ester active groups, and can be widely used in the biomedical field for metal labeling, molecular imaging and drug delivery development .
|
-
- HY-174935
-
|
|
Biochemical Assay Reagents
|
|
DBCO-PEG1000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .
|
-
- HY-W190908C
-
|
|
Biochemical Assay Reagents
|
|
Desthiobiotin-PEG12-NHS ester is a PEG derivative composed of desthiobiotin, 12 PEG units, and NHS ester. NHS ester can be conjugated to amino acids or other molecules containing amino groups.
|
-
- HY-W190908B
-
|
|
Biochemical Assay Reagents
|
|
Desthiobiotin-PEG6-NHS ester is a PEG derivative composed of desthiobiotin, 6 PEG units, and NHS ester. NHS ester can be conjugated to amino acids or other molecules containing amino groups.
|
-
- HY-174935A
-
|
|
Biochemical Assay Reagents
|
|
DBCO-PEG2000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .
|
-
- HY-W588706
-
|
|
Biochemical Assay Reagents
|
|
Tetrazine-PEG5-SS-NHS ester is a heterobifunctional crosslinking agent, a PEG derivative composed of NHS ester. NHS ester can bind to amino acids or other amino-containing molecules. Tetrazine-PEG5-SS-NHS ester is used in bioconjugation, bioorthogonal chemistry, and delivery.
|
-
- HY-172354
-
|
|
Biochemical Assay Reagents
|
|
Acrylate-PEG2000-NHS is a photosensitive PEG compound that can be cross-linked when exposed to ultraviolet light and is used to synthesize PEG hydrogels .
|
-
- HY-W441012
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG600-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG600-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG600-NHS can be used in the study of drug delivery .
|
-
- HY-174888
-
|
|
Biochemical Assay Reagents
|
|
DBCO-PEG16-NHS ester is a PEG derivative consisting of DBCO, PEG units, and NHS ester. NHS ester can bind to amino acids or other molecules containing amino groups. DBCO-PEG16-NHS ester contains a DBCO group and can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
|
-
- HY-172354A
-
|
|
Biochemical Assay Reagents
|
|
Acrylate-PEG3500-NHS is a photosensitive PEG compound that can be cross-linked when exposed to ultraviolet light and is used to synthesize PEG hydrogels .
|
-
- HY-174959D
-
|
|
Biochemical Assay Reagents
|
|
6-Arm-PEG3400-NHS is a six-arm PEG derivative that can be used for peptide modification and drug delivery .
|
-
- HY-W440704
-
|
|
Biochemical Assay Reagents
|
|
Cholesterol-PEG5000-NHS is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG5000-NHS can be used in drug delivery research .
|
-
- HY-174935C
-
|
|
Biochemical Assay Reagents
|
|
DBCO-PEG5000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .
|
-
- HY-W1120356
-
-
- HY-W1048512C
-
|
|
Biochemical Assay Reagents
|
|
2-Arm PEG5000-NHS is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
-
- HY-174959B
-
|
|
Biochemical Assay Reagents
|
|
6-Arm-PEG1000-NHS is a six-arm PEG derivative that can be used for peptide modification and drug delivery .
|
-
- HY-174959
-
|
|
Biochemical Assay Reagents
|
|
6-Arm-PEG400-NHS is a six-arm PEG derivative that can be used for peptide modification and drug delivery .
|
-
- HY-W1048512A
-
|
|
Biochemical Assay Reagents
|
|
2-Arm PEG20000-NHS is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
-
- HY-174948
-
|
NHS-PEG1000-Aldehyde
|
Biochemical Assay Reagents
|
|
NHS-PEG1000-CHO (NHS-PEG1000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
- HY-174948C
-
|
NHS-PEG5000-Aldehyde
|
Biochemical Assay Reagents
|
|
NHS-PEG5000-CHO (NHS-PEG5000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
- HY-W588715D
-
|
|
Biochemical Assay Reagents
|
|
Acid-PEG6-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
|
-
- HY-W588715A
-
|
|
Biochemical Assay Reagents
|
|
Acid-PEG2-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
|
-
- HY-W588715
-
|
|
Biochemical Assay Reagents
|
|
Acid-PEG8-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
|
-
- HY-W588715B
-
|
|
Biochemical Assay Reagents
|
|
Acid-PEG12-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
|
-
- HY-174892B
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG20-NHS ester is a PEG derivative composed of Biotin, 20 PEG units, and NHS ester. Biotin can form a stable non-covalent bond with streptavidin. NHS ester can bind to amino acids or other molecules containing amino groups .
|
-
- HY-W440703
-
|
|
Biochemical Assay Reagents
|
|
Cholesterol-PEG3400-NHS is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG3400-NHS can be used in drug delivery research .
|
-
- HY-174935B
-
|
|
Biochemical Assay Reagents
|
|
DBCO-PEG3400-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .
|
-
- HY-174935D
-
|
|
Biochemical Assay Reagents
|
|
DBCO-PEG10000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .
|
-
- HY-W1120356C
-
-
- HY-W1120356B
-
-
- HY-174264B
-
-
- HY-174264C
-
-
- HY-172355
-
|
|
Biochemical Assay Reagents
|
|
Azide-PEG-NHS (Mn 3500) is an azide PEG NHS ester that can be used for click chemistry reactions and can also be used to synthesize PEG hydrogels .
|
-
- HY-172354B
-
|
|
Biochemical Assay Reagents
|
|
Acrylate-PEG5000-NHS is a photosensitive PEG compound that can be cross-linked when exposed to ultraviolet light and is used to synthesize PEG hydrogels .
|
-
- HY-174959H
-
|
|
Biochemical Assay Reagents
|
|
6-Arm-PEG10000-NHS is a six-arm PEG derivative that can be used for peptide modification and drug delivery .
|
-
- HY-174959C
-
|
|
Biochemical Assay Reagents
|
|
6-Arm-PEG2000-NHS is a six-arm PEG derivative that can be used for peptide modification and drug delivery .
|
- HY-W1048603E
-
|
|
Biochemical Assay Reagents
|
|
4-arm PEG1000-NHS is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
- HY-W1048603J
-
|
|
Biochemical Assay Reagents
|
|
4-arm PEG5000-NHS is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
- HY-W190745
-
|
|
Biochemical Assay Reagents
|
|
DNP-PEG8-NHS ester is a PEG derivative that contains DNP (2,4-dinitroaniline), eight PEG units, and NHS ester. NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). DNP-PEG8-NHS ester can be used for drug delivery.
|
- HY-W190745A
-
|
|
Biochemical Assay Reagents
|
|
DNP-PEG2-NHS ester is a PEG derivative that contains DNP (2,4-dinitroaniline), two PEG units, and NHS ester. NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). DNP-PEG2-NHS ester can be used for drug delivery.
|
- HY-W190745B
-
|
|
Biochemical Assay Reagents
|
|
DNP-PEG3-NHS ester is a PEG derivative that contains DNP (2,4-dinitroaniline), three PEG units, and NHS ester. NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). DNP-PEG3-NHS ester can be used for drug delivery.
|
- HY-174948B
-
|
NHS-PEG3400-Aldehyde
|
Biochemical Assay Reagents
|
|
NHS-PEG3400-CHO (NHS-PEG3400-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
- HY-174948A
-
|
NHS-PEG2000-Aldehyde
|
Biochemical Assay Reagents
|
|
NHS-PEG2000-CHO (NHS-PEG2000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
- HY-174891
-
|
|
Biochemical Assay Reagents
|
|
Betiatide-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
|
- HY-182833A
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG2000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
|
- HY-182833D
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG10000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG10000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
|
- HY-182833B
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG3400-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
|
- HY-183104D
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG10000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG10000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
|
- HY-183104
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG1000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
|
- HY-183016
-
|
|
Biochemical Assay Reagents
|
|
DMPE-PEG1000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
|
- HY-183104B
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG3400-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
|
- HY-183104A
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG2000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
|
- HY-183016C
-
|
|
Biochemical Assay Reagents
|
|
DMPE-PEG5000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
|
- HY-183016B
-
|
|
Biochemical Assay Reagents
|
|
DMPE-PEG3400-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
|
- HY-182833
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG1000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
|
- HY-183104C
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG5000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
|
- HY-182833C
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG5000-NHS is a conjugate composed of DPPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
|
- HY-183016A
-
|
|
Biochemical Assay Reagents
|
|
DMPE-PEG2000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
|
- HY-183016D
-
|
|
Biochemical Assay Reagents
|
|
DMPE-PEG10000-NHS is a conjugate composed of DMPE, PEG chains, and terminal active esters (NHS). The NHS ester in DMPE-PEG10000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
|
- HY-183162A
-
|
|
Biochemical Assay Reagents
|
|
Glucose-PEG2000-NHS is a conjugate composed of glucose, PEG chains, and an active ester (NHS). Glucose-PEG2000-NHS combines the targeted recognition capabilities of glucose with the ability to rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and amino-modified small molecules) to form stable amide bonds in an NHS ester. This allows for applications such as constructing targeted drug delivery systems and modifying nanoparticles.
|
- HY-183162D
-
|
|
Biochemical Assay Reagents
|
|
Glucose-PEG10000-NHS is a conjugate composed of glucose, PEG chains, and an active ester (NHS). Glucose-PEG10000-NHS combines the targeted recognition capabilities of glucose with the ability to rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and amino-modified small molecules) to form stable amide bonds in an NHS ester. This allows for applications such as constructing targeted drug delivery systems and modifying nanoparticles.
|
- HY-183162C
-
|
|
Biochemical Assay Reagents
|
|
Glucose-PEG5000-NHS is a conjugate composed of glucose, PEG chains, and an active ester (NHS). Glucose-PEG5000-NHS combines the targeted recognition capabilities of glucose with the ability to rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and amino-modified small molecules) to form stable amide bonds in an NHS ester. This allows for applications such as constructing targeted drug delivery systems and modifying nanoparticles.
|
- HY-183162B
-
|
|
Biochemical Assay Reagents
|
|
Glucose-PEG3400-NHS is a conjugate composed of glucose, PEG chains, and an active ester (NHS). Glucose-PEG3400-NHS combines the targeted recognition capabilities of glucose with the ability to rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and amino-modified small molecules) to form stable amide bonds in an NHS ester. This allows for applications such as constructing targeted drug delivery systems and modifying nanoparticles.
|
- HY-183162
-
|
|
Biochemical Assay Reagents
|
|
Glucose-PEG1000-NHS is a conjugate composed of glucose, PEG chains, and an active ester (NHS). Glucose-PEG1000-NHS combines the targeted recognition capabilities of glucose with the ability to rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and amino-modified small molecules) to form stable amide bonds in an NHS ester. This allows for applications such as constructing targeted drug delivery systems and modifying nanoparticles.
|
- HY-203300D
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG1000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
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- HY-203300C
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG5000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
|
- HY-203300B
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG3400-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
|
- HY-203300A
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG1000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
|
- HY-203300
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG2000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
|
- HY-174895
-
|
|
Biochemical Assay Reagents
|
|
Propargyl-PEG12-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
|
- HY-W588715C
-
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|
Biochemical Assay Reagents
|
|
Acid-PEG1-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
|
- HY-174889
-
|
|
Biochemical Assay Reagents
|
|
Acetal-PEG18-NHS is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
|
- HY-174892A
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG32-NHS ester is a PEG derivative composed of Biotin, 32 PEG units, and NHS ester. Biotin can form a stable non-covalent bond with streptavidin. NHS ester can bind to amino acids or other molecules containing amino groups .
|
- HY-W1120356A
-
- HY-126908A
-
|
|
Biochemical Assay Reagents
|
|
Tetrazine-Ph-PEG17-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
|
- HY-174264A
-
- HY-174897
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG4-NHS ester is a lipid-containing PEG derivative that can be used to form micelles as nanoparticles for drug delivery . NHS esters can be conjugated to amino acids or other molecules containing an amino group.
|
- HY-183134A
-
|
|
Biochemical Assay Reagents
|
|
C16-PEG3400-NHS is a conjugate composed of hexadecyl (C16, i.e., palmitoyl), a PEG chain, and an active ester (NHS). C16-PEG3400-NHS combines the membrane compatibility of lipids with glucose as an active site for sugar recognition or subsequent conjugation reactions, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183169B
-
|
|
Biochemical Assay Reagents
|
|
C18-PEG5000-NHS is a conjugate composed of octadecyl (C18 aliphatic chain), PEG chains, and an active ester (NHS). C18-PEG5000-NHS combines the membrane compatibility of lipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183134B
-
|
|
Biochemical Assay Reagents
|
|
C16-PEG5000-NHS is a conjugate composed of hexadecyl (C16, i.e., palmitoyl), a PEG chain, and an active ester (NHS). C16-PEG5000-NHS combines the membrane compatibility of lipids with glucose as an active site for sugar recognition or subsequent conjugation reactions, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183169
-
|
|
Biochemical Assay Reagents
|
|
C18-PEG2000-NHS is a conjugate composed of octadecyl (C18 aliphatic chain), PEG chains, and an active ester (NHS). C18-PEG2000-NHS combines the membrane compatibility of lipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183169A
-
|
|
Biochemical Assay Reagents
|
|
C18-PEG3400-NHS is a conjugate composed of octadecyl (C18 aliphatic chain), PEG chains, and an active ester (NHS). C18-PEG3400-NHS combines the membrane compatibility of lipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183134
-
|
|
Biochemical Assay Reagents
|
|
C16-PEG2000-NHS is a conjugate composed of hexadecyl (C16, i.e., palmitoyl), a PEG chain, and an active ester (NHS). C16-PEG2000-NHS combines the membrane compatibility of lipids with glucose as an active site for sugar recognition or subsequent conjugation reactions, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-174894
-
|
|
Biochemical Assay Reagents
|
|
Azido-PEG11-NHS ester is a PEG derivative that can be used for drug delivery and other research. Azido-PEG11-NHS ester is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group. It can also undergo ring strain driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
|
- HY-W1048603D
-
|
|
Biochemical Assay Reagents
|
|
4-arm PEG600-NHS is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
- HY-W1048603H
-
|
|
Biochemical Assay Reagents
|
|
4-arm PEG2000-NHS is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
- HY-W1048603I
-
|
|
Biochemical Assay Reagents
|
|
4-arm PEG3400-NHS is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
- HY-W1048603A
-
|
|
Biochemical Assay Reagents
|
|
4-arm PEG10000-NHS is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
- HY-W1048512D
-
|
|
Biochemical Assay Reagents
|
|
2-Arm PEG10000-NHS is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
- HY-174959E
-
|
|
Biochemical Assay Reagents
|
|
6-Arm-PEG5000-NHS is a six-arm PEG derivative that can be used for peptide modification and drug delivery .
|
- HY-174959A
-
|
|
Biochemical Assay Reagents
|
|
6-Arm-PEG600-NHS is a six-arm PEG derivative that can be used for peptide modification and drug delivery .
|
- HY-W1048512B
-
|
|
Biochemical Assay Reagents
|
|
2-Arm PEG40000-NHS is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
- HY-W1048603C
-
|
|
Biochemical Assay Reagents
|
|
4-arm PEG400-NHS is a multi-arm PEG derivative that can be used for peptide modification and drug delivery .
|
- HY-128890A
-
|
|
Biochemical Assay Reagents
|
|
DOTA-NHS-ester (hexafluorophosphate TFA)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-NHS-ester (hexafluorophosphate TFA) can be used for conjugation of peptides and radionuclides.
|
- HY-174264
-
|
|
Biochemical Assay Reagents
|
|
DMG-PEG2000-NHS is a polyethylene glycol lipid with a molecular weight of 2000, which can be used to construct novel drug delivery systems that confer mucoadhesive and cell-targeting capabilities to lipid nanoparticles .
|
- HY-W441015A
-
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|
Biochemical Assay Reagents
|
|
DSPE-m-PEG3400-NHS is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine .
|
- HY-W441014C
-
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|
Biochemical Assay Reagents
|
|
DSPE-PEG40000-NHS ammonium is one of the most commonly used reactive phospholipids for coupling antibodies, proteins, peptides or other substrates to the surface of liposomes and other lipid PEG nanoparticles .
|
- HY-W441014B
-
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|
Biochemical Assay Reagents
|
|
DSPE-PEG20000-NHS ammonium is one of the most commonly used reactive phospholipids for coupling antibodies, proteins, peptides or other substrates to the surface of liposomes and other lipid PEG nanoparticles .
|
- HY-W441014A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG10000-NHS ammonium is one of the most commonly used reactive phospholipids for coupling antibodies, proteins, peptides or other substrates to the surface of liposomes and other lipid PEG nanoparticles .
|
- HY-W440928
-
|
|
Biochemical Assay Reagents
|
|
Stearic acid-PEG3400-NHS is a phospholipid polyPEG which can self-assemble in water to form lipid bilayer. The polymer can be used to prepare liposomes as drug carrier to deliver nutrients/therpeutic agents, such as mRNA or DNA.
|
- HY-W591424
-
|
mPEG2000-SC; mPEG2000-Succinimidyl ester
|
Biochemical Assay Reagents
|
|
m-PEG2000-NHS ester (mPEG2000-SC) is a reagent with both cell adhesion inhibition and peptide conjugation functions. The NHS ester group of m-PEG2000-NHS ester forms stable amide bonds with primary amine-containing molecules (e.g., the N-terminus of MMP-2-cleavable octapeptide) to generate mPEG-peptide intermediates for liposome surface modification. When m-PEG2000-NHS ester is immobilized on a cystamine-modified gold surface, it can construct an in vitro model for cell adhesion kinetic studies, and higher PEG density and thicker layers correlate with lower cell adhesion rates. m-PEG2000-NHS ester can synthesize MMP-2-responsive PEGylated lipid conjugates to achieve MMP-triggered dePEGylation in the tumor microenvironment. m-PEG2000-NHS ester can be used in studies related to colon cancer and other conditions .
|
- HY-W544595
-
- HY-140700
-
|
mPEG20000-SC; mPEG20000-Succinimidyl ester
|
Biochemical Assay Reagents
|
|
m-PEG20000-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-140699
-
|
mPEG10000-SC; mPEG10000-Succinimidyl ester
|
Biochemical Assay Reagents
|
|
m-PEG10000-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-140698
-
|
mPEG5000-SC; mPEG5000-Succinimidyl ester
|
Biochemical Assay Reagents
|
|
m-PEG5000-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-W143136
-
- HY-155909A
-
|
mPEG1000-SC; mPEG1000-Succinimidyl ester
|
Biochemical Assay Reagents
|
|
m-PEG1000-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
- HY-155909C
-
|
mPEG350-SC; mPEG350-Succinimidyl ester
|
Biochemical Assay Reagents
|
|
m-PEG350-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
- HY-155909B
-
|
mPEG550-SC; mPEG550-Succinimidyl ester
|
Biochemical Assay Reagents
|
|
m-PEG550-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
- HY-155909
-
|
mPEG3400-SC; mPEG3400-Succinimidyl ester
|
Biochemical Assay Reagents
|
|
m-PEG3400-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
- HY-W440926
-
|
|
Biochemical Assay Reagents
|
|
Stearic acid-PEG1000-NHS is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond.
|
- HY-136158A
-
|
Sulfo-EMCS
|
Biochemical Assay Reagents
|
|
6-Maleimidocaproic acid sulfo-NHS (Sulfo-EMCS) sodium is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-W105423
-
|
NHS-MA
|
Biochemical Assay Reagents
|
|
Methacrylic acid N-hydroxysuccinimide ester (NHS-MA) is a polymer that serves as a monomer to prepare degradable amphiphilic block copolymer microparticles via RAFT polymerization for low pH-triggered drug delivery. Methacrylic acid N-hydroxysuccinimide ester is used for the synthesis of nanogels .
|
- HY-W123004
-
|
N-Hydroxy-succinimidy-propionate octa(ethylene glycol)-disulfid
|
Biochemical Assay Reagents
|
|
PEG NHS ester disulfide (N-Hydroxy-succinimidy-propionate octa(ethylene glycol)-disulfid) is a biochemical reagent.
|
- HY-W591384
-
|
|
Biochemical Assay Reagents
|
|
Boc-NH-PEG12-NHS ester is a PEG derivative composed of NHS ester, which can be conjugated to amino acids or other molecules containing amino groups.
|
- HY-W1049085H
-
|
mPEG-Succinimidyl Succinate ester (MW 3400)
|
Biochemical Assay Reagents
|
|
mPEG-SS (MW 3400) (mPEG-Succinimidyl Succinate ester (MW 3400)) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG-SS (MW 3400) can be used for drug delivery .
|
- HY-W1049085C
-
|
mPEG20000-Succinimidyl Succinate ester
|
Biochemical Assay Reagents
|
|
mPEG20000-SS (mPEG20000-Succinimidyl Succinate ester) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG20000-SS can be used for drug delivery .
|
- HY-W1049085B
-
|
mPEG10000-Succinimidyl Succinate ester
|
Biochemical Assay Reagents
|
|
mPEG10000-SS (mPEG10000-Succinimidyl Succinate ester) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG10000-SS can be used for drug delivery .
|
- HY-W1049085E
-
|
mPEG2000-Succinimidyl Succinate ester
|
Biochemical Assay Reagents
|
|
mPEG2000-SS (mPEG2000-Succinimidyl Succinate ester) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG2000-SS can be used for drug delivery .
|
- HY-W1049085D
-
|
mPEG40000-Succinimidyl Succinate ester
|
Biochemical Assay Reagents
|
|
mPEG40000-SS (mPEG40000-Succinimidyl Succinate ester) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG40000-SS can be used for drug delivery .
|
- HY-W1049085
-
|
mPEG1000-Succinimidyl Succinate ester
|
Biochemical Assay Reagents
|
|
mPEG1000-SS (mPEG1000-Succinimidyl Succinate ester) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG1000-SS can be used for drug delivery .
|
- HY-W1049085A
-
|
mPEG5000-Succinimidyl Succinate ester
|
Biochemical Assay Reagents
|
|
mPEG5000-SS (mPEG5000-Succinimidyl Succinate ester) is a mPEG-NHS ester reagent with a C2 aliphatic ester bond between PEG and NHS ester. mPEG5000-SS can be used for drug delivery .
|
- HY-D0975
-
|
|
Biochemical Assay Reagents
|
|
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
|
- HY-W1048567
-
|
|
Biochemical Assay Reagents
|
|
mPEG1000-SCM is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .
|
- HY-W1048567B
-
|
|
Biochemical Assay Reagents
|
|
mPEG5000-SCM is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .
|
- HY-W1048567E
-
|
|
Biochemical Assay Reagents
|
|
mPEG40000-SCM is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .
|
- HY-W1048567D
-
|
|
Biochemical Assay Reagents
|
|
mPEG20000-SCM is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .
|
- HY-W1048567C
-
|
|
Biochemical Assay Reagents
|
|
mPEG10000-SCM is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .
|
- HY-W1048567A
-
|
|
Biochemical Assay Reagents
|
|
mPEG2000-SCM is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .
|
- HY-W1048567H
-
|
|
Biochemical Assay Reagents
|
|
mPEG3400-SCM is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .
|
- HY-W011412
-
|
|
Biochemical Assay Reagents
|
|
TSTU is used as a coupling reagent in peptide chemistry. TSTU can convert carboxylic acids into the corresponding N-hydroxysuccinimidyl (NHS) esters. TSTU can be applied to the attachment of labels to peptides, proteins, etc .
|
- HY-W441002
-
|
|
Biochemical Assay Reagents
|
|
DSPE-succinic acid is a derivative of Succinic acid (HY-N0420) and an intermediate of DSPE-Doxorubicin. DSPE-succinic acid can be used to synthesize DSPE-Doxorubicin via EDC/NHS activation. DSPE-succinic acid is applicable to the research of triple-negative breast cancer .
|
- HY-155885
-
|
mPEG40000-NH2
|
Biochemical Assay Reagents
|
|
mPEG40000-amine (mPEG40000-NH2) is a monofunctional polyPEG with a terminal amine. The coupling between NHS ester and amine produces a stable amide bond. The amine moieties is also reactive with carboxyl in the presence of activating agent .
|
- HY-W793100
-
|
|
Biochemical Assay Reagents
|
|
Endo-BCN-PEG2-Biotin is a PEG linker containing a BCN group and a terminal carboxylic acid. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
- HY-172270D
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
- HY-172270C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
- HY-172270
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
- HY-172270A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
- HY-W1048553C
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG5000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
- HY-W1048553H
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG40000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
- HY-W1048553A
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG2000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
- HY-W1048553B
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG3400-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
- HY-W1048553E
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG20000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
- HY-W1048553
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG1000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
- HY-W1048553D
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG10000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
- HY-W879032
-
|
|
Biochemical Assay Reagents
|
|
Endo-BCN-PEG4-Pomalidomide is a PEG derivative composed of BCN, PEG4 and Pomalidomide (HY-10984). The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
- HY-200288B
-
|
|
Biochemical Assay Reagents
|
|
DMG-PEG3400-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG3400-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-W1052117A
-
|
|
Biochemical Assay Reagents
|
|
DMPE-PEG3400-COOH is a conjugate composed of DMPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMPE-PEG3400-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-W1052873C
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG1000-COOH is a conjugate composed of DPPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DPPE-PEG1000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-W1052117
-
|
|
Biochemical Assay Reagents
|
|
DMPE-PEG2000-COOH is a conjugate composed of DMPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMPE-PEG2000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-183173D
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG10000-COOH is a conjugate composed of DSG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSG-PEG10000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-200288D
-
|
|
Biochemical Assay Reagents
|
|
DMG-PEG10000-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG10000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-W1052873B
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG5000-COOH is a conjugate composed of DPPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DPPE-PEG5000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-W1052873A
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG3400-COOH is a conjugate composed of DPPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DPPE-PEG3400-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-W1052117C
-
|
|
Biochemical Assay Reagents
|
|
DMPE-PEG1000-COOH is a conjugate composed of DMPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMPE-PEG1000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-183173C
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG5000-COOH is a conjugate composed of DSG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSG-PEG5000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-183173B
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG3400-COOH is a conjugate composed of DSG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSG-PEG3400-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-183173
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG1000-COOH is a conjugate composed of DSG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSG-PEG1000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-W1052873D
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG10000-COOH is a conjugate composed of DPPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DPPE-PEG10000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-200288
-
|
|
Biochemical Assay Reagents
|
|
DMG-PEG2000-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG2000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-183173A
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG2000-COOH is a conjugate composed of DSG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSG-PEG2000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-200288A
-
|
|
Biochemical Assay Reagents
|
|
DMG-PEG1000-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG1000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-W1052873
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG2000-COOH is a conjugate composed of DPPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DPPE-PEG2000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-W1052117D
-
|
|
Biochemical Assay Reagents
|
|
DMPE-PEG1000-COOH is a conjugate composed of DMPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMPE-PEG1000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-200288C
-
|
|
Biochemical Assay Reagents
|
|
DMG-PEG5000-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG5000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-W1052117B
-
|
|
Biochemical Assay Reagents
|
|
DMPE-PEG5000-COOH is a conjugate composed of DMPE, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMPE-PEG5000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
|
- HY-W879044
-
|
Endo-BCN-PEG15-NH2
|
Biochemical Assay Reagents
|
|
Endo-BCN-PEG15-amine (Endo-BCN-PEG15-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
- HY-W879025
-
|
Endo-BCN-PEG8-NH2
|
Biochemical Assay Reagents
|
|
Endo-BCN-PEG8-amine (Endo-BCN-PEG8-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
- HY-W879045
-
|
Endo-BCN-PEG5-NH2
|
Biochemical Assay Reagents
|
|
Endo-BCN-PEG5-amine (Endo-BCN-PEG5-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
- HY-140895B
-
|
Biotin-PEG10000-NH2
|
Biochemical Assay Reagents
|
|
Biotin-PEG10000-Amine (Biotin-PEG10000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
- HY-140895C
-
|
Biotin-PEG20000-NH2
|
Biochemical Assay Reagents
|
|
Biotin-PEG20000-Amine (Biotin-PEG20000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
- HY-140895D
-
|
Biotin-PEG40000-NH2
|
Biochemical Assay Reagents
|
|
Biotin-PEG40000-Amine (Biotin-PEG40000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
- HY-140895A
-
|
Biotin-PEG5000-NH2
|
Biochemical Assay Reagents
|
|
Biotin-PEG5000-Amine (Biotin-PEG5000-NH2) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .
|
- HY-W1052523C
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG1000-NH2 is a conjugate composed of DPPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DPPE-PEG1000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
|
- HY-W1052523B
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG5000-NH2 is a conjugate composed of DPPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DPPE-PEG5000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
|
- HY-W1052523
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG2000-NH2 is a conjugate composed of DPPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DPPE-PEG2000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
|
- HY-W1052523D
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG10000-NH2 is a conjugate composed of DPPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DPPE-PEG10000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
|
- HY-W1052523A
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG3400-NH2 is a conjugate composed of DPPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DPPE-PEG3400-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
|
- HY-W1048525B
-
|
8-Arm PEG40000-Amine
|
Biochemical Assay Reagents
|
|
8-Arm PEG40000-NH2 (8-Arm PEG40000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1048526
-
|
8-Arm PEG5000-amine HCL salt
|
Biochemical Assay Reagents
|
|
8-Arm PEG5000-NH2 (8-Arm PEG5000-amine) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1048526C
-
|
8-Arm PEG10000-amine HCL salt
|
Biochemical Assay Reagents
|
|
8-Arm PEG10000-NH2 (8-Arm PEG10000-amine) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1048525C
-
|
8-Arm PEG10000-Amine
|
Biochemical Assay Reagents
|
|
8-Arm PEG10000-NH2 (8-Arm PEG10000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1048526B
-
|
8-Arm PEG40000-amine HCL salt
|
Biochemical Assay Reagents
|
|
8-Arm PEG40000-NH2 (8-Arm PEG40000-amine) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1048526A
-
|
8-Arm PEG20000-amine HCL salt
|
Biochemical Assay Reagents
|
|
8-Arm PEG20000-NH2 (8-Arm PEG20000-amine) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1048525
-
|
8-Arm PEG5000-Amine
|
Biochemical Assay Reagents
|
|
8-Arm PEG5000-NH2 (8-Arm PEG5000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1048525A
-
|
8-Arm PEG20000-Amine
|
Biochemical Assay Reagents
|
|
8-Arm PEG20000-NH2 (8-Arm PEG20000-Amine) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1048843B
-
|
4-Arm PEG10000-amine
|
Biochemical Assay Reagents
|
|
4-Arm PEG10000-NH2 (4-Arm PEG10000-amine) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1048555B
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG3400-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG3400-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
- HY-W1048843A
-
|
4-Arm PEG5000-amine
|
Biochemical Assay Reagents
|
|
4-Arm PEG5000-NH2 (4-Arm PEG5000-amine) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1048555D
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG10000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG10000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
- HY-W1048555H
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG40000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG40000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
- HY-W1048519B
-
|
4-Arm PEG20000-amine HCL salt
|
Biochemical Assay Reagents
|
|
4-Arm PEG20000-NH2 (4-Arm PEG20000-amine) hydrochloride is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1048843C
-
|
4-Arm PEG20000-amine
|
Biochemical Assay Reagents
|
|
4-Arm PEG20000-NH2 (4-Arm PEG20000-amine) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1052298
-
|
DMPE-PEG2000-Amine
|
Biochemical Assay Reagents
|
|
DMPE-PEG2000-NH2 (DMPE-PEG2000-Amine) is a conjugate composed of DMPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DMPE-PEG2000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
|
- HY-W1048519C
-
|
4-Arm PEG40000-amine HCL salt
|
Biochemical Assay Reagents
|
|
4-Arm PEG40000-NH2 (4-Arm PEG40000-amine) hydrochloride is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1048572E
-
|
|
Biochemical Assay Reagents
|
|
N3-PEG5000-NH2 is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG5000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
|
- HY-W1048572A
-
|
|
Biochemical Assay Reagents
|
|
N3-PEG2000-NH2 is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG2000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
|
- HY-W1048555C
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG5000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG5000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
- HY-W1048519
-
|
4-Arm PEG5000-amine HCL salt
|
Biochemical Assay Reagents
|
|
4-Arm PEG5000-NH2 (4-Arm PEG5000-amine) hydrochloride is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1052298B
-
|
DMPE-PEG5000-Amine
|
Biochemical Assay Reagents
|
|
DMPE-PEG5000-NH2 (DMPE-PEG5000-Amine) is a conjugate composed of DMPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DMPE-PEG5000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
|
- HY-W1048843D
-
|
4-Arm PEG40000-amine
|
Biochemical Assay Reagents
|
|
4-Arm PEG40000-NH2 (4-Arm PEG40000-amine) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1052298D
-
|
DMPE-PEG10000-Amine
|
Biochemical Assay Reagents
|
|
DMPE-PEG2000-NH2 (DMPE-PEG2000-Amine) is a conjugate composed of DMPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DMPE-PEG2000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
|
- HY-W1048519A
-
|
4-Arm PEG10000-amine HCL salt
|
Biochemical Assay Reagents
|
|
4-Arm PEG10000-NH2 (4-Arm PEG100000-amine) hydrochloride is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1052298A
-
|
DMPE-PEG3400-Amine
|
Biochemical Assay Reagents
|
|
DMPE-PEG3400-NH2 (DMPE-PEG3400-Amine) is a conjugate composed of DMPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DMPE-PEG3400-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
|
- HY-W1048555E
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG20000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG20000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
- HY-W1048555
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG1000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG1000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
- HY-W1052298C
-
|
DMPE-PEG1000-Amine
|
Biochemical Assay Reagents
|
|
DMPE-PEG1000-NH2 (DMPE-PEG1000-Amine) is a conjugate composed of DMPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DMPE-PEG1000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
|
- HY-183133B
-
|
|
Biochemical Assay Reagents
|
|
C16-PEG5000-COOH is a conjugate composed of a hexadecyl (C16 aliphatic chain), a PEG chain, and a carboxyl group (-COOH). C16-PEG5000-COOH combines the membrane compatibility of lipids with the carboxyl group, which can form amide bonds with primary amines via EDC/NHS activation, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183168B
-
|
|
Biochemical Assay Reagents
|
|
C18-PEG5000-COOH is a conjugate composed of an octadecyl group (C18 aliphatic chain), a PEG chain, and a carboxyl group (-COOH). C18-PEG5000-COOH combines the membrane compatibility of lipids with the carboxyl group, which can form amide bonds with primary amines via EDC/NHS activation, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183133A
-
|
|
Biochemical Assay Reagents
|
|
C16-PEG3400-COOH is a conjugate composed of a hexadecyl (C16 aliphatic chain), a PEG chain, and a carboxyl group (-COOH). C16-PEG3400-COOH combines the membrane compatibility of lipids with the carboxyl group, which can form amide bonds with primary amines via EDC/NHS activation, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183168A
-
|
|
Biochemical Assay Reagents
|
|
C18-PEG3400-COOH is a conjugate composed of an octadecyl group (C18 aliphatic chain), a PEG chain, and a carboxyl group (-COOH). C18-PEG3400-COOH combines the membrane compatibility of lipids with the carboxyl group, which can form amide bonds with primary amines via EDC/NHS activation, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183168
-
|
|
Biochemical Assay Reagents
|
|
C18-PEG2000-COOH is a conjugate composed of an octadecyl group (C18 aliphatic chain), a PEG chain, and a carboxyl group (-COOH). C18-PEG2000-COOH combines the membrane compatibility of lipids with the carboxyl group, which can form amide bonds with primary amines via EDC/NHS activation, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183133
-
|
|
Biochemical Assay Reagents
|
|
C16-PEG2000-COOH is a conjugate composed of a hexadecyl (C16 aliphatic chain), a PEG chain, and a carboxyl group (-COOH). C16-PEG2000-COOH combines the membrane compatibility of lipids with the carboxyl group, which can form amide bonds with primary amines via EDC/NHS activation, making it suitable for research in biomaterial construction and drug delivery.
|
- HY-W1048572C
-
|
Azide-PEG1000-Amine
|
Biochemical Assay Reagents
|
|
N3-PEG1000-NH2 (Azide-PEG1000-Amine) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG1000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
|
- HY-W1048572H
-
|
Azide-PEG10000-Amine
|
Biochemical Assay Reagents
|
|
N3-PEG10000-NH2 (Azide-PEG10000-Amine) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG10000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
|
- HY-W1048572I
-
|
Azide-PEG20000-Amine
|
Biochemical Assay Reagents
|
|
N3-PEG20000-NH2 (Azide-PEG20000-Amine) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG20000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
|
- HY-42972G
-
|
|
Biochemical Assay Reagents
|
|
DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester ((HY-115524) and (HY-115545)), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
- HY-W1048572D
-
|
Azide-PEG3400-Amine
|
Biochemical Assay Reagents
|
|
N3-PEG3400-NH2 (Azide-PEG3400-Amine) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG3400-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
|
- HY-W1048572J
-
|
Azide-PEG40000-Amine
|
Biochemical Assay Reagents
|
|
N3-PEG40000-NH2 (Azide-PEG40000-Amine) is a hetero-bifunctional PEG product with an azide and an amine group at the PEG terminus. N3-PEG40000-NH2 is an important cross-linker with PEG chains. The azide can be used for molecular conjugation through chemical reactions, and the amine can react with carboxylic acid or NHS ester .
|
- HY-W1048547A
-
|
HOOC-PEG2000-Amine
|
Biochemical Assay Reagents
|
|
HOOC-PEG2000-NH2 (HOOC-PEG2000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
- HY-W1048547J
-
|
HOOC-PEG40000-Amine
|
Biochemical Assay Reagents
|
|
HOOC-PEG40000-NH2 (HOOC-PEG40000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
- HY-W1048547H
-
|
HOOC-PEG1000-Amine
|
Biochemical Assay Reagents
|
|
HOOC-PEG1000-NH2 (HOOC-PEG1000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
- HY-W1048547E
-
|
HOOC-PEG20000-Amine
|
Biochemical Assay Reagents
|
|
HOOC-PEG20000-NH2 (HOOC-PEG20000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
- HY-W1048547I
-
|
HOOC-PEG3400-Amine
|
Biochemical Assay Reagents
|
|
HOOC-PEG3400-NH2 (HOOC-PEG3400-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
- HY-W1048547C
-
|
HOOC-PEG5000-Amine
|
Biochemical Assay Reagents
|
|
HOOC-PEG5000-NH2 (HOOC-PEG5000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
- HY-W1048547D
-
|
HOOC-PEG10000-Amine
|
Biochemical Assay Reagents
|
|
HOOC-PEG10000-NH2 (HOOC-PEG10000-Amine) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
- HY-W1048843AG
-
|
4-Arm PEG5000-amine
|
Biochemical Assay Reagents
|
|
4-Arm PEG5000-NH2 (GMP) (4-Arm PEG5000-amine (GMP)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
- HY-W1048843AGL
-
|
4-Arm PEG5000-amine (GMP Like)
|
Biochemical Assay Reagents
|
|
4-Arm PEG5000-NH2 (GMP Like) (4-Arm PEG5000-amine (GMP Like)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP like guidelines. GMP like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-K0227
-
|
|
|
MCE NHS Magnetic Beads (200 nm, 10 mg/mL) contain N-hydroxysuccinimide (NHS) functional groups, which react with primary amines on proteins or
other molecules to form stable amide linkages，can covalently immobilize proteins for the affinity purification of antibodies, antigens and other
biomolecules.
|
-
- HY-KD1113
-
|
|
|
The Biotinylation Rapid Labelling Kit enables biotinylation of proteins. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled within a pH 7-9 solution, forming stable amide bonds to achieve conjugation with the antibody/protein. Typically, a single IgG molecule can bind 2-8 molecules of biotin. The entire procedure can be completed within two hours.
|
-
- HY-KD1115
-
|
|
|
The DOTA rapid labelling kit enables DOTA labelling of proteins. Based on NHS ester chemistry, NHS ester-activated fluorescent dyes react with primary amines on the antibody/protein to form stable amide bonds at pH 7–9, thereby achieving conjugation with the antibody/protein. Typically, a single IgG molecule can bind 2–8 DOTA molecules. The entire procedure can be completed within 2 hours.
|
-
- HY-KD1114
-
|
|
|
The NOTA Rapid Labelling Kit enables NOTA labelling of proteins. Based on NHS ester chemistry, NHS ester-activated fluorescent dyes react with primary amines on the antibody/protein to be labelled in a pH 7-9 solution, forming stable amide bonds to achieve conjugation with the antibody/protein. Typically, a single IgG molecule can bind 2–8 NOTA molecules. The entire procedure can be completed within two hours.
|
-
- HY-KD1101
-
|
|
|
Green Fluorescent Rapid Labelling Kit (FITC) enables green fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 488/515 nm. Based on NHS-ester chemistry, the NHS-ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds, thereby achieving conjugation with antibodies/proteins. Typically, one IgG molecule can bind 2-8 molecules of FITC. The entire procedure can be completed within two hours.
|
-
- HY-KD1106
-
|
|
|
Red Fluorescent Rapid Labelling Kit (AF647) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 647/665 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2-8 molecules of AF647. The entire procedure can be completed within two hours.
|
-
- HY-KD1112
-
|
|
|
TheBlue Fluorescence Rapid Labelling Kit (AF350) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 346/442 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2-8 molecules of AF350. The entire procedure can be completed within two hours.
|
-
- HY-KD1103
-
|
|
|
Red Fluorescent Rapid Labelling Kit (CY3) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 550/570 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation with the antibody/protein. Typically, one IgG molecule can bind 2–8 molecules of CY3. The entire experiment can be completed within 2 hours.
|
-
- HY-KD1107
-
|
|
|
Deep Red Fluorescent Rapid Labelling Kit (CY5) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 649/667 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2–8 molecules of CY5. The entire experiment can be completed within 2 hours.
|
-
- HY-KD1111
-
|
|
|
Near-infrared Fluorescent Rapid Labelling Kit (AF750) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 750/775 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds, thereby achieving conjugation with antibodies/proteins. Typically, one IgG molecule can bind 2-8 molecules of AF750. The entire procedure can be completed within two hours.
|
-
- HY-KD1102
-
|
|
|
Green Fluorescent Rapid Labelling Kit (AF488) enables green fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 480/525 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds, thereby achieving conjugation with antibodies/proteins. Typically, one IgG molecule can bind 2-8 molecules of AF488. The entire procedure can be completed within two hours.
|
-
- HY-KD1105
-
|
|
|
Red Fluorescent Rapid Labelling Kit (AF594) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 594/617 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds, thereby achieving conjugation with antibodies/proteins. Typically, one IgG molecule can bind 2-8 molecules of AF594. The entire procedure can be completed within two hours.
|
-
- HY-KD1104
-
|
|
|
Red Fluorescent Rapid Labelling Kit (AF555) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 555/565 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds with the target antibody/protein, achieving conjugation. Typically, one IgG molecule can bind 2-8 molecules of AF555. The entire procedure can be completed within two hours.
|
-
- HY-KD1109
-
|
|
|
Near-infrared Fluorescent Rapid Labelling Kit (CY7) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 750/773 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2–8 molecules of CY7. The entire experiment can be completed within 2 hours.
|
-
- HY-KD1108
-
|
|
|
Deep Red Fluorescent Rapid Labelling Kit (CY5.5) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 678/695 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2-8 molecules of CY5.5. The entire procedure can be completed within two hours.
|
-
- HY-KD1110
-
|
|
|
The Near-Infrared Fluorescence Rapid Labelling Kit (CY7.5) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 788/814 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2-8 molecules of CY7.5. The entire procedure can be completed within two hours.
|
| Cat. No. |
Product Name |
Target |
Research Area |
Image |
-
- HY-P99239
-
|
HUJ-591; TLX591
|
PSMA
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
Rosopatamab (HuJ591) is a humanized antiPSMA IgG1 monoclonal antibody that can be used in cancer research, especially prostate cancer. Rosopatamab can be linked to the low-energy beta-emitting radioisotope lutetium-177 ( 177Lu) through the bifunctional chelator DOTA-NHS ester to obtain a radioimmunoconjugate that targets malignant prostate cells with high efficiency .
|
-
(5)
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N16296
-
|
|
Structural Classification
Lipid
|
Fluorescent Dye
|
|
Cy7.5 NHS ester chloride is a fluorescent dye. Cy7.5 NHS ester chloride can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester chloride can be used for fluorescent imaging study (Ex/Em = 780/820 nm) .
|
-
-
- HY-D1596B
-
|
(E)-Cy3.5 NHS ester chloride; (E)-Cy 3.5 chloride
|
Lipid
|
Fluorescent Dye
|
|
(E)-Cyanine 3.5 ((E)-Cy3.5 NHS ester) chloride is a cyanine dye functionalized with a N-hydroxysuccinimide (NHS) group. (E)-Cyanine 3.5 chloride contains NHS groups that react with ammonia to form ester bonds (Ex/Em = 586/612 nm).
|
-
-
- HY-N15975
-
|
|
Lipid
|
Biochemical Assay Reagents
|
|
12:0 N-Biotinyl fatty acid, NHS is a biotinylated lipid. 12:0 N-Biotinyl fatty acid, NHS contains NHS groups that react with ammonia to form ester bonds .
|
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-118431S3
-
|
|
|
DMABA-d10 NHS ester is the deuterium labeled DMABA NHS ester .
|
-
-
- HY-118431S2
-
|
|
|
DMABA-d6 NHS ester is the deuterium labeled DMABA NHS ester .
|
-
-
- HY-118431S
-
|
|
|
DMABA-d4 NHS ester is the deuterium labeled DMABA NHS ester .
|
-
-
- HY-145547S
-
|
|
|
1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine-d27 (14:0 Lyso PE-d27) is the deuterium labeled 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine. 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-140272
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-42973
-
|
|
|
ADC Synthesis
DBCO
|
|
DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-151835
-
|
|
|
DBCO
|
|
DBCO-PEG24-NHS ester is a click chemistry reagent. DBCO-PEG24-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .
|
-
- HY-140273
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG8-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-141269
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W035129
-
|
|
|
BCN
|
|
endo-BCN-NHS carbonate is an elastin-like protein (ELP) modification reagent. endo-BCN-NHS carbonate can react with lysine residues in ELP to make ELP carry BCN groups, and then cross-link ELP through strain-promoted azide-alkyne cycloaddition (SPAAC) reaction. endo-BCN-NHS carbonate promotes hydrogel formation. endo-BCN-NHS carbonate is mainly used in cell encapsulation related research .
|
-
- HY-126521
-
|
|
|
ADC Synthesis
Azide
|
|
N3-C3-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-115524
-
|
|
|
DBCO
ADC Synthesis
|
|
DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry[1]. DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140274
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG12-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-126513
-
|
|
|
ADC Synthesis
Alkynes
|
|
Propargyl-PEG1-NHS ester is a nonclaevable 1-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-PEG1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130184
-
|
|
|
Azide
PROTAC Synthesis
ADC Synthesis
|
|
Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG8-NHS ester is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140755
-
|
|
|
Azide
PROTAC Synthesis
|
|
Aeide-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Aeide-C1-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-123687
-
|
|
|
DBCO
ADC Synthesis
|
|
DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130283
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
Methyltetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-126523
-
|
|
|
ADC Synthesis
Azide
|
|
N3-C5-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-126885
-
|
|
|
DBCO
ADC Synthesis
PROTAC Synthesis
|
|
DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140069
-
|
|
|
PROTAC Synthesis
BCN
|
|
endo-BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140762
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG24-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-126974
-
|
|
|
Alkynes
PROTAC Synthesis
ADC Synthesis
|
|
Propargyl-PEG3-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG3-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130388
-
|
|
|
ADC Synthesis
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG5-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140764
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-151827
-
|
|
|
DBCO
|
|
DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .
|
-
- HY-126522
-
|
|
|
ADC Synthesis
Azide
|
|
N3-C4-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-126520
-
|
|
|
ADC Synthesis
Azide
|
|
N3-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-126511
-
|
|
|
ADC Synthesis
Alkynes
|
|
Propargyl-C1-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC). Propargyl-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-126516
-
|
|
|
Alkynes
ADC Synthesis
|
|
Propargyl-PEG4-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130474
-
|
|
|
PROTAC Synthesis
ADC Synthesis
Azide
|
|
Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG6-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140757
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W096079
-
|
|
|
BCN
ADC Synthesis
|
|
BCN-endo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-endo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
-
- HY-151698
-
|
|
|
TCO
|
|
TCO-NHS Ester axial is a click chemistry reagent that can be used as a building block in amine reactions. TCO-NHS Ester axial contains TCO groups, which can undergo inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-174893
-
|
|
|
Azide
|
|
Azido-PEG20-NHS ester is a PEG derivative that can be used for drug delivery and other research. Azido-PEG20-NHS ester is a click chemistry reagent. Azido-PEG20-NHS contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group. Azido-PEG20-NHS can also undergo ring strain driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
|
-
- HY-170528
-
|
|
|
DBCO
|
|
DBCO-PEG3-NHS is a biochemical assay reagent, that can be used to chemically modify proteins and antibodies with an alkynyl (DBCO) or N-hydroxysuccinimide (NHS) ester group. DBCO-PEG3-NHS can be used as a linker in PROTAC synthesis or for drug delivery and the development of biosensors and diagnostic reagents .
|
-
- HY-126512
-
|
|
|
ADC Synthesis
Alkynes
|
|
Propargyl-C2-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC). Propargyl-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140070
-
|
|
|
PROTAC Synthesis
BCN
|
|
endo-BCN-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG8-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130551
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
Tetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG5-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-140756
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG1-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140759
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG10-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-D2746
-
|
|
|
Azide
|
|
Cy5.5 bis-NHS ester is a reactive cyanine dye containing NHS ester which can be used to label amine groups in peptides, proteins, and oligonucleotides.
|
-
- HY-141170
-
|
|
|
TCO
ADC Synthesis
PROTAC Synthesis
|
|
TCO-PEG12-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG12-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-151727
-
|
|
|
Tetrazine
|
|
Norbornene-NHS is a norbornene-functionalized antibody-drug conjugate linker (ADC Linker) bearing an NHS ester, which is applicable for highly efficient and specific antibody conjugation reactions in ADC research and development. Norbornene-NHS also acts as an azide-group-containing click chemistry reagent, serving as a dienophile for copper-free click reaction conjugation .
|
-
- HY-160773
-
|
|
|
DBCO
|
|
DBCO-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-140760
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG12-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-172355A
-
|
|
|
Azide
|
|
Azide-PEG-NHS (Mn 5000) is an azide PEG NHS ester that can be used for click chemistry reactions and can also be used to synthesize PEG hydrogels .
|
-
- HY-130385
-
|
|
|
PROTAC Synthesis
ADC Synthesis
Alkynes
|
|
Propargyl-PEG6-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG6-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130376
-
|
|
|
Alkynes
PROTAC Synthesis
ADC Synthesis
|
|
Propargyl-PEG8-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG8-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-174935
-
|
|
|
DBCO
|
|
DBCO-PEG1000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .
|
-
- HY-140271
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG1-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-138734
-
|
|
|
PROTAC Synthesis
Alkynes
|
|
Propargyl-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-141169
-
|
|
|
TCO
|
|
TCO-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-140761
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG16-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG16-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-135973
-
|
|
|
BCN
ADC Synthesis
|
|
BCN-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . BCN-SS-NHS is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-174935A
-
|
|
|
DBCO
|
|
DBCO-PEG2000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .
|
- HY-138744
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG13-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-141272
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-145090
-
|
|
|
PROTAC Synthesis
DBCO
ADC Synthesis
|
|
DBCO-N-bis(PEG4-NHS ester) is a PEG linker which contains two PEG4-NHS ester and a DBCO group. DBCO-N-bis(PEG4-NHS ester) is useful for protein modification or labeling. DBCO-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-156313
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Me-Tet-PEG4-NHS is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
- HY-138756
-
|
|
|
PROTAC Synthesis
DBCO
|
|
PC DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140139
-
|
|
|
Alkynes
ADC Synthesis
|
|
PC Alkyne-PEG4-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . PC Alkyne-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140758
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG9-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG9-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-138463
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG36-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG36-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-151742
-
|
|
|
TCO
|
|
Norbornene-methyl-NHS is a norbornene-based antibody-drug conjugate linker (ADC Linker) bearing methyl and NHS ester functional groups, which can be used for specific antibody conjugation. Norbornene-methyl-NHS is also a click chemistry reagent containing a TCO group, acting as a dienophile for conjugation via the Diels-Alder reaction, namely the copper-free click reaction with tetrazine .
|
- HY-126908
-
|
|
|
Tetrazine
PROTAC Synthesis
|
|
Tetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-174888
-
|
|
|
DBCO
|
|
DBCO-PEG16-NHS ester is a PEG derivative consisting of DBCO, PEG units, and NHS ester. NHS ester can bind to amino acids or other molecules containing amino groups. DBCO-PEG16-NHS ester contains a DBCO group and can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
|
- HY-130381
-
|
|
|
ADC Synthesis
Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG7-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG7-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-111456
-
|
|
|
PROTAC Synthesis
DBCO
ADC Synthesis
|
|
DBCO-NHCO-PEG4-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140068
-
|
|
|
BCN
PROTAC Synthesis
|
|
endo-BCN-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG3-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-133479
-
|
|
|
Tetrazine
PROTAC Synthesis
|
|
Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-NHCO-C3-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-W879040
-
|
|
|
DBCO
|
|
Sulfo-DBCO-NHS ester is a click chemistry reagent containing an azide group. The DBCO group is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. NHS ester can bind to amino acids or other molecules containing amino groups .
|
- HY-151686
-
|
|
|
Tetrazine
|
|
Bz-(Me)Tz-NHS is a methyltetrazine carboxylic acid NHS ester that enables conjugation of the tetrazine moiety to the 5' end of oligonucleotides via amide coupling reaction, and it is used in oligonucleotide template-mediated fluorescent bioorthogonal cycloaddition reactions. Bz-(Me) Tz-NHS is applicable to click chemistry-related studies .
|
- HY-174935C
-
|
|
|
DBCO
|
|
DBCO-PEG5000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .
|
- HY-141166
-
|
|
|
TCO
|
|
TCO-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
- HY-141168
-
|
|
|
TCO
|
|
TCO-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
- HY-140275
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-NHCO-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-156323
-
|
|
|
BCN
|
|
BCN-exo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-exo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
- HY-156324
-
|
|
|
BCN
|
|
BCN-exo-PEG8-NHS is an ADC Linker containing 8 PEG units. BCN-exo-PEG8-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
- HY-136032
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Tetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-141166A
-
|
|
|
TCO
|
|
(S,E)-TCO2-PEG3-NHS ester is NH2 reactive, and can be used in chemical synthesis. (S,E)-TCO2-PEG3-NHS ester contains TCO groups, which can undergo specific "click" reactions with tetrazine groups .
|
- HY-151758
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG12-NHS ester is a click chemistry reagent containing an azide group. Methyltetrazine-PEG12-NHS ester reacts with compounds containing TCO to form stable covalent bonds .
|
- HY-174935B
-
|
|
|
DBCO
|
|
DBCO-PEG3400-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .
|
- HY-174935D
-
|
|
|
DBCO
|
|
DBCO-PEG10000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .
|
- HY-141171
-
|
|
|
PROTAC Synthesis
TCO
|
|
TCO-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG24-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-141270
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-141271
-
|
|
|
Tetrazine
|
|
Methyltetrazine-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-141167B
-
|
|
|
TCO
ADC Synthesis
|
|
(S)-TCO-PEG4-NHS ester is an ADC linker containing 4 PEG units. (S)-TCO-PEG4-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
- HY-156491
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Me-Tet-PEG9-NHS is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
- HY-156476
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Me-Tet-PEG2-NHS is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
- HY-156490
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Me-Tet-PEG5-NHS is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
- HY-140276
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-NHCO-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG13-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-133375
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-NHCO-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG2-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-133371
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PROTAC Synthesis
DBCO
|
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DBCO-NHCO-C4-NHS ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-C4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-138707
-
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PROTAC Synthesis
Azide
|
|
Azido-PEG7-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG7-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-172355
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Azide
|
|
Azide-PEG-NHS (Mn 3500) is an azide PEG NHS ester that can be used for click chemistry reactions and can also be used to synthesize PEG hydrogels .
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- HY-140141
-
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PROTAC Synthesis
Tetrazine
|
|
PC Methyltetrazine-PEG4-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC Methyltetrazine-PEG4-NHS carbonate ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-141169A
-
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ADC Synthesis
TCO
|
|
(S)-TCO-PEG8-NHS ester is an ADC linker containing 8 PEG units. (S)-TCO-PEG8-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
- HY-136033
-
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|
ADC Synthesis
Tetrazine
|
|
Methyltetrazine-SS-NHS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-151698A
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TCO
|
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(S,E)-TCO-NHS Ester is a Click Amino Acid that can be used to label amine-containing compounds or biomolecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
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- HY-151698B
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TCO
|
|
(R,E)-TCO-NHS Ester is a Click Amino Acid that can be used to label amine-containing compounds or biomolecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
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- HY-140142
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Azide
PROTAC Synthesis
|
|
PC Azido-PEG11-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC Azido-PEG11-NHS carbonate ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-135959
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DBCO
PROTAC Synthesis
|
|
DBCO-NH-PEG7-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NH-PEG7-C2-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-174894
-
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Azide
|
|
Azido-PEG11-NHS ester is a PEG derivative that can be used for drug delivery and other research. Azido-PEG11-NHS ester is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group. It can also undergo ring strain driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
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- HY-160773A
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DBCO
|
|
DBCO-C3-amide-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-C3-amide-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
- HY-141268
-
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Tetrazine
|
|
Methyltetrazine-Sulfo-NHS ester (sodium) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-130390
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Alkynes
PROTAC Synthesis
|
|
Propargyl-PEG4-O-C1-NHS ester (compound 8) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-O-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-140767
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG8-C1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-C1-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-148840
-
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|
DBCO
|
|
Sulfo DBCO-PEG3-NHS ester is a click chemistry reagent containing an azide group. Sulfo DBCO-PEG3-NHS ester is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO group is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain and sulfo group increase water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only .
|
- HY-130931
-
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|
|
ADC Synthesis
Alkynes
|
|
Propargyl-NH-PEG3-C2-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-NH-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-133539
-
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|
|
ADC Synthesis
Alkynes
|
|
Propargyl-C8-amido-PEG2-NHS ester is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-C8-amido-PEG2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-115545
-
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|
|
ADC Synthesis
DBCO
|
|
DBCO-NHS ester 3 (Compound 12) is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 3 is a derivative of Dibenzylcyclooctyne (DBCO) obtained by activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC) . DBCO-NHS ester 3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-W190937
-
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Azide
|
|
PC Azido-PEG3-NHS carbonate ester is a photocleavable linker. It can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
- HY-154802
-
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|
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ADC Synthesis
TCO
|
|
TCO-GK-PEG4-NHS ester is an ADC Linker, and can be used for synthesis of [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d. [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d binds with high affinity and immunoreactivity to HER2 . TCO-GK-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-148840A
-
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DBCO
|
|
Sulfo DBCO-PEG3-NHS ester TEA is a click chemistry reagent containing an azide group. Sulfo DBCO-PEG3-NHS ester (TEA) is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO group is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain and sulfo group increase water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only .
|
- HY-164085
-
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|
Azide
|
|
Azide-C3-NHCO-C3-NHS ester is utilized as a linker in chemical synthesis, especially when rapid and specific ligation via click chemistry is required .
|
- HY-130312
-
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|
|
PROTAC Synthesis
Azide
|
|
N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker with a terminal azide group. N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is used in the synthesis of PROTACs N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-W1052510
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Azide
|
|
N3-PEG2-CH2CO2-NHS is a PEG derivative containing an azide group and an NHS ester. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
- HY-140582
-
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|
|
DBCO
PROTAC Synthesis
|
|
N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-133412
-
|
|
|
ADC Synthesis
DBCO
|
|
DBCO-NHCO-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-NHCO-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-133413
-
|
|
|
ADC Synthesis
DBCO
|
|
DBCO-CONH-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-CONH-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-126528
-
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|
|
ADC Synthesis
Azide
|
|
N3-PEG3-C2-NHS ester is a nonclaevable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-126526
-
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|
|
Azide
ADC Synthesis
|
|
N3-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG2-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-130109
-
|
|
|
ADC Synthesis
Azide
|
|
N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140585
-
|
|
|
DBCO
PROTAC Synthesis
|
|
N-DBCO-N-bis(PEG2-C2-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-DBCO-N-bis(PEG2-C2-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140766
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG5-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-138350
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG10-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG10-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-133431
-
|
|
|
ADC Synthesis
DBCO
|
|
DBCO-PEG3-SS-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG3-SS-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
- HY-140102
-
|
|
|
ADC Synthesis
Azide
|
|
Azidoethyl-SS-propionic NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azidoethyl-SS-propionic NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-167290
-
|
|
|
Azide
|
|
N-(Azido-PEG3)-N-bis(PEG3-NHS ester) is a trifunctional linker that can be used for synthesis of a bispecific heterodimer .
|
- HY-140763
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG1-CH2CO2-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG1-CH2CO2-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-133466
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Methyltetrazine-PEG4-SS-NHS ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-SS-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-136040
-
|
|
|
Tetrazine
ADC Synthesis
|
|
Tetrazine-PEG4-SS-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-PEG4-SS-NHS is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
- HY-140765
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG4-NHS-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-NHS-ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-141172A
-
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|
|
TCO
PROTAC Synthesis
|
|
TCO-PEG2-Sulfo-NHS ester sodium is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
- HY-126514
-
|
|
|
ADC Synthesis
Alkynes
|
|
Propargyl-O-C1-amido-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-O-C1-amido-PEG2-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-126515
-
|
|
|
Alkynes
ADC Synthesis
|
|
Propargyl-O-C1-amido-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-O-C1-amido-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-126524
-
|
|
|
Azide
ADC Synthesis
|
|
N3-Ph-NHS ester (compound 133) is an organic synthesis intermediate and ADC linker used for the synthesis of antibody-drug conjugate (ADC) molecules .
|
- HY-140560
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG4-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140561
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140559
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG2)-N-Boc-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-W096149
-
|
|
|
BCN
|
|
exo-BCN-NHS carbonate carbonate contains BCN group. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
|
- HY-133583
-
|
|
|
ADC Synthesis
Alkynes
|
|
Propargyl-O-C1-amido-PEG3-C2-NHS ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-O-C1-amido-PEG3-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-151769
-
|
|
|
TCO
Labeling and Fluorescence Imaging
|
|
TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent containing an azide group. TCO-PEG2-Sulfo-NHS ester is a PEG linker containing a TCO moiety and a sulfo-NHS ester moiety. The sulfo group makes this molecule soluble in waqueous buffer. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety. Reagent grade, for research use only . TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
- HY-140866
-
|
|
|
PROTAC Synthesis
Azide
|
|
N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azido-PEG4)-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140768
-
|
|
|
PROTAC Synthesis
Azide
|
|
Azido-PEG3-O-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-O-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-135966
-
|
|
|
Azide
ADC Synthesis
|
|
Azido-PEG3-SS-NHS is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG3-SS-NHS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-126525
-
|
|
|
Azide
ADC Synthesis
|
|
4-N3Pfp-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . 4-N3Pfp-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-141048
-
|
|
|
Azide
PROTAC Synthesis
|
|
N-(Azide-PEG3)-N'-(PEG4-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(Azide-PEG3)-N'-(PEG4-NHS ester)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140770
-
|
|
|
Azide
PROTAC Synthesis
|
|
Azido-PEG3-aminoacetic acid-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-aminoacetic acid-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-140865
-
|
|
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Azide
PROTAC Synthesis
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2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . 2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-W020546
-
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DBCO
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DBCO-amine TFA is a simple building block containing a DBCO moiety and an amine group. Amine is very reactive with NHS ester. DBCO is commonly used for copper-free Click Chemistry reactions.
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- HY-140339
-
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PROTAC Synthesis
Azide
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ANB-NOS is a heterobifunctional crosslinker with lipophilic, uncharged properties suitable for intracellular conjugation. ANB-NOS contains an amine-reactive Nhydroxysuccinimide (NHS) ester and a photoactivatable nitrophenyl azide. ANB-NOS can be used for the research of fibrosarcoma and mammary adenocarcinoma .
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- HY-24592
-
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TCO
PROTAC Synthesis
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(S,E)-Cyclooct-2-enol is a Click Amino Acid that can be used as a linker in the synthesis of PROTAC molecules. TCO-NHS ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.
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- HY-W590569
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Azide
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Azido-PEG12-amine is a water soluble PEG compound. The azide group enables Click Chemistry. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The hydrophilic PEG arm increases solubility in aqueous media.
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- HY-156301
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Tetrazine
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Methyltetrazine-amido-PEG8-amine Trifluoroacetate is a heterobifunctional linker containing a terminal methyltetrazine, which can react with TCO-containing compounds without the catalysis of Cu or elevated temperatures, and terminal amine, which reacts with NHS ester specifically and efficiently. The PEG spacer enhances water solubility.
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- HY-W879032
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BCN
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Endo-BCN-PEG4-Pomalidomide is a PEG derivative composed of BCN, PEG4 and Pomalidomide (HY-10984). The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
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- HY-W879045
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Endo-BCN-PEG5-NH2
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BCN
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Endo-BCN-PEG5-amine (Endo-BCN-PEG5-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
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- HY-42972
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ADC Synthesis
DBCO
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DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester ((HY-115524) and (HY-115545)), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
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- HY-W800653
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Azide
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N-(Azido-PEG3)-NH-PEG3-t-butyl ester is a click chemistry reagent with a terminal azide group and secondary amine NH group. NH group is reactive with NHS ester, The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The azide group can participate in Click Chemistry.
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- HY-42972G
-
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DBCO
|
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DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester ((HY-115524) and (HY-115545)), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
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- HY-W422109
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Tetrazine
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4-(6-Methyl-1,2,4,5-tetrazin-3-yl) benzoic acid is an asymmetric tetrazine derivative and a bioorthogonal reaction partner. 4-(6-Methyl-1,2,4,5-tetrazin-3-yl) benzoic acid can be conjugated with Bevacizumab (HY-P9906) via EDC/NHS activation while retaining the VEGF-binding affinity of the antibody, thus constructing a targeting agent for pretargeted immuno-PET/NIRF imaging .
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| Cat. No. |
Product Name |
|
Classification |
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- HY-W441011
-
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Phospholipids
|
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DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .
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-
- HY-W441014
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Pegylated Lipids
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DSPE-PEG2000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG2000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG2000-NHS can be used in the study of drug delivery .
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-
- HY-150241
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Phospholipids
|
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DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .
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-
- HY-W591424
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mPEG2000-SC; mPEG2000-Succinimidyl ester
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Polymers
|
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m-PEG2000-NHS ester (mPEG2000-SC) is a reagent with both cell adhesion inhibition and peptide conjugation functions. The NHS ester group of m-PEG2000-NHS ester forms stable amide bonds with primary amine-containing molecules (e.g., the N-terminus of MMP-2-cleavable octapeptide) to generate mPEG-peptide intermediates for liposome surface modification. When m-PEG2000-NHS ester is immobilized on a cystamine-modified gold surface, it can construct an in vitro model for cell adhesion kinetic studies, and higher PEG density and thicker layers correlate with lower cell adhesion rates. m-PEG2000-NHS ester can synthesize MMP-2-responsive PEGylated lipid conjugates to achieve MMP-triggered dePEGylation in the tumor microenvironment. m-PEG2000-NHS ester can be used in studies related to colon cancer and other conditions .
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-
- HY-174264
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Pegylated Lipids
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DMG-PEG2000-NHS is a polyethylene glycol lipid with a molecular weight of 2000, which can be used to construct novel drug delivery systems that confer mucoadhesive and cell-targeting capabilities to lipid nanoparticles .
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-
- HY-W441013
-
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|
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Pegylated Lipids
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DSPE-PEG1000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG1000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG1000-NHS can be used in the study of drug delivery .
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-
- HY-155909A
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mPEG1000-SC; mPEG1000-Succinimidyl ester
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Polymers
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m-PEG1000-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
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-
- HY-W440702
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Pegylated Lipids
|
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Cholesterol-PEG2000-NHS is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG2000-NHS can be used in drug delivery research .
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-
- HY-W441015A
-
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Pegylated Lipids
|
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DSPE-m-PEG3400-NHS is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine .
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-
- HY-157745
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mPEG40000-SC; mPEG40000-Succinimidyl ester
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Polymers
|
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m-PEG-NHS ester (mPEG-SC; mPEG-Succinimidyl ester) (MW 40000) is a polyethylene glycol derivative. m-PEG-NHS ester serves as a modifying agent that reacts with free amino groups on the surface of protein or polypeptide molecules to form stable amide bonds, thereby covalently linking PEG chains to biomacromolecules, improving their antigenicity and immunogenicity, and facilitating the preparation of injectable formulations .
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-
- HY-W441016
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|
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Pegylated Lipids
|
|
DSPE-PEG5000-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG5000-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG5000-NHS can be used in the study of drug delivery .
|
-
- HY-W440697
-
|
|
|
Pegylated Lipids
|
|
Cholesterol-PEG1000-NHS is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG1000-NHS can be used in drug delivery research .
|
-
- HY-155909C
-
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mPEG350-SC; mPEG350-Succinimidyl ester
|
|
Polymers
|
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m-PEG350-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
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-
- HY-W441002
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Phospholipids
|
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DSPE-succinic acid is a derivative of Succinic acid (HY-N0420) and an intermediate of DSPE-Doxorubicin. DSPE-succinic acid can be used to synthesize DSPE-Doxorubicin via EDC/NHS activation. DSPE-succinic acid is applicable to the research of triple-negative breast cancer .
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-
- HY-W440706
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Pegylated Lipids
|
|
Cholesterol-PEG2000-alcohol is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.
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-
- HY-W441012
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|
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Pegylated Lipids
|
|
DSPE-PEG600-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG600-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG600-NHS can be used in the study of drug delivery .
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-
- HY-W440927
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|
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Pegylated Lipids
|
|
Stearic acid-PEG2000-NHS is an amphiphatic PEG polymer which forms micelles in an aqueous solution for drug-loaded nanoparticles. The NHS ester is reactive with amine to form a stable amide bond. Reagent grade, for research purpose.
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-
- HY-W441014B
-
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|
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Pegylated Lipids
|
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DSPE-PEG20000-NHS ammonium is one of the most commonly used reactive phospholipids for coupling antibodies, proteins, peptides or other substrates to the surface of liposomes and other lipid PEG nanoparticles .
|
-
- HY-155909
-
|
mPEG3400-SC; mPEG3400-Succinimidyl ester
|
|
Polymers
|
|
m-PEG3400-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-W440704
-
|
|
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Pegylated Lipids
|
|
Cholesterol-PEG5000-NHS is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG5000-NHS can be used in drug delivery research .
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-
- HY-W441014A
-
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|
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Pegylated Lipids
|
|
DSPE-PEG10000-NHS ammonium is one of the most commonly used reactive phospholipids for coupling antibodies, proteins, peptides or other substrates to the surface of liposomes and other lipid PEG nanoparticles .
|
-
- HY-155909B
-
|
mPEG550-SC; mPEG550-Succinimidyl ester
|
|
Polymers
|
|
m-PEG550-NHS ester can be used to modify active molecules and improve their antigenicity, immunogenicity, and help prepare injection preparations. The modification of serine protease lumbrokinase (LK) by m-PEG-NHS ester does not affect its strong fibrinolytic and thrombolytic activities, and has good application prospects.
|
-
- HY-W440926
-
|
|
|
Pegylated Lipids
|
|
Stearic acid-PEG1000-NHS is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond.
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-
- HY-W440945
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|
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Pegylated Lipids
|
|
Stearic acid-PEG2000-amine is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The terminal amine can react with an NHS ester to form a stable amide linkage. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer. Reagent grade, for research use only.
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-
- HY-W440703
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Pegylated Lipids
|
|
Cholesterol-PEG3400-NHS is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG3400-NHS can be used in drug delivery research .
|
-
- HY-174264B
-
|
|
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Pegylated Lipids
|
|
DMG-PEG3400-NHS is a PEG derivative that can be used to construct drug delivery vehicles.
|
-
- HY-174264C
-
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|
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Pegylated Lipids
|
|
DMG-PEG5000-NHS is a PEG derivative that can be used to construct drug delivery vehicles.
|
-
- HY-W440928
-
|
|
|
Pegylated Lipids
|
|
Stearic acid-PEG3400-NHS is a phospholipid polyPEG which can self-assemble in water to form lipid bilayer. The polymer can be used to prepare liposomes as drug carrier to deliver nutrients/therpeutic agents, such as mRNA or DNA.
|
-
- HY-RS22963
-
|
|
|
siRNAs
Rat Pre-designed siRNA Sets
|
|
Nhs Rat Pre-designed siRNA Set A contains three designed siRNAs for Nhs gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
|
-
- HY-RS16532
-
|
|
|
siRNAs
Mouse Pre-designed siRNA Sets
|
|
Nhs Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nhs gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
|
-
- HY-W441005
-
|
|
|
Phospholipids
|
|
Amino-Gly-Gly-DSPE (hydrochloride) is a specially modified phospholipid that has been used to synthesize liposomes. The terminal amine is reactive with an NHS ester compound or carboxylic acid molecule in the presence of activator, such as HATU or EDC.
|
-
- HY-172270D
-
|
|
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Pegylated Lipids
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
-
- HY-172270
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
-
- HY-172270A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
-
- HY-W440807
-
|
|
|
Pegylated Lipids
|
|
Oleoyl-Gly-Lys-(m-PEG11)-NH2 is a PEG-lipid molecule featuring an oleoyl amide linked to a Gly-Lys dipeptide and a methoxy PEG11 chain on the C-terminus of the lysine. The lysine primary amine may be used in a wide variety of reactions with carboxylic acids, NHS esters, and carbonyl groups. The PEG linker provides aqueous solubility.
|
-
- HY-145547
-
|
14:0 Lyso PE; 1-Myristoyl-2-hydroxy-sn-glycero-3-PE; 1-Tetradecanoyl-sn-glycero-3-phosphoethanolamine
|
|
Phospholipids
|
|
1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells . Serum levels of 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine are elevated in patients with malignant breast cancer compared to healthy controls .
|
-
- HY-174264A
-
|
|
|
Pegylated Lipids
|
|
DMG-PEG1000-NHS is a PEG derivative that can be used to construct drug delivery vehicles.
|
-
- HY-182234
-
|
|
|
Phosphoramidites
Thymine
|
|
NHS-Carboxy-dT is a phosphoramidite that can be used in the synthesis of oligonucleotides.
|
-
- HY-W441014C
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG40000-NHS ammonium is one of the most commonly used reactive phospholipids for coupling antibodies, proteins, peptides or other substrates to the surface of liposomes and other lipid PEG nanoparticles .
|
-
- HY-RS09290
-
|
|
|
siRNAs
Human Pre-designed siRNA Sets
|
|
NHS Human Pre-designed siRNA Set A contains three designed siRNAs for NHS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
|
-
- HY-172270C
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG1000-PTP is synthesised by conjugating the amino group of plectin-1 peptide (PTP) with DSPE-PEG-NHS ester via amide bonds. DSPE-PEG1000-PTP can be used to construct drug delivery vectors .
|
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-42972G
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester ((HY-115524) and (HY-115545)), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
-
- HY-W1048843AG
-
|
4-Arm PEG5000-amine
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG5000-NH2 (GMP) (4-Arm PEG5000-amine (GMP)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
-
-
- HY-W1048843AGL
-
|
4-Arm PEG5000-amine (GMP Like)
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG5000-NH2 (GMP Like) (4-Arm PEG5000-amine (GMP Like)) is 4-Arm PEG-NH2 (HY-W1048843A) produced by using GMP like guidelines. GMP like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. 4-Arm PEG5000-NH2 is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .
|
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