1353016-71-3

DBCO-NHS ester Chemical Structure
1353016-71-3

Chemical Structure

DBCO-NHS ester

  • CAS No.: 1353016-71-3
  • Formula:C23H18N2O5
  • Molecular Weight:402.40

InChIKey: XCEBOJWFQSQZKR-UHFFFAOYSA-N

SMILES: O=C(CCC(ON(C(CC1)=O)C1=O)=O)N(C(C=CC=C2)=C2C#C3)CC4=C3C=CC=C4

Biological Activity: DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Cat. No. Product Name Purity Description Pricing
HY-42973 		DBCO-NHS ester 99.47% DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

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