1 Result for "

NSC 681239 (GMP)

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "NSC 681239 (GMP)" in MCE Product Catalog:

Bortezomib (GMP)
Bortezomib (GMP)
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Cat. No.: HY-10227G
Synonyms: PS-341 (GMP); LDP-341 (GMP); NSC 681239 (GMP)
Bortezomib (GMP) (PS-341 (GMP)) is Bortezomib (HY-10227) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Bortezomib can be used for the study of multiple myeloma (MM) . Bortezomib effectively inhibits TREM2 expression in tumor-associated macrophages (TAMs) .
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