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3 Results for "
NVS-PAK1-1
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "NVS-PAK1-1" in MCE Product Catalog:
5
5 Cited Publications
NVS-PAK1-1, a chemical probe, is a potent and selective allosteric PAK1 inhibitor with an IC50 of 5 nM .
Cat. No.: HY-100519R
CAS No.: 1783816-74-9
Target:
Research Areas:
NVS-PAK1-1 (Standard) is the analytical standard of NVS-PAK1-1 (HY-100519). This product is intended for research and analytical applications. NVS-PAK1-1, a chemical probe, is a potent and selective allosteric PAK1 inhibitor with an IC50 of 5 nM .
Cat. No.: HY-148821
CAS No.: 3009849-06-0
BJG-05-039 is an inhibitor targeting PAK1, with an IC50 of 233 nM against human PAK1. BJG-05-039 induces the selective degradation of PAK1 and inhibits its kinase activity by conjugating NVS-PAK1-1 (HY-100519) with Lenalidomide (HY-A0003) to recruit Cereblon. BJG-05-039 can be used in research related to breast cancer and ovarian cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
