1 Result for "

OA-Br-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "OA-Br-1" in MCE Product Catalog:

Cat. No.: HY-173165
Synonyms: 3-O-(6-Bromo-D-mannosyl)-28-acylamino-n-caprOAte methyl oleanolic acid
Target:  

Phosphatase Apoptosis

Research Areas:  

Cancer

OA-Br-1 is an orally active and selective inhibitor of PTP1B with an IC50 value of 7.08 μM. OA-Br-1 induces apoptosis. OA-Br-1 has broad spectrum anti-proliferative activity against cancer cells, and plays an anti-breast cancer role through the PTP1B/PI3K/AKT signaling pathway both in vitro and in vivo [1].
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