2. Natural Products
  3. Plants
  4. Papaveraceae
  5. Macleaya cordata (Willd.) R. Br.

Macleaya cordata (Willd.) R. Br.

Macleaya cordata (Willd.) R. Br. (13):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N4317
    Ethoxysanguinarine 28342-31-6 98.81%
    Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine is an inhibitor of protein phosphatase 2A (CIP2A). Ethoxysanguinarine induces cell apoptosis and inhibits colorectal cancer cells growth.
    Ethoxysanguinarine
  • HY-N7674
    Angoline 21080-31-9 99.67%
    Angoline is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation.
    Angoline
  • HY-N0902
    Dihydrosanguinarine 3606-45-9 99.98%
    Dihydrosanguinarine (13,14-Dihydrosanguinarine) is an alkaloid with antibacterial and anti-inflammatory activities, and also an important precursor of Sanguinarine (HY-N0052). Dihydrosanguinarine targets and regulates the TNF/IL-17/PI3K signaling pathway, downregulates the levels of pro-inflammatory factors such as IL-17A, TNF-α and IL-6, upregulates the expression of TGF-β, inhibits myeloperoxidase activity, and regulates the transcription of multiple inflammation-related genes. Dihydrosanguinarine exhibits antibacterial activity against a variety of oral microorganisms. Dihydrosanguinarine can be used in research related to liver inflammation and oral flora dysbiosis.
    Dihydrosanguinarine
  • HY-N3000
    6-Methoxydihydrosanguinarine 72401-54-8 99.88%
    6-Methoxydihydrosanguinarine is an alkaloid with activity across multiple cancer cell types. 6-Methoxydihydrosanguinarine activates IRE1/JNK signaling, blocks Akt/mTOR and PI3K/AKT/mTOR pathways, reduces expression of Cdc25C, CyclinB1, Cdc2, YAP/TAZ, Survivin, GPX4, and EGFR, upregulates IRE1 and DR5, and activates JNK and caspases. 6-Methoxydihydrosanguinarine induces apoptosis, G2/M phase arrest, DNA damage, ROS generation, lipid peroxidation, ferroptosis, autophagy, and suppresses cancer cell growth. 6-Methoxydihydrosanguinarine disruptes the biofilm formation of Candida albicans (C. albicans). 6-Methoxydihydrosanguinarine can be used for the research of non-small cell lung cancer, hepatocellular carcinoma, melanoma, colon carcinoma, ovarian cancer and breast cancer.
    6-Methoxydihydrosanguinarine
  • HY-N0903
    Dihydrochelerythrine 6880-91-7 99.39%
    Dihydrochelerythrine is a natural compound isolated from Corydalis yanhusuo; has antifungal activity.
    Dihydrochelerythrine
  • HY-N0052
    Sanguinarine 2447-54-3
    Sanguinarine (Sanguinarin), a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.
    Sanguinarine
  • HY-N2696
    6-Acetonyldihydrosanguinarine 37687-34-6 98.0%
    6-Acetonyldihydrosanguinarine is a compound isolated from the aerial parts of Chelidonium majus L..
    6-Acetonyldihydrosanguinarine
  • HY-N2359
    Chelerythrine 34316-15-9
    Chelerythrine is a natural alkaloid, acts as a potent and selective Ca2+/phospholopid-dependent PKC antagonist, with an IC50 of 0.7 μM. Chelerythrine has antitumor, antidiabetic and anti-inflammatory activity. Chelerythrine inhibits the BclXL-Bak BH3 peptide binding with IC50 of 1.5 μM and displaces Bax from BclXL. Chelerythrine triggers apoptosis and autophagy.
    Chelerythrine
  • HY-N1933
    Allocryptopine 485-91-6 99.53%
    Allocryptopine, a derivative of tetrahydropalmatine, is extracted from Macleaya cordata (Thunb.) Pers. Papaveraceae. Allocryptopine has antiarrhythmic effects and potently blocks human ether-a-go-go related gene (hERG) current.
    Allocryptopine
  • HY-N0052C
    Sanguinarine (gluconate) 132210-34-5
    Sanguinarine (Sanguinarin) gluconate, a benzophenanthridine alkaloid, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.
    Sanguinarine (gluconate)
  • HY-N7505
    Norchelerythrine 6900-99-8
    Norchelerythrine is an alkaloid isolated from the roots of Zanthoxylum capense with antibacterial activity against gram-positive and gram-negative bacteria. Norchelerythrine exhibits inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis and Escherichia coli with MIC values >50 µg/mL.
    Norchelerythrine
  • HY-N1933R
    Allocryptopine (Standard) 485-91-6
    Allocryptopine (Standard) is the analytical standard of Allocryptopine. This product is intended for research and analytical applications. Allocryptopine, a derivative of tetrahydropalmatine, is extracted from Macleaya cordata (Thunb.) Pers. Papaveraceae. Allocryptopine has antiarrhythmic effects and potently blocks human ether-a-go-go related gene (hERG) current.
    Allocryptopine (Standard)
  • HY-N10365
    6-(1-Hydroxyethyl)-5,6-dihydrochelerythrine 2715007-88-6
    6-(1-Hydroxyethyl)-5,6-dihydrochelerythrine, a alkaloid, significantly perturbates the features of cellular organelles including early endosomes, mitochondria and autophagosomes (Parkinson’s Disease patient-derived olfactory cells).
    6-(1-Hydroxyethyl)-5,6-dihydrochelerythrine