2. Natural Products
  3. Plants
  4. Papaveraceae
  5. Macleaya cordata (Willd.) R. Br.

Macleaya cordata (Willd.) R. Br.

Macleaya cordata (Willd.) R. Br. (13):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N7674
    Angoline 21080-31-9 99.67%
    Angoline is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation.
    Angoline
  • HY-N4317
    Ethoxysanguinarine 28342-31-6 99.73%
    Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine is an inhibitor of protein phosphatase 2A (CIP2A). Ethoxysanguinarine induces cell apoptosis and inhibits colorectal cancer cells growth.
    Ethoxysanguinarine
  • HY-N0902
    Dihydrosanguinarine 3606-45-9 99.98%
    Dihydrosanguinarine is a natural compound isolated from the leaves of Macleaya microcarpa; has antifungal and anticancer activity.
    Dihydrosanguinarine
  • HY-N0903
    Dihydrochelerythrine 6880-91-7 99.39%
    Dihydrochelerythrine is a natural compound isolated from Corydalis yanhusuo; has antifungal activity.
    Dihydrochelerythrine
  • HY-N3000
    6-Methoxydihydrosanguinarine 72401-54-8 99.88%
    6-Methoxydihydrosanguinarine is an lkaloid isolated from the fruits of M.cordata. 6-Methoxydihydrosanguinarine shows strong cytotoxicity against MCF-7 and SF-268 cell lines with IC50 values of 0.61 μM and 0.54 μM, respectively.
    6-Methoxydihydrosanguinarine
  • HY-N0052C
    Sanguinarine (gluconate) 132210-34-5
    Sanguinarine (Sanguinarin) gluconate, a benzophenanthridine alkaloid, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.
    Sanguinarine (gluconate)
  • HY-N2359
    Chelerythrine 34316-15-9
    Chelerythrine is a natural alkaloid, acts as a potent and selective Ca2+/phospholopid-dependent PKC antagonist, with an IC50 of 0.7 μM. Chelerythrine has antitumor, antidiabetic and anti-inflammatory activity. Chelerythrine inhibits the BclXL-Bak BH3 peptide binding with IC50 of 1.5 μM and displaces Bax from BclXL. Chelerythrine triggers apoptosis and autophagy.
    Chelerythrine
  • HY-N7674A
    Angoline hydrochloride 1071676-04-4
    Angoline hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline hydrochloride inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation.
    Angoline hydrochloride
  • HY-N0052
    Sanguinarine 2447-54-3
    Sanguinarine (Sanguinarin), a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.
    Sanguinarine
  • HY-N10365
    6-(1-Hydroxyethyl)-5,6-dihydrochelerythrine 2715007-88-6
    6-(1-Hydroxyethyl)-5,6-dihydrochelerythrine, a alkaloid, significantly perturbates the features of cellular organelles including early endosomes, mitochondria and autophagosomes (Parkinson’s Disease patient-derived olfactory cells).
    6-(1-Hydroxyethyl)-5,6-dihydrochelerythrine
  • HY-N2696
    6-Acetonyldihydrosanguinarine 37687-34-6
    6-Acetonyldihydrosanguinarine is a compound isolated from the aerial parts of Chelidonium majus L..
    6-Acetonyldihydrosanguinarine
  • HY-N4228
    6-Methoxydihydroavicine 151890-26-5
    6-Methoxydihydroavicine is an alkaloid isolated from Zanthoxylum integrifoliolum. 6-Methoxydihydroavicine has antiplatelet activities and inhibits AA-, collagen- and PAF-induced platelet aggregation in vitro.
    6-Methoxydihydroavicine
  • HY-N7505
    Norchelerythrine 6900-99-8
    Norchelerythrine is an alkaloid isolated from the roots of Zanthoxylum capense with antibacterial activity against gram-positive and gram-negative bacteria. Norchelerythrine exhibits inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis and Escherichia coli with MIC values >50 µg/mL.
    Norchelerythrine