1. JAK/STAT Signaling
    Stem Cell/Wnt
  2. STAT
  3. Angoline

Angoline 

Cat. No.: HY-N7674 Purity: 99.67%
Handling Instructions

Angoline is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation.

For research use only. We do not sell to patients.

Angoline Chemical Structure

Angoline Chemical Structure

CAS No. : 21080-31-9

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5 mg USD 180 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Angoline is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation[1].

IC50 & Target

IC50: 11.56 μM (IL6/STAT3 signaling pathway)

Molecular Weight

379.41

Formula

C₂₂H₂₁NO₅

CAS No.

21080-31-9

SMILES

CN1C2=C3C(C=C4OCOC4=C3)=CC=C2C5=C(C(OC)=C(OC)C=C5)C1OC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

References
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Keywords:

AngolineSTATIL-6STAT3phosphorylationanticancerproliferationInhibitorinhibitorinhibit

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Angoline
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