1. Apoptosis
  2. Apoptosis
  3. Ethoxysanguinarine

Ethoxysanguinarine 

Cat. No.: HY-N4317 Purity: ≥98.0%
Handling Instructions

Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine inhibits viability and induces apoptosis of colorectal cancer cells by inhibiting protein phosphatase 2A (CIP2A).

For research use only. We do not sell to patients.

Ethoxysanguinarine Chemical Structure

Ethoxysanguinarine Chemical Structure

CAS No. : 28342-31-6

Size Price Stock Quantity
5 mg USD 202 In-stock
Estimated Time of Arrival: December 31
10 mg USD 343 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine inhibits viability and induces apoptosis of colorectal cancer cells by inhibiting protein phosphatase 2A (CIP2A)[1].

Molecular Weight

377.39

Formula

C₂₂H₁₉NO₅

CAS No.

28342-31-6

SMILES

CN1C2=C3C(C=C4OCOC4=C3)=CC=C2C5=C(C6=C(OCO6)C=C5)C1OCC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 60 mg/mL (158.99 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6498 mL 13.2489 mL 26.4978 mL
5 mM 0.5300 mL 2.6498 mL 5.2996 mL
10 mM 0.2650 mL 1.3249 mL 2.6498 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 1.5 mg/mL (3.97 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

EthoxysanguinarineApoptosisInhibitorinhibitorinhibit

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Product Name:
Ethoxysanguinarine
Cat. No.:
HY-N4317
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