1 Result for "

PEAQX tetrasodium

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PEAQX tetrasodium" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-12294A
Purity:  ≥98.0%
Synonyms: NVP-AAM077 tetrasodium hydrate
Target:  

Apoptosis Caspase iGluR

Research Areas:  

Neurological Disease

PEAQX tetrasodium hydrate (NVP-AAM077 tetrasodium hydrate) is a tetrasodium hydrate of PEAQX (HY-12294). PEAQX tetrasodium hydrate is an orally active and selective NMDA antagonist, with IC50 values of 270 nM and 29.6 μM for hNMDAR 1A/2A and hNMDAR 1A/2B, respectively. PEAQX tetrasodium hydrate can promote the activation of caspase-3 and induce cell apoptosis in cortical striatal slice cultures .
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